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China’s Geological Science and Technology Has Made New Progress during 2018

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Acta Geologica Sinica(English Edition) 2019年第3期93卷 785-786页

作者： LIU lian LIU Zhiqiang huang Min FEI Hongcai ZHOU jian ZHANG Yuxu HAO Ziguo Chinese Academy of Geological Sciences China Geological Society

(1)Major scientific and technological innovations have been made in the Deep Continental Scientific Drilling Project of the Songliao Basin,Well Songke 2 has a drilling depth of 7018 *** large-bore coring technology system for ultra-deep wells has overcome major technical problems in deep exploration of the earth,such as ultra-high temperature drilling technology,and has created four world *** kinds of clean energy sources with a good exploration and development potential,i.e..

关键词： China Geological Science Technology

Unification of Filled Function and Tunnelling Function in Global Optimization

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Acta Mathematicae Applicatae Sinica 2007年第1期23卷 59-66页

作者： Wei Wang Yong-jian Yang lian-sheng Zhang Department of Mathematics East China University of Science and Technology Shanghai 200237 China Department of Mathematics Shanghai University Shanghai 200444 China

In this paper, two auxiliary functions for global optimization are proposed. These two auxiliary functions possess all characters of tunnelling functions and filled functions under certain general assumptions. Thus, they can be considered as the unification of filled function and tunnelling function. Moreover, the process of tunneling or filling for global optimization can be unified as the minimization of such auxiliary functions. Result of numerical experiments shows that such two auxiliary functions are effective.

关键词： Nonlinear programming global optimization filled function tunnelling function unification

研究型教学模式在研究生课程中应用的探索与思考——以“木材化学基础”课程为例

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教育教学论坛 2024年第31期 125-128页

作者：李建国黄六莲陈礼辉吴慧福建农林大学材料工程学院福建福州350108

实行教学与研究的有机结合,充分调动学生的积极性,对于更好地服务于高等农林院校特色专业的高素质人才培养具有重要的现实意义。以“木材化学基础”课程为例,针对课程建设背景、教学方法、考核措施,分析了该课程的教学现状。从优化教学... 详细信息

实行教学与研究的有机结合,充分调动学生的积极性,对于更好地服务于高等农林院校特色专业的高素质人才培养具有重要的现实意义。以“木材化学基础”课程为例,针对课程建设背景、教学方法、考核措施,分析了该课程的教学现状。从优化教学内容、教学方法、评价体系等方面提出了“木材化学基础”课程研究型教学模式的改革措施。在教学过程中有效融合学科知识与学科发展动态和研究热点,激发学生的学习兴趣,拓宽学生的视野,提升研究生的创造力,提高“木材化学基础”的教学效率和教学质量。

关键词：木材化学基础研究型教学教学改革

Application of GIS technology in chemical emergency response

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Journal of Environmental Sciences 2000年第2期12卷 47-52页

作者： Wang, Gui-lian Lu, Yong-Long Xu, jian Sino-Canadian High-tech Center of Resources and Environment Research Center for Eco-Environmental Sciences Chinese Academy of Sciences Beijing 100085 China

Responding to concerns raised by the Bhopal accident, more and more attention has been paid to local emergency, especially chemical emergency, prevention and planning worldwide, and many chemical emergency response systems for public response personnel have been built. With the successful application of geographical information system (GIS) technology in many fields, GIS can be an efficient tool for effective response to chemical emergencies. The purpose of this paper is to introduce the application of GIS technology in emergency response. Typical GIS technology is simply introduced and some of its existing applications to emergency, mainly natural disaster, response are summarized. Spatial data and spatial analysis requirements for chemical monitoring and emergency response are also discussed in detail. Finally a chemical monitoring and emergency response system under development by combining GIS and expert system for both chemical distribution centers and public response personnel is presented.

