检索结果-南通市图书馆

Journal of Iron and Steel Research International 2024年第3期31卷 767-777页

作者： Hong-bin Dai jian Miao jia-xin lin School of Materials Science and Engineering Harbin University of Science and TechnologyHarbin 150040HeilongjiangChina

The welding arc,as a carrier for the conversion of electrical energy to thermal energy,has a direct impact on the quality of welding by its properties and *** the tungsten inert gas(TIG)welding process under the condition of Ar-He alternating gas supply,the arc is alternately converted between Ar arc and He arc with an alternating gas supply cycle,which has obvious arc change *** FLUENT software was used to numerically simulate the characteristics of the TIG arc under the condition of alternating gas supply,and the arc temperature field,arc pressure,electric potential and current density distribution under the condition of alternating gas supply were *** with the real-time data of arc pressure measured by the water-cooled copper plate with holes,it is proved that the TIG arc has obvious dynamic characteristics under the condition of Ar-He alternating gas *** unique dynamic TIG arc acts on the 5A06 aluminum alloy weld,causing the molten pool to stir,resulting in uniform microstructure and grain refinement at the weld,and thereby improving the mechanical properties of the welded joint.

关键词： Alternating gas supply Grain refinement Numerical simulation Tungsten argon arc morphology Microstructure Mechanical property

Mechanism study of Cu(Ⅱ) adsorption from acidic wastewater by ultrasonic-modified municipal solid waste incineration fly ash

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Chemical Engineering 2024年第3期67卷 157-165页

作者： Shunda lin Yang Lu lin Zheng ling Long Xuguang jiang jianhua Yan State Key Laboratory of Clean Energy Utilization Institute for Thermal Power EngineeringZhejiang UniversityHangzhou 310027China Zhejiang University Qingshanhu Energy Research Center Hangzhou 310027China Hangzhou Xiaoshan Jinjiang Green Energy Co. Ltd.XiaoshanHangzhou 310000China

High concentrations of copper ions(Cu(Ⅱ)) in water will pose health risks to humans and the ecological environment. Therefore, this study aims to utilize ultrasonic-cured modified municipal solid waste incineration(MSWI) fly ash for Cu(Ⅱ) adsorption to achieve the purpose of “treating waste by waste.” The effects of p H, adsorption time, initial concentration, and temperature on the modified MSWI fly ash’s adsorption efficiency were systematically studied in this article. The adsorption performance of the modified MSWI fly ash can be enhanced by the ultrasonic modification. At pH = 2, 3 and 4, the adsorption capacity of the modified MSWI fly ash for Cu(Ⅱ) increased by 2.7, 1.9 and 1.2 times, respectively. Furthermore, it was suggested that the adsorption process of the modified MSWI fly ash can be better simulated by the pseudo-second-order kinetic model, with a maximum adsorption capacity calculated by the Langmuir model of 24.196 mg.g-1. Additionally, the adsorption process is spontaneous,endothermic, and chemisorption-dominated from the thermodynamic studies(ΔH and ΔS > 0, ΔG < 0).Finally, the enhanced adsorption performance of the modified MSWI fly ash for Cu(Ⅱ) may be attributed to electrostatic interaction and chelation effects.

关键词： Ultrasound MSWI fly ash Cu(Ⅱ) Wastewater Adsorption

Effect of Ellipsoidal Particle Shape on Tribological Properties of Lubricants Containing Nanoparticles

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Mechanical Engineering 2024年第4期37卷 231-242页

作者： ling Pan Zhi Li Yunhui Chen Guobin lin School of Advanced Manufacturing Fuzhou UniversityQuanzhou 362251FujianChina School of Mechanical Engineering and Automation Fuzhou UniversityFuzhou 350108FujianChina

