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Analysis on patents of health care products with substances of medicine food homology in China

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Chinese Herbal Medicines 2024年第3期16卷 412-421页

作者： Haibo Liu Yanfeng Wang jiali huang Zhengqi Dong Peigen Xiao Institute of Medicinal Plant Development Chinese Academy of Medical Sciences and Peking Union Medical College Key Laboratory of Traditional Chinese Medicine Patent Information Resources State Administration of Traditional Chinese Medicine Beijing Academy of Science and Technology

Objective:The concept of substances of medicine food homology(SMFH) has garnered significant attention in recent years.This study conducts a systematic analysis of patent literature related to SMFH,and elucidates the development trends,technical hotspots,and the overall patent protection landscape of SMFH in China over the past two decades.Methods:The patent search focused on the SMFH varieties as the objects of inquiry,with retrieval conducted in patent databases.Subsequently,the acquired data underwent processing,analysis,and visualization.Results:While the technical threshold for pharmaceutical applications surpasses that of the food service sector,the former may assume a prominent role in the future.Research and development(R&D) activities in the southeast of China demonstrate robust activity than other regions.Colleges and scientific research institutions exhibit substantial advantages in patent applications compared with individuals and hold greater potential for future development.Conclusion:The findings of this patent analysis indicate that China's SMFH industry are presently undergoing a transition from an extensive model to a high-quality model. The quality and technical standards of SMFH products are consistently improving.Consequently,there is a need for more stringent patent application requirements to align with the evolving development needs.

关键词： patent analysis patent pattern substances of medicine food homology traditional Chinese medicine

Recent advances in the synthesis of benzo[b]thiophene fused polycyclic derivatives:Strategies and reactions

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Chinese Chemical Letters 2023年第6期34卷 49-69页

作者： jiali huang Wenyang Wang Lei Zhang Xiangtai Meng Tianjin Key Laboratory of Organic Solar Cells and Photochemical Conversion School of Chemistry&Chemical EngineeringTianjin University of TechnologyTianjin 300384China Tianjin Engineering Technology Center of Chemical Wastewater Source Reduction and Recycling School of ScienceTianjin Chengjian UniversityTianjin 300384China

Benzo[b]thiophene fused compounds with a unique active heterocyclic skeleton have wide applications in the fields of medicinal chemistry,organic synthesis,and organic functional materials,which resulted in rapid development of many efficient methods for the construction of benzo[b]thiophenefused heterocycles in recent years.Among these methods,the domino reaction of benzo[b]thiophene derivatives is a practical and powerful synthetic route to access benzo[b]thiophene-fused heterocycles by virtue of the particularity of sulfur atom.This review summarizes the latest developments in the construction of benzo[b]thiophene-fused heterocycles by ring formation at the C2-C3-position of benzo[b]thiophene derivatives in the past decade.Additionally,this review is divided into four parts according to the four kinds of benzo[b]thiophene derivatives used,including thioaurone,thioisatin,substituted benzo[b]thiophene,and azadiene.

关键词： Benzo[b]thiophene fused polycyclic derivatives Thioaurone Thioisatin Benzo[b]thiophene Azadiene

Representation of the coherent state for a beam splitter operator and its applications

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Communications in Theoretical Physics 2022年第3期74卷 11-19页

作者： Mingxia Zhan Fang Jia jiali huang Huan Zhang Liyun Hu Center for Quantum Science and Technology Jiangxi Normal UniversityNanchang 330022China Institute for Military-civilian integration of Jiangxi province Nanchang 330029China

A beam splitter operator is a very important linear device in the field of quantum optics and quantum information.It can not only be used to prepare complete representations of quantum mechanics,entangled state representation,but it can also be used to simulate the dissipative environment of quantum systems.In this paper,by combining the transform relation of the beam splitter operator and the technique of integration within the product of the operator,we present the coherent state representation of the operator and the corresponding normal ordering form.Based on this,we consider the applications of the coherent state representation of the beam splitter operator,such as deriving some operator identities and entangled state representation preparation with continuous-discrete variables.Furthermore,we extend our investigation to two single and two-mode cascaded beam splitter operators,giving the corresponding coherent state representation and its normal ordering form.In addition,the application of a beam splitter to prepare entangled states in quantum teleportation is further investigated,and the fidelity is discussed.The above results provide good theoretical value in the fields of quantum optics and quantum information.

