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Study on Control Technology of Slag Composition for Low-Sulfur and Low-Oxygen Steel

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Journal of Iron and Steel Research International 2011年第S2期18卷 195-200页

作者： ZHANG Min, ZENG jian-hua, pan Hong (panGang Group Research Institute Co Ltd, Chengdu 611731, Sichuan, China) panGang Grp Res Inst Co Ltd Chengdu 611731 Sichuan Peoples R China

In order to reduce the content of oxygen and sulfur in steel, and produce low-sulfur and low-oxygen steel, study on slag has been carried out. Refining slag system of CaO-SiO2-Al2O3 is put forward with the consideration of slag amount from converter, oxidizability of slag and activity of oxygen in molten steel. On this basis, refining slagging system for low-sulfur and low-oxygen steel has been developed combined with the modification of slag from converter and composition control of refining slag in LF treatment process. The results show that oxygen content is not more than 15×10-6, as well as sulfur content is as low as 0.005% in tube blank steel. And it achieves the production of low-sulfur and low-oxygen steel.

关键词： ladle slag refining slag desulphurization low-oxygen steel low-sulfur steel

KINETIC STUDY ON THE EXTRACTION OF PALLADIUM(Ⅱ) WITH BIS(2-ETHYLHEXYL)SULFIDE

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Chinese Chemical Letters 1992年第6期3卷 463-464页

作者： jian Sheng GU jian hua pan Han Zhang WANG Department of Chemistry, Suzhou University, Suzhou, 215006

The effects of concentration, temperature, stirring rate and specific interfacial area on the extraction of Pd (Ⅱ) with bis(2--ethylhexyl) sulfide (DEHS) were studied by the use of a constant interracial area cell. T... 详细信息

关键词： WITH BIS ETHYLHEXYL)SULFIDE KINETIC STUDY ON THE EXTRACTION OF PALLADIUM

Comparative genomic study of gastric epithelial cells co-cultured with Helicobacter pylori

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World Journal of Gastroenterology 2012年第48期18卷 7212-7224页

作者： Fen Wang Li-Dan Luo jian-hua pan Li-hua huang Hong-Wei Lv Qin Guo Can-Xia Xu Shou-Rong Shen Department of Gastroenterology The Third Xiangya HospitalCentral South University Department of Gastroenterology Hunan Provincial Hospital

AIM:To identify genes potentially involved in Helicobacter pylori(***)-induced gastric ***:GES-1 cells were co-cultured with *** strains isolated from patients with gastric carcinoma(GC,n = 10) or chronic gastritis(CG,n = 10) for in vitro proliferation and apoptosis assays to identify the most and least virulent *** two strains were cagA-genotyped and used for further in vivo carcinogenic virulence assays by infecting Mongolian gerbils for 52 wk,respectively;a broth free of *** was lavaged as *** profiles of GES-1 cells cocultured with the most and least virulent strains were determined by microarray *** most differentially expressed genes were further verified using quantitative real-time polymerase chain reaction in GES-1cells infected with the most and least virulent strains,and by immunohistochemistry in *** positive CG,precancerous diseases,and GC biopsy specimens in an independent ***:GC-derived *** strains induced a potent proliferative effect in GES-1 cells in co-culture,whereas CG-derived strains did *** most(from a GC patient) and least(from a CG patient) virulent strains were cagA-positive and negative,*** week 52,CG,atrophy,metaplasia,dysplasia,and GC were observed in 90.0%,80.0%,80.0%,90%,and 60.0%,respectively,of the animals lavaged with the most virulent ***,only mild CG was observed in 90% of the animals lavaged with the least virulent *** microarray analysis,800 differentially expressed genes(49 up-and 751 down-regulated),involving those associated with cell cycle regulation,cell apoptosis,cytoskeleton,immune response,and substance and energy metabolisms,were identified in cells co-cultured with the most virulent strain as compared with those co-cultured with the least virulent *** six most differentially expressed genes(with a betweenness centrality of 0.1-0.2) were identified among the significant differential gene prof

关键词： Helicobacter pylori Gastric carcinoma Proliferation Genomic profiles

Numerical Study on Turbulence mixing of Planar Shock Accelerated Triangular Heavy Gases Interface

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Numerical Study on Turbulence mixing of Planar Shock Acceler...

