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Computerized cognitive remediation therapy on cognitive impairment and social function in patients with chronic schizophrenia

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World Journal of Psychiatry 2024年第6期14卷 884-893页

作者： jian-jun hu Xi-Rong Sun Shuang-Ming Ni Yan Kong Department of Psychiatry Shanghai Pudong New Area Mental Health Center(Mental Health Center of Tongji UniversityShanghai Pudong New Area Psychological Counseling Center)Shanghai 200124China

BACKGROUND Patients with schizophrenia may have various disease manifestations,most of which gradually tend toward incurable chronic decline,leading to mental *** basic symptoms of the disease can impair social function,whereas long-term hospitalization produces hospitalization syndrome,causing serious damage to social *** To investigate the effects of Computerized Cognitive Remediation Therapy(CCRT)on cognitive and social functioning in patients with chronic *** A retrospective analysis of 120 patients with chronic schizophrenia in Shanghai Pudong New Area Mental Health Center was *** were divided into an intervention group(60 cases treated with CCRT combined with conventional medication)and a control group(60 cases treated with conventional medication).After treatment,effects on cognitive function and social roles were observed in both *** Positive and Negative Syndrome Scale(PANSS)was used to assess the patients'psychiatric *** Wisconsin Card Sorting Test(WCST)was used to assess the patients'cognitive functioning,and the Social Functioning Scale for Psychiatric Inpatients(SSPI)was used to assess the social functioning of the inpatient psychiatric *** No significant differences were observed in the PANSS,WCST,and SSPI intergroup scores before treatment(P>0.05).After 2,4,and 6 wk of therapy,general psychopathological factors,positive symptoms,negative symptoms,and total PANSS scores of PANSS in the intervention group were lower than in the control group(P<0.05).After 2,4,and 6 wk of treatment,the number of false responses,number of persistent bugs,and total responses in the WCST were significantly lower in the intervention group than in the control group(P<0.05),and the amount of completed classification was significantly higher than in the control group(P<0.05).After 2,4,and 6 wk of therapy,the SSPI scores were significantly greater than those of the controls(P<0.05).After 6 wk of treatm

关键词： Computerized cognitive correction therapy Schizophrenia Cognitive function Social function Psychopathological factors

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Synthesis of a novel diether–ester conjugated model compound for electron donors of the polypropylene catalysts

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Chinese Chemical Letters 2013年第12期24卷 1106-1108页

作者： jian-jun hu Beijing Research Institute of Chemical Industry SINOPEC

A novel diether-ester conjugated electron donor model compound, 1,3-dimethoxypropan-2-yl benzoate, was synthesized via a reaction of 1,3-dimethoxypropan-2-ol and benzoyl chloride in the presence of triethyl amine and 4-dimethylaminopryidine. Compared to the known routes of preparing diethers, which usually employ the reactions to O-alkylate the corresponding diols with O-alkylating reagents, the presented method here provides a new way to prepare the diether electron donor compounds. It avoids employing the traditional O-alkylation reactions, so that highly toxic O-alkylating chemicals, such as iodomethane, and very strong basic deprotonating reagents, such as alkoxides or metal hydrides, are not required. The product can be obtained in high yields without complicated purification processes. Catalyst component containing the electron donor compound was prepared and used to catalyze propylene polymerization.

关键词： Ether Ester Electron donors Polypropylene catalyst

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The role of natural fracture activation in hydraulic fracturing for deep unconventional geo-energy reservoir stimulation

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Petroleum Science 2023年第4期20卷 2141-2164页

作者： jun Wang He-Ping Xie Stephan KMatthai jian-jun hu Cun-Bao Li Guangdong Provincial Key Laboratory of Deep Earth Sciences and Geothermal Energy Exploitation and Utilization Institute of Deep Earth Sciences and Green EnergyShenzhen UniversityShenzhen518060GuangdongPR China Shenzhen Key Laboratory of Deep Engineering Sciences and Green Energy College of Civil and Transportation EngineeringShenzhen UniversityShenzhen518060GuangdongPR China Department of Infrastructure Engineering University of MelbourneMelbourneVIC3010Australia MOE Laboratory of Deep Earth Science and Engineering Sichuan UniversityChengdu610065SichuanPR China

The presence of sealed or semi-sealed,multiscale natural fracture systems appears to be crucial for the successful stimulation of deep *** explore the reaction of such systems to reservoir stimulation,a new numerical simulation approach for hydraulic stimulation has been developed,trying to establish a realistic model of the physics *** new model successfully reproduces dynamic fracture activation,network generation,and overall reservoir permeability *** outputs indicate that natural fractures facilitate stimulation far beyond the near-wellbore area,and can significantly improve the hydraulic conductivity of unconventional geo-energy *** to our model,the fracture activation patterns are jointly determined by the occurrence of natural fractures and the in situ ***-density natural fractures,high-fluid pressure,and low effective stress environments promote the formation of complex fracture networks during *** or multicluster fracturing treatments with an appropriate spacing also increase the stimulated reservoir area(SRA).The simulation scheme demonstrated in this work offers the possibility to elucidate the complex multiphysical couplings seen in the field through detailed site-specific modeling.

