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China CDC weekly 2023年第35期5卷 767-772,I0001页

作者： Yuan Li Suhong Gao jiamei wang Hang An Le Zhang Yali Zhang Xiaohong Liu Zhiwen Li Institute of Reproductive and Child Health Peking University/Key Laboratory of Reproductive HealthNational Health Commission of the People’s Republic of ChinaBeijingChina Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Department of Child Health Beijing Haidian Maternal and Child Health HospitalBeijingChina Department of Gynaecology and Obstetrics Beijing Haidian Maternal and Child Health HospitalBeijingChina

Summary What is already known about this topic?Interpregnancy intervals(IPIs)that are either excessively long or short have been linked with an elevated risk of adverse perinatal ***,no pertinent guidelines have been established in China to provide clear direction with regard to optimal *** is added by this report?A brief interpregnancy interval may elevate the risk of miscarriage,postpartum hemorrhage,and fetal distress among expectant *** are the implications for public health practice?

关键词： pregnancy elevated distress

AVAPS-AE模式的无创通气对AECOPD合并OSA患者PSG参数、ESS评分及舒适度的影响

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昆明医科大学学报 2024年第4期45卷 105-112页

作者：田茂良韩博学王佳梅宗政邓治平自贡市第一人民医院呼吸与危重症医学科四川自贡643000 火箭军总医院呼吸科北京100000

目的探讨平均容积保证压力支持-自动呼气压(AVAPS-AE)模式的无创通气对慢性阻塞性肺疾病急性加重期(AECOPD)合并阻塞性睡眠呼吸暂停(OSA)患者多道睡眠监测(PSG)参数、Epworth嗜睡量表(ESS)评分及舒适度的影响。方法选取2020年1月至2022... 详细信息

目的探讨平均容积保证压力支持-自动呼气压(AVAPS-AE)模式的无创通气对慢性阻塞性肺疾病急性加重期(AECOPD)合并阻塞性睡眠呼吸暂停(OSA)患者多道睡眠监测(PSG)参数、Epworth嗜睡量表(ESS)评分及舒适度的影响。方法选取2020年1月至2022年10月自贡市第一人民医院75例AECOPD合并OSA患者,随机分为3组,各25例,均行无创通气治疗,对照A组予以AVAPS模式,对照B组予以S/T模式,观察组予以AVAPS-AE模式。比较3组治疗前、治疗24 h、48 h及72 h血气分析指标[动脉氧分压(PaO_(2))、动脉血酸碱度(pH)、动脉二氧化碳分压(PaCO_(2))]、PSG参数[微觉醒指数(MAI)、呼吸暂停低通气指数(AHI)、最低脉搏氧饱和度(miniSpO_(2))、睡眠效率(TST/TRT)]、颏舌肌肌电值(GGEMG)各变量[清醒期及睡眠NREM期张力性、峰值、时相性GGEMG]、人机对抗发生率、48 h插管率、ESS、Brog、视觉模拟量表(VAS)及健康相关生存质量(HRQL)评分。结果治疗24 h、48 h及72 h PaO_(2)组间比较:观察组>对照A组>对照B组(P对照A组>对照B组(P0.05);ESS、Brog、VAS评分组间比较:观察组对照A组>对照B组(P<0.05)。结论AVAPS-AE模式的无创通气用于AECOPD合并OSA有利于改善患者睡眠,减少日间嗜睡,缓解呼吸困难,提高呼吸舒适度及生存质量。

关键词：无创通气 OSA AECOPD AVAPS-AE PSG ESS

基于振动传递率的层合板局部脱层损伤识别研究

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西华大学学报（自然科学版） 2024年第5期43卷 30-35,130页

作者：卢召红彭郑飞殷兆龙姚晗曦王佳美东北石油大学土木建筑工程学院黑龙江大庆163318 大庆油田工程建设有限公司黑龙江大庆163453 大庆石油化工机械厂有限公司黑龙江大庆163714

为简单准确测出层合板结构的局部脱层损伤位置,提出了一种基于振动传递率函数稀疏化的局部脱层损伤识别方法。文章设计了含脱层GFRP层合板受迫振动的实验方案,并采集板面多点加速度响应数据,利用数据构建振动传递率函数图谱,选取局部稳... 详细信息

