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眼科术后感染性眼内炎的回顾性分析

国际眼科杂志 2024年第12期24卷 2016-2019页

作者：张茵马清敏牛佳琳王建民河北省人民医院眼科河北省石家庄市050051

目的:分析不同类型眼科术后感染性眼内炎的致病菌、耐药性、治疗方法及预后。方法:回顾性分析。选取河北省人民医院眼科2009-01/2023-06收治的眼科术后感染性眼内炎患者37例37眼。分析不同类型眼科术后感染性眼内炎的致病菌、耐药性、... 详细信息

目的:分析不同类型眼科术后感染性眼内炎的致病菌、耐药性、治疗方法及预后。方法:回顾性分析。选取河北省人民医院眼科2009-01/2023-06收治的眼科术后感染性眼内炎患者37例37眼。分析不同类型眼科术后感染性眼内炎的致病菌、耐药性、早期玻璃体腔注射抗生素或玻璃体切除联合硅油填充术的治疗效果。结果:纳入术后感染性眼内炎患者37眼中,白内障超声乳化摘除联合人工晶状体植入术后24眼,玻璃体切除术后4眼,青光眼白内障联合术后2眼,抗青光眼术后2眼,角膜移植术后2眼,前房穿刺术后2眼,玻璃体腔注药术后1眼。眼内液标本送检37例(玻璃体+房水14例,单纯玻璃体20例,单纯房水3例),检出致病菌20株,其中革兰氏阳性菌17株(12例为表皮葡萄球菌),革兰氏阴性菌2株,真菌1株(镰刀菌)。37眼中行单纯玻璃体腔注药7眼、玻璃体腔注药联合玻璃体切除11眼、单纯玻璃体切除19眼。末次随访时,最佳矫正视力(BCVA)≤0.05者15眼,0.06-0.3者15眼,0.4-1.0者7眼,与治疗前(无光感-手动者31眼,数指-0.05者3眼,0.06-0.3者3眼)有差异(P<0.001)。结论:对于眼内感染相对较轻、初诊视力相对较好的眼科术后感染性眼内炎患者,玻璃体腔注射抗生素仍然是一种经济有效的治疗手段。早期进行玻璃体切除术可以有效控制眼科术后感染性眼内炎的进展,减少手术次数,显著提高视力。

关键词：感染性眼内炎致病菌耐药性眼内炎的治疗

斜视术后眼表及睑板腺功能变化的危险因素分析

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临床眼科杂志 2024年第3期32卷 242-246页

作者：赵智华李科军张茵牛佳琳河北省人民医院眼科石家庄050000

目的探讨斜视患者术后眼表及睑板腺功能变化及其危险因素分析。方法回顾性病例对照研究。选取2019年1月至2021年6月我院收治的126例(188只眼)斜视患者为研究对象,根据手术切口将患者分为角膜缘切口组(A组)、跨肌止端切口组(B组)、近穹... 详细信息

目的探讨斜视患者术后眼表及睑板腺功能变化及其危险因素分析。方法回顾性病例对照研究。选取2019年1月至2021年6月我院收治的126例(188只眼)斜视患者为研究对象,根据手术切口将患者分为角膜缘切口组(A组)、跨肌止端切口组(B组)、近穹隆切口组(C组)三个组别,分别于术后1周、术后1个月、术后6个月观察患者的眼表与睑板腺功能变化,并分析眼表与睑板腺功能变化的单因素,采用Logistic回归分析进一步明确影响斜视患者术后眼表与睑板腺功能变化的因素。结果眼表疾病评分指数(OSDI)、角膜上皮荧光染色评分(CFSS)、泪膜脂质层厚度(LLT)、SchirmerⅠ试验(SⅠt)、泪膜破裂时间(TBUT)、睑板腺开口评分的组间比较有统计学意义(F_(组间)=35.912、28.093、32.115、35.021、32.984、35.765,P0.05)。发病年龄、病程、无控制正位、术后无立体视觉训练、手术切口、手术累及肌肉数目是影响斜视患者眼表与睑板腺功能恢复的影响因素(P9岁、病程>1年、手术行角膜缘切口或跨肌止端切口、手术累及肌肉数目≥2条、术后无立体视觉训练是影响斜视患者术后眼表与睑板腺功能恢复的独立危险因素(P9岁、病程>1年、手术行角膜缘切口或跨肌止端切口、手术累及肌肉数目≥2条、术后无立体视觉训练均是影响斜视患者术后眼表与睑板腺功能恢复的危险因素。

