检索结果-南通市图书馆

Novel high-safety aeroengine performance predictive control method based on adaptive tracking weight

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Aeronautics 2024年第7期37卷 352-374页

作者： Qian CHEN Hanlin SHENG Jie ZHANG jiacheng li College of Energy and Power Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China College of Automation Engineering Nanjing University of Aeronautics and AstronauticsNanjing 210016China

Increasing attention has been attracted to the dynamic performance and safety of advanced performance predictive control systems of the next-generation *** latest research demonstrates that Subspace-based Improved Model Predictive Control(SIMPC)can overcome the difficulty in solving the predictive model in MPC/NMPC ***,applying constant design parameters cannot maintain consistent control effects in all ***,the designed system relies too much on sensor-measured data,and thus it is difficult to thoroughly validate the safety of the system because of its high *** means that any potential hardware/software faults will endanger the ***,this paper first presents a novel nonlinear mapping relationship to adaptively tune the tracking weight online with the change of Power Lever Angle(PLA)and real-time relative tracking ***,without introducing additional design parameters,an Adaptive Tracking Weight-based SIMPC(ATW-SIMPC)controller is designed to improve the control performance in all operating states ***,a Primary/Backup Hybrid Control(PBHC)strategy with the ATW-SIMPC controller as the primary system and the traditional speed(Nf)controller as the backup system is proposed to ensure *** designed affiliated switching controller and the real-time monitor therein can be used to realize reasonable and smooth switching between primary/backup systems,so as to avoid bump *** PBHC system switches to the Nf controller when the ATW-SIMPC controller is wrong because of potential hardware/software faults;otherwise,the ATW-SIMPC controller keeps acting on the *** main results prove that the ATW-SIMPC controller with the optimal nonlinear mapping relationship,compared with the existing SIMPC controller,uplifts the dynamic control performance by 32%and reduces overshoots to an allowable limit,resulting in a better control effect in full *** comparison results consistently i

关键词： Aeroengine Model predictive control Hybrid system Adaptive weight Safety

Analyzing the spatiotemporal evolution and driving forces of gross ecosystem product in the upper reaches of the Chaobai River Basin

在线全文

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2024年第8期18卷 117-132页

作者： jiacheng li Qi Han liqiu Zhang li Feng Guihuan liu Beijing Key Laboratory for Source Control Technology of Water Pollution College of Environmental Science and EngineeringBeijing Forestry UniversityBeijing 100083China Engineering Research Center for Water Pollution Source Control&Eco-remediation College of Environmental Science and EngineeringBeijing Forestry UniversityBeijing 100083China Center of Eco-compensation Chinese Academy of Environmental PlanningMinistry of Ecology of EnvironmentBeijing 100041China

The Chaobai River Basin,which is a crucial ecological barrier and primary water source area within the Beijing-Tianjin-Hebei region,possesses substantial ecological *** gross ecosystem product(GEP)in the Chaobai River Basin is a reflection of ecosystem conditions and quantifies nature’s contributions to humanity,which provides a basis for basin ecosystem service management and *** study investigated the spatiotemporal evolution of GEP in the upper Chaobai River Basin and explored the driving factors influencing GEP spatial *** patterns from 2005 to 2020 were analyzed,and GEP was calculated for 2005,2010,2015,and *** driving factors influencing GEP spatial differentiation were identified using the optimal parameter-based geographical detector(OPGD)*** key findings are as follows:(1)From 2005 to 2020,the main ecosystem types were forest,grassland,and *** areas experienced significant changes,and conversions mainly occurred among urban,water,grassland and agricultural ecosystems.(2)Temporally,the GEP in the basin increased from 2005 to 2020,with regulation services *** the county(district)scale,GEP exhibited a north-west-high and south-east-low pattern,showing spatial differences between per-unit-area GEP and county(district)GEP,while the spatial variations in per capita GEP and county(district)GEP were similar.(3)Differences in the spatial distribution of GEP were influenced by regional natural geographical and socioeconomic *** these factors,gross domestic product,population density,and land-use degree density contributed *** among different driving forces noticeably impacted GEP spatial *** findings underscore the necessity of incorporating factors such as population density and the intensity of land-use development into ecosystem management decision-making processes in the upper reaches of the Chaobai River *** policies