为简单准确测出层合板结构的局部脱层损伤位置,提出了一种基于振动传递率函数稀疏化的局部脱层损伤识别方法。文章设计了含脱层GFRP层合板受迫振动的实验方案,并采集板面多点加速度响应数据,利用数据构建振动传递率函数图谱,选取局部稳态频段利用L1范数稀疏化提出脱层损伤指标TD;分析不同脱层位置,不同脱层程度对脱层损伤指标TD的影响。结果表明,该损伤识别指标TD的分布与实际试件脱层损伤的分布吻合性好,利用此指标可进行层合板脱层位置和脱层损伤识别,具有很好的工程应用价值。

关键词：振动传递率函数加固层合板脱层损伤识别结构检测加固

人参茎叶中丙二酰基人参皂苷对APAP诱导的小鼠肝损伤的保护及作用机制

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中国食品添加剂 2024年第2期35卷 1-8页

作者：王佳美王东升李嘉星李泽文陆雅倩刘志吉林农业大学中药材学院长春130118

建立对乙酰氨基酚(APAP)诱导的小鼠肝损伤模型,研究人参茎叶中丙二酰基人参皂苷提取物(MGR)对小鼠急性肝损伤的保护作用,并探讨其潜在作用机制。小鼠随机分为空白组、APAP模型组、MGR高剂量和低剂量组,建立肝损伤模型并给药。检测小鼠... 详细信息

建立对乙酰氨基酚(APAP)诱导的小鼠肝损伤模型,研究人参茎叶中丙二酰基人参皂苷提取物(MGR)对小鼠急性肝损伤的保护作用,并探讨其潜在作用机制。小鼠随机分为空白组、APAP模型组、MGR高剂量和低剂量组,建立肝损伤模型并给药。检测小鼠血清中的丙氨酸转移酶(ALT)、天冬氨酸转移酶(AST)、白细胞介素-1β(IL-1β)、肿瘤坏死因子α(TNF-α)及肝组织中的丙二醛(MDA)和谷胱甘肽(GSH)水平,并通过切片观察病理学变化。与APAP组相比,MGR组中MGR降低了小鼠血清中的ALT、AST、IL-1β、TNF-α水平的升高,并抑制了MDA的升高和GSH的降低。蛋白印迹分析显示,MGR提高了小鼠p-PI3K、p-AKT和Bcl-2的表达,降低了小鼠Bax的表达。MGR对APAP诱导的小鼠急性肝损伤具有保护作用,其保护作用机制可能与炎症,氧化应激,细胞凋亡有关。

关键词：丙二酰基人参皂苷提取物对乙酰氨基酚肝损伤人参

Porous 3D carbon-based materials:An emerging platform for efficient hydrogen production

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Nano Research 2023年第1期16卷 127-145页

作者： Fangyi Li Jizhou Jiang jiamei wang Jing Zou Wei Sun Haitao wang Kun Xiang Pingxiu Wu Jyh-Ping Hsu School of Environmental Ecology and Biological Engineering School of Chemistry and Environmental EngineeringKey Laboratory of Green Chemical Engineering Process of Ministry of EducationEngineering Research Center of Phosphorus Resources Development and Utilization of Ministry of EducationWuhan Institute of TechnologyWuhan 430205China Semiconductor Electronic Special Gas of Hubei Engineering Research Center Jingzhou 434000China Department of Chemical Engineering “National Taiwan University”Taipei 10617

Due to their unique properties and uninterrupted breakthrough in a myriad of clean energy-related applications,carbon-based materials have received great ***,the low selectivity and poor conductivity are two primary difficulties of traditional carbon-based materials(zero-dimensional(0D)/one-dimensional(1D)/two-dimensional(2D)),enerating inefficient hydrogen production and impeding the future commercialization of carbon-based *** improve hydrogen production,attempts are made to enlarge the surface area of porous three-dimensional(3D)carbon-based materials,achieve uniform interconnected porous channels,and enhance their stability,especially under extreme *** this review,the structural advantages and performance improvements of porous carbon nanotubes(CNTs),g-C_(3)N_(4),covalent organic frameworks(COFs),metal-organic frameworks(MOFs),MXenes,and biomass-derived carbon-based materials are firstly summarized,followed by discussing the mechanisms involved and assessing the performance of the main hydrogen production *** include,for example,photo/electrocatalytic hydrogen production,release from methanolysis of sodium borohydride,methane decomposition,and *** role that the active sites of porous carbon-based materials play in promoting charge transport,and enhancing electrical conductivity and stability,in a hydrogen production process is *** current challenges and future directions are also discussed to provide guidelines for the development of next-generation high-efficiency hydrogen 3D porous carbon-based materials prospected.