关键词：斜视眼表功能睑板腺功能手术危险因素

一种基于直方图对称关联度的电流互感器饱和检测算法

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中国电力 2016年第12期49卷 42-47页

作者：王宇恩高昌培白加林牛静赵武智赵建新黄婷马玉龙贵州电网有限责任公司电力调度控制中心贵州贵阳550002 北京四方继保自动化股份有限公司技术支持部北京100085 华北电力大学电气与电子工程学院北京102206

电流互感器(TA)饱和是一种物理现象,可能导致保护继电器的误动作。针对这种现象,提出一种利用频率分布直方图结合关联度的方法检测TA的饱和情况。首先对TA二次侧电流进行采样分析,然后利用波形镜像变换技术将波形变换,并做出其直方图,... 详细信息

电流互感器(TA)饱和是一种物理现象,可能导致保护继电器的误动作。针对这种现象,提出一种利用频率分布直方图结合关联度的方法检测TA的饱和情况。首先对TA二次侧电流进行采样分析,然后利用波形镜像变换技术将波形变换,并做出其直方图,计算出其对称关联度,与定值比较即可判断TA是否发生饱和。算法简单可靠,具有精度高,计算速度快的特点,对于继电保护领域检测TA饱和,提高保护动作的可靠性,维护系统正常运行等方面具有重要的参考意义。

关键词： TA饱和直方图对称关联度保护波形镜像变换

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2型糖尿病患者干眼症发生的影响因素分析

现代中西医结合杂志 2024年第19期33卷 2660-2664,2738页

作者：牛佳琳李焕丽张茵李科军王建民河北省人民医院河北石家庄050000

目的观察不同糖尿病病程、糖化血红蛋白(HbA1c)水平及中医证型2型糖尿病患者干眼症相关指标的差异,探讨糖尿病患者发生干眼症的影响因素。方法选取2019年1月—2021年1月在河北省人民医院就诊的2型糖尿病患者130例,按照糖尿病病程分为病... 详细信息

目的观察不同糖尿病病程、糖化血红蛋白(HbA1c)水平及中医证型2型糖尿病患者干眼症相关指标的差异,探讨糖尿病患者发生干眼症的影响因素。方法选取2019年1月—2021年1月在河北省人民医院就诊的2型糖尿病患者130例,按照糖尿病病程分为病程0.05)。不同病程和不同HbA1c分组糖尿病患者MGP均明显高于对照组(P均0.05);病程≥10年组患者的SPEED评分和MGP均明显高于病程0.05);HbA1c≥7%组患者的BUT、SIt、MGYSS评分均明显低于HbA1c0.05);与阴虚内热组比较,气阴两虚组患者BUT明显降低而MGP明显升高(P均<0.05);阴阳两虚组患者LLT明显降低而MGP明显升高(P均<0.05);与气阴两虚组比较,阴阳两虚组患者MGYLS评分和MGYSS评分均明显升高(P均<0.05)。结论2型糖尿病患者睑板腺结构和功能均出现异常改变,泪膜质量下降,导致各种眼表不适,其中血糖控制欠佳、病程较长患者的眼表不适及睑板腺异常更严重,更易发生干眼;患者中气阴两虚型居多,该型患者主要表现为睑板腺缺失和泪膜破裂时间缩短,有助于指导防治。

关键词： 2型糖尿病干眼症泪膜睑板腺功能

Geometrical design of variable ratio tooth profile based on Boolean subtraction operation and a novel modification method

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International Journal of Agricultural and Biological Engineering 2020年第5期13卷 125-133页

作者： Ziru niu Jianlei Li Shuai Xin Liangliang Zou Yuhua Li jialin Hou Ming Tu Ting Sun College of Mechanical and Electronic Engineering Shandong Agricultural UniversityTai’an 271018ShandongChina Shandong Provincial Key Laboratory of Horticultural Machinery and Equipment Tai’an 271018ShandongChina College of Engineering Huazhong Agricultural UniversityWuhan 430070China Key Laboratory of Agricultural Equipment in Mid-lower Reaches of the Yangtze River Ministry of Agriculture and Rural AffairsWuhan 430070China Shandong Huasheng Pesticide Machinery Co. LtdLinyi 276017ShandongChina

