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论公司法规制国家出资公司的口径与路径

中南大学学报（社会科学版） 2024年第3期30卷 66-76页

作者：李建伟何健中国政法大学民商经济法学院北京100088

新修订的公司法增加了第七章“国家出资公司组织机构的特别规定”,实现公司法对国家出资公司的规制体例编排“从节到章”、条款数量“从少到多”以及适用范围“从国有独资到国家出资”的重要进步,相当程度上克服了原公司法中存在的规制... 详细信息

新修订的公司法增加了第七章“国家出资公司组织机构的特别规定”,实现公司法对国家出资公司的规制体例编排“从节到章”、条款数量“从少到多”以及适用范围“从国有独资到国家出资”的重要进步,相当程度上克服了原公司法中存在的规制理念陈旧、口径局限、路径紊乱等缺陷。但新公司法仍存在规制口径模糊、组织规范制度供给不足等痼疾,需要进一步校准国家出资公司的规制口径,将国有独资公司的全资子公司纳入其中,保证规制逻辑的周延性;继续改进规制路径与立法技术,通过引致技术简化关联部门法的重复性规定,增加具有制度特色的治理规则供给,包括完善党组织条款,细化外部董事条款,鼓励并引导国有控股公司章程设置赋权性的差异化治理条款,以提升公司法的适应性品格。

关键词：国家出资公司规制口径规制路径公司法

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Biodegradation of pendimethalin by Bacillus subtilis Y3

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Journal of Environmental Sciences 2016年第3期28卷 121-127页

作者： Haiyan Ni Li Yao Na Li Qin Cao Chen Dai Jun Zhang Qin he jian he Key Laboratory of Microbiological Engineering of Agricultural Environment Ministry of AgricultureLife Sciences College of Nanjing AgriculturalUniuersityNanjing 210095China China national Center.for Biotechnology Development Beijing 100039China College of Life Sciences Laboratory centre of Life SciencesNanjing Agricultural UniversityNanjing 210095China Key Laboratory of Plant Nutrition and Fertilization in Low-Middle Reaches of the Yangtze River Ministry of AgricultureCollege of Resourcesand Environmental SciencesNanjing Agricultural UniversityNanjing 210095China

A bacterium strain Y3,capable of efficiently degrading pendimethalin,was isolated from activated sludge and identified as Bacillus subtilis according to its phenotypic features and 16 S rRNA phylogenetic analysis.This strain could grow on pendimethalin as a sole carbon source and degrade 99.5%of 100 mg/L pendimethalin within 2.5 days in batch liquid culture,demonstrating a greater efficiency than any other reported strains.Three metabolic products,6-aminopendimethalin,5-amino-2-methyl-3-nitroso-4-（pentan-3-ylamino） benzoic acid,and 8-amino-2-ethyl-5-（hydroxymethyl）-1,2-dihydroquinoxaline-6-carboxylic acid,were identified by HPLC-MS/MS,and a new microbial degradation pathway was proposed.A nitroreductase catalyzing nitroreduction of pendimethalin to 6-aminopendimethalin was detected in the cell lysate of strain Y3.The cofactor was nicotinamide adenine dinucleotide phosphate（NADPH） or more preferably nicotinamide adenine dinucleotide（NADH）.The optimal temperature and pH for the nitroreductase were 30℃ and 7.5,respectively.Hg^（2＋）,Ni^（2＋）,Pb^（2＋）,Co^（2＋）,Mn^（2＋） Cu^（2＋）,Ag~＋,and EDTA severely inhibited the nitroreductase activity,whereas Fe^（2＋）,Mg^（2＋）,and Ca^（2＋） enhanced it.This study provides an efficient pendimethalin-degrading microorganism and broadens the knowledge of the microbial degradation pathway of pendimethalin.