关键词： porous three-dimensional(3D)carbon-based materials hydrogen production advanced synthesis

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氦气富集理论及富氦资源勘探思路

石油勘探与开发 2024年第5期51卷 1160-1174页

作者：秦胜飞窦立荣陶刚李济远齐雯李晓斌郭彬程赵姿卓王佳美中国石油勘探开发研究院北京100083 中国石油勘探开发研究院西北分院兰州730020 中国科学院西北生态环境资源研究院兰州730000

基于国内外重要含油气盆地天然气样品和岩石样品,进行氦气含量、组分、同位素及岩石样品中U、Th含量分析,对氦气富集机理、富集模式、分布规律和勘探思路等进行研究。研究认为,能否形成富氦气藏取决于气藏中氦气的供给量和天然气对氦气... 详细信息

基于国内外重要含油气盆地天然气样品和岩石样品,进行氦气含量、组分、同位素及岩石样品中U、Th含量分析,对氦气富集机理、富集模式、分布规律和勘探思路等进行研究。研究认为,能否形成富氦气藏取决于气藏中氦气的供给量和天然气对氦气的稀释程度,其富集成藏特征可以概括为“多源供氦、主源富氦;氦氮伴生、同溶共聚”。氦气主要来自岩石中U和Th的放射性衰变,所有岩石都含有微量的U和Th,都可为气藏提供一定的氦源,但以花岗岩或变质岩为主的大型古老基底往往是富氦气藏的主力氦源。古老基底中的U和Th经历漫长地质历史时期的衰变生成的氦气连同基底岩石中无机含氮化合物裂解生成的氮气溶解在水中,随构造抬升,地层水沿断裂往上运移至气藏并释放出氦和氮气,使气藏同时富集氦和氮气,氦氮的伴生关系十分明显。在东部拉张型盆地,构造活动强烈,天然气中混有一定比例的幔源氦气。富氦气藏大多发育于有断裂沟通的古老基底之上、后期经历大幅度构造抬升、盖层封盖能力适中、天然气充注强度中等、地下水比较活跃的常压或低压区。氦气勘探须放弃以寻找天然气甜点和高产大气田的传统“兼探”思路,根据氦气富集特点,寻找有断裂并与古老基底沟通、晚期构造抬升幅度较大、盖层封盖能力相对较弱、天然气充注强度不高、古老地层水较丰富的气藏。

关键词：氦气富氦气藏富集理论分布规律主控因素勘探思路

Periconceptional Folic Acid Only Versus Multiple Micronutrients Containing Folic Acid and Association with Gestational Diabetes Mellitus-Beijing Municipality,China,2017-2021

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China CDC weekly 2023年第23期5卷 505-510页

作者： Shuangbo Xia Yushan Du Ziyang Ren Jinjuan Zhang Suhong Gao jiamei wang Zhiwen Li Xiaohong Liu Jufen Liu Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Institute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health Peking UniversityBeijingChina Department of Child Health Beijing Haidian Maternal and Child Health HospitalBeijingChina Department of Gynaecology and Obstetrics Beijing Haidian Maternal and Child Health HospitalBeijingChina

Summary What is already known about this topic?Inconsistent results have been reported on the association between periconceptional folic acid only(FAO)or multiple micronutrients containing folic acid(MMFA)supplementation and the risk of gestational diabetes mellitus(GDM)in previous *** is added by this report?In a prospective cohort study conducted among pregnant women in Haidian District,Beijing Municipality,it was observed that those who took MMFA demonstrated a higher likelihood of developing GDM in comparison to those who consumed FAO ***,the increased risk for GDM in pregnant women supplemented with MMFA compared to FAO was primarily due to changes in fasting plasma *** are the implications for public health practice?It is highly recommended that women prioritize the use of FAO in order to yield potential benefits in the prevention of GDM.

关键词： prevention Diabetes conception

Rate of Correct Use of Folic Acid Supplementation Among Pregnant Women—Beijing Municipality,China,2017–2019

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China CDC weekly 2021年第37期3卷 783-787页

作者： Qinfeng Song Jing Wei jiamei wang Le Zhang Xiaohong Liu Yali Zhang Nan Li Zhiwen Li Institute of Reproductive and Child Health Peking University/Key Laboratory of Reproductive HealthNational Health Commission of the People’s Republic of ChinaBeijingChina Department of Epidemiology and Biostatistics School of Public HealthPeking UniversityBeijingChina Cancer Center of Shanxi Bethune Hospital Shanxi Academy of Medical ScienceTaiyuanShanxiChina Haidian Maternal and Child Health Hospital BeijingChina.

