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Comparison of stratospheric evolution during the major sudden stratospheric warming events in 2018 and 2019

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Earth and Planetary Physics 2020年第5期4卷 493-503页

作者： Zheng Ma Yun Gong ShaoDong Zhang jiahui luo QiHou Zhou ChunMing Huang KaiMing Huang School of Electronic Information Wuhan UniversityWuhan 430072China State Key Laboratory of Space Weather Chinese Academy of SciencesBeijing 100190China Key Laboratory of Geospace Environment and Geodesy Ministry of EducationWuhan 430079China State Key Laboratory of Information Engineering in Surveying Mapping and Remote SensingWuhan UniversityWuhan 430079China Electrical and Computer Engineering Department Miami UniversityOxfordOhio 45056USA

Using Modern-Era Retrospective analysis for Research and Applications,Version 2(MERRA-2)data in the northern hemisphere at the 10 hPa level,we compared the stratospheric evolution of temperature and geopotential height during two major sudden stratosphere warming events(SSWs)that occurred in the Arctic winter of 2018 and *** the prewarming period,poleward temperature-enhanced regions were mainly located around 120°E with a displaced vortex and around 120°E and 60°W with splitting *** evolution of geopotential height indicated that these temperature-enhanced regions were both on the western side of high-latitude *** the postwarming period,the polar vortex turned from splitting to displacement in the 2018 SSW but from displacement to splitting in the 2019 *** transitions were observed over the Atlantic region,which may have been caused by anticyclones moving through the polar *** findings revealed that the evolution of the anticyclone is important during SSWs and is closely related to temperature-enhanced regions in the prewarming periods and to transitions of the polar vortices in postwarming periods.

关键词： sudden stratosphere warming transitions of the polar vortex anticyclone Atlantic region

Recent progress in high-loading single-atom catalysts and their applications

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Industrial Chemistry & Materials

Industrial Chemistry & Materials 2023年第4期1卷 486-500页

作者： jiahui luo Geoffrey I.N.Waterhouse Lishan Peng Qingjun Chen Key Laboratory of Rare Earths Chinese Academy of SciencesGanjiang Innovation AcademyChinese Academy of SciencesGanzhou 341000China School of Rare Earths University of Science and Technology of ChinaHefei 230026P.R.China School of Chemical Sciences The University of AucklandAuckland 1142New Zealand

Single-atom catalysts(SACs)attract significant attention owing to their high catalytic activity,high metal atom utilization efficiency,and well-defined and configurable active ***,achieving single-atom dispersion of active metals at high metal loadings remains challenging,limiting the performance of SACs in many practical ***,we provide a comprehensive review of recent methods developed for synthesizing high-loading SACs,critically exploring their advantages,limitations,and wider ***,we showcase the benefits of high-loading SACs in the oxygen reduction reaction(ORR),water electrolysis,photocatalytic hydrogen production and CO *** great recent progress has been made in the synthesis of high loading SACs,simple and universal routes that allowed the preprogrammed preparation of single metal and multi-metal SACs with specific metal coordination need to be discovered.

关键词： Single atom catalyst High-loading Synthesis methods ORR Water electrolysis CO oxidation

Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice

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Journal of Genetics and Genomics 2024年第4期51卷 407-418页

作者： Yaling Wang Xueying Huang Guoying Sun Jingwen Chen Bangguo Wu jiahui luo Shuyan Tang Peng Dai Feng Zhang Jinsong Li Lingbo Wang Shanghai Key Laboratory of Metabolic Remodeling and Health Institute of Metabolism and Integrative BiologyFudan UniversityShanghai 200438China Institute of Reproduction and Development Obstetrics and Gynecology HospitalFudan UniversityShanghai 200011China Shanghai Key Laboratory of Maternal and Fetal Medicine Clinical and Translational Research Center of Shanghai First Maternity and Infant HospitalFrontier Science Center for Stem Cell ResearchSchool of Life Sciences and TechnologyTongji UniversityShanghai 200092China State Key Laboratory of Cell Biology CAS Center for Excellence in Molecular Cell ScienceShanghai Institute of Biochemistry and Cell BiologyChinese Academy of SciencesShanghai 200031China

