检索结果-南通市图书馆

Current Medical Science 2021年第3期41卷 565-571页

作者： Ajith Bemardin Raj Li-fei lian Feng XU Guo LI Shan-shan huang Qi-ming lianG Kai LU jian-ling ZHAO Fu-rong WANG Department of Neurology Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China

There are few studies regarding imaging markers for predicting postoperative rebleeding after stereotactic minimally invasive surgery(MIS)for hypertensive intracerebral haemorrhage(ICH),and little is known about the relationship between satellite sign on computed tomography(CT)scans and postoperative rebleeding after *** study aimed to determine the value of the CT satellite sign in predicting postoperative rebleeding in patients with hypertensive ICH who undergo stereotactic *** retrospectively examined and analysed 105 patients with hypertensive ICH who underwent standard stereotactic MIS for hematoma evacuation within 72 h following *** rebleeding occurred in 14 of 65(21.5%)patients with the satellite sign on baseline CT,and in 5 of the 40(12.5%)patients without the satellite *** diiTerence was statistically *** and negative values of the satellite sign for predicting postoperative rebleeding were 21.5%and 87.5%,*** logistic regression analysis verified that baseline ICH volume and intraventricular rupture were independent predictors of postoperative *** conclusion,the satellite sign on baseline CT scans may not predict postoperative rebleeding following stereotactic MIS for hypertensive ICH.

关键词： intracerebral haemorrhage minimally invasive surgery satellite sign computed tomography postoperative rebleeding

对比重组人促红素不同频率给药方式在维持性血液透析患者中应用的疗效及安全性

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透析与人工器官 2024年第2期35卷 21-24页

作者：罗建平罗奇雨刘莲香罗玖莲刘小静郭鸿遂川县人民医院江西吉安343900 遂川县中医院江西吉安343900

目的探究对比重组人促红素不同频率给药方式在维持性血液透析患者中应用的疗效及安全性。方法选取2021年5月~2023年10月我院收治的维持性血液透析患者72例,采用随机数字表达法将其分为对照组和观察组,每组各36例。两组均使用重组人促红... 详细信息

目的探究对比重组人促红素不同频率给药方式在维持性血液透析患者中应用的疗效及安全性。方法选取2021年5月~2023年10月我院收治的维持性血液透析患者72例,采用随机数字表达法将其分为对照组和观察组,每组各36例。两组均使用重组人促红素辅助治疗,对照组每周多次给药,观察组每周单次给药,对比两组铁代谢情况[血清铁蛋白(SF)、血红蛋白水平(Hb)、转铁蛋白饱和度(TSAT)]、治疗效果以及不良反应。结果治疗前,两组SF、Hb、TSAT水平对比,不具有显著差异(P>0.05);治疗4周、12周后,两组SF、Hb、TSAT水平逐渐提升,高于治疗前,观察组高于对照组,具有显著差异(P0.05)。结论重组人促红素每周单次给药能改善患者贫血情况,提升治疗效果,同时保证治疗安全性。

关键词：重组人促红素不同频率维持性血液透析治疗效果肝功能不良反应

Absolute density measurement of nitrogen dioxide with cavity-enhanced laser-induced fluorescence

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Chinese Physics B 2018年第10期27卷 260-265页

作者： Zheng-Hai Yang Yong-Cheng Yang lian-Zhong Deng jian-Ping Yin State Key Laboratory of Precision Spectroscopy School of Physics and MaterialEast China Normal UniversityShanghai 200062China

The absolute number density of nitrogen dioxide（NO2） seeded in argon is measured with cavity-enhanced laserinduced fluorescence（CELIF） through using a pulsed laser beam for the first time. The cavity ring down（CRD） signal is acquired simultaneously and used for normalizing the LIF signal and determining the relationship between the measured CELIF signal and the NO2 number density. The minimum detectable NO2 density down to（3.6±0.1）10^8 cm^-3 is measured in 60 s of acquisition time by the CELIF method. The minimum absorption coefficient is measured to be（2.0±0.1）10^-9 cm^-1, corresponding to a noise equivalent absorption sensitivity of（2.2±0.1）10^9 cm.^-1Hz^-1/2. The experimental system demonstrated here can be further improved in its sensitivity and used for environmental monitoring of outdoor NO2 pollution.