关键词： Ecosystem pattern Gross ecosystem product(GEP) Spatiotemporal evolution Optimal parameter-based geographical detector(OPGD) Chaobai River Basin

黄芪甲苷可缓解MC3T3-E1细胞氧化应激损伤并促进成骨

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

中国组织工程研究 2025年第17期29卷 3529-3536页

作者：张加豪李嘉程温明韬郭艳波骆帝李刚山东中医药大学第一临床医学院山东省济南市250014 山东中医药大学附属医院山东省济南市250014

背景:氧化应激是导致骨质疏松症的主要原因之一,减少氧化应激水平与增加抗氧化防御是治疗骨质疏松症的重要研究方向。研究证实黄芪甲苷具有抗骨质疏松作用,但其作用机制尚不明确。目的:探讨黄芪甲苷对氧化应激条件下MC3T3-E1细胞成骨的... 详细信息

背景:氧化应激是导致骨质疏松症的主要原因之一,减少氧化应激水平与增加抗氧化防御是治疗骨质疏松症的重要研究方向。研究证实黄芪甲苷具有抗骨质疏松作用,但其作用机制尚不明确。目的:探讨黄芪甲苷对氧化应激条件下MC3T3-E1细胞成骨的作用。方法:将MC3T3-E1细胞分4组培养:对照组加入完全培养基,模型组加入含过氧化氢的完全培养基干预24 h后更换为完全培养基,黄芪甲苷组加入含过氧化氢、黄芪甲苷的完全培养基干预24 h后更换为含黄芪甲苷的完全培养基,抑制剂组加入含过氧化氢、黄芪甲苷、细胞外信号调节激酶(extracellular signal-regulated kinases,ERK)抑制剂的完全培养基干预24 h后更换为含黄芪甲苷、ERK抑制剂的完全培养基。过氧化氢干预48 h后,通过丙二醛含量检测黄芪甲苷对MC3T3-E1细胞氧化应激的缓解作用;过氧化氢干预48 h后进行成骨诱导培养,通过碱性磷酸酶染色、茜素红染色验证MC3T3-E1细胞成骨及矿化能力,通过RT-qPCR检测成骨相关基因的表达,Western blot检测成骨相关蛋白及ERK/腺苷酸激活蛋白激酶(AMP-activated protein kinase,AMPK)信号通路蛋白的表达。结果与结论:(1)模型组细胞内碱性磷酸酶含量与矿化结节形成均少于对照组(P<0.05),黄芪甲苷组细胞内碱性磷酸酶含量与矿化结节形成均多于模型组(P<0.05)。(2)与对照组比较,模型组细胞内丙二醛含量增加(P<0.05),骨钙素、RUNX2、Ⅰ型胶原蛋白的mRNA与蛋白表达均降低(P<0.05),AMPK mRNA与p-AMPK蛋白表达升高(P<0.05);与模型组比较,黄芪甲苷组细胞内丙二醛含量减少(P<0.05),骨钙素、RUNX2、Ⅰ型胶原蛋白的mRNA与蛋白表达均升高(P<0.05),ERK1/2、AMPK mRNA表达升高(P<0.05),p-AMPK、p-ERK1/2蛋白表达均升高(P<0.05);ERK抑制剂可部分抑制黄芪甲苷的上述作用。(3)结果表明,黄芪甲苷可通过激活ERK/AMPK信号通路促进氧化应激条件下MC3T3-E1细胞的成骨分化。

关键词：黄芪甲苷骨质疏松症 MC3T3-E1细胞氧化应激 ERK/AMPK信号通路成骨工程化骨材料

On Dual-Mode Driving Control Method for a Novel Unmanned Tractor With High Safety and Reliability

在线全文

学校读者我要写书评

暂无评论

IEEE/CAA Journal of Automatica Sinica 2023年第1期10卷 254-271页

作者： Wei Lu jiacheng li Huanhuan Qin Lei Shu Aiguo Song IEEE the College of Artificial Intelligence Nanjing Agricultural UniversityNanjing 210031China Nanjing Agricultural University Nanjing 210031China Unmanned System Research Institute Northwestern Polytechnical UniversityXi’an 710072China the School of Instrument Science and Engineering Southeast UniversityNanjing 210096China

