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环泊酚与丙泊酚麻醉维持在老年腹腔镜结直肠癌根治术患者中的应用比较

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广东医学 2024年第6期45卷 706-711页

作者：甘川彭伟龙黄静翔陈健蔡炼杰曹阳贵州医科大学麻醉学院贵州贵阳550004 广州市红十字会医院麻醉科广东广州510220

目的探讨环泊酚与丙泊酚麻醉维持在老年腹腔镜结直肠癌根治术患者中的应用比较。方法共纳入医院收治的80例行腹腔镜结直肠癌根治术老年患者。随机分为观察组和对照组,每组40例。观察组采用环泊酚麻醉维持,对照组采用丙泊酚麻醉维持。比... 详细信息

目的探讨环泊酚与丙泊酚麻醉维持在老年腹腔镜结直肠癌根治术患者中的应用比较。方法共纳入医院收治的80例行腹腔镜结直肠癌根治术老年患者。随机分为观察组和对照组,每组40例。观察组采用环泊酚麻醉维持,对照组采用丙泊酚麻醉维持。比较两组患者不同时间点炎症因子水平、血流动力学指标、MMSE评分及不良反应。结果两组患者T1~T4时点心率(HR)、收缩压(SBP)及舒张压(DBP)均呈下降趋势,T4~T7时点呈上升趋势,组内比较差异有统计学意义(P24 h白细胞介素-6(IL-6)与肿瘤坏死因子-α(TNF-α)均低于对照组(P2.50%(1/40),显著低于对照组的25.00%(10/40),差异有统计学意义(P3、D5 MMSE评分均高于对照组(P24 h炎性因子水平差值、不良反应发生情况少,同时对患者术后MMSE评分影响小。

关键词：环泊酚丙泊酚麻醉维持老年腹腔镜结直肠癌根治术

航空发动机热防护超临界CO_(2)闭式循环方案设计

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航空发动机 2024年第4期50卷 88-94页

作者：李星剑连华奇李育隆徐思远马旭北京航空航天大学能源与动力工程学院北京100083 北京航空航天大学先进航空发动机协同创新中心北京100083 北京动力机械研究所北京100074

针对航空飞行器高速飞行时发动机热环境严峻、冷源有限的问题,提出了一种应用于航空发动机热防护、以超临界CO_(2)为工质的闭式布雷顿冷却循环方案。采用能量分析法构建布雷顿循环的数学模型,对比分析了简单循环、回热循环与间冷循环3... 详细信息

针对航空飞行器高速飞行时发动机热环境严峻、冷源有限的问题,提出了一种应用于航空发动机热防护、以超临界CO_(2)为工质的闭式布雷顿冷却循环方案。采用能量分析法构建布雷顿循环的数学模型,对比分析了简单循环、回热循环与间冷循环3种循环结构的优劣,比较了高温部件冷却通道的串并联结构对循环性能的影响。结果表明:回热循环能够提高系统热效率约4%,但热沉利用率降低50%;间冷循环能够降低系统热沉消耗8%,但会导致系统总质量增大;超临界CO_(2)简单循环是最符合发动机中间工质冷却循环工作需求的循环结构。对于简单循环而言,高温部件冷却通道并联结构的热效率比串联结构的高6%,但需要的碳氢燃料质量流量提高了2.7%,在碳氢燃料质量充足的条件下,并联结构的性能更优。

关键词：热防护闭式布雷顿循环超临界CO_(2) 循环结构航空发动机高超声速飞行器

Telomerase activity and human telomerase reverse transcriptase expression in colorectal carcinoma

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World Journal of Gastroenterology 2006年第3期12卷 465-467页

作者： jian-lun Liu lian-ying Ge Gui-nian Zhang Department of Gastrointestinal and Breast Surgery the Affiliated Cancer Hospital of Guangxi Medical UniversityNanning 530021 Guangxi Zhuang Autonomous Region China Department of Endoscope the Affiliated CancerHospital of Guangxi Medical University Nanning 530021Guangxi Zhuang Autonomous Region China Department-of Gastrointestinal Surgery Guangxi Zhuang Autonomous Region Hospital Narming 530021Guangxi Zhuang Autonomous Region China

