咨询与建议

限定检索结果

文献类型

  • 101,340 篇 期刊文献
  • 777 篇 会议
  • 1 册 图书

馆藏范围

  • 102,117 篇 电子文献
  • 1 种 纸本馆藏

日期分布

学科分类号

  • 45,336 篇 工学
    • 6,499 篇 材料科学与工程(可...
    • 5,670 篇 化学工程与技术
    • 4,028 篇 机械工程
    • 3,032 篇 计算机科学与技术...
    • 3,017 篇 电气工程
    • 2,402 篇 软件工程
    • 2,386 篇 仪器科学与技术
    • 2,309 篇 食品科学与工程(可...
    • 2,203 篇 土木工程
    • 2,123 篇 电子科学与技术(可...
    • 2,117 篇 环境科学与工程(可...
    • 2,085 篇 动力工程及工程热...
    • 1,858 篇 控制科学与工程
    • 1,848 篇 水利工程
  • 35,449 篇 医学
    • 19,383 篇 临床医学
    • 5,651 篇 中西医结合
    • 3,794 篇 药学(可授医学、理...
    • 3,775 篇 公共卫生与预防医...
    • 3,230 篇 中药学(可授医学、...
    • 2,788 篇 基础医学(可授医学...
    • 2,307 篇 医学技术(可授医学...
    • 2,073 篇 中医学
  • 13,674 篇 理学
    • 3,302 篇 化学
    • 3,045 篇 生物学
    • 1,930 篇 生态学
  • 13,619 篇 农学
    • 3,892 篇 作物学
    • 2,670 篇 农业资源与环境
  • 5,442 篇 管理学
    • 2,266 篇 管理科学与工程(可...
    • 1,981 篇 公共管理
  • 2,968 篇 教育学
    • 2,347 篇 教育学
  • 1,799 篇 经济学
  • 950 篇 法学
  • 800 篇 文学
  • 476 篇 艺术学
  • 318 篇 历史学
  • 259 篇 军事学
  • 148 篇 哲学

主题

  • 627 篇 影响因素
  • 583 篇 数值模拟
  • 482 篇 预后
  • 472 篇 产量
  • 402 篇 儿童
  • 386 篇 大鼠
  • 324 篇 危险因素
  • 276 篇 力学性能
  • 250 篇 诊断
  • 229 篇 糖尿病
  • 222 篇 应用
  • 208 篇 磁共振成像
  • 206 篇 细胞凋亡
  • 205 篇 治疗
  • 202 篇 综述
  • 186 篇 免疫组织化学
  • 179 篇 凋亡
  • 177 篇 合成
  • 174 篇 meta分析
  • 173 篇 玉米

机构

  • 688 篇 四川大学
  • 647 篇 中国科学院大学
  • 634 篇 北京大学
  • 559 篇 吉林大学
  • 554 篇 上海交通大学
  • 520 篇 清华大学
  • 493 篇 北京中医药大学
  • 481 篇 天津大学
  • 458 篇 浙江大学
  • 428 篇 中南大学
  • 406 篇 西北农林科技大学
  • 391 篇 中国矿业大学
  • 378 篇 解放军总医院
  • 366 篇 同济大学
  • 359 篇 西安交通大学
  • 357 篇 华中科技大学
  • 353 篇 大连理工大学
  • 349 篇 西南大学
  • 341 篇 哈尔滨工业大学
  • 335 篇 山东大学

作者

  • 1,063 篇 赵佳
  • 943 篇 刘佳
  • 647 篇 李佳
  • 417 篇 王佳
  • 314 篇 谢佳
  • 284 篇 赵静
  • 272 篇 赵勇
  • 252 篇 赵伟
  • 225 篇 陈佳
  • 208 篇 赵敏
  • 194 篇 赵亮
  • 171 篇 赵娜
  • 167 篇 赵磊
  • 165 篇 谢辉
  • 164 篇 赵军
  • 162 篇 赵鹏
  • 162 篇 赵嘉
  • 147 篇 贾伟
  • 144 篇 赵辉
  • 140 篇 张佳