Energy management strategy that optimizes battery degradation for electric vehicles with hybrid energy storage system

2016海峡两岸流体力学研讨会

作者： Wei-Gang Zeng jian-hua pan Yu-Tao Sun Yu-Xin Ren School of Aerospace Engineering Tsinghua University Beijing Institute of Applied Physics and Computational Mathematics

The interaction of a planar shock wave with a sulfur hexafluoride(SF6) triangular surrounded by air is numerically studied based on high resolution finite volume method with Minimum Dispersion and Controllable Dissipation(MDCD) reconstruction. The vortex dynamics of Richtmyer-Meshkov instability(RMI) and the turbulent mixing during the evolution of Kelvin–Helmholtz instability(KHI) are discussed. The typical processes of shock driven interfacial instability until turbulent mixing transition are identified in this study. The spectral analysis of turbulent kinetic energy(TKE) shows that the merging process of the primary Kelvin–Helmholtz billows will extend the region with a broadband spectrum of motion, and consequently, enhance the overall mixing of fluids. Both analysis of the TKE spectra and the variable-density energy spectra manifests the inertial range by the latter stages. Additionally, length scale analysis shows that the Liepmann-Taylor scale is decoupled from the inner-viscous scale during the evolution, which implies that there is a turbulent mixing transition. A further analysis of energy transfer in Fourier space indicates the nonlinear transfer term is of significance while the physical dissipation term is negligible. The detailed analysis for the nonlinear transfer term implies that the quadratic and pressure components are dominant terms, but the dilatation component is of less significance due to the weak compressibility. It is observed that the quadratic and pressure components tend to cancel each other in most part of the mixing region. The underlining mechanism is studied and its relation with the transition to turbulence is identified.

关键词： MDCD Richtmyer-Meshkov instability Kelvin–Helmholtz instability Length scale Turbulent mixing

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Science China Technological Sciences 2025年

作者： jian WANG Chaofeng pan Zhongxing LI School of Automotive and Traffic Engineering Jiangsu University Automotive Engineering Research Institute Jiangsu University

The short life of electric vehicle (EV) batteries is an important factor limiting the popularization of EVs. A hybrid energy storage system (HESS) for EVs combines Li-ion batteries with supercapacitors, so that the supercapacitor shares the peak power during the starting and braking, effectively solving the problem of irreversible capacity degradation of Li-ion batteries. Herein, an energy management strategy for HESS was designed based on battery degradation to extend the service life of the EV battery. First, to obtain accurate battery degradation characteristics, a cycling charge–discharge test was *** this test, the effects of discharge rate and state of charge on battery degradation rate were determined, and the battery degradation model was constructed. Based on the working map of the motor obtained through the bench test, a data-based model of the power system was constructed to accurately characterize the energy consumption of the EV under different operating conditions. Second, rule-based and optimization-based energy management strategies that consider battery degradation were designed using the fuzzy algorithm and dynamic programming (DP) algorithm. The effectiveness of the devised control strategies was assessed using the model-in-the-loop and hardware-in-the-loop test platforms. The fuzzy control strategy had a simple structure and could be rapidly calculated but showed worse performance than the DP-based strategy in terms of battery degradation. The DP-based energy management strategy resulted in 16.68%lower capacity degradation than the fuzzy strategy.

