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A New Pregnane Glycoside from Fermented Leaves of Agave americana

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Chinese Chemical Letters 2002年第12期13卷 1189-1192页

作者： jian ming jin Xi Kui LIU Chong Ren YANG State Key Laboratory of Phytochemistry and Plant Resources of West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650204

A new minor pregnane glycoside was isolated from the fermented leaves of Agave americana. Its structure was elucidated as (20S)-5a-pregnane-3? 20-diol 20-O--D-glucopyrano- side (1) by spectral methods.

关键词： Agave americana L. pregnane glycoside.

Two New Steroidal Glycosides from Fermented Leaves of Agave americana

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Chinese Chemical Letters 2002年第7期13卷 629-632页

作者： jian ming jin Xi Kui LIU Rong Wei TENG Chong Ren YANG Kunming Institute of Botany Chinese Academy of SciencesKunming 650204

Two new spirostanol glycosides named agamenoside A and B, were isolated from the fermented leaves of Agave americana. Their structures were elucidated as (23S, 25R)-5a -spirostan-3b, 6a, 23-triol 3-O-a-L-rhamnopyranosyl-(13)- b-D-glucopyranosyl-(12)-[b-D- xylopyranosyl-(13)]-b-D-glucopyranosyl-(14)-b-D-galactopyranoside (1) and (25R)-5a-spiro- stan-3b, 6a-diol 3-O-b-D-glucopyranosyl-(12)-[ b-D-xylopyranosyl-(13)]- b-D-glucopyra- nosyl-(14)- b-D-galactopyranoside (2) by a combination of chemical and spectral methods.

关键词： Agave americana L. steroidal glycosides agamenosides.

Spontaneous remission of acromegaly or gigantism due to subclinical apoplexy of pituitary growth hormone adenoma

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Chinese Medical Journal 2011年第22期124卷 3820-3823页

作者： WANG Xian-ling DOU jing-tao LU Zhao-hui ZHONG Wen-wen BA jian-ming jin Du LU Ju-ming PAN Chang-yu MU Yi-ming Department of Endocrinology Chinese People＇s Liberation Army General Hospital Beijing 100853 China

Background Subclinical apoplexy of pituitary functional adenoma can cause spontaneous remission of hormone hypersecretion. The typical presence of pituitary growth hormone （GH） adenoma is gigantism and/or acromegaly. We investigated the clinical characteristics of patients with spontaneous partial remission of acromegaly or gigantism due to subclinical apoplexy of GH adenoma. Methods Six patients with spontaneous remission of acromegaly or gigantism were enrolled. The clinical characteristics, endocrinological evaluation and imageological characteristics were retrospectively analyzed. Results In these cases, the initial clinical presences were diabetes mellitus or hypogonadism. No abrupt headache, vomiting, visual function impairment, or conscious disturbance had ever been complained of. The base levels of GH and insulin growth factor-1 （IGF-1） were normal or higher, but nadir GH levels were all still 〉1 μg/L in 75 g oral glucose tolerance test. Magnetic resonance imaging detected enlarged sella, partial empty sella and compressed pituitary. The transsphenoidal surgery was performed in 2 cases, and the other patients were conservatively managed. All the patients were in clinical remission. Conclusions When the clinical presences, endocrine evaluation, biochemical examination and imageology indicate spontaneous remission of GH hypersecretion in patients with gigantism or acromegaly, the diagnosis of subclinical apoplexy of pituitary GH adenoma should be presumed. To these patients, conservative therapy may be appropriate.

关键词： growth hormone adenoma subclinical apoplexy of pituitary adenoma acromegaly

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分布自由时基于可控提前期的契约适应性研究

运筹与管理 2017年第6期26卷 132-139页

作者：方新蹇明靳留乾重庆工商大学商务策划学院重庆400067 西南交通大学交通运输与物流学院四川成都610031 重庆邮电大学经济管理学院重庆400065

研究表明回购契约与收益共享契约具有等价性,然而二者却适用于不同的供应链。本文从提前期可控的视角并将供应链管理引入需求分布自由的市场环境,研究二者的适应性。首先构建一体化供应链系统的决策模型,基于模型推导其最优生产量和最... 详细信息

研究表明回购契约与收益共享契约具有等价性,然而二者却适用于不同的供应链。本文从提前期可控的视角并将供应链管理引入需求分布自由的市场环境,研究二者的适应性。首先构建一体化供应链系统的决策模型,基于模型推导其最优生产量和最优生产时点的存在性条件;然后分别以回购契约和收益共享契约作为激励机制,研究契约对单一供应商-零售商构成的二级分散供应链系统的适应性。结果表明,回购契约和收益共享契约均能协调供应链,但二者具有不同的适应性:当单位时间内边际生产成本增幅较大时,供应商偏好选择回购契约;提前压缩期越长,零售商越偏好选择收益共享契约。最后通过数值分析验证文章模型的有效性。