语言

  • 95,107 篇 中文
  • 7,010 篇 英文
  • 1 篇 日文
检索条件"作者=Jia-zhao Xie"
102118 条 记 录,以下是1-10 订阅
排序:
A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimer-like pathology
收藏 引用
Signal Transduction and Targeted Therapy 2024年 第5期9卷 2324-2340页
作者: Xin Wang Qian Liu Hai-tao Yu jia-zhao xie Jun-ning zhao Zhi-ting Fang Min Qu Yao Zhang Ying Yang jian-Zhi Wang Department of Pathophysiology School of Basic MedicineKey Laboratory of Education Ministry of China/Hubei Province for Neurological DisordersTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Department of Fundamental Medicine Wuxi School of MedicineJiangnan UniversityWuxiJiangsu 214122China Hubei Provincial Key Laboratory for Applied Toxicology Hubei Provincial Center for Disease Control and PreventionHubei Provincial Academy of Preventive MedicineWuhan 430000China Endocrine Department of Liyuan Hospital Key Laboratory of Ministry of Education of China for Neurological DisordersTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430077China Co-innovation Center of Neuroregeneration Nantong UniversityNantong 226000China
Impaired brain glucose metabolism is an early indicator of Alzheimer’s disease(AD);however,the fundamental mechanism is *** this study,we found a substantial decline in isocitrate dehydrogenase 3β(IDH3β)levels,a cr... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting
收藏 引用
Neuroscience Bulletin 2019年 第4期35卷 724-734页
作者: Yao Zhang jia-zhao xie Xiang-Yang Xu Jun Hu Teng Xu Si Jin Shao-Juan Yang jian-Zhi Wang Endocrinology Department of Liyuan Hospital and Key Laboratory of the Ministry of Education of China for Neurological Disorders Tongji Medical College Huazhong University of Science and Technology Wuhan 430077 China Department of Pathophysiology School of Basic Medicine and the Collaborative Innovation Center for Brain Science Key Laboratory of the Ministry of Education of China for Neurological Disorders Tongji Medical College Huazhong University of Science and Technology Wuhan 430030 China Endocrinology Department Liyuan Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430077 China Radiology Department Liyuan Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430077 China
Hyperhomocysteinemia(Hhcy)is an independent risk factor for Alzheimer's disease(AD),and insulinresistance is commonly seen in patients with ***(Lir),a glucagon-like peptide that increases the secretion and sensitivity... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Protein Phosphatase 2A as a Drug Target in the Treatment of Cancer and Alzheimer's Disease
收藏 引用
Current Medical Science 2020年 第1期40卷 1-8页
作者: Hui WEI Hui-liang ZHANG jia-zhao xie Dong-li MENG Xiao-chuan WANG Dan KEI Ji ZENG Rong LIU Department of Pathophysiology Key Laboratory of Ministry of Education for Neurological DisordersSchool of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China Department of Clinic Laboratory Wuhan Fourth HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430030China
Protein phosphatase 2A(PP2A)is a major serine/threonine phosphatase which participates in the regulation of multiple cellular *** a confirmed tumor suppressor,PP2A activity is downregulated in tumors and its re-activa... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Understanding the local structure and thermophysical behavior of Mg-La liquid alloys via machine learning potential
收藏 引用
International Journal of Minerals,Metallurgy and Materials 2025年 第2期32卷 439-449页
作者: jia zhao Taixi Feng Guimin Lu National Engineering Research Center for Integrated Utilization of Salt Lake Resource East China University of Science and TechnologyShanghai 200237China Joint International Laboratory for Potassium and Lithium Strategic Resources East China University of Science and TechnologyShanghai 200237China
The local structure and thermophysical behavior of Mg-La liquid alloys were in-depth understood using deep potential molecular dynamic(DPMD) simulation driven via machine learning to promote the development of Mg-La a... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Correction:A positive feedback inhibition of isocitrate dehydrogenase 3β on paired-box gene 6 promotes Alzheimerlike pathology
收藏 引用
Signal Transduction and Targeted Therapy 2024年 第8期9卷 3537-3540页
