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过表达神经调节蛋白1的人羊膜间充质干细胞促进小鼠皮肤创面愈合

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中国组织工程研究 2025年第7期29卷 1343-1349页

作者：胡涛涛刘兵陈诚殷宗银阚道洪倪杰叶凌霄郑祥兵严敏邹勇四川大学华西医院宜宾医院四川省宜宾市644000

背景:神经调节蛋白1具有促进细胞增殖、分化以及血管生长等特性。人羊膜间充质干细胞是组织工程领域重要的种子细胞,已被证实参与组织修复及再生过程。目的:构建过表达神经调节蛋白1的人羊膜间充质干细胞,探究其增殖、迁移能力以及对创... 详细信息

背景:神经调节蛋白1具有促进细胞增殖、分化以及血管生长等特性。人羊膜间充质干细胞是组织工程领域重要的种子细胞,已被证实参与组织修复及再生过程。目的:构建过表达神经调节蛋白1的人羊膜间充质干细胞,探究其增殖、迁移能力以及对创面愈合的影响。方法:(1)体外分离培养人羊膜间充质干细胞并对其进行鉴定;(2)构建神经调节蛋白1过表达慢病毒,将人羊膜间充质干细胞分为空载组、神经调节蛋白1组、对照组,分别转染空载慢病毒、过表达神经调节蛋白1慢病毒,对照组不进行转染;(3)EdU实验检测各组细胞增殖能力,Transwell实验检测各组细胞迁移能力;(4)构建C57BL/6小鼠创面损伤模型,随机分成对照组、空载组和神经调节蛋白1组,每组8只,分别在创面局部多点均匀注射1 mL转染空载慢病毒或转染过表达神经调节蛋白1慢病毒的人羊膜间充质干细胞,对照组注射等量的生理盐水;(5)造模后1,7,14 d观察创面愈合情况,苏木精-伊红染色观察创面愈合组织学变化,免疫组化观察创面CD31的表达。结果与结论:(1)成功构建过表达神经调节蛋白1的人羊膜间充质干细胞,细胞内神经调节蛋白1的mRNA、蛋白表达较空载组明显上调(P<0.05);(2)过表达神经调节蛋白1促进了人羊膜间充质干细胞的迁移(P<0.01)和增殖(P<0.05);(3)过表达神经调节蛋白1的人羊膜间充质干细胞促进了小鼠创面愈合(P<0.05)和创面的血管生成(P<0.05)。结果表明,过表达神经调节蛋白1提高了人羊膜间充质干细胞的增殖和迁移能力,以及增强了促进创面愈合和创面血管生成的能力。

关键词：人羊膜间充质干细胞神经调节蛋白1 过表达细胞增殖细胞迁移小鼠创面愈合

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大气层外主动防御三维自适应滑模制导律

系统工程与电子技术 2015年第2期37卷 365-371页

作者：邹昕光周荻杜润乐刘佳琪哈尔滨工业大学电气工程及自动化学院黑龙江哈尔滨150001 哈尔滨工业大学航天学院黑龙江哈尔滨150001 试验物理与计算数学国家级重点实验室北京100076

针对提高弹道导弹中段突防成功概率问题,提出了主动防御滑模自适应制导律。首先,推导出目标、拦截导弹和防御导弹的三维相对运动方程。其次,基于三角拦截制导策略,利用Lyapunov稳定性理论设计了主动防御滑模自适应制导律(active defense... 详细信息

针对提高弹道导弹中段突防成功概率问题,提出了主动防御滑模自适应制导律。首先,推导出目标、拦截导弹和防御导弹的三维相对运动方程。其次,基于三角拦截制导策略,利用Lyapunov稳定性理论设计了主动防御滑模自适应制导律(active defense adaptive sliding mode guidance law,AD-ASMG)。该制导律能同时达到两个制导目标:防御导弹处在目标和拦截导弹视线上,保持三点共线;零化防御导弹对拦截导弹的视线转率。最后,针对开关式轨控发动机推力大小不可调节的问题,考虑了发动机动态特性,设计了精确的脉冲宽度调制(pulse width modulation,PWM)控制方法,获得可变的等效力,适应制导指令变化的要求。六自由度仿真结果表明了该制导律的有效性。