AIM： To study the activity of telomerase and the expression of human telomerase reverse transcriptase （hTERT） in colorectal carcinoma and its adjacent tissues, normal mucosa and adenomatoid polyp, and to evaluate their relation with carcinogenesis and progression of colorectal carcinoma. METHODS： Telomerase activity and hTERT expression were determined in 30 samples of colorectal carcinoma and its adjacent tissues, normal mucosa and 20 samples of adenomatoid polyp by modified telomeric repeat amplification protocol （TRAP）, enzyme-linked immunosorbent assay （ELISA） and immunohistochemical method. RESULTS： Telomerase activity and hTERT expression were 83.33% （25/30） and 76.67% （23/30） respectively in colorectal carcinoma, which were obviously higher than those in paracancerous tissues （13.33%, 16.67%）, normal mucosa （3.33%, 3.33%） and adenomatoid polyp （10%, 10%）. There was a significant difference between colorectal carcinoma and other tissues （P=0.027）. The telomerase activity and hTERT expression were higher in colorectal carcinoma with lymphatic metastasis than in that without lymphatic metastasis （P=0.034）. When the histological classification and clinical stage were greater, the telomerase activity and hTERT expression increased, but there was no significant difference between them. In colorectal carcinoma, the telomerase activity was correlated with hTERT expression （positive vs negative expression of telomerase activity and hTERT, P=0.021）. CONCLUSION： Telomerase activity is closely correlated with the occurrence, development and metastasis of colorectal carcinoma. Overexpression of hTERT may play a critical role in the regulation of telomerase activity.

关键词： Colorectal carcinoma Telomerase activity hTERT expression

Synthesis of Methyl-substituted Phthalazinone-based Aromatic Poly(amide imide)s

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Chinese Chemical Letters 2002年第9期13卷 824-825页

作者： Xiu Ling ZHU Xi Gao jian lian Zhou CHEN Department of Polymer Science&Materials Dalian University of TechnologyDalian 116012

A series of novel aromatic poly ( amide imide)s containing phthalazinone moieties were prepared from 2-(4-aminophenyl)-4-[3-methyl-4-(4-aminophenoxy)-2,3-phthalazinone-1], a novel diamine 1 with four diimide-dicarboxylic acids by Yamazaki phosphorylation method with the inherent viscosity of 0.36~0.65 dL/g. These polymers had high glass transition temperatures above 300C and they lost 10% weight between 426~475C in N2. The structure of diamine 1 and the polymers was confirmed by IR, 1H NMR and MS. The obtained polymers were readily soluble in polar solvents such as NMP, m-cresol etc. and easily cast into tough, flexible films. The X-ray indicated that they are all amorphous.

关键词： Aromatic poly(amide imide) phthalazinone synthesis heat-resistance.

Mechanical Performances and Morphology of LDPE/UHMWPE Single-Polymer Composites Produced by Extrusion-Calendering Method

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Journal of Beijing Institute of Technology 2018年第1期27卷 155-160页

作者： jian Wang Ziran Du Tong lian Jiong Peng School of Chemistry and Chemical Engineering Beijing Institute of Technology

Extrusion-calendering method was developed to prepare single-polymer composites（SPCs） of ultrahigh molecular weight polyethylene（ UHMWPE） fabric reinforcing low density polyethylene（LDPE）.Differential scanning calorimeter（DSC） experiments were executed to determine the setup of extrusion *** of the die temperature on the tensile and interfacial performances of SPCs were studied through the tensile and T-peel tests,respectively. The results showed that both tensile strength and modulus increased initially and decreased afterwards as the temperature increased. The peak values of tensile strength and modulus of PE SPCs,which are 10. 8 and 3. 5 times as high as those of the unreinforced LDPE respectively,were obtained at 150 ℃. Higher temperatures also give a positive effect on peel strength. Scanning electron microscopy（ SEM） and camera were also used to observe the morphology of the SPCs samples.