关键词： beam splitter operator coherent state representation the technique of integration within product of operator quantum teleportation

3D anchoring structured for LiFe_(0.5)Mn_(0.5)PO_(4)@cornstalk-C cathode materials

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中国化学快报:英文版 2023年第8期34卷 302-305页

作者： Guangliang Zhang Riran Zang Man Mo Zhijie Fang Yangxian huang Kunsong Hu jiali huang Xinxiang Liu Lingyun huang Guohui Kang Weijian Li Haiqing Zhan Xianquan Ming Guanhan huang Guiliang Li Feng Zhan School of Resources Environment and Materials Guangxi UniversityNanning 530004China School of Electronics Engineering Guangxi University of Science and TechnologyLiuzhou 545006China State Key Laboratory of Featured Metal Materials and Life-cycle Safety for Composite Structures Guangxi UniversityNanning 530004China Guangxi Higher Education Key Laboratory of High Performance Structural Materials and Heat Treatment&Surface Processing Guangxi UniversityNanning 53004China South Manganese Group Limited Nanning 530029China

The organic carbon source coating LiFe_(x)Mn_(1-x)PO_(4)suffers from the problem of non-uniform carbon cladding.Too thick carbon cladding layer instead hinders the de-embedding of lithium ions.In this paper,we choose cornstalk as the carbon source,then LiFe_(0.5)Mn_(0.5)PO_(4)@cornstalk-C(LFMP@C-C)with 3D anchoring structure is prepared by the solvothermal method.The results show that the LFMP with cornstalk as the carbon source has better performance compared to the sucrose-coated LFMP material(LFMP@C).The discharge capacity of LFMP@C-C is 116 mAh/g for the first cycle at 1 C and the capacity retention rate is 94.0%after 500 cycles,and the discharge capacity of LFMP@C-C is more than 17.17%higher than that of LFMP@C.

关键词： LiFe_(0.5)Mn_(0.5)PO_(4) Cornstalk Solvothermal method 3D anchoring structure Cathode materials

数字化时代欠发达地区乡村中小学教师TPACK的组态构型与提升策略

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教育科学研究 2024年第2期 20-26页

作者：肖立黄嘉莉湖北第二师范学院教育科学学院(湖北教师教育研究中心) 430205 北京师范大学教师教育研究中心 100875

大数据、人工智能等一系列新技术变革要求教师优化“整合技术的学科教学知识(TPACK)”以适应数字时代的教育需求。研究以TPACK“六边模型”为框架,采用定性比较分析法(QCA)实证探索80位乡村中小学教师的TPACK发展水平。通过TPACK不同知... 详细信息

大数据、人工智能等一系列新技术变革要求教师优化“整合技术的学科教学知识(TPACK)”以适应数字时代的教育需求。研究以TPACK“六边模型”为框架,采用定性比较分析法(QCA)实证探索80位乡村中小学教师的TPACK发展水平。通过TPACK不同知识维度之间“联合效应”的匹配关系,将教师分为“努力适应”、“创新进取”和“消极回避”三种类型的组态构型。研究进一步提出,通过构建“教学教研共学共商”的网络技术教研共同体、畅通“以城带乡共融共生”的教师轮岗交流通道、创建“家校社共测共评”的协同评估机制等提升策略,推动乡村中小学优秀教师TPACK的内涵化可持续拓展,助力乡村基础教育高质量数字化均衡发展。

关键词：欠发达地区乡村中小学教师 TPACK

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语法和语义线索对儿童动词习得的影响

心理学报 2024年第1期56卷 61-69页

作者：陈永香裴斐斐黄佳丽湖南师范大学教育科学学院长沙410006 山西大学教育科学学院太原030006

口语词汇习得过程中存在语法促进和语义促进效应,而语法又包含了句法和词法。本研究采用优先指向范式考察了语法和语义线索对汉语儿童动词习得的影响。实验1发现,5岁儿童可以利用单个句法线索词习得动词。实验2发现,4岁儿童可以在增加... 详细信息

口语词汇习得过程中存在语法促进和语义促进效应,而语法又包含了句法和词法。本研究采用优先指向范式考察了语法和语义线索对汉语儿童动词习得的影响。实验1发现,5岁儿童可以利用单个句法线索词习得动词。实验2发现,4岁儿童可以在增加句法线索词或语义线索词条件下习得动词;实验2a发现,4岁儿童更倾向于将单音节词判定为动词,实验2b发现,在增加语义线索词条件下,3岁儿童更倾向于将双音节词判定为名词。结果表明,5岁儿童可以利用单个句法线索词习得动词,4岁儿童可以通过多重线索习得动词。本研究拓展了以往关于汉语儿童动词习得的结果,提示语言习得研究应考虑语法线索的独特性和可靠性。