关键词：主动防御制导律滑模变结构控制脉冲宽度调制

A biomimetic robot crawling bidirectionally with load inspired by rock-climbing fish

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2022年第1期23卷 14-26页

作者： Jin-rong WANG Yong-xin XI Chen JI Jun zou State Key Laboratory of Fluid Power and Mechatronic Systems Zhejiang UniversityHangzhou310027China College of Electrical Engineering Zhejiang UniversityHangzhou310027China Institute of Marine Science and Technology Shandong UniversityQingdao266237China

Using a unique adhesive locomotion system,the rock-climbing fish(Beaufortia kweichowensis)adheres to submerged surfaces and crawls both forwards and backwards in torrential *** emulate this mechanism,we present a biomimetic robot inspired by the locomotion model of the rock-climbing *** prototype contains two anisotropic adhesive components with linkages connected to a linear *** anisotropic adhesive component consists of one commercial sucker and two retractable bioinspired fin *** fin components mimic the abduction and adduction of pectoral and pelvic fins through the retractable part to move up and *** robot prototype was tested on vertical and inverted surfaces,and worked *** results demonstrate that this novel system represents a new locomotion solution for surface movement without detachment from the substrate.

关键词： Fish kinematics Adhesive locomotion mechanism Fin rays motion Climbing model Bio-inspired robot

Research on Effect of Biolatex Surface Sizing on Paper Properties

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Paper And Biomaterials 2018年第2期3卷 24-31页

作者： Juan zou Tao Lin Sichuan Technology and Business College Dujiangyan Sichuang Province 611837 China Shaanxi Province Key Laboratory of Papermaking Technology and Specialty Paper Shaanxi University of Science and Technology Xi'an Shaanxi Province 710021 China

Biolatex, a new type of paper coating adhesive that has been developed in recent years, has mainly been used in pre-coating and middle coating, due to its advantages of decreasing the associated cost and pollution by partly replacing petro-latex. In this paper, application of biolatex as a surface sizing agent and effects of various factors, such as titanium dioxide addition, on the properties of the sized paper were compared. The results showed that, addition of titanium dioxide to biolatex could improve the whiteness, internal bond strength, and ink absorption. Furthermore, application of the No.4 biolatex resulted in better surface strength, bond strength, and ink absorption of the sized paper than application of polyvinyl alcohol.

关键词： biolatex polyvinyl alcohol (PVA) titanium dioxide surface sizing

A Study on the Acceptance of the English Translation of Romance of the Three Kingdoms by Overseas Readers Based on Python Data Analysis Technology

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Sino-US English Teaching 2023年第5期20卷 187-194页

作者： LIU Wei zou jianling University of Shanghai for Science and Technology ShanghaiChina

Paperless reading has become a prevalent trend among global readers,leading to the accumulation of vast amounts of reading data on numerous book *** offers new perspectives for studying translated *** paper utilizes Python-based data processing technology to collect and analyze reader reviews of Romance of the Three Kingdoms on Amazon and Goodreads,presenting trends in review volume,word cloud maps,and readers’emotional attitudes in a quantitative *** findings indicate that overseas readers generally exhibit a positive emotional tendency towards Romance of the Three Kingdoms and recognize its cultural ***,negative opinions do exist,focusing on aspects of the book’s quality,such as printing quality and *** results provide valuable insights for the foreign translation of canonical texts.

关键词： Romance of the Three Kingdoms readers’comment emotional analysis

A Novel Reassortant H2N3 Influenza Virus Isolated from China

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Biomedical and Environmental Sciences 2014年第4期27卷 240-249页

作者： LI Xiao Dan zou Shu Mei ZHANG Ye BAI Tian GAO Rong Bao ZHANG Xin WU Jie SHU Yue Long Chinese National Influuenza Center National Institute for Viral Disease Control and Prevention Chinese Center for Disease Control and Prevention Key Laboratory of Surveillance and Early warning on Infectious Disease Key Laboratory for Medical Virology National Health and family planning Commission Center for Disease Control and Prevention of Guangdong Province