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Nonlinear dynamics of electroencephalography study in schizophrenic patients

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Chinese Medical Journal 2013年第15期126卷 2886-2889页

作者： CHEN Xing-shi XU Yi-feng TANG Yun-xiang FANG Yi-ru ZHANG Chen ZHANG Ming-dao LOU Fei-ying LIANG jian-hua CHEN Chong pan Xiao YAN Jin CUI Yi Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Dept Electrophysiol Shanghai 200030 Peoples R China Shanghai Jiao Tong Univ Shanghai Mental Hlth Ctr Dept Psychiat Shanghai 200030 Peoples R China PLA Mil Med Univ 2 Fac Psychol & Mental Hlth Shanghai 200433 Peoples R China

Background Few characteristic changes of linear electroencephalograph （EEG） have been reported in schizophrenia. The aim of the present study was to investigate the changes in temporal-spatial dimensional properties of EEG under different cognitive tasks in patients with schizophrenia. Methods EEG was recorded by using EEG-1518K system and mapping system （Nihon Kohden Tomioka Corporation, Japan） in 45 schizophrenic patients and 47 healthy adults （normal control, NC） under five states： eyes c^osed, eyes open, mental arithmetic test with eyes closed, memory test with eyes open, and number cancellation test. Correlation dimension （D2） and point-wise correlation dimension （PD2） were calculated for all EEG analyses. Results （1） There were no significant differences of D2 and PD2 between NC and schizophrenic patients under states of eyes open and closed. （2） Compared with NC, schizophrenic patients showed decreased performance of D2 in mental arithmetic test with eyes closed and number cancellation test （mental arithmetic test with eyes closed： Nc 5.9±0.6, Sch 3.0＋0.8; number cancellation test： Nc 6.0±0.6, Sch 4.4±0.7; P 〈0.05 or P 〈0.01）. （3） Schizophrenic patients also showed decrease performance of PD2 in mental arithmetic test with eyes closed, memory test with eyes open, and number cancellation test （mental arithmetic test with eyes closed： Nc 6.9±0.7, Sch 4.0±0.8; memory test with eyes open： Nc 6.6±0.8, Sch 5.0±0.9; number cancellation test： Nc 7.1±0.7, Sch 4.8±0.9; P 〈0.05 or P 〈0.01）. Conclusions Nonlinear dynamic analysis provided a new approach in clinical investigation of EEG signals. It was helpful to further understand the cerebral mechanism in schizophrenic cognitive process.

关键词： schizophrenia electroencephalography nonlinear dynamics cognition

Deciphering the role of mtH2O2 in hepatic ischemia-reperfusion injury mechanisms with low-background super-resolution fluorogenic probe

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Science China Chemistry 2025年第01期 297-307页

作者： Bin Fang Limin Wang Haoqin Li Jiaxin Zhang Yang Ding pan pan Li Bo Peng hua Bai Lin Li Frontiers Science Center for Flexible Electronics Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials &Engineering Northwestern Polytechnical University Institute of Flexible Electronics (IFE Future Technologies) Xiamen University

Hepatic ischemia-reperfusion injury（HIRI） is characterized by mitochondrial dysfunction and oxidative stress. Monitoring mitochondrial hydrogen peroxide（mtH2O2） levels in real-time through super-resolution imaging is crucial for elucidating its distribution in live cells and its mechanism of action during HIRI. However, low-background fluorogenic probes have been overlooked in the context of super-resolution imaging. In this study, we developed a low-background fluorogenic probe（MitoWG） with the potential for super-resolution morphology-correlated mitochondrial identification to track the fluctuates of mtH2O2in HIRI. Activation of the desirable fluorescence properties of the probe by mtH2O2was confirmed using structural illumination microscopy（SIM）, enabling high-quality mitochondrial imaging with exceptional specificity and *** in mtH2O2levels were successfully observed in both cellular and rat models of HIRI. Furthermore, we associated the decline in mitochondrial redox homeostasis with accelerated mtH2O2production during HIRI, which triggered mitophagy deficiency and led to cell death. In conclusion, Mito-WG possesses excellent photophysical and low-background properties for SIM imaging, making it a promising tool for mtH2O2tracking in HIRI research and clinical diagnosis.