关键词：动词习得句法促进汉语儿童词长

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教师教育学科建设的系谱学考察

教师教育研究 2024年第1期36卷 1-7页

作者：黄嘉莉李秀云教育部普通高校人文社会科学重点研究基地北京师范大学教师教育研究中心北京100875 伊犁师范大学新疆伊宁835000

本研究基于系谱学的历史分析视角,认为教师教育学科不该被束缚于传统学科制度的认识限制,而应重新审视知识与制度运作的权力密切相关,从而探究建设路径。以往大学学科制度强调理性知识的优先发展,引发教师教育进入大学后的话语争议,这... 详细信息

本研究基于系谱学的历史分析视角,认为教师教育学科不该被束缚于传统学科制度的认识限制,而应重新审视知识与制度运作的权力密切相关,从而探究建设路径。以往大学学科制度强调理性知识的优先发展,引发教师教育进入大学后的话语争议,这反映出教师教育知识的实践特征被排除在制度权力的行使之外,也体现出教师教育知识的发展缺乏与制度权力的相关性。因此,教师教育学科建设应该重新认识学科制度权力和知识的关系,以教师教育核心知识为基础,开放知识边界,从课程制度、教师资格制度、评价制度和认证制度的权力行使中,体现教师教育学科知识的合法性、价值性、功能性,进而重构教师教育学科的学术体系。

关键词：教师教育学科教师教育学科知识系谱学知识权力

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城市燃气管网运行安全现状分析与措施建议

上海煤气 2024年第2期 29-31页

作者：黄佳丽上海能源建设工程设计研究有限公司

燃气在输送过程存在系统自身事故和外界自然、社会因素等多种风险。一旦发生燃气事故,将影响到城市运行,妨碍工业生产和影响居民生活。基于城市燃气管网运行安全现状,结合燃气事故原因分析,提出燃气管网运行安全策略,并提出燃气行业高... 详细信息

燃气在输送过程存在系统自身事故和外界自然、社会因素等多种风险。一旦发生燃气事故,将影响到城市运行,妨碍工业生产和影响居民生活。基于城市燃气管网运行安全现状,结合燃气事故原因分析,提出燃气管网运行安全策略,并提出燃气行业高质量发展的建议与措施。

关键词：燃气安全管网运行安全高质量发展

基于德尔菲法初步构建急性前葡萄膜炎患者报告结局量表

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中华眼视光学与视觉科学杂志 2024年第7期26卷 507-515页

作者：黄栖唐乐微刘茹茹林丹黄佳丽彭雯清李一靖陈燕燕王毓琴温州医科大学附属眼视光医院国家眼耳鼻喉疾病(眼部疾病)临床医学研究中心温州

目的: 基于德尔菲法初步编制《急性前葡萄膜炎患者报告结局量表(AAU-PROs)》, 为评估患者临床结局及选择治疗方案提供参考依据。方法: 描述性研究。通过文献检索和半结构式访谈拟定量表初始条目并编制专家咨询函。采用德尔菲法于2023年1... 详细信息

目的: 基于德尔菲法初步编制《急性前葡萄膜炎患者报告结局量表(AAU-PROs)》, 为评估患者临床结局及选择治疗方案提供参考依据。方法: 描述性研究。通过文献检索和半结构式访谈拟定量表初始条目并编制专家咨询函。采用德尔菲法于2023年10—11月对北京、上海、浙江等地的19名专家进行2轮咨询, 专家对条目重要性、咨询内容的熟悉程度及判断依据评分。以条目重要性评分均值>3.5分、满分比>20%、变异系数<0.25作为条目筛选参考, 再结合专家意见经研究小组充分讨论确定条目。结果: 2轮咨询的专家积极系数均为100%;专家权威系数分别为0.91和0.94;肯德尔协调系数分别为0.216和0.268, 差异均具有统计学意义(均P<0.001)。最终确定AAU-PROs包括4个领域、9个维度、33个条目。结论: 该研究构建的AAU-PROs具有科学性和实用性, 可评估患者的临床结局和生活质量。

关键词：德尔菲法急性前葡萄膜炎患者报告结局