关键词： Natural fractures DFM Unconventional geo-energy reservoir Fracture reactivation Hydraulic stimulation

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Oligouridylates Formation with N-(O,O'-Diisopropyl)-Phosphoryl Alanine in the presence of Poly(β-(N^7-Adeninyl)Ethyl Methacrylate)

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Chinese Chemical Letters 2001年第4期12卷 313-316页

作者： Hong Qi XIANG jian jun hu Yang jianG Yu Fen ZHAO Bioorganic Phosphorus Laboratory Department of ChemistrySchool of Life Science and EngineeringTsinghua UniversityBeijing 100084

The oligouridylates formation with N-(O,O-diisopropyl)-phosphoryl alanine in the presence of poly((-(N7-adeninyl)ethyl methacrylate) was studied. An increased yield by the presence of the polymeric nucleic acid analo... 详细信息

关键词： N-phosphoryl amino acid nucleoside interaction polymeric nucleic acid analog.

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Consolidation mechanism of gold concentrates containing sulfur and carbon during oxygen-enriched air roasting

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International Journal of Minerals,Metallurgy and Materials 2017年第4期24卷 386-392页

作者： Qian Li Fang-zhou Ji Bin Xu jian-jun hu Yong-bin Yang Tao jiang School of Minerals Processing and Bioengineering Central South University Changsha 410083 China

Consolidation in calcines is a common problem in the oxygen-enriched air roasting of refractory gold concentrates containing sulfur and carbon when the initial temperature is greater than 600°C. To determine the phases that caused consolidation, gold concentrates were roasted under different conditions and the calcines were mainly detected by X-ray diffraction (XRD). The possible underlying mechanism was then studied through comparisons of the XRD patterns of different calcines. The results indicated that the generation of calcium magnesium silicate, iron-doped calcium aluminosilicate, and calcium aluminate caused the consolidation. Furthermore, an enriched oxygen atmosphere accelerated the oxidation reaction and the emitted heat increased the local temperature in calcines. The local temperature was inferred to have increased to the generation temperature zone of the corresponding liquid phases. Oxidation of the pyrite and decomposition of the dolomite and muscovite mainly occurred at the initial stage of oxygen-enriched air roasting. Calcium was confirmed to be essential to the consolidation process. © 2017, University of Science and Technology Beijing and Springer-Verlag Berlin Heidelberg.

关键词： Calcination Calcium Consolidation Gold Mechanisms Mica Oxygen Silicates Sulfur X ray diffraction

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Analysis of workload of tank crew under the conditions of informatization

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Defence Technology（防务技术） 2014年第1期10卷 17-21页

作者： Ming MAO Fang XIE jian-jun hu Bo SU China North Vehicle Research Institute

A consensus has been reached that the tanks need to be integrated into the informatization battlefield. With the development of technology,the tank crew has being gradually decreased, so the research on two-soldier crew tank has become a hotspot. The workload of tank crew under the conditions of informatization is analyzed based on the combat mission of tank and the typical combat scenarios, and the impact of new technologies on workload is evaluated. The crew members in tank can be reduced from three to two, but it is necessary to substantially improve the automation of target search and the reliability of each subsystem and component.

关键词：信息化战场工作量坦克乘员作战任务工作负载目标搜索自动化

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A novel thermally-stable single-phase phosphor Ca_(2)InTaO_(6):Dy^(3+)for NUV-excited white LEDs

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Journal of Rare Earths 2024年第10期42卷 1855-1864页

作者： jian hu Ruirui Cui jun Zhang Peng Linghu Youzhen Shi Xiang Guo Key Laboratory of Micro-Nano-Electronics and Software Technology of Guizhou Province College of Big Data and Information EngineeringGuizhou UniversityGuiyang550025China College of Computer and Information Engineering Guizhou University of CommerceGuiyang550014China

The work focuses on the utilization of the conventional solid-state sintering procedure to synthesize white phosphors Ca_(2)InTaO_(6):xDy^(3+)(0.02≤x≤0.12).Utilizing X-ray diffraction,the phase structure of samples was examined,and the crystal structure was refined using the Rietveld method.A scanning electron microscope was used to analyze the microstructure of ***-principles calculations confirm that the indirect bandgap of Ca_(2)InTaO_(6)is 3.786 eV,The luminous properties and energy transfer mechanism of Ca_(2)InTaO_(6):xDy^(3+)were studied using photoluminescence ***^(4)F_(9/2)→^(6)H_(13/2)transition of Dy^(3+)ions is responsible for the greatest emission peak,which was measured at 575 *** to research,the lifespan falls as the concentration of Dy^(3+)doping amount rises because of frequent interaction and ene rgy transfer between Dy^(3+)*** correlated color temperature of the WLEDs packaged with Ca_(2)InTaO_(6):0.08Dy^(3+)is 4677 K and CIE 1931 chromaticity coordinates are(0.3578,0.3831).Meantime,the phosphor also shows outstanding te mperature stability property,which maintains 83.8%of its initial emission intensity at 450 K(activation energy of 0.1467 eV).The W-LEDs retain their performance for 100 min when powered at 3.4 V voltage and 600 mA current,demonstrating the packed W-LEDs'sustaine d operation at high temperatures.