关键词： GIS chemical emergency emergency response chemical management expert system CLC number: X14 Document code: A

Molecular characteristics and structure–activity relationships of food-derived bioactive peptides

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Journal of Integrative Agriculture 2021年第9期20卷 2313-2332页

作者： YANG Fu-jia CHEN Xu huang Mu-chen YANG Qian CAI Xi-xi CHEN Xuan DU Ming huang jian-lian WANG Shao-yun Key Laboratory of Refrigeration and Conditioning Aquatic Products Processing of Ministry of Agriculture and Rural Affairs Xiamen 361022P.R.China College of Biological Science and Technology Fuzhou UniversityFuzhou 350108P.R.China College of Chemical Engineering Fuzhou UniversityFuzhou 350108P.R.China School of Food Science and Technology Dalian Polytechnic UniversityDalian 116034P.R.China Fujian Anjoy Foods Co. Ltd.Xiamen 361022P.R.China

Peptides are functional active fragments of proteins which can provide nutrients needed for human growth and development,and they also have unique physiological activity characteristics relative to *** peptides contain a great deal of development *** specifically,food-derived bioactive peptides have the advantages of a wide variety of sources,unique structures,high efficiency and safety,so they have broad development *** review provides an overview of the current advances regarding the preparation,functional characteristics,and structure–activity relationships of food-derived bioactive ***,the prospects for the future development and application of food-derived bioactive peptides are *** review may provide a better understanding of foodderived bioactive peptides,and some constructive inspirations for further research and applications in the food industry.

关键词： food-derived proteins bioactive peptides molecular characteristics structure–activity relationship

Synthesis and ion exchange properties for Cs^+ of ammonium-type mordenite

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Rare Metals 2015年第10期34卷 752-756页

作者： Dian-Quan Dong jian-Guo Zheng Xian-lian Han College of Chemical Engineering School of Qingdao University of Science and Technology

Cesium content in the seawater is 3.0 9 10-4 mg·L-1, and ammonium-type mordenite was used to exchange cesium from cesium source. K-type mordenite was obtained by hydrothermal synthesis method. After ammonium-modified, ion exchange properties such as saturated ion exchange capacities and selectivity coefficients for alkali metal ions were determined. At the same time, ion exchange isothermal curves of ammonium-type mordenite for Cs+ and NH4+ were determined at 25°*** electrolyte solution theory was used to work out activity coefficients of the system, and the Kielland diagram of the ion exchange system was obtained. The calculated equilibrium constant(Ka) and ion free enthalpy(DG0) of mordenite for Cs+ and NH4+ are 1.455 and -930.3J·mol-1, respectively, indicating that ion exchange process of ammonium-type mordenite for cesium is a spontaneous process.

关键词： Ion exchange Thermodynamics Mordenite Cesium

A serum metabolomic analysis for diagnosis and biomarker discovery of primary biliary cirrhosis and autoimmune hepatitis

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Hepatobiliary & Pancreatic Diseases International 2015年第4期14卷 413-421页

作者： jiang-Shan lian Wei Liu Shao-Rui Hao De-Ying Chen Yin-Yin Wang jian-Le Yang Hong-Yu Jia jian-Rong huang Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases State Key Laboratory for Diagnosis and Treatment of Infectious Disease First Affiliated Hospital Zhejiang University School of Medicine Yantai City Hospital for Infectious Diseases

