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The Psychosomatic Traits of“People with the Five Elements in Traditional Chinese Medicine”:A Qualitative Study

Biomedical and Environmental Sciences 2023年第11期36卷 1068-1078页

作者： LI jia jia YANG Xin Yu ZHANG hong Jun YIN Dong Qing ZHANG Jin Tao CUI Jing Wen HAN Jing Dong MA Yan jia hong xiao The National Clinical Research Center for Mental Disorders&Beijing Key Laboratory of Mental Disorders Beijing Anding HospitalCapital Medical UniversityBeijing 100088China Advanced Innovation Center for Human Brain Protection Capital Medical UniversityBeijing 100088China School of Life Sciences Peking UniversityBeijing 100871China The First Hospital Affiliated to Beijing University of Chinese Medicine DongZhimen HospitalBeijing 100700China State Key Laboratory of Cognitive Neuroscience and Learning and IDG/McGovern Institute for Brain Research Beijing Normal UniversityBeijing 100875China Peking-Tsinghua Center for Life Sciences Academy for Advanced Interdisciplinary StudiesPeking UniversityBeijing 100871China Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing 100700China

Objective To identify the representative attributes of the five elements of a person with a qualitative methodology and provide the basis for the clinical diagnosis and treatment of“people with the five elements in traditional Chinese medicine(TCM).”Methods Data collected from the literature review,two sessions of brainstorming of experts with related experience in“people with the five elements in TCM”from October 2020 to December 2020,and six rounds of in-depth interviews with 30 participants who had various attributes of the five elements from March 2021 to October 2021 were *** was used in this study,and theming and synthesizing were used to analyze the *** A total of 31 experts and 30 interviewees participated in this *** median age of the experts and interviewees were 48.0 and 38.5 years,respectively;51.66%and 54.8%of experts and interviewees,respectively,were *** descriptors of facial diagrams of“people with the five elements in TCM”were complexion,shape,distribution state of facial bones,convergence trend of facial muscles,and facial expression.A theoretical model of“people with the five elements in TCM”was shaped based on these *** The study suggests a possibility for bridging the gap between personality and bodily state,identifying an avenue for personality research from the perspective of TCM.

关键词： People with the five elements in TCM Brainstorming In-depth interviews Triangulation Personality Traditional Chinesemedicine

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Influence of Inactivation Treatment of Ship′s Ballast Water on Corrosion Resistance of Ship Steel Plate

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Journal of Iron and Steel Research International 2013年第11期20卷 85-89页

作者： WANG Zi-xi ZHAO Jing-hui jia xiao-hong FANG jian-guo ZHANG Bo DING Guo-qing Department of Precision Instruments and Mechanology State Key Laboratory of TribologyTsinghua University Powder Metallurgy Division Advanced Technology and Materials Co. COSCO Shipbuilding Industry Co. Qingdao Marine Corrosion Institute China Iron and Steel Research Institute Group

The effect of seawater after ultraviolet inactivation on corrosion of a shipbuilding steel plate was investiga- ted by means of natural corrosion potential experiments and immersion corrosion test. The effects of natural seawater and treated seawater after ultraviolet inactivation on corrosion of the selected steel plate samples were compared with each other. The results showed that there was no obvious change in the chemical composition of treated seawater compared with natural seawater. The corrosion potential slightly increased by 10 mV, whereas the corrosion rate rose significantly by 20~. The experiments verified the naturally formed biofilm in the natural seawater for the inhi- bition of corrosion on the shipbuilding steel plate. The possible influences of ballast water treatment on biofilm by ul- traviolet and electrolysis inactivation under the condition of practical usage were also investigated. And it was found that ballast water treatment methods with no continuous disinfection could protect original tank biofilm structure, reducing the intensity of tank corrosion.