Adding nanoparticles can significantly improve the tribological properties of ***,there is a lack of understanding regarding the influence of nanoparticle shape on lubrication *** this work,the influence of diamond nanoparticles(DNPs)on the tribological properties of lubricants is investigated through friction ***,the friction characteristics of lubricants regarding ellipsoidal particle shape are investigated using molecular dynamics(MD)*** results show that DNPs can drastically lower the lubricant's friction coefficientμfrom 0.21 to *** shearing process reveals that as the aspect ratio(α)of the nanoparticles approaches 1.0,the friction performance improves,and wear on the wall *** the same time,the shape of the nanoparticles tends to be *** 0.85≤α≤1.0,rolling is ellipsoidal particles'main form of motion,and the friction force changes according to a periodic sinusoidal *** the range of 0.80≤α<0.85,ellipsoidal particles primarily exhibit sliding as the dominant movement ***αdecreases within this range,the friction force progressively *** friction coefficientμcalculated through MD simulation is 0.128,which is consistent with the experimental data.

关键词： Molecular dynamics simulation Nanoparticle additives Ellipsoidal particles Tribological properties

Machine Learning Security Defense Algorithms Based on Metadata Correlation Features

在线全文

学校读者我要写书评

暂无评论

Computers, Materials & Continua 2024年第2期78卷 2391-2418页

作者： Ruchun jia jianwei Zhang Yi lin College of Computer Science Sichuan UniversityChengdu610065China

With the popularization of the Internet and the development of technology,cyber threats are increasing day by *** such as malware,hacking,and data breaches have had a serious impact on *** network security environment in the era of big data presents the characteristics of large amounts of data,high diversity,and high real-time *** security defense methods and tools have been unable to cope with the complex and changing network security *** paper proposes a machine-learning security defense algorithm based on metadata association *** control over unauthorized users through privacy,integrity,and *** user model is established and the mapping between the user model and the metadata of the data source is *** analyzing the user model and its corresponding mapping relationship,the query of the user model can be decomposed into the query of various heterogeneous data sources,and the integration of heterogeneous data sources based on the metadata association characteristics can be *** and classify customer information,automatically identify and perceive sensitive data,build a behavior audit and analysis platform,analyze user behavior trajectories,and complete the construction of a machine learning customer information security defense *** experimental results show that when the data volume is 5×103 bit,the data storage integrity of the proposed method is 92%.The data accuracy is 98%,and the success rate of data intrusion is only 2.6%.It can be concluded that the data storage method in this paper is safe,the data accuracy is always at a high level,and the data disaster recovery performance is *** method can effectively resist data intrusion and has high air traffic control *** can not only detect all viruses in user data storage,but also realize integrated virus processing,and further optimize the security defense effect of user big data.

关键词： Data-oriented architecture metadata correlation features machine learning security defense data source integration

Bibliometrics analysis based on the Web of Science:Current trends and perspective of gastric organoid during 2010-2023

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2024年第8期30卷 969-983页

作者： Kai-lin jiang Yue-Bo jia Xue-jiao Liu Qing-ling jia Li-Kun Guo Xiang-Xiang Wang Ke-Ming Yang Chen-Heng Wu Bei-Bei Liang jiang-Hong ling Department of Gastroenterology Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese MedicineShanghai 200021China Laboratory of Cancer Biology University of OxfordOxford OX37DQUnited Kingdom School of Traditional Chinese Medicine Shanghai University of Chinese MedicineShanghai 200021China Shanghai Key Laboratory of Molecular Imaging Shanghai University of Medicine and Health SciencesShanghai 201318China

