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Brain-inspired Intelligent Robotics:Theoretical Analysis and Systematic Application

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Machine Intelligence Research 2023年第1期20卷 1-18页

作者： Hong Qiao ya-Xiong Wu Shan-Lin Zhong Pei-Jie Yin jia-Hao Chen The State Key Laboratory of Management and Control for Complex System Institute of AutomationChineseAcademyof SciencesBeijing100190China School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China Chinese Academy of Science Center for Excellence in Brain Science and Intelligence Technology Shanghai 200031China School of Mechanical Engineering University of Science and Technology BeijingBeijing 100083China

Traditional joint-link robots have been widely used in production lines because of their high precision for single *** the development of the manufacturing and service industries,the requirement for the comprehensive performance of robotics is *** types of bio-inspired robotics have been investigated to realize human-like motion control and manipulation.A study route from inner mechanisms to external structures is proposed to imitate humans and animals *** this idea,a brain-inspired intelligent robotic system is constructed that contains visual cognition,decision-making,motion control,and musculoskeletal *** paper reviews cutting-edge research in brain-inspired visual cognition,decision-making,motion control,and musculoskeletal *** software systems and a corresponding hardware system are established,aiming at the verification and applications of next-generationbrain-inspired musculoskeletal robots.

关键词： Brain-inspired intelligent robot software and hardware decision making muscle control cognitive intelligence.

Assessments on surface water resources and their vulnerability and adaptability in China

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Advances in Climate Change Research 2020年第4期11卷 381-391页

作者： QIN jia DINg Yong-jian ZHAO Qiu-Dong WANg Shao-Ping CHANg ya-Ping State Key Laboratory of Cryospheric Sciences Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China Key Laboratory of Eco-Hydrology Inland River Basin Northwest Institute of Eco-Environment and ResourcesChinese Academy of SciencesLanzhou730000China University of Chinese Academy of Sciences Beijing100049China

A clear understanding of the changes of water resources under the background of environmental changes is of great significance for scientific management and utilization of water resources in *** study systematically analyzed the spatialetemporal variations of surface water resources in China since *** vulnerability in current(2010s)and its trends from 2000 to late-2010s in different regions of China were also *** addition,the correspondingly adaptive measures to counter regional risks to water resources were *** concluded that the runoff of major rivers had been decreasing in eastern China and increasing in western China during *** the arid area of Northwest China,the alpine runoff has shown an overall upward trend since the late-1990s/early-2000s,with a 10%-25% increase caused by the increase of glacial meltwater and *** the runoff of each hydrological station in the 2000s-2010s was 34.7% lower than that in the 1950se2010s on *** increases in precipitation and glacial meltwater with global warming caused a rapid expansion of lakes in the Qinghai-Tibet Plateau and Xinjiang,thus leading to an increase in total area and water quantity of lakes in China from 1995 to *** mean contribution rates of climate change and human activity to runoff change in river basins of China were 53.5% and 46.5%,respectively,during the period of *** driving factor of runoff change in many river basins has gradually changed from climate change(1950s-2000)to human activity(2000-2018).During 2000-2018,the contributions of human activities to runoff change were 50%-80% in major rivers of eastern *** vulnerability in most areas of Northwest China and North China is generally high,with the vulnerability index greater than ***,in Northeast,East,South,and Central China,it is lower or not *** Southwest China,the vulnerability varies greatly with Yunnan and Sichuan relatively low while Chon

关键词： Runoff change Lake area Surface water vulnerability Adaptation measures China

Synthesis of tanshinoneⅡA analogues and their inhibitory activities against Cdc25 phosphatases

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Chinese Chemical Letters 2009年第12期20卷 1461-1464页

作者： Wei gang Huang Jing ya Li Yu Luo jia Li Wei Lu Department of Chemistry East China Normal University Shanghai 200062 China The National Center for Drugs Screening Shanghai Institute ofMateria Medica SIBS Chinese Academy of Sciences Shanghai 201203 China

Two series of tanshinone ⅡA derivatives were synthesized and evaluated for their antitumor activities as Cdc25 phosphatase inhibitors. Most of them demonstrated potent Cdc25 inhibitory activity and powerful cytotoxicity against A549 tumor cell line, producing IC50 values in very low micromolar range. At last, the preliminary SAR was discussed.

