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中国宏观经济波动中的结构变迁特征

探索 2005年第4期 89-93页

作者：陈仲常简钟丹重庆大学贸易及行政学院重庆400044

中国经济在近20年的时间内,保持了快速的发展,但是也经历了不小的波动,大致分为三个阶段:80年代至90年代中期经济波动的特征是短缺经济中的经济过热,1996至2000年是通缩期中的生产过剩,2001年至今是新的市场需求引发的经济过热。本文通... 详细信息

中国经济在近20年的时间内,保持了快速的发展,但是也经历了不小的波动,大致分为三个阶段:80年代至90年代中期经济波动的特征是短缺经济中的经济过热,1996至2000年是通缩期中的生产过剩,2001年至今是新的市场需求引发的经济过热。本文通过产业的影响力系数和感应度系数分析对中国经济波动的结构变迁特征做出了新的解释。

关键词：宏观经济波动结构变迁影响力系数感应度系数

用PAMPA和MDCK模型研究川芎嗪的跨膜吸收机制

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浙江工业大学学报 2010年第6期38卷 616-619页

作者：葛建丹陈媚宋必卫浙江工业大学药学院浙江杭州310032

利用PAMPA(Parallel artificial membrane permeation assay)和狗肾小管上皮(MDCK)细胞模型探讨盐酸川芎嗪(TMPH)的跨膜吸收过程及其机制.用lecithin/n-dodecane溶液在Multi-Screen-IP板上建立PAMPA模型,将MDCK细胞以5×104个/cm2接种到Millicell-CM CulturePlate Inserts(Millicell CPI)上培养至细胞生长融合成完整单层,然后测定TMPH在PAMPA和MDCK单层细胞模型上的跨膜透过情况,计算累积透过量.实验结果表明:TMPH在PAMPA上有一定的被动扩散吸收,在MDCK模型上除存在一定量的被动扩散转运外,还有其它形式的转运机制如依赖于转运蛋白的易化扩散或主动转运等参与.

关键词： PAMPA MDCK细胞模型盐酸川芎嗪

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有机阴离子转运蛋白介导绿原酸肾小管分泌

浙江工业大学学报 2010年第3期9卷 322-325,337页

作者：陈媚葛建丹宋必卫浙江工业大学药学院浙江杭州310032

利用狗肾近端小管上皮(MDCK)细胞单层模型比较丙磺舒、牛磺酸、青霉素钠等不同药物转运蛋白底物对双黄连口服液中绿原酸分泌的影响.MDCK细胞以1.5×104个细胞/孔接种于Milli-cell-CMculture plate inserts上培养,定期观察细胞形态,测定... 详细信息

利用狗肾近端小管上皮(MDCK)细胞单层模型比较丙磺舒、牛磺酸、青霉素钠等不同药物转运蛋白底物对双黄连口服液中绿原酸分泌的影响.MDCK细胞以1.5×104个细胞/孔接种于Milli-cell-CMculture plate inserts上培养,定期观察细胞形态,测定跨膜电阻值,待细胞单层达到一定致密程度后进行分泌实验.用M2e酶标仪测定单用双黄连口服液和合用丙磺舒、牛磺酸、青霉素钠时各组双黄连口服液中绿原酸的跨细胞转运情况,计算累积分泌量.实验结果表明,合用不同转运蛋白底物后,双黄连口服液中绿原酸的分泌量均明显降低.可见绿原酸经肾小管上皮细胞的分泌过程是一可饱和过程,有机阴离子转运蛋白部分参与绿原酸的分泌机制.

关键词： MDCK细胞模型绿原酸有机阴离子转运蛋白

Protective effects of CE on oxidative stress induced aging mice

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Protective effects of CE on oxidative stress induced aging m...

Epidemiological survey of cystic echinococcosis in southwest China:From the Qinghai-Tibet plateau to the area of Yunnan

The International Meeting of the Society for Free Radical Research(SFRR)-Asia & the Third International Symposium on Natural Antioxidants-Molecular Mechanisms and Health Effects(ISNA)

作者： jian-jun Zhang dan Zhang Institute of materia medica, Chinese academy of medical sciences & Peking union of medical college, 1 Xiannongtan Street, Beijing 100050, China

AIM: To study the anti-aging effects of CE, an effective extract isolated from a Tibetan medicine, on senescent mice induced by D-galactose and NaNO2. METHODS: The aging mice were induced by repeated injection of D-galactose (120 mg/kg, i.p.) and NaNO2 (90 mg/kg, i.p.) for 60 days. CE (2.5, 5, 10 mg/kg, p.o.) were administrated from the 47 d. Water maze and step-down tests were performed to evaluate the learning and memory function in

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World Journal of Hepatology 2024年第2期16卷 229-240页

作者： Jin-Rong Zi dan Xiao Jia Peng Fang-Wei Wu jian-Xiong Li Xin-Liu Yan Zheng-Qing Wang Xuan Cai Qian Xu Ben-Fu Li Ya-Ming Yang Yunnan Provincial Center of Malaria Research Yunnan Institute of Parasitic DiseasesPuer 665000Yunnan ProvinceChina Yunnan Institute of Parasitic Diseases Yunnan Institute of Parasitic DiseasesPuer 665000Yunnan ProvinceChina Tibet Center for Disease Control and Prevention Tibet Center for Disease Control and PreventionLhasa 85000Tibet Autonomous RegionChina Yunnan Provincial Center of Malaria Research Yunnan Institute of Parasitic DiseasesPuer 655000Yunnan ProvinceChina

BACKGROUND Echinococcosis is prevalent in 9 provinces in Western and Northern *** epidemiological survey of echinococcosis in 2012 and 2016 showed cases of echinococcosis in Yunnan *** To understand the spatial distribution and epidemiological characteristics of echinococcosis in Yunnan for the prevention and control of echinococcosis and to reduce the risk of infection in Yunnan *** Based on the China Information System for Disease Control and Prevention(CISDCP),echinococcosis cases reported from 36 hospitals and 34 Centers for Disease Control were investigated and epidemiologically analyzed from 2021 to *** exclusion criteria included suspected cases,same case only counted once and cases not from Yunnan.A total of 705 cases were investigated,of which 397 cases were suitable for statistical *** these 397 cases,epidemiological investigation was tracked in 187 *** data were inputted using double entry in the Excel database,with error correction by double-entry *** data on echinococcosis cases in Yunnan Province were analyzed by ArcGIS 10.1 software to generate a density map of echinococcosis *** statistical analyses were conducted using SPSS 17.0,including the chi-square test,linear regression test and logistic univariate and multivariate regression *** A total of 397 cases were found in 89 counties in Yunnan *** number of cases in the top three prefectures were Dali(38.1%),Diqing(10.1%),and Kunming(8.3%),and the top five counties were jianchuan(9.1%),Shangri La(8.3%),Eryuan(7.6%),Heqing(6.9%),and Dali Districts(5.0%).There were significant differences between the different *** case reporting rate by CISDCP(33.8%)was low;the first case was reported by CISDCP in 2002,and the highest number of cases was 50(2017).Confirmed and clinical cases accounted for 62.5%and 37.5%,***,90.9%of the cases of hydatid disease were reported by the hospital system,and only 9

关键词： Echinococcosis Cases Epidemiological analysis Yunnan province