BACKGROUND Three-dimensional organoid culture systems have been established as a robust tool for elucidating mechanisms and performing drug efficacy *** use of gastric organoid models holds significant promise for advancing personalized medicine ***,a comprehensive bibliometric review of this burgeoning field has not yet been *** To analyze and understand the development,impact,and direction of gastric organoid research using bibliometric methods using data from the Web of Science Core Collection(WoSCC)*** This analysis encompassed literature pertaining to gastric organoids published between 2010 and 2023,as indexed in the *** and VOSviewer were used to depict network maps illustrating collaborations among authors,institutions and keywords related to gastric ***,co-citation,and burst analysis methodologies were applied to assess the impact and progress of *** A total of 656 relevant studies were *** majority of research was published in gastroenterology-focused ***,Yana Zavros,Hans Clevers,James M Wells,Sina Bartfeld,and Chen Zheng were the 5 most productive authors,while Hans Clevers,Huch Meritxell,Johan H van Es,Marc Van de Wetering,and Sato Toshiro were the foremost influential scientists in this *** from the University Medical Center Utrecht,Netherlands Institute for Developmental Biology(Utrecht),and University of Cincinnati(Cincinnati,OH,United States)made the most significant ***,gastric organoids are used mainly in studies investigating gastric cancer(GC),Helicobacter pylori-infective gastritis,with a focus on the mechanisms of GC,and drug screening *** Key focus areas of research using gastric organoids include unraveling disease mechanisms and enhancing drug screening *** contributions from renowned academic institutions highlight this field’s dynamic growth.

关键词： Gastric organoid Gastric disease Bibliometrics analysis Gastric cancer Gastritis

Heat stress induced hepatocyte apoptosis in largemouth bass Micropterus salmoides via IRE1α/TRAF2/ASK1/JNK pathway

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Oceanology and Limnology 2024年第3期42卷 988-1000页

作者： Xuqian ZHAO Wenjia MAO Zijie lin Qufei ling School of Biology and Basic Medical Sciences Suzhou Medical College of Soochow UniversitySuzhou 215000China

Heat stress(HS)has been shown to adversely affect fish livers and can lead to extensive *** investigate the relationship between endoplasmic reticulum(ER)stress and HS-induced apoptosis in fish livers,we isolated and cultured primary hepatocytes of largemouth bass,Micropterus salmoides by trypsin method,then established an in-vitro model of liver cells under HS(35℃).The contents of lactic dehydrogenase(LDH)and hydrogen peroxide(H2O2)were determined to evaluate the effects of HS on hepatocyte injury and oxidative ***-qPCR was performed to discover the key genes in unfolded protein response(UPR)pathways involved at different HS *** inhibitor 4-PBA and IRE1αinhibitor 4μ8C were used to further investigate the effects of HS on IRE1αapoptosis pathway in *** show that HS led to significant increases in the release of LDH,the content of H2O2,and the expressions of oxidative protein folding genes(ero1αand pdi)under HS,suggesting severe hepatocyte injury and oxidative stress happened in heat-stressed largemouth bass *** continuous activation of IRE1αpathway genes(grp78,grp94,atf6,perk,eif2a,atf4,chop,ire1α,traf2,ask1,jnk1,and jnk2)indicated that HS led significantly to ER *** particular,the mRNA expression levels of ER stress-related genes(grp78,grp94,atf6,perk,ire1α,chop,jnk1,and jnk2)in the high temperature(HT)+4-PBA group and the HT+4μ8C group were significantly down-regulated under *** 4μ8C treatment,the expression levels of apoptosis-related genes(caspase-2,caspase-3,caspase-6,caspase-7,caspase-8,caspase-9,and caspase-10)and LDH content were significantly decreased,whereas the cell survival rate was significantly increased when given 4-PBA or 4μ8C *** findings demonstrate that HS could induce liver apoptosis of largemouth bass through the IRE1αpathway,which may act as a key switch mediating liver apoptosis of largemouth bass under HS.