关键词： corrosion ballast water biofilm

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High-dense nanocrystalline W-based alloy prepared by hot isostatic pressing with uniform microstructure, ultrahigh hardness and good thermal stability

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Tungsten 2025年第1期7卷 120-136页

作者： Zao-Ming Wu Lin He Lin-Sen Ye xiao-Feng Yang jia-jia Zhang hong-Bo Lei Institute of Materials China Academy of Engineering Physics

High-density uniform microstructure nanocrystalline W-10wt.% Cr-5wt.% Y（W-10Cr-5Y） alloy with an average grain size of 85 nm and a relative density of 99.8% was successfully prepared.W-Cr-Y alloys with different amounts of second-phase particles were prepared by high-energy ball milling and hot isostatic pressing *** effects of composition design,ball milling parameters,and sintering parameters on the microstructure of W-Cr-Y alloys were studied.A feasible technology for controlling the synthesis of high-density nanocrystalline W-based alloys has been *** microstructure analysis of nanocrystalline W-10Cr-5Y alloy shows that there are two types of doping in the second phase:intergranular doping and intragranular *** "uniform distribution YOx-rich particles" effectively suppresses the grain growth of W and leads to the formation of nanocrystalline W-10Cr-5Y alloy.W-10Cr-5Y has an ultra-high hardness,with a Vickers hardness of 1312±12 kgf·***-temperature annealing treatment shows that W-10Cr-5Y has good thermal stability at 1000 and1100℃,as demonstrated by the comparison of Vickers hardness and grain size between annealed and unannealed alloys.

关键词： Hot isostatic pressing Microstructure Nanocrystalline tungsten Thermal stability Vickers hardness

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抑郁症的中西医结合实验研究

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中国中西医结合杂志 2009年第3期29卷 200-201页

作者：贾竑晓首都医科大学附属北京安定医院北京100088

目前抑郁症的中西医结合实验研究大多集中在单味中药和复方的抗抑郁机理方面,另外一些研究还探讨了电针治疗抑郁症的有效机制.

关键词：抑郁症单味中药忧郁症情感性精神病抑郁动物模型实验研究中西医结合

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Synthesis and Characterization of Sulfonated Polyphosphazene-graft-Polystyrene Copolymers for Proton Exchange Membranes

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Chinese Journal of Polymer Science 2014年第2期32卷 151-162页

作者： Min-lan He Hu-lin Xu Yan Dong jia-hong xiao Peng Liu Feng-yan Fu Saghir Hussain Shu-zhen Zhang Chao-jun Jing Qun Yu 朱长进 Department of Applied Chemistry Beijing Institute of Technology Beijing Qintian Science & Technology Development Co. Ltd Beijing Institute of Transfusion Medicine

A novel series of polyphosphazene-grafl-polystyrene （PP-g-PS） copolymers were successfully prepared by atom transfer radical polymerization （ATRP） of styrene monomers and brominated poly（bis（4-methylphenoxy）phosphazene） macroinitiator. The graft density and the graft length could be regulated by changing the bromination degree of the macroinitiator and the ATRP reaction time, respectively. The PP-g-PS copolymers readily underwent a regioselective sulfonation reaction, which occurred preferentially at the polystyrene sites, producing the sulfonated PP-g-PS copolymers with a range of ion exchange capacities. The resulting sulfonated PP-g-PS membranes prepared by solution casting showed high water uptake, low water swelling and considerable proton conductivity. They also exhibited good oxidative stability and high resistance to methanol crossover. Morphological studies of the membranes by transmission electron microscopy showed clear nanophase-separated structures resulted from hydrophobic polyphosphazene backbone and hydrophilic polystyrene sulfonic acid segments, indicating the formation of proton transferring tunnels. Therefore, these sulfonated copolymers may be candidate materials for proton exchange membranes in direct methanol fuel cell （DMFC） applications.

关键词： Atom transfer radical polymerization Direct methanol fuel cell Graft copolymers Proton exchange membrane Polyphosphazenes.