关键词：分布自由提前期契约适应性回购契约收益共享契约

Multiple liver metastases of unknown origin:A case report

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World Journal of Gastrointestinal Oncology 2025年第1期17卷 233-238页

作者： Ying-jin Wang Ze-Chuan Liu jian Wang Yin-Mo Yang Department of Hepatobiliary Pancreatic Surgery Peking University First HospitalBeijing 100034China Department of Interventional and Vascular Surgery Peking University First HospitalBeijing 100034China

BACKGROUND The liver is the most common site of digestive system tumor metastasis,but not all liver metastases can be traced back to the primary *** it is unusual,syphilis can impact the liver,manifesting as syphilitic hepatitis with inflammatory nodules,which might be misdiagnosed as *** SUMMARY This case report involves a 46-year-old female who developed right upper abdominal pain and intermittent low fever that persisted for more than three *** definitive diagnosis of a tumor had been made in the past decades,but signs of multiple liver metastases were recognized after a computed tomo-graphy scan without evidence of primary *** positive serological tests for syphilis and a biopsy of the liver nodules,a diagnosis of hepatic syphilis was made and confirmed with follow-up nodule reduction after anti-syphilis *** Clinicians must be aware of the possibility that syphilis can cause hepatic inflam-matory masses,especially when liver metastasis is suspected without evidence of primary lesions.A definitive diagnosis should be established in conjunction with a review of the patient’s medical history for accurate therapeutic intervention.

关键词： Syphilitic hepatitis Liver nodules Liver metastasis Treponema pallidum Case report

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基于USB2.0的实时视频图像传输

数据采集与处理 2004年第3期19卷 352-355页

作者：姚剑敏靳明宋建中中国科学院长春光学精密机械与物理研究所长春130033

比较了几种基于 USB技术的视频图像实时传输方案 ,针对视频图像在场消隐期间无有效数据的特点 ,提出了一种以场为单位分块传输的实时视频图像传输方案。以 USB2 .0接口芯片 Cy7c680 1 3为数据传输核心 ,采用块传输方式 ,利用了其 Slave ... 详细信息

比较了几种基于 USB技术的视频图像实时传输方案 ,针对视频图像在场消隐期间无有效数据的特点 ,提出了一种以场为单位分块传输的实时视频图像传输方案。以 USB2 .0接口芯片 Cy7c680 1 3为数据传输核心 ,采用块传输方式 ,利用了其 Slave FIFO(从 FIFO)异步读 /写接口模式的 Auto-In(自动打包 )工作机制。设计了适于高速图像采集的硬件系统 ,并编写了基于多线程技术的软件系统。测试结果表明 ,本系统传输速率达到 1 0 0 Mb/s,帧频达到 2 5帧 /s,实现了 80 0× 60 0图像的实时传输和显示。

关键词： USB2.0 实时视频图像传输块传输 Cy7c68013

Prognostic model for esophagogastric variceal rebleeding after endoscopic treatment in liver cirrhosis: A Chinese multicenter study

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World Journal of Gastroenterology 2025年第2期31卷 85-101页

作者： Jun-Yi Zhan Jie Chen jin-Zhong Yu Fei-Peng Xu Fei-Fei Xing De-Xin Wang ming-Yan Yang Feng Xing jian Wang Yong-Ping Mu Cell Biology Laboratory Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Institute of Liver Diseases Shanghai Academy of Chinese MedicineShanghai 201203China Clinical Key Laboratory of Traditional Chinese Medicine of Shanghai Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Key Laboratory of Liver and Kidney Disease of the Ministry of Education Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Gastroenterology and Hepatology Zhongshan Hospital Affiliated to Fudan UniversityShanghai 200032China Shanghai Institute of Liver Disease Fudan UniversityShanghai 200032China Evidence-Based Medicine Center Fudan UniversityShanghai 200032China Department of Gastrointestinal Endoscopy Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China Department of Hepatology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 201203China