During spermiogenesis,haploid spermatids undergo dramatic morphological changes to form slender sperm flagella and cap-like acrosomes,which are required for successful *** deformities in flagella cause a male infertility syndrome,multiple morphological abnormalities of the flagella(MMAF),while acrosomal hypoplasia in some cases leads to sub-optimal embryonic developmental ***,evidence regarding the occurrence of acrosomal hypoplasia in MMAF is ***,we report the generation of base-edited mice knocked out for coiled-coil domain-containing 38(Ccdc38)via inducing a nonsense mutation and find that the males are *** Ccdc38-KO sperm display acrosomal hypoplasia and typical MMAF *** find that the acrosomal membrane is loosely anchored to the nucleus and fibrous sheaths are disorganized in Ccdc38-KO *** analyses reveal that Ccdc38 knockout causes a decreased level of TEKT3,a protein associated with acrosome biogenesis,in testes and an aberrant distribution of TEKT3 in *** finally show that intracytoplasmic sperm injection overcomes Ccdc38-related *** study thus reveals a previously unknown role for CCDC38 in acrosome biogenesis and provides additional evidence for the occurrence of acrosomal hypoplasia in MMAF.

关键词： Acrosomal hypoplasia Multiple morphological abnormalities of the flagella(MMAF) Infertility Sperm motility Asthenoteratozoospermia Disease modeling

Associations between blood glucose and early- and late-onset colorectal cancer: evidence from two prospective cohorts and Mendelian randomization analyses

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Journal of the National Cancer Center

Journal of the National Cancer Center 2024年第3期4卷 241-248页

作者： Chenyu luo jiahui luo Yuhan Zhang Bin Lu Na Li Yueyang Zhou Shuohua Chen Shouling Wu Qingsong Zhang Min Dai Hongda Chen Department of Cancer Epidemiology National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Center for Prevention and Early Intervention National Infrastructures for Translational MedicineInstitute of Clinical MedicinePeking Union Medical College HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Cardiology Department Kailuan General HospitalTangshanChina Department of General Surgery Kailuan General HospitalTangshanChina

Background: The incidence of early-onset colorectal cancer (EOCRC), which exhibits differential clinical, patho- logical, and molecular features compared to late-onset CRC (LOCRC), is rising globally. The potential differential effects of blood glucose on EOCRC compared to LOCRC have not been investigated. Methods: This study analyzed 374,568 participants from the UK Biobank cohort and 172,809 participants from the Kailuan cohort. The linear associations between blood glucose and EOCRC/LOCRC were estimated using Cox regression models. Restricted cubic spline (RCS) analysis and non-linear Mendelian randomization (MR) analysis using a 70-SNPs genetic instrument for fasting glucose were used to explore the potential non-linear associations. Results: Participants in the highest quintile of blood glucose had higher overall CRC risk compared to the lowest quintile (HR = 1.10 in the UK Biobank cohort, 95% CI: 1.01-1.21, P -trend = 0.012;HR = 1.23 in the Kailuan cohort, 95% CI: 1.01-1.51, P -trend = 0.036). Elevated glucose ( > 7.0 mmol/L) was more strongly associated with increased risk of EOCRC (HR = 1.61, 95% CI: 1.07-2.44) than with LOCRC (HR = 1.14, 95% CI: 1.02-1.27) in the UK Biobank cohort ( P- heterogeneity = 0.014). Elevated glucose ( > 7.0 mmol/L) was associated with increased risk of LOCRC (HR = 1.25, 95% CI: 1.04-1.65) in the Kailuan cohort as well. There was no evidence for non-linear associations between blood glucose and risks of EOCRC/LOCRC. Conclusions: This study showed a positive association between blood glucose and CRC risk in a dose-response manner, particularly for EOCRC, suggesting that tighter glucose control should be a priority for younger age groups.