作者: Xin Wang Qian Liu Hai-tao Yu jia-zhao xie Jun-ning zhao Zhi-ting Fang Min Qu Yao Zhang Ying Yang jian-Zhi Wang Department of Pathophysiology School of Basic Medicine Key Laboratory of Education Ministry of China/Hubei Province for Neurological Disorders Tongji Medical College Huazhong University of Science and Technology Wuhan China Department of Fundamental Medicine Wuxi School of Medicine Jiangnan University Wuxi Jiangsu 214122 China Co-innovation Center of Neuroregeneration Nantong University Nantong 226000 China Hubei Provincial Key Laboratory for Applied Toxicology Hubei Provincial Center for Disease Control and Prevention Hubei Provincial Academy of Preventive Medicine Wuhan 430000 China Endocrine Department of Liyuan Hospital Key Laboratory of Ministry of Education of China for Neurological Disorders Tongji Medical College Huazhong University of Science and Technology Wuhan 430077 China
After online publication of the article',the authors noticed that,owing to authors'oversight in layer placement within the illustration,Golgi staining images representing both the 5xFAD group and,the 5xFAD+IDH3β_grou... 详细信息
来源: 维普期刊数据库 维普期刊数据库 评论
Thickness and sp3 bond modulation of(Ti/tetrahedral amorphous carbon)_n multilayer coatings
收藏 引用
Tungsten 2025年 第1期7卷 152-160页
作者: Zhi-Jun xie jia-Lin Li Ling Gong Xiang-Li Zhong Hong-jia Song Jin-Bin Wang National-Provincial Laboratory of Special Function Thin Film Materials School of Materials Science and Engineering Xiangtan University
The durability of wear-resistant tetrahedral amorphous carbon(ta-C) coatings is intimately linked to their thickness and the concentration of *** enhance the lifespan of the coatings,we have prepared a multilayer co... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Engineering nanoparticle structure at synergistic Ru-Na interface for integrated CO2 capture and hydrogenation
收藏 引用
Journal of Energy Chemistry 2025年 第1期100卷 779-791页
作者: Hanzi Liu Ling Cen Xinlin xie Lei Liu zhao Sun Zhiqiang Sun Hunan Engineering Research Center of Clean and Low-Carbon Energy Technology School of Energy Science and Engineering Central South University
The development of dual functional material for cyclic CO2capture and hydrogenation is of great significance for converting diluted CO2into valuable fuels,but suffers from kinetic limitation and deactivation of adsorb... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Unraveling the significance of cobalt on transformation kinetics,crystallography and impact toughness in high-strength steels
收藏 引用
International Journal of Minerals,Metallurgy and Materials 2025年 第2期32卷 380-390页
作者: Yishuang Yu Jingxiao zhao Xuelin Wang Hui Guo Zhenjia xie Chengjia Shang Collaborative Innovation Center of Steel Technology University of Science and Technology BeijingBeijing 100083China School of Materials Science and Engineering Shanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory for Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China
This work reveals the significant effects of cobalt(Co)on the microstructure and impact toughness of as-quenched highstrength steels by experimental characterizations and thermo-kinetic *** results show that the Co-be... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论
Modular assembly of Co4-thiacalix[4]arene units and Keggin-type SiW12O40 for visible-light photothermal conversion
收藏 引用
Tungsten 2025年 第1期7卷 112-119页
作者: jia-Hui Li Qing zhao Dong-Ao Mao Kun Zhou Bao-Kuan Chen Yan-Feng Bi School of Petrochemical Engineering Liaoning Petrochemical University
The construction of metal-organic coordination clusters(MCCs) using modular secondary building units is an important method for preparing functional *** this study,two new MCCs modularly assembled from Keggin-type {... 详细信息
来源: 同方期刊数据库 同方期刊数据库 评论
Inhibiting SHP2 reduces glycolysis, promotes microglial M1 polarization, and alleviates secondary inflammation following spinal cord injury in a mouse model
收藏 引用
Neural Regeneration Research 2025年 第3期20卷 858-872页
作者: Xintian Ding Chun Chen Heng zhao Bin Dai Lei Ye Tao Song Shuai Huang jia Wang Tao You Department of Orthopedics The First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefeiAnhui ProvinceChina Department of Orthopedics Provincial Hospital Affiliated to Anhui Medical UniversityHefeiAnhui ProvinceChina
Reducing the secondary inflammatory response, which is partly mediated by microglia, is a key focus in the treatment of spinal cord injury. Src homology 2-containing protein tyrosine phosphatase 2(SHP2), encoded by PT... 详细信息
来源: 维普期刊数据库 维普期刊数据库 同方期刊数据库 同方期刊数据库 评论