关键词： heat stress Micropterus salmoides endoplasmic reticulum stress apoptosis oxidative stress

Success rate of current human-derived gastric cancer organoids establishment and influencing factors:A systematic review and meta-analysis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2024年第4期16卷 1626-1646页

作者： Kai-lin jiang Xiang-Xiang Wang Xue-jiao Liu Li-Kun Guo Yong-Qi Chen Qing-ling jia Ke-Ming Yang jiang-Hong ling Department of Gastroenterology Shuguang HospitalShanghai 200021China Department of Pathology Shuguang HospitalShanghai 200021China

BACKGROUND Human-derived gastric cancer organoids(GCOs)are widely used in gastric cancer research;however,the culture success rate is generally *** To explore the potential influencing factors,and the literature on successful culture rates of GCOs was reviewed using *** PubMed,Web of Science,and EMBASE were searched for *** trained researchers selected the studies and extracted *** 17.0 software was used for meta-analysis of the incidence of each outcome *** adjusted Methodological Index for Non-Randomized Studies scale was used to assess the quality of the included *** plots and Egger’s test were used to detect publication *** analyses were conducted for sex,tissue source,histo-logical classification,and the pathological tumor-node-metastasis(pTNM)cancer staging *** Eight studies with a pooled success rate of 66.6%were *** derived from women and men had success rates of 67%and 46.7%,*** from surgery or biopsy/endoscopic submucosal dissection showed success rates of 70.9%and 53.7%,*** of poorly-differentiated,moderately-differentiated and signet-ring cell cancer showed success rates of 64.6%,31%,and 32.7%,*** with pTNM stages I-II and III-IV showed success rates of 38.3%and 65.2%,respectively.Y-27632 and non-Y-27632 use showed success rates of 58.2%and 70%,*** generated with collagenase were more successful than those constructed with Liberase TH and TrypLE(72.1%vs 71%,respectively).EDTA digestion showed a 50%lower success rate than other methods(P=0.04).CONCLUSION GCO establishment rate is low and varies by sex,tissue source,histological type,and pTNM *** Y-27632,and using Liberase TH,TrypLE,or collagenase yields greater success than EDTA.

关键词： Gastric cancer organoids Human-derived organoids Gastric cancer Cell lines In vitro research models

Recent Advances in Mechanistic Understanding of Metal-Free Carbon Thermocatalysis and Electrocatalysis with Model Molecules

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2024年第7期16卷 74-97页

作者： Wei Guo linhui Yu ling Tang Yan Wan Yangming lin CAS Key Laboratory of Design and Assembly of Functional Nanostructures Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002People’s Republic of China Xiamen Key Laboratory of Rare Earth Photoelectric Functional Materials Xiamen Institute of Rare Earth MaterialsHaixi InstituteChinese Academy of SciencesXiamen 361021People’s Republic of China State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of MatterChinese Academy of SciencesFuzhou 350002People’s Republic of China Institute of Urban Environment Chinese Academy of SciencesXiamen 361021People’s Republic of China

Metal-free carbon,as the most representative heterogeneous metal-free catalysts,have received considerable interests in electro-and thermo-catalytic reac-tions due to their impressive performance and *** the past decade,well-designed carbon catalysts with tunable structures and heteroatom groups coupled with various characterization techniques have proposed numerous reaction ***,active sites,key intermediate species,precise structure-activity relationships and dynamic evolution processes of carbon catalysts are still rife with controversies due to the monotony and limitation of used experimental *** this Review,we sum-marize the extensive efforts on model catalysts since the 2000s,particularly in the past decade,to overcome the influences of material and structure limitations in metal-free carbon *** both nanomolecule model and bulk model,the real contribution of each alien species,defect and edge configuration to a series of fundamentally important reactions,such as thermocatalytic reactions,electrocatalytic reactions,were systematically *** with in situ techniques,isotope labeling and size control,the detailed reaction mechanisms,the precise 2D structure-activity relationships and the rate-determining steps were revealed at a molecular ***,the outlook of model carbon catalysis has also been proposed in this work.