BACKGROUND Rebleeding after recovery from esophagogastric variceal bleeding(EGVB)is a severe complication that is associated with high rates of both incidence and *** its clinical importance,recognized prognostic models that can effectively predict esophagogastric variceal rebleeding in patients with liver cirrhosis are *** To construct and externally validate a reliable prognostic model for predicting the occurrence of esophagogastric variceal *** This study included 477 EGVB patients across 2 cohorts:The derivation cohort(n=322)and the validation cohort(n=155).The primary outcome was rebleeding events within 1 *** least absolute shrinkage and selection operator was applied for predictor selection,and multivariate Cox regression analysis was used to construct the prognostic *** validation was performed with bootstrap *** assessed the discrimination,calibration and accuracy of the model,and performed patient risk *** Six predictors,including albumin and aspartate aminotransferase concentrations,white blood cell count,and the presence of ascites,portal vein thrombosis,and bleeding signs,were selected for the rebleeding event prediction following endoscopic treatment(REPET)*** predicting rebleeding within 1 year,the REPET model ex-hibited a concordance index of 0.775 and a Brier score of 0.143 in the derivation cohort,alongside 0.862 and 0.127 in the validation ***,the REPET model revealed a significant difference in rebleeding rates(P<0.01)between low-risk patients and intermediate-to high-risk patients in both *** We constructed and validated a new prognostic model for variceal rebleeding with excellent predictive per-formance,which will improve the clinical management of rebleeding in EGVB patients.

关键词： Esophagogastric variceal bleeding Variceal rebleeding Liver cirrhosis Prognostic model Risk stratification Secondary prophylaxis

考虑提前期压缩的Newsvendor型产品供应链契约协调模型

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管理工程学报 2017年第3期31卷 174-182页

作者：方新蹇明靳留乾周亚军西南交通大学交通运输与物流学院四川成都610031 西南交通大学智能控制开发中心四川成都610031 西南交通大学经济管理学院四川成都610031

时间管理是增强供应链竞争的优势之一,基于时间竞争的供应链管理核心在于提前期压缩。本文将提前期压缩视为可控决策变量,将批发价格结构、生产成本结构和市场需求的预测结构设定是关于提前期压缩的一般性范式函数关系,建立了考虑提前... 详细信息

时间管理是增强供应链竞争的优势之一,基于时间竞争的供应链管理核心在于提前期压缩。本文将提前期压缩视为可控决策变量,将批发价格结构、生产成本结构和市场需求的预测结构设定是关于提前期压缩的一般性范式函数关系,建立了考虑提前期压缩的Newsvendor型产品供应链契约协调模型。在一般性范式函数下的研究剔除了具体函数类型对问题的干扰,使得结论更具普遍性,更能突出提前期压缩的变动对供应链系统的最优决策和协调性的影响。文章首先证明考虑提前期压缩时集中供应链系统最优决策的存在性,并给出最优提前期压缩的求解方法和具体函数表达式;然后以回购契约和收益共享契约作为供应链管理的激励机制,讨论在考虑提前期压缩时,这两类契约对分散供应链系统的协调性。研究结果表明:回购契约和收益共享契约均可以协调供应链系统,但协调性受限于供应商的单位批发价格结构、单位生产成本结构以及零售商关于市场需求预测结构;最后通过数值分析验证文章结论的有效性,并对比分析回购契约与收益共享契约的等价性。

关键词：时间管理提前期压缩 Newsvendor型产品回购契约收益共享契约供应链协调

阈值随机共振及其在低质量浓度气体检测中的应用

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浙江大学学报（工学版） 2015年第1期49卷 15-19页

作者：童基均张光磊蔡强简锦明郭希山浙江理工大学信息学院浙江杭州310018 浙江清华长三角研究院科学仪器研究室浙江嘉兴314006 浙江大学生物系统工程与食品科学学院浙江杭州310058

提出利用阈值随机共振系统检测低质量浓度气体的方法.对传感器检测信号进行预处理以满足随机共振系统的要求,输入单阈值检测器,采用反映系统输入输出信号之间相关性的互相关系数作为阈值随机共振的表征.对系统的阈值参数进行优化,对最... 详细信息

提出利用阈值随机共振系统检测低质量浓度气体的方法.对传感器检测信号进行预处理以满足随机共振系统的要求,输入单阈值检测器,采用反映系统输入输出信号之间相关性的互相关系数作为阈值随机共振的表征.对系统的阈值参数进行优化,对最大互相关系数和气体质量浓度的相关性进行回归分析.实验结果表明,在该类系统中,不但存在阈值随机共振,而且随着气体质量浓度的增加最大互相关系数增加,采用最大互相关系数可以进行气体质量浓度的检测,最低检测限可以达到μg/L级别.

关键词：阈值随机共振互相关系数噪声强度低质量浓度气体