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地铁列车在车辆段侧向过岔的安全性分析

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铁道工程学报 2018年第2期35卷 79-83页

作者：贾晓宏中铁第一勘察设计院集团有限公司西安710043

研究目的:道岔是轨道线路的薄弱环节,是影响列车安全平稳通过的关键因素。道岔最主要的特征就是其横截面外形随长度方向的变化而变化,使得线路存在较大的横向不平顺和垂向不平顺。本文通过多体动力学软件UM建立地铁A型车-道岔耦合动力... 详细信息

研究目的:道岔是轨道线路的薄弱环节,是影响列车安全平稳通过的关键因素。道岔最主要的特征就是其横截面外形随长度方向的变化而变化,使得线路存在较大的横向不平顺和垂向不平顺。本文通过多体动力学软件UM建立地铁A型车-道岔耦合动力学模型,以7号右开道岔为例,建立地铁A型车辆模型和道岔变截面轨道模型,对侧向通过道岔动力学性能进行分析,并运用我国现行车辆运行安全性评定标准进行分析评估。研究结论:(1)当地铁A型车辆以50 km/h及以下速度侧向通过7号道岔时,所有行车安全性指标均满足相应的安全标准,可以保证列车运行安全,但轮对横向位移较大,车辆有横向晃车的趋势;(2)车辆速度越大,轮轨横向力最大值也越大;(3)该研究成果可用于铁路、地铁车辆段列车过岔安全性评估,具有一定的工程实用意义。

关键词：地铁列车道岔车辆段安全性分析评估

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Tumor inflammation-specific self-amplifying fluorescent molecular probes induce an anti-tumor immune response

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Science China Chemistry 2025年第1期68卷 273-287页

作者： Shuguang Yang Lijun Hu hong xiao Zecong xiao Xintao Shuai PCFM Lab of Ministry of Education School of Materials Science and Engineering Sun Yat-sen University Department of Ultrasound The Fifth Affiliated Hospital Sun Yat-sen University Department of Medical Ultrasound The Third Affiliated Hospital of Sun Yat-sen University Nanomedicine Research Center The Third Affiliated Hospital of Sun Yat-sen University

Enhancing the concentration of exogenous molecular drugs within the tumor microenvironment through enzyme-catalyzed polymerization presents a novel strategy for cancer therapy. Nonetheless, the optimization of the catalytic efficiency is often impeded by the inefficient expression of enzymes. Herein, we reported a self-amplifying fluorescent molecular probe, Bis-HTPICG, for photodynamic therapy(PDT) and subsequent PDT-induced immunoreaction. The Bis-HTP-ICG probe possesses a noticeable enzyme-catalyzed polymerization facilitated by myeloperoxidase(MPO), a crucial enzyme secreted by neutrophils at inflammation sites. Upon exposure to laser irradiation, Bis-HTP-ICG showed a high PDT efficacy, inducing an acute inflammatory response that stimulates further recruitment of neutrophils and then elevated MPO secretion. The heightened level of MPO enhances the accumulation of the Bis-HTP-ICG via self-polymerization or binding with intratumoral proteins following MPO enzyme catalysis, instigating a self-amplifying chain reaction cycle involving Bis-HTP-ICG, neutrophils and ***, PDT efficiently incites immunogenic cell death(ICD) in tumor cells, initiating an anti-tumor immune response including dendritic cells(DCs) maturation, T cell proliferation and reprogramming of tumor-associated neutrophils(TANs). This work portrays a promising strategy for self-amplification of fluorescent molecular probes through adjustable enzyme levels,potentially offering a unique avenue to enhance the tumor accumulation of molecular drugs for improved tumor therapy.

关键词： fluorescent molecular probes self-amplifying myeloperoxidase photodynamic therapy

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抗精神病药物所致闭经的中医药治疗

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中国中西医结合杂志 2010年第11期30卷 1125-1127页

作者：贾竑晓王娣首都医科大学附属北京安定医院

闭经是抗精神病药物长期应用常见的不良反应。国外研究显示[1]：精神障碍患者服用抗精神病药后继发性闭经高达17%-78%。抗精神病药物所致闭经的机制为抗精神病药物对下丘脑D2受体有拮抗作用,抑制催乳素抑制因子,使催乳素（PRL）升高。... 详细信息

闭经是抗精神病药物长期应用常见的不良反应。国外研究显示[1]：精神障碍患者服用抗精神病药后继发性闭经高达17%-78%。抗精神病药物所致闭经的机制为抗精神病药物对下丘脑D2受体有拮抗作用,抑制催乳素抑制因子,使催乳素（PRL）升高。持续的高PRL抑制下丘脑的促性腺素释放激素分泌，从而使促性腺素低下，卵巢功能低下而闭经。