关键词： cavity-enhanced laser-induced fluorescence (CELIF) cavity ring down (CRD)

Response of prostate cancer to addition of dutasteride after progression on abiraterone

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Asian Journal of Andrology 2021年第2期23卷 222-223页

作者： jian-Po lian Yuan-Yuan Gao Jing-Jie Tang Xi Chen Ying Liu Deng-Long Wu Zhen-Fei Li Sheng-Song huang Department of Urology Tongji HospitalTongji University School of MedicineShanghai 200065China State Key Laboratory of Cell Biology Shanghai Institute of Biochemistry and Cell BiologyCenter for Excellence in Molecular Cell ScienceChinese Academy of SciencesUniversity of Chinese Academy of SciencesShanghai 200031China

Dear Editor,Abiraterone has achieved great success in clinic by targeting cytochrome P45017A1(CYP17A)for prostate cancer therapy.1,2 However,drug resistance is inevitable and novel strategy is urgently *** previous work unveils a steroidal metabolic pathway for abiraterone in patients.3,4 Steroidogenic enzyme 3β-hydroxysteroid dehydrogenase 1(3βHSD1)catalyzes abiraterone toΔ4-abiraterone(D4A),which is further catalyzed to 5α-abiraterone(5α-Abi)by steroid-5α-reductase(SRD5A).The metabolite 5α-Abi binds to androgen receptor(AR)directly and activates AR signaling.

关键词： abiraterone CYP17 cancer

Power Adjusting Algorithm： A New Cross-Layer Power Saving Mechanism for Mobile Ad-Hoc Networks

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Journal of Computer Science & Technology 2013年第1期28卷 42-53页

作者： Jin-Tao Meng jian-Rui Yuan Sheng-Zhong Feng lian-Sheng Tan Shenzhen Institutes of Advanced Technology Chinese Academy of Sciences Shenzhen 518055 China Institute of Computing Technology Chinese Academy of Sciences Beijing 100190 China Graduate University of Chinese Academy of Sciences Beijing 100049 China Central South University Changsha 410083 China School of Information Science and Engineering Central China Normal University Wuhan 430079 China

Power saving is one of the key issues in Mobile Ad-Hoc Networks （MANETs）. It can be realized in Medium Access Control （MAC） layer and network layer. However, previous attentions were mainly paid to MAC layer or network layer with the aim of improving the channel utilization by adopting variable-range transmission power control. In this paper we focus on the power saving in both MAC layer and network layer, and propose a Power Adjusting Algorithm （PAA）. In the presence of host＇s mobility, PAA is designed to conserve energy by adjusting the transmission power to maintain the route＇s connectivity and restarting the route discovery periodically to find a new route with better energy efficiency dynamically. After analyzing the operations of PAA, we find that the length of route discovery restarting period is a critical argument which will affect power saving, and an energy consumption model is abstracted to find the optimal value of the restarting period by analyzing the energy consumption of this algorithm. PAA can handle the mobility of MANET by adjusting the transmission power and in the meantime save energy by restarting route discovery periodically to balance the energy consumption on route discovery and packet delivering. Simulation results show that, PAA saves nearly 40% energy compared with Dynamic Source Routing protocol when the maximum speed of mobile hosts is larger than 8 m/s.

关键词： mobile ad-hoc networks mobility control power control power efficiency

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图书馆旅游信息开发初探

图书馆论坛 2002年第3期22卷 111-113页

作者：黄坚段连秀黄勇中国地质大学图书馆湖北武汉430074 中国地质大学出版社湖北武汉430074 武汉长山学校湖北武汉430074

尽管旅游业现已成为国家支柱产业 ,但旅游学在图书馆学中还没有相应的地位 ,未能形成完整的学科 ,本文就图书馆如何开发旅游信息服务做了阐述 ,从理论高度上提出了旅游信息开发利用的原则 ,并结合实际做了一次有益的探索。

关键词：旅游信息独特性系统性市场导向图书馆旅游信息服务旅游信息资源开发利用

Treatment of cryptococcal meningitis with low-dose amphotericin B and flucytosine

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Chinese Medical Journal 2012年第2期125卷 385-387页

作者： Yan Dong huang jian-rong lian jiang-shan Li Lan-juan Zhejiang Univ Coll Med Affiliated Hosp 1 State Key Lab Diag & Treatment Infect Dis Hangzhou 310003 Zhejiang Peoples R China

Background Amphotericin B （0.7 mg/kg） with flucytosine is the standard treatment for cryptococcal ***,the long treatment course can induce adverse reactions in patients; therefore,reducing the dose may decrease such *** performed a retrospective analysis of treatment effects and adverse reactions when amphotericin B （0.4 mg/kg or 0.7 mg/kg per day） and flucytosine were used together to treat HIV-negative patients with cryptococcal *** Retrospective analysis was conducted on inpatients at the First Affiliated Hospital,College of Medicine,Zhejiang University （January 2005 to December 2009）.Low- or high-dose amphotericin B （0.4 or 0.7 mg/kg per day,respectively） plus flucytosine was *** negative conversion rate of Cryptococcus in the cerebrospinal fluid （CSF）,patient mortality,and the incidence of side effects for the two groups （low- ***-dose） were compared immediately after treatment and 2 and 10 weeks *** were analyzed by the Student＇s t test,chi-square tests using SPSS 12.0 statistical *** Two weeks post-treatment,Cryptococcus negative CSF rates were 78% （18/23） in the low-dose group and 87% （13/15） in the high-dose group （P=0.28）.Ten weeks post-treatment,both groups were *** mortality rate was 8% （2/25） in the low-dose group and 17% （3/18） in the high-dose group （P=-0.25）.There was a statistically significant difference in the incidence of adverse events between the groups,48% （12/25） and 78% （14/18） in the low- and high-dose groups,respectively （P=0.04）.Adverse events that required a change in treatment program in the low-dose group were 12% （3/25） compared to 39% （7/18） in the high-dose group （P=-0.04）.Conclusion Low-dose treatment regimens were better tolerated