Because of the diversity of the dinical and laboratory manifestations, the diagnosis of autoimmune liver disease （AILD） remains a challenge in clinical practice. The value of metabolomics has been studied in the diagnosis of many diseases. The present study aimed to determine whether the metabolic profiles, based on ultraperformance liquid chromatography-mass spectrometry （UPLC-MS）, differed between autoimmune hepatitis （AIH） and primary biliary cir- rhosis （PBC）, to identify specific metabolomic markers, and to establish a model for the diagnosis of AIH and PBC. METHODS： Serum samples were collected from 20 patients with PBC, 19 patients with AIH, and 25 healthy individuals. UPLC-MS data of the samples were analyzed using principal component analysis, partial least squares discrimination analysis and or- thogonal partial least squares discrimination analysis. RESULTS： The partial least squares discrimination analysis model （R2y=0.991, Q2=0.943） was established between the AIH and PBC groups and exhibited both sensitivity and speci- ficity of 100%. Five groups of biomarkers were identified, in- eluding bile acids, free fatty acids, phosphatidylcholines, lyso- lecithins and sphingomyelin. Bile acids significantly increased in the AIH and PBC groups compared with the healthy con- trol group. The other biomarkers decreased in the AIH andPBC groups compared with those in the healthy control group. In addition, the biomarkers were downregulated in the AIH group compared with the PBC group. CONCLUSIONS： The biomarkers identified revealed the pathophysiological changes in AILD and helped to discrimi- nate between AIH and PBC. The predictability of this method suggests its potential application in the diagnosis of AILD.

关键词： autoimmune liver disease biomarkers metabolomics autoimmune hepatitis primary biliary cirrhosis overlap syndrome

Mutation of DELAYED GREENING1 impairs chloroplast RNA editing at elevated ambient temperature in Arabidopsis

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Journal of Genetics and Genomics 2020年第4期47卷 201-212页

作者： Jingliang Sun Yingying Tian Qichao lian jian-Xiang Liu State Key Laboratory of Genetic Engineering School of Life SciencesFudan UniversityShanghai200433China State Key Laboratory of Plant Physiology and Biochemistry College of Life SciencesZhejiang UniversityHangzhou310027China

Chloroplasts are important for plant growth and *** editing in chloroplast converts cytidines(Cs)to uridine s(Us)at specific transcript positions and provides a correction mechanism to restore conserved codons or creates start or stop ***,the underlined molecular mechanism is not yet fully unders *** the present study,we identi fied a thermo-sensi tive mutantin leaf color 1(tst1)and found that TSL1 is allelic to DELAYED GREENING 1(DG1).The mis sense mutation of DG1 in tsl1 mutant confers a high temperature sensitivity and impaired chloroplast development at an elevated ambient temperature in *** analysis showed that chloroplast RNA editing at seve ral sites including accD-2568,ndhD-2,and petL-5 is impaired in tsl1 mutant plants grown at an elevated ***1 interacts with MORF2 and other proteins such as DYW1 and DYW2 involved in chloroplast RNA *** vitro RNA electrophoretic mobility shift assay demonstrated that DG1 binds to RNA targets such as accD,ndhD,and ***,our results revealed that DG1 is important for maintaining chloroplast mRNA editing in Arabidopsis.

关键词： Chloroplast development mRNA editing Warm temperature

Upper Bound Solution of the Resisting Moment Bearing Capacity of A Composite Bucket Shallow Foundation of An Offshore Wind Turbine in Sand

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China Ocean Engineering 2022年第6期36卷 859-870页

作者： LIU Run LI Tian-liang CHEN Guang-si lian Ji-jian State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China

Bearing the large moment that is generated by the wind load that acts on the upper structure of offshore wind turbines is an important feature of their foundations that is different from other offshore structures.A composite bucket shallow foundation(CBSF)has been proposed by Tianjin University to address the soft geological conditions in the offshore regions of China for wind *** CBSF is a new type of foundation and is effective against large *** soil deformation test of a CBSF and the numerical simulation study under the same working conditions are carried out to determine the failure mechanism of a CBSF under moment *** resisting soil compression rateηm is defined as a new empirical parameter that indicates the ability of the soil inside the bucket to resist moment *** upper limit of the resisting moment bearing capacity of the bucket foundation is derived through the upper bound theorem of classical plasticity theory based on the failure *** calculation method is validated by tests of bucket models with different height-diameter ratios in sand under moment loading.

关键词： bucket foundation failure mechanism resisting moment bearing capacity upper bound theorem resisting soil compression rate