Variable transmission ratio racks show great potential in rice transplanters as a key component of variable transmission ratio steering to balance steering portability and *** objective of this study was to develop a novel geometrical design method to achieve quick,high-quality modeling of the free curvilinear tooth profile of a variable transmission ratio ***,a discrete envelope motion 3D model was established between the pinion-sector and the variable transmission ratio rack blank based on the mapping relationship between the rotation angle of the pinion-sector and the displacement of the rack,according to the variable transmission ratio *** on the loop Boolean subtraction operation,which removed the pinion-sector from the rack blank during all moments of the discrete motion process,the final complex changing tooth shape of the variable transmission ratio rack was ***,since Boolean cutting residues made the variable ratio tooth surface fluctuant and eventually affected the precision of the model,this study proposed a modification method for establishing a smooth and continuous tooth ***,a novel fitting algorithm used approximate variable ratio tooth profile points extracted from the Boolean cutting marks and generated a series of variable ratio tooth profiles by utilizing B-spline with different ***,based on a transmission stability simulation,the variable ratio tooth profile with optimal dynamic performance was selected as the final ***,tests contrasting the transmission stability of the machining samples of the initial variable ratio tooth profile and the final variable ratio tooth profile were *** results indicated that the final variable ratio tooth profile is more effective than the initial variable ratio tooth ***,the proposed variable ratio tooth profile modeling and modification method for eliminating Boolean cutting residues and improving surface accuracy is prov

关键词： rice transplanter steering variable ratio tooth profile variable ratio curve Boolean subtraction operation transmission stability

Design and Optimization of Planting Process Parameters for 2ZYX-2 Type Green Onion Ditching and Transplanting Machine

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Phyton-International Journal of Experimental Botany 2020年第1期89卷 147-166页

作者： Jiqiang Zhang Ziru niu Tianhua Li Yanqiang Wu Rui Xi Yuhua Li Guanghua Li jialin Hou College of Mechanical and Electronic Engineering Shandong Agricultural UniversityTai’an271018China College of Horticultural Science and Engineering Shandong Agricultural UniversityTai’an271018China Qingzhou Hualong Machinery Technology Development Co. Ltd.Qingzhou262500China

Considering the current low level of mechanization for domestic green onion planting and the high labor intensity of artificial planting,a 2ZYX-2 green onion ditching and transplanting machine,which can complete ditching,ridging,transplanting,repression,soil covering and other operations,is designed in this *** Central Composite test design method was carried out with the speed of the transplanting machine,the depth of the opener and the horizontal position of the opener as the experimental factors and with the qualification ratio of perpendicularity,the variation coefficient of the plant spacing and the qualification ratio of the planting depth as the test *** the analysis of the model interaction and response surface,the change laws that the influence the machine’s forward speed,the depth of the opener and the horizontal position of the opener were *** regression model was optimized by Design-Expert 8.0.6 software,and the accuracy of the predicted results was verified by *** optimal working parameters showed that the forward speed of the machine was 0.06 m/s,the depth of the opener was 102 mm,and the horizontal position of the opener was 29 *** conditions of optimal working parameters,the qualification rate of the verticality was 86.83%,the coefficient of variation for the plant spacing was 2.77,and the pass rate of planting depth was 88.26%.The research related to the thesis can provide a reference for the mechanized planting of green onion,which is of great significance to the cost-effectiveness of the green onion industry.

关键词： Agricultural machinery motion analysis green onion experiment

A general synthesis of inorganic nanotubes as high-rate anode materials of sodium ion batteries

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Journal of Energy Chemistry 2023年第2期77卷 369-375,I0010页

作者： Chunting Wang Ningyan Cheng Zhongchao Bai Qinfen Gu Feier niu Xun Xu jialin Zhang Nana Wang Binghui Ge Jian Yang Yitai Qian Shixue Dou Key Laboratory of Colloid and Interface Chemistry Ministry of EducationSchool of Chemistry and Chemical EngineeringShandong UniversityJinan 250100ShandongChina Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education Institutes of Physical Science and Information TechnologyAnhui UniversityHefei 230601AnhuiChina College of Mechanical and Electronic Engineering Shandong University of Science and TechnologyQingdao 266590ShandongChina Australian Synchrotron 800 Blackburn RoadClaytonVIC 3168Australia College of Chemistry and Materials Engineering Anhui Science and Technology UniversityBengbu 233000AnhuiChina Institute for Superconducting and Electronic Materials University of Wollongong Innovation Campus Innovation Campus Squires WayWollongongNew South Wales 2500Australia Institute of Energy Materials Science(IEMS) University of Shanghai for Science and TechnologyShanghai 200093China

Ino rganic tubular materials have an exceptionally wide range of applications,yet developing a simple and universal method to controllably synthesize them remains *** this work,we report a vaporphase-etching hard-template method that can directly fabricate tubes on various thermally stable oxide and sulfide *** synthesis method features the introduction of a vapor-phase-etching process to greatly simplify the steps involved in preparing tubular materials and avoids complicated postprocessing ***,the in-situ heating transmission electron microscopy(TEM)technique is used to observe the dynamic formation process of TiO_(2-x) tubes,indicating that the removal process of the Sb2S3 templates first experienced the Rayleigh instability,then vapor-phase-etching *** used as an anode for sodium ion batteries,the TiO_(2-x) tube exhibits excellent rate performance of134.6 mA h g^(-1) at the high current density of 10 A g^(-1) and long-term cycling over 7000 ***,the full cell demonstrates excellent cycling performance with capacity retention of 98%after 1000 cycles,indicating that it is a promising anode material for *** method can be expanded to the design and synthesis of other thermally-stable tubular materials such as ZnS,MoS_(2),and SiO_(2).