关键词： Metal-free carbon catalysts Model catalyst Electrocatalysis Active site Reaction mechanisms

Factors influencing willingness to participate in ophthalmic clinical trials and strategies for effective recruitment

在线全文

学校读者我要写书评

暂无评论

International Journal of Ophthalmology(English edition) 2024年第1期17卷 157-163页

作者： jia-En Liang Meng-Yin Liang En-En Zhang Yu-Ying Peng ling-ling Chen jia-Yu Deng Ting lin Jun Fu jia-Ni Zhang Shao-Li Li Fei Li Hui-Ming Xaio Wen-Min Huang Yu-Hong Liu State Key Laboratory of Ophthalmology Zhongshan Ophthalmic CenterSun Yat-sen UniversityGuangdong Provincial Key Laboratory of Ophthalmology and Visual ScienceGuangdong Provincial Clinical Research Center for Ocular DiseasesGuangzhou 510060Guangdong ProvinceChina

AIM:To explore the factors influencing individuals’willingness to participate in ophthalmic clinical ***:A questionnaire survey was conducted from January to April 2021 among patients and their family members at Zhongshan Ophthalmic Center,Sun Yat-sen University,in Guangzhou,*** survey gathered data on respondents’willingness,demographic and socioeconomic profiles,as well as their reasons and concerns regarding engagement in clinical ***:Of the 1078 residents surveyed(mean age 31.2±13.1y;65.8%females)in Guangzhou,749(69.5%)expressed a willingness to participate in future ophthalmic clinical *** characteristics associated with greater willingness included a younger age,lower annual income,higher education,prior participation experience,previous ophthalmic treatment,and a better understanding of clinical *** the exception of age,these characteristics were significantly linked to a higher *** primary barrier to participation,expressed by 64.8%of those willing and 54.4%of those unwilling,was“Uncertain efficacy”.In terms of motivations,the willing group ranked“Better therapeutic benefits”(35.0%),“Professional monitoring”(34.3%),and“Trust in healthcare professionals”(33.1%)as their top three reasons,whereas the unwilling participants indicated“Full comprehension of the protocol”(46.2%)as the key ***:This study reveals a substantial willingness to participate in ophthalmic clinical trials and demonstrates the predictive role of demographic and socioeconomic *** in motivators and concerns between willing and unwilling participants highlight the significance of tailored recruitment ***,the need for and trust in healthcare professionals stand out as powerful motivations,underscoring the importance of enhancing physician-patient relationships,adopting patient-centered communication approaches,and addressing individualized needs to improve accrual rates.

关键词： participation willingness recruitment strategy ophthalmic clinical trial

Experimental,Numerical,and Analytical Studies on the Bending of Mechanically lined Pipe

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

China Ocean Engineering 2024年第2期38卷 221-232页

作者： WEI Wen-bin YUAN lin ZHOU jia-sheng LIU Zheng State Key Laboratory of Hydraulic Engineering Simulation and Safety Tianjin UniversityTianjin 300072China School of Civil Engineering Tianjin UniversityTianjin 300072China School of Mechanical Engineering Tianjin UniversityTianjin 300072China

Mechanically lined pipe(MLP)is often used for offshore oil and gas transport because of its low cost and corrosion *** installation and operation,the pipe may undergo severe bending deformation,which causes the liner to separate from the outer pipe and buckles,affecting the stability of the whole *** this paper,the buckling response of MLP subjected to bending is investigated to clarify its bending characteristics by employing both experiments,numerical simulation,as theoretical *** types of MLPs were manufactured with GB 45 carbon steel(SLP)and Al 6061(ALP)used as the outer pipe material,*** hydraulic expansion and bending experiments of small-scale MLPs are *** addition to the ovalized shape of the cross-section for the SLP specimens,the copper liner was found to wrinkle on the compressive *** contrast,the liner of ALP remains intact without developing any wrinkling and collapse *** addition,a dedicated numerical framework and theoretical models were also *** was found both the manufacturing and bending responses of the MLP can be well reproduced,and the predicted maximum moment and critical curvatures are in good agreement with the experimental results.

关键词： lined pipe bending nonlinear ring theory buckling plasticity