关键词： Pendimethalin Biodegradation Bacillus sp.Y3 Metabolic pathway Nitroreductase

Massive bleeding from a gastric artery pseudoaneurysm in hepatocellular carcinoma treated with atezolizumab plus bevacizumab: A case report

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World Journal of Gastrointestinal Surgery 2023年第6期15卷 1232-1239页

作者： Fu-Wen Pang Bin Chen De-Ti Peng jian he Wei-Cheng Zhao Tuan-Tuan Chen Zong-Gui Xie Hai-Hui Deng Department of Interventional Radiology Shenzhen Traditional Chinese Medicine HospitalShenzhen 518033Guangdong ProvinceChina Department of hepatology Shenzhen Traditional Chinese Medicine HospitalShenzhen 518033Guangdong ProvinceChina

BACKGROUND The combination of atezolizumab(ATZ)and bevacizumab(BVZ)was approved as first-line systemic therapy for advanced hepatocellular carcinoma(HCC)owing to its superior rates of response and patient survival.However,ATZ+BVZ is associated with increased risk of upper gastrointestinal(GI)bleeding,including arterial bleeding,which is rare and potentially fatal.We present a case of massive upper GI bleeding from a gastric pseudoaneurysm in a patient with advanced HCC who had been treated with ATZ+BVZ.CASE SUMMARY A 67-year-old man presented with severe upper GI bleeding after atezolizumab(ATZ)+bevacizumab(BVZ)therapy for HCC.Endoscopy failed to detect the bleeding site.Digital subtraction angiography revealed a gastric artery pseudoaneurysm and contrast extravasation from the inferior splenic artery and a branch of the left gastric artery.Successful hemostasis was achieved with embolization.CONCLUSION HCC patients who have been treated with ATZ+BVZ should be followed for 3 to 6 mo to monitor for development of massive GI bleeding.Diagnosis may require angiography.Embolization is an effective treatment.

关键词： Atezolizumab Bevacizumab hepatocellular carcinoma Gastric artery pseudoaneurysm Gastrointestinal bleeding Case report

锆钇废料制备氧化钇和磷酸锆吸附剂及其性能评价

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无机盐工业 2024年第3期56卷 116-124页

作者：徐梦瑶张欣何琨鹏何坚蒋炜中国石油化工股份有限公司西北油田分公司新疆乌鲁木齐830011 四川大学化学工程学院四川成都610065

钇稳定氧化锆是一种性能优异的材料,在其生产和使用过程中会产生大量切削边角料等固体废物,对其进行回收处理,有助于环境保护和资源有效利用。由于废料性质稳定,将其回收和转化为有价值的产品成为资源有效利用的关键。研究提出将锆钇废... 详细信息

钇稳定氧化锆是一种性能优异的材料,在其生产和使用过程中会产生大量切削边角料等固体废物,对其进行回收处理,有助于环境保护和资源有效利用。由于废料性质稳定,将其回收和转化为有价值的产品成为资源有效利用的关键。研究提出将锆钇废料转为氢氧化锆和草酸钇中间体,并进一步转化为磷酸锆和氧化钇吸附剂,增加锆钇废料资源化新路线。该合成路线以乙醇为分散助剂,氢氧化锆、草酸和磷酸二氢钠按物质的量为1∶2∶2比例混合,373 K反应6 h制得层状磷酸锆对钾离子的吸附容量为151.6 mg/g,可将模拟高钾血清中的钾浓度降至人体正常水平(4.51 mmol/L)且不损失过多的钠离子。以草酸钇氨水合物煅烧得到的氧化钇,可作为硫酸根的高效吸附剂。研究结果显示,在1073 K煅烧草酸钇氨水合物得到的氧化钇,在添加量为10 g/L、强酸性溶液的条件下,可保持98.6%的硫酸根去除率。硫酸根离子被氧化钇吸附的过程遵循Langmuir等温吸附模型,属于单分子层吸附,其准二级动力学常数为2.03×10^(-3) g/(min·mg),属于化学吸附。

关键词：锆钇废料磷酸锆氧化钇吸附

Phylogenomic conflict analyses in the apple genus Malus s.l.reveal widespread hybridization and allopolyploidy driving diversification,with insights into the complex biogeographic history in the Northern hemisphere

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Journal of Integrative Plant Biology 2022年第5期64卷 1020-1043页