Due to the non-standardization and complexity of the farmland environment,it is always a huge challenge for tractors to achieve fully autonomy(work at Self-driving mode)all the time in agricultural ***,when tractors work in the Tele-driving(or Remote driving)mode,the operators are prone to fatigue because they need to concentrate for long periods of *** response to these,a dual-mode control strategy was proposed to integrate the advantages of both approaches,i.e.,by combing Self-driving at most of the time with Tele-driving under special(complex and hazardous)conditions through switching control ***,the state switcher was proposed,which is used for smooth switching the driving modes according to different working states of a ***,the state switching control law and the corresponding subsystem tracking controllers were ***,the effectiveness and superiority of the dualmode control method were evaluated via actual experimental testing of a tractor whose results show that the proposed control method can switch smoothly,stably,and efficiently between the two driving modes *** average control accuracy has been improved by 20%and 15%respectively,compared to the conventional Tele-driving control and Self-driving control with low-precision *** conclusion,the proposed dualmode control method can not only satisfy the operation in the complex and changeable farmland environment,but also free drivers from high-intensity and fatiguing *** provides a perfect application solution and theoretical support for the intelligentization of unmanned farm agricultural machinery with high safety and reliability.

关键词： Dual-mode control safety and reliability self-driving(SD) tele-driving(TD) unmanned tractor

CRISPR-CasRx knock-in mice for RNA degradation

在线全文

学校读者我要写书评

暂无评论

Science China(life Sciences) 2022年第11期65卷 2248-2256页

作者： jiacheng li Dekun Zhu Shengshou Hu Yu Nie State Key Laboratory of Cardiovascular Disease Fuwai Hospital and Cardiovascular InstituteNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences&Peking Union Medical CollegeBeijing 100037China National Health Commission Key Laboratory of Cardiovascular Regenerative Medicine Fuwai Central-China HospitalCentral-China Branch of National Center for Cardiovascular DiseasesZhengzhou 450046China

The RNA editing tool CRISPR-CasRx has provided a platform for a range of transcriptome analysis tools and therapeutic approaches with its broad efficacy and high *** enable the application of CasRx in vivo,we established a Credependent CasRx knock-in *** these mice,we specifically knocked down the expression of Meis1 and Hoxb13 in cardiomyocytes,which induced cardiac regeneration after myocardial *** also knocked down the lnc RNA Mhrt in cardiomyocytes with the CasRx knock-in mice,causing hypertrophic *** summary,we generated a Credependent CasRx knock-in mouse that can efficiently knock down coding gene and lnc RNA expression in specific somatic *** in vivo CRISPR-CasRx system is promising for gene function research and disease modeling.

关键词： CRISPR-CasRx CasRx mice in vivo gene knockdown heart regeneration

Effect of reduced graphene oxide-supported copper addition on electrochemical properties of La0.7Mg0.3Ni2.8Co0.5 electrodes

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2019年第12期37卷 1312-1319页

作者： Xiantun Huang Zhiqiang Lan jiacheng li Hao Zhang Jin Guo Department of Materials Science and Engineering Baise CollegeBaise 533000China Guangxi Colleges and Universities Key Laboratory of Novel Energy Materials and Related Technology College of Physics Science and TechnologyGuangxi UniversityNanning 530004China

The reduced graphene oxide-supported copper(Cu@rGO)nanocomposite was introduced to improve the electrochemical properties of La0.7Mg0.3Ni2.8Co0.5alloy *** results show that adding Cu@rGO nanocomposite with mass fractions of x wt%(x=0,3,6 and 9)to the alloy electrodes provides electrodes with maximum discharge capacities of 368.9 mAh/g(x=0),373.2 mAh/g(x=3),407.3 mAh/g(x=6)and 398.6 mAh/g(x=9),and high-rate dischargeabilities at a discharge current density of1200 mA/g of 40.5%(x=0),64.0%(x=3),82.0%(x=6)and 76.0%(x=9).The addition of Cu@rGO nanocomposite also provides alloy electrodes with hydrogen diffusion coefficients of 3.7×10-10 cm2/s(x=0),4.1×10-10 cm2/s(x=3),4.2×10-10 cm2/s(x=6)and 4.0×10-10 cm2/s(x=9).Clearly,the addition of 6 wt%Cu@rGO nanocomposite not only increases the electrochemical capacity of La0.7Mg0.3Ni2.8Co0.5 alloy electrodes,but also improves their electrochemical kinetic properties.