关键词：抗精神病药物继发性闭经药物所中医药治疗精神障碍患者卵巢功能低下促性腺素不良反应

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腾格里沙漠东南缘不同生境白刺(Nitraria)灌丛沙堆的空间分布格局

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环境科学 2008年第7期29卷 2046-2053页

作者：贾晓红李新荣中国科学院寒区旱区环境与工程研究所沙坡头沙漠试验研究国家站兰州730000

运用地统计学和数量生态学方法,从维持天然白刺灌丛稳定性和持久生态效益角度出发,对腾格里沙漠东南缘不同生境白刺灌丛沙堆的空间异质性进行了研究,分析了不同生境白刺固沙生态效益.结果表明,生境地下水埋深和白刺植株发育状况的差异... 详细信息

运用地统计学和数量生态学方法,从维持天然白刺灌丛稳定性和持久生态效益角度出发,对腾格里沙漠东南缘不同生境白刺灌丛沙堆的空间异质性进行了研究,分析了不同生境白刺固沙生态效益.结果表明,生境地下水埋深和白刺植株发育状况的差异直接影响了白刺耐沙埋的能力,间接地影响了白刺沙堆的固沙效应.湖盆低地白刺种群的植株盖度、密度和生物量显著高于山前冲积扇区（p〈0.01）,植株高度则相反,且无显著差异（p〉0.05）.湖盆低地的半固定生境沙堆高度平均为1.20m,单个沙堆积沙体积平均为88.19 m^3,固定生境的山前冲积扇沙堆高度平均为1.14 m,单个沙堆积沙体积平均为33.16 m^3.不同生境条件下,白刺沙堆的斑块大小和分布存在明显差异（p〈0.01）.湖盆低地的白刺灌丛沙堆趋向于大斑块、小密度,空间自相关距离较长,而山前冲积扇区相反.湖盆低地由自相关因素引起的沙堆大小和积沙体积空间异质性占主要部分,分别体现在1.2-84 m和1.2-505 m尺度;而山前冲积扇的随机因素引起的沙堆大小和积沙体积空间异质性占到100%,在100 m以下尺度该区白刺灌丛沙堆大小和积沙体积具有恒定的变异,其空间分布格局在这个尺度无规律体现呈随机分布.

关键词：白刺沙堆空间分布固沙效应

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2017年青岛冬季一次云凝结核观测的研究分析

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中国海洋大学学报（自然科学版） 2018年第8期48卷 10-19页

作者：綦佳佳姚小红中国海洋大学海洋环境与生态教育部重点实验室山东青岛266100

2017年1月2—25日在青岛崂山区观测了云凝结核浓度(NCCN)及气溶胶数谱,分析了青岛冬季平均及不同天气下云凝结核浓度及活化率(AR)的特征。观测结果表明:在0.05%~0.6%过饱和度(SS)之间,NCCN变化范围为(1.1~6.4)×103 cm-3;AR变化范围为0.... 详细信息

2017年1月2—25日在青岛崂山区观测了云凝结核浓度(NCCN)及气溶胶数谱,分析了青岛冬季平均及不同天气下云凝结核浓度及活化率(AR)的特征。观测结果表明:在0.05%~0.6%过饱和度(SS)之间,NCCN变化范围为(1.1~6.4)×103 cm-3;AR变化范围为0.06~0.35。受局地汽车尾气排放的影响,凝结核浓度(NCN)和0.2%~0.6%SS下NCCN的日变化呈双峰型;AR日变化呈双谷型。不同天气之间NCCN及AR差别明显;0.2%SS下,NCCN从高到低的排序依次为雾霾、雾、霾、晴、雨、雪;AR的排序依次为雪、雾、雾霾、霾、雨、晴。而雾霾、霾天的活化率较高,这主要是因为气溶胶中含有相对较高比例的积聚模态颗粒物(大于100nm)。青岛观测期间平均及不同天气下的CCN活化谱均为典型大陆型。

关键词：云凝结核活化率粒径分布日变化

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