关键词： Tanshinone ⅡA Cdc25 phosphatases Synthesis Antitumor

Expression and functional characterization of platelet-derived growth factor receptor-like gene

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World Journal of gastroenterology 2010年第12期16卷 1465-1472页

作者： guo, Feng-Jie Zhang, Wei-jia Li, ya-Lin Liu, yan Li, Yue-Hui Huang, jian Wang, jia-jia Xie, Ping-Li Li, guan-Cheng Cent S Univ Xiangya Sch Med Canc Res Inst Changsha 410078 Hunan Peoples R China

AIM:To investigate the role of platelet-derived growth factor receptor-like gene(PDgFRL)in the anti-cancer therapy for colorectal cancers(CRC).METHODS:PDgFRL mRNA and protein levels were measured by reverse transcription-polymerase chain reaction(RT-PCR)and immunohistochemistry in CRC and colorectal normal *** prokaryotic expression vector was carried out in Escherichia coli(***),and purified by immobilized metal affinity *** effect of PDgFRL protein on CRC HCT-116 cells was detected by 3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide(MTT),clone counting,cell cycle,and wound healing ***:Both RT-PCR and immunohistochemistry showed that the expression of PDgFRL in colorectal normal tissues was higher than in cancer *** pET22b-PDgFRL prokaryotic expression vector was successfully expressed in ***,and the target protein was expressed in the form of inclusion *** purification and refolding,recombinant human PDgFRL(rhPDgFRL)could efficiently inhibit the proliferation and invasion of CRC HCT-116 cells detected by MTT,clone counting and wound healing ***,rhPDgFRL arrested HCT-116 cell cycling at the g0/g1 ***:PDgFRL is a potential gene for application in the anti-cancer therapy for CRC.

关键词： Platelet-derived growth factor receptorlike Colorectal cancer Prokaryotic expression Reverse transcription-polymerase chain reaction Immunohistochemistry

growth and characterization of ZnTe single crystal via a novel Te flux vertical Bridgman method

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Rare Metals 2021年第4期40卷 858-864页

作者： Min Jin Wen-Hui ya.g Xiang-Hu Wang Rong-Bin Li ya-Dong Xu jia-Yue Xu College of Materials Shanghai Dianji UniversityShanghai 201306China State Key Laboratory of Solidification Processing Northwestern Polytechnical UniversityXi’an 710072China School of Materials Science and Engineering Shanghai Institute of TechnologyShanghai 201418China

In this work,an Ⅱ-Ⅵ group semiconductor zinc telluride(ZnTe) single crystal is prepared by a novel vertical Bridgman method using Te as *** initial mole ratio of Zn/Te=3:7 is designed for raw material *** polycrystalline combined with rich Te is effectively fabricated through rocking technique at 1100℃.A Φ 25 mm × 65 mm ZnTe boule is successfully grown under a~40 ℃·cm^(-1) temperature gradient with a growth speed of 5 mm·day^(-1).The as-grown ZnTe crystal has a standard 1:1 stoichiometric ratio and pure F43 m phase *** maximum transmittance perpendicular to(110) plane is about 64%,and the band gap(E_(g)) is tested to be 2.225 ***(THz) examination results demonstrate that the time of the highest THz signal is around 17 ps and the frequency of the highest THz transmission is about 0.78 THz,implying that the ZnTe crystal grown by the present Te flux vertical Bridgman method has a good feasibility for THz application.

关键词： ZnTe crystal Te flux Vertical Bridgman method Terahertz property

Effects of intrinsic and extrinsic noises on transposons kinetics

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Chinese Physics B 2018年第3期27卷 153-160页

作者： Alssadig A M Yousif Lulu Lu Mengyan ge Ying Xu ya jia Institute of Biophysics and Department of Physics Central China Normal University Wuhan 430079 China

The absolute concentration robustness （ACR） steady state of a biochemical system can protect against changing a large concentration of the system＇s components. In this paper, a minimal model of autonomous-nonautonomous transposons driven by intrinsic and extrinsic noises is investigated. The effects of intrinsic and extrinsic noises on ACR steady state of the transposons kinetics are studied by numerical simulations. It is found that the predator-prey-like oscillations around the ACR steady state are induced by the intrinsic or extrinsic noises. Comparing with the case of intrinsic noises, the extrinsic noises can inhibit the amplitude of oscillations of transposon kinetics. To characterize the predator-prey-like oscillations, we calculate the probability distributions and the normalized correlation functions of a system in the stability domain. With the increasing of noise intensity, the peak of the probability distribution is shifted from the ACR steady state to the trivial steady state. The normalized autocorrelation and cross-correlation functions indicate that the state of the predator-prey oscillator is transmitted to 50 successive generations at least.