关键词： Colorectal cancer Early-onset colorectal cancer Glucose Mendelian randomization Cancer prevention

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地铁空气微生物研究进展

应用与环境生物学报 2018年第4期24卷 934-940页

作者：罗佳慧王虹陈玲同济大学环境科学与工程学院污染控制与资源化研究国家重点实验室

地铁已发展成为现代城市中最重要的交通工具之一,由于其环境的特殊性（相对封闭、人流量大等）,空气较易受微生物污染,对公众健康构成潜在威胁.通过比较多种空气微生物采样和分析方法,发现主动采样和基于聚合酶链式反应（Polymerase cha... 详细信息

地铁已发展成为现代城市中最重要的交通工具之一,由于其环境的特殊性（相对封闭、人流量大等）,空气较易受微生物污染,对公众健康构成潜在威胁.通过比较多种空气微生物采样和分析方法,发现主动采样和基于聚合酶链式反应（Polymerase chain reaction,PCR）的分子生物学分析方法如16S rRNA基因测序、宏基因组学及定量PCR技术可为地铁空气微生物的污染特征提供更为准确、全面和细致的信息;通过分析全球范围内不同地区地铁空气微生物文献,发现地铁空气微生物的分布特征随时间和空间可发生较大变化,影响地铁内空气中细菌和真菌浓度及种类的主要因素包括环境温度、相对湿度、二氧化碳浓度、人流量、屏蔽门、通风系统等.建议尽快建立基于分子生物学分析的标准化采样和分析方法,获得地铁空气微生物污染水平的基线数据,并建立空气中致病菌浓度与人体健康风险的相关性.

关键词：地铁空气微生物主动采样分子生物学分布特征影响因素

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湍流热对流的高效并行直接求解方法

计算物理 2017年第6期34卷 651-656页

作者：包芸叶孟翔罗嘉辉中山大学力学系广州510275

结合泊松方程直接求解的PDD算法,创建二维湍流热对流DNS模拟的并行直接求解方法(PDM-DNS).在"天河二号"超级计算机上完成高Ra数湍流热对流大规模DNS计算,计算效果令人惊喜,实现了一年前难以达到的计算规模.高分辨率的湍流热对流计算结... 详细信息

结合泊松方程直接求解的PDD算法,创建二维湍流热对流DNS模拟的并行直接求解方法(PDM-DNS).在"天河二号"超级计算机上完成高Ra数湍流热对流大规模DNS计算,计算效果令人惊喜,实现了一年前难以达到的计算规模.高分辨率的湍流热对流计算结果显示,不同高Ra数的湍流热对流流动状态完全不同.为高Ra数湍流热对流大规模并行计算和数值模拟研究提供了有价值的计算方法.

关键词： Rayleigh-Bénard热对流湍流并行计算 PDM-DNS

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纯电动汽车动力总成悬置系统隔振性能研究

中国工程机械学报 2021年第6期19卷 492-499页

作者：陈克骆嘉晖沈阳理工大学汽车与交通学院辽宁沈阳110159

为了研究纯电动汽车动力总成悬置的隔振性能,分别对纯电动汽车和燃油车进行道路试验。采用频谱分析法对比了纯电动车和燃油车的频域特性,结合了悬置隔振率和车内振动响应,明确了悬置刚度对悬置隔振的影响。结果表明:纯电动汽车动力总成... 详细信息