Summary What is already known on this topic?Neural tube defects can be effectively prevented by folic acid ***,compliance with the recommendations for supplementation is still low in *** is added by this report?This study investigated the rate of correct use of folic acid supplementation and its risk factors among pregnant women in Beijing.

关键词： China. Pregnant defects

Graphene Nanoribbons Enhancing the Electronic Conductivity and Ionic Diffusion of Graphene Electrodes for High-Performance Microsupercapacitors

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Energy & Environmental Materials 2024年第4期7卷 285-294页

作者： Yan Zhang Huandi Zhang Xiaoxiao wang Xiaowei Shi Zehua Zhao Yaling wang jiamei Liu Cheng Tang Guolong wang Lei Li State Key Laboratory for Mechanical Behavior of Materials School of Materials Science and Engineering Xi'an Jiaotong University Center for Materials Chemistry Frontier Institute of Science and TechnologyXi'an Jiaotong University Instrument Analysis Center of Xi'an Jiaotong University Xi'an Jiaotong University

The electrochemical performance of microsupercapacitors with graphene electrodes is reduced by the issue of graphene sheets aggregation,which limits electrolyte ions penetration into *** the space between graphene sheets in electrodes facilitates the electrolyte ions penetration,but sacrifices its electronic conductivity which also influences the charge storage ability.

关键词： areal energy density graphene graphene nanoribbons microsupercapacitors structure engineering

252例过敏性哮喘患者体质分布特征及临床资料分析

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中国实验方剂学杂志 2024年第16期30卷 110-116页

作者：张诗瑜崔红生高英洁弓雪峰王佳美吕明圣候丹张馨予郭琦黄贵锐程思益张志杰北京中医药大学第三附属医院北京100029 北京中医药大学北京100029

目的:通过横断面研究的方法,分析过敏性哮喘患者兼夹体质的分布特点,为过敏性哮喘的调体及治疗提供依据。方法:选取于2021年12月至2023年9月门诊就诊的过敏性哮喘患者,采用问卷调查的方式,收集患者的临床资料,分析过敏性哮喘患者的兼夹... 详细信息

目的:通过横断面研究的方法,分析过敏性哮喘患者兼夹体质的分布特点,为过敏性哮喘的调体及治疗提供依据。方法:选取于2021年12月至2023年9月门诊就诊的过敏性哮喘患者,采用问卷调查的方式,收集患者的临床资料,分析过敏性哮喘患者的兼夹体质分布规律及过敏性哮喘特禀质患者性别、年龄、体质量指数、合并过敏性疾病、过敏史、家族史、蓄养宠物情况、呼出气一氧化氮等与体质的相关性。结果:研究共纳入过敏性哮喘患者252例,男女比为1∶1.5,青年占比最高。单纯特禀质占比最高,特禀质兼夹其他体质依次为阳虚质、气虚质、气郁质、痰湿质、湿热质、阴虚质、和血瘀质。兼夹一种体质有58例,阳虚质占比最高。兼夹两种体质有38例,气虚质+阳虚质数量最多。超重或肥胖患者共116例;共48例患者有过敏性疾病家族史,117例患者有过敏史;70例患者养宠物,养宠物与对猫狗毛过敏有相关性(P<0.05);202例的患者合并其他过敏性疾病,过敏性鼻炎、荨麻疹和湿疹是合并最多的三类疾病;嗜酸性气道炎症患者有177人。过敏性哮喘证型依次排列为风哮证134例(53.17%)、热哮证51例(20.24%)、寒哮证32例(12.7%)、虚哮证15例(5.95%)、气郁哮证14例(5.56%)、瘀哮证6例(2.38%)。二元Logistic回归分析结果提示,女性阳虚质与气郁质较男性多;年龄越大出现痰湿质与湿热质可能性越小;体质量指数与痰湿质呈正相关,与阳虚质呈负相关(P<0.05)。结论:过敏性哮喘以特禀质为主,风哮证为最常见的证型。特禀质与其他偏颇体质兼夹致使过敏性哮喘反复发作,兼夹体质中气虚质、阳虚质多见。过敏性哮喘中女性、青年发病率更高,女性更易兼夹阳虚质和气郁质。肥胖可能是过敏性哮喘的重要危险因素,肥胖者更易兼夹痰湿质和湿热质。宠物接触、过敏性鼻炎可能与过敏性哮喘控制不佳有关。

关键词：过敏性哮喘体质特点特禀质兼夹体质临床资料