关键词： Kinetic properties Alloy electrode Electrochemical properties Graphene Rare earths

Molecular Characterization and Antibacterial Activity of a G-Type Lysozyme in Yellow Drum(Nibea albiflora)

在线全文

学校读者我要写书评

暂无评论

Journal of Ocean University of China 2024年第2期23卷 477-486页

作者： XIAO Yao li jiacheng TIAN Qianqian WU Baolan HAN Fang State Key Laboratory of Mariculture Breeding Fisheries College of Jimei UniversityXiamen 361021China

Lysozyme(EC3.***.1.17)plays an important role in the immune response;as a nonspecific immune factor,it can resist causative *** can be divided into c-type and g-type in *** a previous study,through genome-wide association analysis,the g-type lysozyme gene,which is named NaLyg in yellow drum(Nibea albiflora),was found to be a key candidate gene for disease resistance in response to Vibrio harveyi *** cDNA of NaLyg was 1025 bp,including four exons and three introns,and its open reading frame(ORF)had a full-length of 582 bp,encoding 193 amino *** was found to be conserved during evolution through bioinformatic *** NaLyg protein possessed a sugar binding domain and three catalytic sites,including Glu71,Asp84 and *** qRT-PCR results confirmed that NaLyg gene mRNA was visibly increased after *** *** NaLyg protein purified by prokaryotic expression killed some gram-negative bacterial pathogens by inducing cell wall destruction,including ***,Aeromonas hydrophila and Edwardsiella ***,the NaLyg protein killed two gram-positive bacteria,Bacillus subtilis and Staphylococcus *** together,the experimental results suggested that the NaLyg protein of *** played an important role in fighting bacterial infections.

关键词： Nibea albiflora innate immunity Vibrio harveyi g-type lysozyme antibacterial activity

The New Basic Education and Whole School Reform:A Chinese Experience

在线全文

学校读者我要写书评

暂无评论

Frontiers of Education in China 2013年第4期8卷 576-595页

作者： Yuhua BU jiacheng li Institute of Schooling Reform and Development East China Normal UniversityShanghai 200062China

Since the 1980s,China has entered an era of transformation which has extended its reach to education and school ***“New Basic Education”(NBE)was born in this era and implemented by the East China Normal University together with schools around the *** aims at nurturing the active,healthy development of a new generation of Chinese people,focusing on classroom teaching and reform,and life practice within the classroom,as well as a reconstruction of school management.A breakthrough has been made with the development of a system that is suitable for the practice of education in China.

关键词： transformational school reform the New Basic Education(NBE) Ye Lan

Nanoscale engineering of conducting polymers for emerging applications in soft electronics

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano Research 2021年第9期14卷 3112-3125页

作者： Tao Wang Yiwen Bao Mengdi Zhuang jiacheng li Juncheng Chen Hangxun Xu Hefei National Laboratory for Physical Sciences at the Microscale CAS Key Laboratory of Soft Matter ChemistryDepartment of Polymer Science and EngineeringUniversity of Science and Technology of ChinaHefei 230026China

Soft electronics featuring exceptional mechanical compliance and excellent electrical performance hold great promise for applications in soft robotics,artificial intelligence,bio-integrated electronics,and wearable *** stretchable and conductive materials are crucial for soft electronics,enabling large-area and scalable fabrication,high device density,and good mechanical *** polymers are inherently stretchable and *** can be precisely synthesized from vastly available building blocks,and thus they provide a fruitful platform for fabricating soft ***,amorphous bulk-phase conducting polymers typically exhibit poor mechanical and electrical ***,it is highly desirable to develop novel engineering approaches to overcome the intrinsic limitations of conducting *** recent years,numerous engineering strategies have been developed to enhance their performances in soft electronic devices via constructing various *** this review,we first summarize several unique methodologies to fabricate conducting polymer-based *** then discuss how nanoscale engineering approaches can improve several crucial parameters,including electrical conductivity,stretchability,sensitivity,and self-healing property of conducting ***,we also discuss device-level integration of conducting polymer-based nanostructures with other materials for applications in skin-inspired electronics and bio-integrated ***,we provide perspectives on challenges and future directions in engineering nanostructured conducting polymers for soft electronics.

关键词： conducting polymers semiconducting polymers soft electronics nanostructures stretchable electronics