为了研究纯电动汽车动力总成悬置的隔振性能,分别对纯电动汽车和燃油车进行道路试验。采用频谱分析法对比了纯电动车和燃油车的频域特性,结合了悬置隔振率和车内振动响应,明确了悬置刚度对悬置隔振的影响。结果表明:纯电动汽车动力总成产生的振幅小,频率范围广,降低橡胶悬置的刚度对动力总成产生的高频振动隔振效果好,但550 Hz以下范围内隔振效果较差,同时造成了车内7.5 Hz以下的低频振动明显。为保证车内乘员舒适性,纯电动汽车动力总成悬置应在满足550 Hz以下频段隔振的前提下兼顾高频段隔振。

关键词：纯电动汽车动力总成悬置频谱分析隔振率刚度

2013年平流层爆发性增温期间高纬电离层半日潮汐波研究

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地球物理学报 2022年第4期65卷 1185-1196页

作者：罗嘉辉龚韵马铮张绍东黄春明武汉大学电子信息学院武汉430072 地球空间环境与大地测量教育部重点实验室武汉430072 武汉大学测绘遥感信息工程国家重点实验室武汉430072

基于Sondrestrom站(67°N,51°W)非相干散射雷达观测数据,研究了2013年平流层爆发性增温(SSW)事件发生后高纬地区电离层F层和E层半日潮汐波.同时,对1月非SSW发生期间和不同太阳活动期间高纬电离层中的半日潮汐波进行了统计分析,并和2013... 详细信息

基于Sondrestrom站(67°N,51°W)非相干散射雷达观测数据,研究了2013年平流层爆发性增温(SSW)事件发生后高纬地区电离层F层和E层半日潮汐波.同时,对1月非SSW发生期间和不同太阳活动期间高纬电离层中的半日潮汐波进行了统计分析,并和2013年SSW事件发生后的结果进行了比较.研究发现,SSW发生后F层经向风中的半日潮汐波有显著增强,其振幅大于80 m·s^(-1)的时间持续了至少60 h,最大值达到109 m·s^(-1).在180~330 km范围内,半日潮汐波振幅平均大了24 m·s^(-1).在E层高度上,经向风中的半日潮汐波也在SSW发生后迅速增强,最大值达到109 m·s^(-1),在108~117 km范围内,其振幅平均大了33 m·s^(-1).在E层纬向风中,半日潮汐波振幅在120 km处连续超过36 h的时间内大于70 m·s^(-1),最大值达到92 m·s^(-1).不同太阳活动期间的半日潮汐波统计结果显示,和低太阳活动期间相比,高太阳活动期间半日潮汐波在F层和E层平均增强14 m·s^(-1).这明显小于SSW期间24和33 m·s^(-1)的增幅,表明高太阳活动不是2013年SSW期间高纬电离层半日潮汐波增强的主要原因.我们的研究表明2013年高纬电离层半日潮汐波的增强很可能是受到SSW事件的影响.

关键词：平流层爆发性增温高纬电离层半日潮汐波非相干散射雷达

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《伤逝》:怨弃主题的非道德化叙事

广州大学学报（社会科学版） 2010年第9期9卷 76-81页

作者：罗嘉慧广州大学人文学院广东广州510006

《伤逝》超越了传统怨弃型作品对两性关系的简单是非道德判断,藉由始乱终弃模式,通过弃妇子君观照出中国男性文人的人格特质,审视其爱情心理特点和审美旨趣,其中不无鲁迅私人化体验。涓生对子君的爱本质上是对理想中的拯救者幻象的爱,... 详细信息

《伤逝》超越了传统怨弃型作品对两性关系的简单是非道德判断,藉由始乱终弃模式,通过弃妇子君观照出中国男性文人的人格特质,审视其爱情心理特点和审美旨趣,其中不无鲁迅私人化体验。涓生对子君的爱本质上是对理想中的拯救者幻象的爱,而他的被拯救是通过拯救(向子君启蒙)而获得。涓生是文化复合型人格的文人经典形象,旧文人的"女儿"情结和新文学青年的启蒙精神的双重价值观使他成为中国爱情文学史上的独特的真诚负心郎。

关键词：《伤逝》始乱终弃女儿情结