作者： Bin-Bin Liu Chen Ren Myounghai Kwak Richard GJHodel Chao Xu jian he Wen-Bin Zhou Chien-Hsun Huang Hong Ma Guan-Ze Qian De-Yuan Hong Jun Wen State Key Laboratory of Systematic and Evolutionary Botany Institute of Botanythe Chinese Academy of SciencesBeijing 100093China Department of Botany National Museum of Natural HistorySmithsonian InstitutionPO Box 37012Washington 20013–7012DCUSA Key Laboratory of Plant Resources Conservation and Sustainable Utilization South China Botanical GardenThe Chinese Academy of SciencesGuangzhou 510650China Guangdong Provincial Key Laboratory of Applied Botany South China Botanical GardenThe Chinese Academy of SciencesGuangzhou 510650China National Institute of Biological Resources Incheon 22689South Korea School of Ecology and Nature Conservation Beijing Forestry UniversityBeijing 100083China Department of Plant and Microbial Biology North Carolina State UniversityRaleigh 27965NCUSA State Key Laboratory of Genetic Engineering and Collaborative Innovation Center of Genetics and Development Ministry of Education Key Laboratory of Biodiversity and Ecological EngineeringInstitute of Plant BiologyCenter of Evolutionary BiologySchool of Life SciencesFudan UniversityShanghai 200433China Department of Biology Huck Institutes of the Life SciencesPennsylvania State University510D Mueller LaboratoryUniversity ParkPennsylvania 16802USA College of Life Sciences Liaocheng UniversityLiaocheng 252059China

Phylogenomic evidence from an increasing number of studies has demonstrated that different data sets and analytical approaches often reconstruct strongly supported but conflicting relationships.In this study,785 single-copy nuclear genes and 75 complete plastomes were used to infer the phylogenetic relationships and estimate the historical biogeography of the apple genus Malus sensu lato,an economically important lineage disjunctly distributed in the Northern hemisphere and involved in known and suspected hybridization and allopolyploidy events.The nuclear phylogeny recovered the monophyly of Malus s.l.(including Docynia);however,the genus was supported to be biphyletic in the plastid phylogeny.An ancient chloroplast capture event in the Eocene in western North America best explains the cytonuclear discordance.Our conflict analysis demonstrated that ILS,hybridization,and allopolyploidy could explain the widespread nuclear gene tree discordance.One deep hybridization event(Malus doumeri)and one recent event(Malus coronaria)were detected in Malus s.l.Furthermore,our historical biogeographic analysis integrating living and fossil data supported a widespread East Asianwestern North American origin of Malus s.***.in the Eocene,followed by several extinction and dispersal events in the Northern hemisphere.We also propose a general workflow for assessing phylogenomic discordance and biogeographic analysis using deep genome skimming data sets.

关键词： deep genome skimming genomic discordance historical biogeography massive extinction reticulate evolution single-copy nuclear genes

Pseudo-concentrated electrolytes for lithium metal batteries

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eScience 2022年第5期2卷 557-565页

作者： Huaping Wang jiandong Liu jian he Shihan Qi Mingguang Wu Fang Li Junda Huang Yun Huang jianmin Ma School of Physics and Electronics Hunan UniversityChangsha410082China

Lithium metal batteries suffer from short lifespans and low Coulombic efficiency (CE) due to the high reactivity of Li and the poor stability of the solid electrolyte interphase (SEI). herein, we propose the concept of a pseudo-concentrated electrolyte (PCE) induced by an electron-deficient additive (4-pyridylboronic acid;4-PBA) to form a robust, LiF-rich SEI, thus addressing the above issues. Molecular dynamics simulations confirm that 4-PBA can increase the coordination number of PF6^(-) anions in the Li+ solvation sheath to achieve pseudo-concentrated LiPF6 in the electrolyte. Moreover, the 4-PBA can scavenge harmful PF5 decomposed from LiPF6 to stabilize the LiF-rich SEI. The resulting robust LiF-rich SEI promotes Li growth along the SEI/Li interface and represses the growth of Li dendrites. Thus, excellent performance is achieved, with a high CE of 97.1% for a Li||Cu cell at 1.0 mA cm^(−2), and over 950 cycles at 0.5 mA cm^(−2) for Li||Li symmetric cells with 1.0 wt% 4-PBA electrolyte. Meanwhile, the resulting stable boron-containing cathode electrolyte interphase enables Li||LiNi0·6Co0·2Mn0·2O_(2) (NCM622) cells to achieve excellent stability, with a capacity retention of 86.9% after 200 cycles.