关键词： meningitis, cryptococcal amphotericin B, flucytosine therapeutics, cerebrospinal fluid

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色氨酸代谢与肝纤维化

世界华人消化杂志 2024年第3期32卷 192-198页

作者：吴辉星龙昌锐张振华陈宇莲王炎玉乡世健周本杰中山大学附属第七医院药学部广东省深圳市518107 深圳市中药活性物质筛选与转化重点实验室广东省深圳市518107

肝纤维化是一种肝脏组织在长期炎症状态下持续损伤和自我修复形成纤维化瘢痕的过程,以细胞外基质过度沉积为特征的病理综合征.目前肝纤维化常见的病因包括酒精性脂肪肝炎、非酒精性肝炎、胆汁淤积性肝病、化学性肝损伤、病毒性肝炎等.... 详细信息

肝纤维化是一种肝脏组织在长期炎症状态下持续损伤和自我修复形成纤维化瘢痕的过程,以细胞外基质过度沉积为特征的病理综合征.目前肝纤维化常见的病因包括酒精性脂肪肝炎、非酒精性肝炎、胆汁淤积性肝病、化学性肝损伤、病毒性肝炎等.肝纤维化是肝硬化和肝功能衰竭的主要前期阶段,在持续炎症刺激下,若不加以控制,可能会进一步发展成肝硬化,乃至肝癌,对患者的治疗负担和生存质量产生重要影响.近年来,研究表明色氨酸及其代谢产物在肝纤维化的发生和进展中起着重要的调控作用,本文将综述色氨酸代谢与肝纤维化的相关研究进展,以期深入了解其潜在的治疗价值.

关键词：色氨酸代谢肝纤维化发病机制

Optimal spectral phase control of femtosecond laser-induced up-conversion luminescence in Sm^3+:NaYF4 glass

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Frontiers of physics 2020年第2期15卷 63-68页

作者： jian-Ping Li lian-Zhong Deng Ye Zheng Peng-Peng Ding Tian-Qing Jia Zhen-Rong Sun jian-Rong Qiu Shi-An Zhang State Key Laboratory of Precisicm Spectroscopy School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200062China State Key Laboratory of Modem Optical Instrumentation College of Optical Science and EngineeringZhejiang UniversityHangzhou 310027China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

The spectral phase of the femtosecond laser field is an important parameter that affects the up-conversion(UC)luminescence efficiency of dopant lanthanide *** this work,we report an experi-mental study on controlling the UC lmiiinescence efficiency in Sm^3+:NaYF4 glass by 800-nm femtosec-ond laser pulse shaping using spectral phase *** optimal phase control strategy efficiently enhances or suppresses the UC luminescence *** on the laser-power dependence of the UC luminescence intensity and its comparison with the luminescence spectrum under direct 266-nm fem-tosecond lciser irradiation,we propose herein an excitation model combining non-resonant two-photon absorption with resonance-media ted three-photon absorption to explain the experimental observations.

关键词： up-conversion luminescence rare earth ions quantum control femtosecond laser spectral phase

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负离子源中性束注入器智慧能源管理系统设计

核聚变与等离子体物理 2024年第1期44卷 30-35页

作者：丁健李逸斌蒋才超宋士花刘胜段练徐康幸刘智民谢远来合肥学院先进制造工程学院合肥230601 中国科学院合肥物质科学研究院等离子体物理研究所合肥230031 安徽大学物质科学与信息技术研究院合肥230601

为保障负离子源中性束注入(NNBI)系统用电的电能质量和稳定性,设计一套智慧能源管理系统。该系统以西门子PLC及分布式I/O系统为控制核心,通过对供配电系统各回路状态监控,基于Modbus通讯协议与多功能表的信息交互,实现对用电系统能耗监... 详细信息

为保障负离子源中性束注入(NNBI)系统用电的电能质量和稳定性,设计一套智慧能源管理系统。该系统以西门子PLC及分布式I/O系统为控制核心,通过对供配电系统各回路状态监控,基于Modbus通讯协议与多功能表的信息交互,实现对用电系统能耗监测及管理。通过可视化人机交互界面设计,为实验运行人员提供直观便捷的系统状态诊断工具。该系统具备一定的兼容性和扩展能力。相关台面测试表明,智慧能源管理系统运行稳定,控制可靠,能满足供配电系统的智能化管理和监测需求。

关键词：中性束注入智慧能源管理系统 Modbus通讯人机交互界面