关键词： extrusion-calendering single-polymer composites(SPCs) tensile performances peel strength morphology

Synthesis and properties of a star-shaped organic material with triphenylamine and N-vinyl carbazole units

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Chinese Chemical Letters 2007年第8期18卷 920-922页

作者： Qing Guo He jian Gong Cheng Feng lian Bai Shanghai Institute of Microsystem and Information Technology Chinese Academy of Sciences Shanghai 200050 China Key Laboratory of Organic Solids Centre for Molecular Science Institute of Chemistry Chinese Academy of Sciences Beijing 100080 China

A starburst tripbenylamine cored N-vinyl carbazole （V-Cz） branched compound was designed and synthesized via optimized Heck reaction in a yield of 40-60%. Moderate yield came from decomposition of V-Cz and self-coupling of triiodo-triphenylamine. TCz-TPA adopts a highly twisted propeller conformation by molecular mechanical optimization. It is readily soluble for its highly twisted conformation. Transparent and pinhole free films could be easily fabricated by spin-coating for its starburst structure. It emits blue-greenish light in CH2Cl2 peaked at 460 nm with a narrow full-width at half-maximum （FWHM） of 65 nm. As compared,

关键词： Starburst Triphenylamine Carbazole Heck reaction Photoluminescence

Experimental Study and Finite Element Analysis on Ultimate Strength of Dual-Angle Cross Combined Section Under Compression

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Computer Modeling in Engineering & Sciences 2019年第6期119卷 499-539页

作者： Hao Hu jian He lian Song Zhifeng Zhan Zhengliang Li School of Architectural Engineering Chongqing University of Arts and SciencesChongqing402160China Institute of Civil Engineering Disaster Prevention and Reduction Chongqing University of Arts and SciencesChongqing402160China School of Civil Engineering Chongqing UniversityChongqing400045China

This paper investigates Q420 dual-angle cross combined section columns under axial and eccentric compression by conducting *** specimen parameters,experimental setup,and test results are *** showed that local buckling occurred apparently for single internode specimens(λ35)under axial compression,while overall bending buckling appeared for others,and no torsional buckling *** theoretical formulas on stability factor were derived by the energy ***-linear finite element models considering residual stress were established using ANSYS which were verified by the corresponding experimental *** parametric study was to evaluate the effects of slenderness ratio(λ),width to thickness ratio of angles(b/t),the number of filled plate(n),load relative eccentricity(e)and the lateral support stiffness on the ultimate strengths of dual-angle cross combined section *** on above analysis,the design equations are proposed by using curve fitting *** is shown from comparison between test results,finite element analysis and related specifications that the ultimate strength from theoretical formulas,proposed equations and finite element models are consistent with experiments results.

关键词： Double angle combined section experimental finite element analysis

Organocatalytic Domino Michael/cyclization for the synthesis of highly substituted 4, 5-dihydrothiophenes

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Chinese Chemical Letters 2018年第3期29卷 517-520页

作者： Chen-Hao Ding jian-lian Dong Li-Si-Han Yu jian-Wu Xie Department of Chemistry and Life science Zhejiang Normal University Jinhua 321004 China

Based on an umpolung strategy, a series of novel full substituted, optically active dihydrothiophenes, which contain several functional groups, such as amine, ester and oxime groups, were obtained via an efficient org... 详细信息

关键词： Dihydrothiophenes Organocatalysis 1 3-Dicarbonyl compounds Thioamides Nitrostyrenes

Production of laccase by Coriolus versicolor and its application in decolorization of dyestuffs: (Ⅱ) Decolorization of dyes by laccase containing fermentation broth with or without self-immobilized mycelia

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Journal of Environmental Sciences 2003年第1期15卷 5-8页

作者： LIN jian ping lian Wei XIA Li ming CEN Pei lin Department of Chemical Engineering and Bioengineering Zhejiang UniversityHangzhou 310027China.

The capability of decolorization for commercial dyes by Coriolus versicolor fermentation broth containing laccase with or without immobilized mycelium was evaluated. With cell free fermentation broth containing laccase, high decolorization ratio was achieved for acid orange 7, but not for the other dyes concerned. The immobilized mycelium was proved to be more efficient than the cell free system. All the four dyestuffs studied were found being decolourized with certain extent by immobilized mycelium. The repeated batch decolorization was carried out with satisfactory results. The experimental data showed that the continuous decolorization of wastewater from a printing and dyeing industry was possible by using the self immobilized C. Versicolor.

关键词： laccase textile dyes immobilized mycelium decolorization Coriolus versicolor