关键词： Lithium metal batteries Pseudo-concentrated electrolyte Solid electrolyte interphase Solvation structure 4-Pyridylboronic acid

Targeting neuropilin-1 interactions is a promising anti-tumor strategy

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Chinese Medical Journal 2021年第5期134卷 508-517页

作者： Shao-Dan Liu Li-Ping Zhong jian he Yong-Xiang Zhao National Center for International Research of Bio-targeting Theranostics Guangxi Key Laboratory of Bio-targeting TheranosticsCollaborative Innovation Center for Targeting Tumor Diagnosis and TherapyGuangxi Medical UniversityNanningGuangxi 530021China

Neuropilins(NRP1 and NRP2)are multifunctional receptor proteins that are involved in nerve,blood vessel,and tumor development.NRP1 was first found to be expressed in neurons,but subsequent studies have demonstrated its surface expression in cells from the endothelium and lymph nodes.NRP1 has been demonstrated to be involved in the occurrence and development of a variety of cancers.NRP1 interacts with various cytokines,such as vascular endothelial growth factor family and its receptor and transforming growth factor p i and its receptor,to affect tumor angiogenesis,tumor proliferation,and migration.In addition,NRP1+regulatory T cells(Tregs)play an inhibitory role in tumor immunity.High numbers of NRP1+Tregs were associated with cancer prognosis.Targeting NRP1 has shown promise,and antagonists against NRP1 have had therapeutic efficacy in preliminary clinical studies.NRP1 treatment modalities using nanomaterials,targeted drugs,oncolytic viruses,and radio-chemotherapy have gradually been developed.hence,we reviewed the use of NRP1 in the context of tumorigenesis,progression,and treatment.

关键词： Neuropilin-1 Anti-tumor Immunotherapy Tumor targeting

Bluetooth-based authentication system for ambient intelligence

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2008年第6期9卷 770-775页

作者： jian he Hui LI Yong ZHANG Zhang-qin HUANG School of Software Engineering Beo＇ing University of Technology Beo＇ing 100022 China College of Computer Science Beijing University of Technology Beijing 100022 China College of Electronic Information and Automation Tianjin University of Science and Technology Tianjin 300222 China

According to the requirement of natural human-computer interaction for Ambient Intelligence (AmI), a Bluetooth- based authentication technique is provided. An authentication network combining advantages of Bluetooth ad hoc network with the Ethernet is introduced first in detail. Then we propose a Bluetooth badge for storing the user's identification information. Finally, the authentication system based on Bluetooth badge and authentication network is introduced. It is demonstrated ex- perimentally that the Bluetooth-based authentication technique can authenticate the user automatically.

关键词：智能系统鉴定系统蓝牙人-机交互作用

Effects of rare earth oxides on microstructures and thermo-physical properties of hafnia ceramics

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Journal of Materials Science & Technology 2021年第13期72卷 144-153页

作者： Chun Li Chaolong Ren Yue Ma jian he Hongbo Guo School of Materials Science and Engineering Beihang UniversityBeijing100191China Key Laboratory of High-temperature Structural Materials&Coatings Technology(Ministry of Industry and Information Technology) Beihang UniversityBeijing100191China

Rare earth oxides doped hafnia ceramics,with a formula of Hf0.76LnxY0.24-xO1.88(Ln=Gd,Yb,Gd+Yb or La+Yb),were prepared by solid state sintering at 1500℃.The effects of the rare earth oxides on the microstructures,sintering resistance,and thermo-physical properties of the doped hafnia ceramics were investigated.Results show that the Gd-Y,Yb-Y or Gd-Yb-Y co-doped hafnia ceramics remain the same defect fluorite(F)structure,while the La-Yb-Y co-doped hafnia revealing coexistence of pyrochlore(P)and fluorite structures.Yb-Y co-doped samples exhibited much better sintering resistance compared with Gd-Y and Gd-Yb-Y co-doped samples.The coexistence of P and F phases is beneficial to improved sintering capability.The thermal conductivities of the Gd-Y,Yb-Y and Gd-Yb-Y doped samples are relatively lower(1.4-1.7 W m^(-1)K^(-1)at 1200℃),but for the La-Yb-Y co-doped samples,the thermal conductivity increases dramatically with temperature due to increased thermal radiation at high-temperature.The average thermal expansion coefficients(TECs)of the Gd-Y,Yb-Y and Gd-Yb-Y co-doped samples are as high as10.3×10^(-6)K^(-1) in temperature range between 200-1200℃.

关键词： Rare earth oxides multi-doped hafnia Fluorite Pyrochlore Sintering resistance Thermo-physical properties