关键词： stability noises oscillation transposon kinetics

Spillover of international crude oil prices on China's refined oil wholesale prices and price forecasting:Daily-frequency data of private enterprises and local refineries

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Petroleum Science 2022年第3期19卷 1433-1442页

作者： Xun-Zhang Pan Xi-Ran Ma Li-Ning Wang ya-Chen Lu jia-Quan Dai Xiang Li School of Economics and Management China University of PetroleumBeijing 102249China Economics&Technology Research Institute China National Petroleum CorporationBeijing 100724China Key Laboratory of Oil and gas Market Simulation and Price Forecasting China National Petroleum CorporationBeijing 100724China Institue of Energy Peking UniversityBeijing 100080China

Compared with retail prices of state-owned companies used in almost all existing studies,China’s refined oil wholesale prices of private enterprises and local refineries are more affected by the market and better reflect the real supply-demand *** the first time,this paper applies own-monitored dailyfrequency wholesale prices of China’s private enterprises and local refineries during 2013-2020 to derive spillover effects of international crude oil prices on China’s refined oil prices through the VAR-BEKKgARCH(vector autoregression-Baba,Engle,Kraft,and Kroner-generalized autoregressive conditional heteroscedasticity)model,and then tries to forecast wholesale prices through the PCA-BP(principal component analysis-back propagation)neural network *** show that international crude oil prices have significant mean spillover and volatility spillover effects on China’s refined oil wholesale *** in crude oil prices are the granger cause of changes in refined oil wholesale *** the improvement of China’s oil-pricing mechanism in 2016,the volatility spillover from the international crude oil market to China’s refined oil market gradually increases,and the BRENT price variation has an increasing impact on the refined oil wholesale price *** PCA-BP model could serve as a candidate tool for forecasting China’s refined oil wholesale prices.

关键词： Own-monitored daily-frequency data Refined oil wholesale prices Spillover effects VAR-BEKK-gARCH PCA-BP neural Network

Preparation and radar-absorbing properties of Al2O3/TiO2/Fe2O3/Yb2O3 composite powder

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International Journal of Minerals,Metallurgy and Materials 2017年第2期24卷 216-221页

作者： Yi-fan Zhang Zhen Ji Ke Chen Cheng-chang jia Shan-wu ya.g Meng-ya Wang School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

Al2O3/TiOe/FeeO3/Yb2O3 composite powder was synthesized via the sol-gel method. The structure, morphology, and ra- dar-absorption properties of the composite powder were characterized by transmission electron microscopy, X-ray diffraction analysis and RF impedance analysis. The results show that two types of particles exist in the composite powder. One is irregular flakes （100-200 rim） and the other is spherical A1203 particles （smaller than 80 rim）. Electromagnetic wave attenuation is mostly achieved by dielectric loss. The maximum value of the dissipation factor reaches 0.76 （at 15.68 gHz） in the frequency range of 2-18 gHz. The electromagnetic absorption of waves covers 2-18 gHz with the matching thicknesses of 1.5-4.5 mm. The absorption peak shifts to the lower-frequency area with increas- ing matching thickness. The effective absorption hand covers the frequency range of 2.16-9.76 gHz, and the maximum absorption peak reaches -20.18 dB with a matching thickness of 3.5 mm at a frequency of 3.52 gHz.

关键词： nanocomposites radar absorbing materials sol-gel processing electromagnetic wave attenuation

Poly(N-isopropylacrylamide)-grafted Dual Stimuli-responsive Filter Paper for Protein Separation

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Chinese Journal of Polymer Science 2015年第7期33卷 1048-1057页

作者： Qi-jia-yu Wu Rui Wang Ying Zhou ya-qin Huang Raja ghosh 陈晓农 Beijing Laboratory of Biomedical Materials Beijing University of Chemical Technology Department of Chemical Engineering Mc Master University 1280 Main Street West

Thermal and salt dual stimuli-responsive filter-paper-based membranes were prepared by UV-induced grafting of NIPAM-based polymers on paper surface. The grafting ratio could be controlled by monomer concentration during grafting polymerization. The results from pressure drop measurement of the mobile phase flowed cross the membrane demonstrate that an appropriate grafting ratio would be 8%-10%. Protein adsorption on the membrane through hydrophobic interaction could be promoted by increasing temperature and lyotropic salt concentration. The effect of grafted polymer structure on protein binding performance was studied. Filter paper grafted with NIPAM-based branched copolymer consisting of hydrophobic monomer moieties shows ten times higher protein binding capacity than that of the original filter paper. The separation of plasma proteins using the dual stimuli-responsive membrane was examined to demonstrate feasible application for hydrophobic interaction chromatographic separation of proteins.

关键词： N-isopropyl acrylamide Filter paper Surface grafting Stimuli-responsive hydrophobic transition Protein separation