关键词： Tubular materials In-situ heating TEM Sodium ion batteries TiO_(2) Hard template methods

Loss of Lkb1 impairs Treg function and stability to aggravate graft-versus-host disease after bone marrow transplantation

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Cellular & Molecular Immunology 2020年第5期17卷 483-495页

作者： Xiuhua Su Qianqian Wang Wei Guo Xiaolei Pei Qing niu Maolan Liu Yuanyuan Liu Song Chen Sizhou Feng Yi He Donglin Yang Rongli Zhang Qiaoling Ma Weihua Zhai Aiming Pang jialin Wei Yong Huang Yuechen Luo Mingzhe Han Xiaoming Feng Erlie Jiang State Key Laboratory of Experimental Hematology National Clinical Research Center for Blood DiseasesInstitute of Hematology&Blood Diseases HospitalChinese Academy of Medical Sciences&Peking Union Medical College300020 TianjinChina Department of Hematology the First Affiliated Hospital of Kunming Medical UniversityHematology Research Center of Yunnan Province650000 KunmingChina

Accumulating evidence suggests that a reduction in the number of Foxp3^(+) regulatory T cells(Tregs)contributes to the pathogenesis of acute graft-versus-host disease(aGVHD),which is a major adverse complication that can occur after allogeneic hematopoietic stem cell transplantation(allo-HSCT).However,the precise features and mechanism underlying the defects in Tregs remain largely *** this study,we demonstrated that Tregs were more dramatically decreased in bone marrow compared with those in peripheral blood from aGVHD patients and that bone marrow Treg defects were negatively associated with hematopoietic *** from aGVHD patients exhibited multiple defects,including the instability of Foxp3 expression,especially in response to IL-12,impaired suppressor function,decreased migratory capacity,and increased *** profiling revealed the downregulation of Lkb1,a previously identified critical regulator of murine Treg identity and metabolism,and murine Lkb1-regulated genes in Tregs from aGVHD ***3 expression in human Tregs could be decreased and increased by the knockdown and overexpression of the Lkb1 gene,***,a loss-of-function assay in an aGVHD murine model confirmed that Lkb1 deficiency could impair Tregs and aggravate disease *** findings reveal that Lkb1 downregulation contributes to multiple defects in Tregs in human aGVHD and highlight the Lkb1-related pathways that could serve as therapeutic targets that may potentially be manipulated to mitigate aGVHD.

关键词： allogeneic hematopoietic stem cell transplantation(allo-HSCT) acute graft-versus-host disease(aGVHD) Lkb1 Treg

动力吸振器复合非线性能量阱对线性镗杆系统的振动控制

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力学学报 2021年第11期53卷 3124-3133页

作者：吕嘉琳牛江川申永军杨绍普石家庄铁道大学交通工程结构力学行为与系统安全国家重点实验室石家庄050043 石家庄铁道大学机械工程学院石家庄050043

研究了线性动力吸振器复合非线性能量阱对线性镗杆在外部简谐激励下的振动控制.忽略镗杆系统中的非线性因素,建立了附加线性动力吸振器和非线性能量阱的镗杆系统的三自由度运动方程,研究了附加复合式动力吸振器的镗杆系统的受迫振动.通... 详细信息

研究了线性动力吸振器复合非线性能量阱对线性镗杆在外部简谐激励下的振动控制.忽略镗杆系统中的非线性因素,建立了附加线性动力吸振器和非线性能量阱的镗杆系统的三自由度运动方程,研究了附加复合式动力吸振器的镗杆系统的受迫振动.通过平均法得到了附加复合式动力吸振器的镗杆系统的近似解析解,并利用数值解验证了近似解析解的准确性,两者具有很好的一致性.利用近似解析解详细分析了线性动力吸振器和非线性能量阱的参数对镗杆振动抑制性能的影响.对给定质量的复合式动力吸振器进行了参数优化,其中线性动力吸振器参数采用H;优化方法的近似解析解进行了优化,非线性能量阱的阻尼利用系统的近似解析解进行了优化.分析结果表明,线性动力吸振器与非线性能量阱组合可以有效抑制线性镗杆系统的振动,而且采用参数优化后的复合式动力吸振器可以获得更好的减振效果.通过附加非线性能量阱,不但可以提高线性动力吸振器的振动抑制效果,而且还可以提高振动控制系统的鲁棒性.

关键词：振动控制动力吸振器非线性能量阱近似解析解