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重组人EGF-IL-18融合蛋白的表达纯化及复性

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细胞生物学杂志 2006年第5期28卷 711-716页

作者：潘建华彭颖郑昭暻吕建新温州医学院细胞与分子医学研究所浙江省医学遗传学重点实验室温州325035

融合基因EGF-IL-18与表达载体pET32a(+)连接构建融合型原核表达质粒pET32a(+)-EGF-IL-18。该基因在***(DE3)中获得高效表达,SDS-PAGE分析表明表达产物大部分以包涵体形式存在。以2mol/L尿素和1%TritonX-100对包涵体进行反复洗涤后,利用... 详细信息

融合基因EGF-IL-18与表达载体pET32a(+)连接构建融合型原核表达质粒pET32a(+)-EGF-IL-18。该基因在***(DE3)中获得高效表达,SDS-PAGE分析表明表达产物大部分以包涵体形式存在。以2mol/L尿素和1%TritonX-100对包涵体进行反复洗涤后,利用离子交换柱层析对包涵体进行柱上复性,结果表明离子交换层析柱上复性不仅能够获得可溶性的EGF-IL-18融合蛋白,而且产物同时得到纯化,纯度大于90%。复性的EGF-IL-18经分子筛进一步纯化后,体外实验证明具有促进人外周血单个核细胞(PBMC)IFN-g基因表达的能力。该方法简单、高效,为进一步开展EGF-IL-18的动物实验及其大量纯化制备打下基础。

关键词： EGF-IL-18融合蛋白包涵体离子交换柱层析柱上复性

Bioactive materials from berberine-treated human bone marrow mesenchymal stem cells accelerate tooth extraction socket healing through the jaw vascular unit

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Science China Life Sciences 2025年

作者： Ruyu Wang Tianxiao Wang Ziyu Chen jiandong jiang Yifei Du hua Yuan Yongchu pan Yuli Wang Department of Oral and Maxillofacial Surgery The Affiliated Stomatological Hospital of Nanjing Medical University State Key Laboratory Cultivation Base of Research Prevention and Treatment for Oral Diseases Jiangsu Province Engineering Research Centre of Stomatological Translational Medicine Nanjing Medical University Department of Stomatology Chongzhou People's Hospital Medical Basic Research Innovation Centre for Cardiovascular and Cerebrovascular Diseases Ministry of Education International Joint Laboratory for Drug Target of Critical Illnesses School of PharmacyNanjing Medical University Institute of Medicinal Biotechnology Chinese Academy of Medical Sciences & Peking Union Medical College Department of Orthodontic The Affiliated Stomatological Hospital of Nanjing Medical University State Key Laboratory Cultivation Base of Research Prevention and Treatment for Oral Diseases Jiangsu Province Engineering Research Centre of Stomatological Translational Medicine Nanjing Medical University

Delayed tooth extraction socket(TES) healing can cause failure of subsequent oral implantation and increase socioeconomic burden on patients. Excessive amounts of M1 macrophages, apoptotic neutrophils(ANs), and neutrophil extracellular traps(NETs) impair alveolar bone regeneration during TES healing. In the present study, we first discovered that conditioned medium(CM) collected from berberine-treated human bone marrow mesenchymal stem cells(BBR-HB-CM) accelerated TES healing. BBR-HB-CM contained bioactive materials that promoted the polarization of macrophages from M1 to M2, impeded the formation of ANs and NETs, and modulated M2 macrophage efferocytosis in vivo and in vitro. Mechanistically, BBR-HB-CM promoted bone formation by inhibiting macrophage-myofibroblast transition and reprogrammed macrophage polarization through p85/AKT/mTOR pathway-dependent autophagy. The 3-methyladenine abolished the therapeutic effects of BBR-HB-CM. Further studies revealed that BBR-HB-CM accelerated TES healing in rats with type 2 diabetes mellitus. Overall, our results demonstrated that BBR-HB-CM had high potential to promote rapid TES healing.

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