Objective To analyze the genetic composition of a novel H2N3 virus isolate identified from a duck cage swab in a live poultry market （LPM） in 2009 in Guangdong province of China. Methods PCR-positive specimens were inoculated into embryonated chicken eggs and subtyped by conventional RT-PCR. All segments of the virus A/environment/Guangdong/2/2009 were sequenced, and phylogenetic trees were constructed and analyzed. Results The genes of this virus belong to Eurasian-lineage avian viruses. The virus is a reassortant with the HA gene from an H2N2 virus and the NA gene from an H5N3 virus. The PB1, PB2, and NP genes were from an H4N6 virus, the PA was from an H3N8 virus, the M gene was from an H1N3 virus, and the NS gene was from an H10N6 virus. Conclusion market. Its A novel avian-origin reassortant H2N3 influenza virus was detected in a live poultry potential impacts and evolution should be closely monitored.

关键词： Avian influenza Gene analysis H2N3

Oxidation process of lanthanum hexaboride ceramics

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Rare Metals 2002年第2期21卷 101-105页

作者： ZHENG Shuqi, MIN Guanghui, zou Zengda , YU Huashun, HAN jiande , and WANG Weiti School of Materials Science and Engineering, Shandong University, Jinan 250061, China School of Materials Science and Engineering Shandong University Jinan 250061

Oxidation process of lanthanum hexaboride (LaB_6) ceramic powderwas investigated. The laB_6 powder sma- ples were heated continuallyfrom room temperature to 1473 K at a heating rate of 10 k/min bydifferential scanning calorimetry. The oxidation tests were conductedat different exposure temeratures. The phases and morphologies of thesamples before and after exposure were analyzed by XRD and SEM. Itwas pointed out that before 1273 K, LaB_6 has high oxidationresistant ability, which was due to that the oxide layer hinders theoxygen diffusion from outer to the sur- face of Lab_6 grains.

关键词： lanthanum hexaboride oxidation mechanism ceramic

Geo-religion and China＇s Foreign Strategies

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China International Studies 2013年第1期33卷 49-65,2页

作者： Xu Yihua zou Lei Professor at School of International Relations and Public Affairs Fudan University a PhD candidate at School of International Relations and Public Affairs Fudan University.

In contemporary international politics, the ＂global resurgence of religion＂ and the ＂political awakening of religion＂ have increasingly become trans-regional and trans-national phenomena. At the same time, globalization has increased religion＇s impact on the international relations and domestic politics of all states. Religion is not only viewed as an ＂extension of politics in another form＂ but also as a resource competed for bv state in the international arena.

关键词：宗教国际政治地理中国全球范围国际关系全球化

氧化硼对苯乙烯原子转移自由基聚合的加速作用

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高等学校化学学报 2008年第11期29卷 2299-2302页

作者：林睿庄家明许锐赵军林华端邹友思厦门大学化学化工学院厦门361005

以2-溴丙酸乙酯为引发剂,溴化亚铜为催化剂,N,N,N′,N″,N″-五甲基二乙基三胺为配体,以氧化硼为加速剂,进行了苯乙烯原子转移自由基聚合的加速研究.发现氧化硼与引发剂比例为4时,加速效果最为明显,且对分子量的控制效果较好.在85℃时,... 详细信息

以2-溴丙酸乙酯为引发剂,溴化亚铜为催化剂,N,N,N′,N″,N″-五甲基二乙基三胺为配体,以氧化硼为加速剂,进行了苯乙烯原子转移自由基聚合的加速研究.发现氧化硼与引发剂比例为4时,加速效果最为明显,且对分子量的控制效果较好.在85℃时,添加该比例的氧化硼,苯乙烯在6 h的聚合转化率达到78.5%.在65,75及85℃条件下,加入氧化硼时体系的聚合反应动力学为一级反应,苯乙烯聚合速率分别为空白体系的1.82,1.54和1.5倍;聚合物的分子量可控,分子量分布窄,体系呈现明显的活性聚合特征.通过核磁共振谱对聚合物的结构进行了表征,证明氧化硼在整个聚合过程中只起加速作用,并不影响聚合机理和聚苯乙烯的结构.氧化硼价廉,有利于实现原子转移聚合的工业化.

关键词：氧化硼加速苯乙烯原子转移自由基聚合