关键词： Ca_(2)InTaO_(6):Dy^(3+)phosphors Thermal stability Photoluminescence W-LEDs Thermal imaging Rare earths

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Influence of cutterhead opening ratio on soil arching effect and face stability during tunnelling through non-uniform soils

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Underground Space 2024年第4期17卷 45-59页

作者： Xue-jian Chen Pei-Pei Fang Qiu-Nan Chen jun hu Kai Yao Yong Liu State Key Laboratory of Water Resources Engineering and Management Wuhan UniversityWuhan 430072China hubei Technology Innovation Center for Smart Hydropower Wuhan 430000China College of Civil Engineering Anhui Jianzhu UniversityHefei 230601China School of Civil Engineering Hunan University of Science and TechnologyXiangtan 411201China School of Civil and Architectural Engineering Hainan UniversityHaikou 570228China School of Qilu Transportation Shandong UniversityJinan 250002China

Tunnelling has increasingly become an essential tool in the exploration of underground space.A typical construction problem is the face instability during tunnelling,posing a great threat to associated *** face instability often occurs with the soil arching *** study investigates the combined effect of cutterhead opening ratio and soil non-uniformity on soil arching effect and face stability,via conducting random finite-element analysis coupled with Monte–Carlo *** results underscore that the face stability is strongly associated with the evolution of stress *** obtained stability factors in the uniform soils can serve as a reference for the design of support pressure in practical tunnelling *** addition,non-uniform soils exhibit a lower stability factor than uniform soils,which implies that the latter likely yields an underestimated probability of face *** tunnel face is found to have a probability of failure more than 50%if the spatial non-uniformity of soil is *** the end,a practical framework is established to determine factor of safety(FOS)corresponding to different levels of probability of face failure considering various opening ratios in non-uniform *** required FOS is 1.70 to limit the probability of face instability no more than 0.1%.Our findings can facilitate the prediction of probability of instability in the conventionally deterministic design of face pressure.

关键词： Tunnel Face stability Soil arching effect Cutterhead opening ratio Non-uniform soil Random field

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A Novel Synthesis of Methyl 4, 6-O-Benzylidene-α-D-Glucopyranoside 2, 3-Cyclic Phosphite Ethyl Ester

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Chinese Chemical Letters 1999年第6期10卷 457-458页

作者： jian jun hu Yong JU Yu Fen ZHAO(Bioorganic Phosphorus Chemistry Laboratory, Department of Chemisrty.Tsinghua University. Beijing. 100084) Tsing hua Univ Bioorgan Phosphorus Chem Lab Dept Chem Beijing 100084 Peoples R China

A new compound. methyl 4. 6-O-benzylidene-a-D-glucopyranoside 2. 3-cyclicphosphite ethyl ester was synthesized via the reaction of methyl 4. 6-O-benzylidene-a-D-glucopyranoside and ethyl dichlorophosphite. Its structu... 详细信息

关键词： 2. 3-Cyclic glucopyranosyl phosphite ester synthesis structure determination

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A Study of Immunological Indices for Diagnosis of Chronic Berylliosis

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Biomedical and Environmental Sciences 1989年第4期2卷 318-324页

作者： YAO jian-jun hu SU-YING hunan Research Institute for Labor Protection against Nonferrous Metal,Changsha,hunan,China human Research Institute for Labor Protection against Nonferrous Metal Changsha Hunan China.

The results of the Be-induced leukocyte migration inhibition test(Be-MIT),the lymphocyte transformation test(LI),the E-rosette formation test(E-RFC),the old tuberculin test(OT),and sero-immunoglobulin(IgG,IgA,IgM)measurements on 13 cases of berylliosis,44 members of the observation group,and 51 members of the contact group are rè*** the Be-MIT,2 of the berylliosis patients were new cases that had been diagnosed and treated for a long time,and both tested positive(18%).Fourteen patients from the observation group tested positive(32%), and 15 from the contact group tested positive(30%).The 8 cases in the control group tested negative;7 patients from the observation group and 3 of the berylliosis cases tested negative after being *** lymphocyte transformation rates of the observation group and the berylliosis group were significantly lower than that of the control group(P<0.01).Both Et-RFC and Ea- RFC contents in the group with berylliosis were much lower than those in the control group(P <0.01).OT tests were performed on 8 berylliosis patients and 10 healthy *** patients showed negative reactions and one showed a positive *** the healthy men showed positive *** IgG and IgA levels of the observation group were significantly higher than those of the control group(P<0.01).The Be-MIT could detect active beryllium disease at an early stage as well as Be-sensitive *** test could be used as a supplementary diagnostic index for the differential diagnosis of berylliosis and for the evaluation of a curative effect.1989 Academic Press,Inc.

关键词： In A Study of Immunological Indices for Diagnosis of Chronic Berylliosis

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