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A homopolymolybdate-supported plate-like 2D cobalt network constructed from a new pyrazole-amide-pyridyl ligand: highly electrochemical activity in both capacitive performance and the detection of Cr(Ⅵ)

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Tungsten 2024年第2期6卷 422-427页

作者： Xiu-Li Wang Yong-Zhen Chen zhi-Han Chang Yu-Chun Lin Jing-Yi Ma College of Chemistry and Materials Engineering Bohai UniversityJinzhou 121013China Professional Technology Innovation Center of liaoning Province for Conversion Materials of Solar Cell Jinzhou 121013China

By employing a new semi-rigid pyrazole-amide-derived bis(pyridyl)ligand[N,N'-bis(4-picolylamine)-1-hydropyrazole(4-dpap)],a new homopolymolybdate-based two-dimensional(2D)plate-like complex[Co(4-dpap)(H_(2)O)(β-Mo_(8)O_(2)6)1/2](1)has been prepared under solvothermal condition and structurally ***β-Mo_(8)anions are fi xed between the 2D metal–organic networks[Co(4-dpap)(H_(2)O)]n 2n+via hydrogen-bonding *** 1 possesses satisfactory specifi c capacitance of 1512.4 F·g^(−1)(current density:1 A·g^(−1))and good cycling stability(90.8%after 1000 cycles).Moreover,1 represents a promising amperometric sensor for measurement of Cr(Ⅵ)with low detection limit(0.042μmol·L^(−1))and high *** insertion ofβ-Mo_(8)anions between the unique 2D metal−organic networks improves the active area of polyoxometalates,which further promotes electrochemical performance.

关键词： Homopolymolybdate Metal–organic network Pyrazole-amide-derived bis(pyridyl)ligand Supercapacitor Electrochemical sensor

Luteolin alleviates sorafenib-induced ferroptosis of BRL-3A cells through modulation of the Nrf2/GPX4 signaling pathway

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Traditional Medicine Research 2024年第10期9卷 1-9页

作者： Bo-Wen Zhang Di Yang Jin-Tao Li Mei-Hao Peng jia-Qing liao Qi Zhao Yi-Xi Yang Qiu-Xia Lu Engineering Research Center of Sichuan-Tibet Traditional Medicinal Plant Chengdu UniversityChengdu 610106China School of Food and Biological Engineering Chengdu UniversityChengdu 610106China School of Pharmacy Chengdu UniversityChengdu 610106China

Background:Luteolin is a flavonoid chemical that exists in a variety of medicinal and edible plants and holds many biologically active properties in liver protection,anti-cancer,antioxidants,anti-inflammatory,neuroprotective,*** to its hepatoprotective properties,luteolin was selected to co-treat with sorafenib,one of the approved protein kinase inhibitors,to reduce sorafenib-induced normal liver cell ***:The BRL-3A cell line was treated with sorafenib to establish a liver injury model,followed by luteolin *** cell viability was detected,and the mechanism of action was detected by immunofluorescence,western blotting,and real-time quantitative ***:The research findings demonstrated that luteolin could increase cystine/glutamate transporter xCT(SLC7A11)and glutathione peroxidase 4(GPX4)expression and display a chelating effect on iron,which led to increased glutathione and decreased malondialdehyde,Fe^(2+) and lipid reactive oxygen species contents in BRL-3A cells,and the sorafenib-induced mitochondrial membrane potential decrease was also *** addition,when sorafenib caused the accumulation of lipid reactive oxygen species,luteolin could help release this oxidative stress by activating nuclear factor E2-related factor 2(Nrf2)and up-regulating the expression of the associated genes heme oxygenase 1(HO-1)and quinone oxidoreductase 1(NQO1).Conclusion:Therefore,luteolin may ameliorate sorafenib-induced ferroptosis by activating the Nrf2-associated pathway without any impact on sorafenib anti-cancer *** can be used as an adjuvant to sorafenib to reduce liver injury in patients with hepatocellular carcinoma.

关键词： luteolin sorafenib liver injury ferroptosis Nrf2/GPX4

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浅谈微扰动技术在地铁改造项目中的应用

建筑科技 2024年第5期8卷 147-150页

作者：贾智城盾隧安地下工程有限公司上海201108

根据中国城市轨道交通协会统计,截至2023年上半年,中国内地累计有57个城市投运城市轨道交通运营线路10 566 km,新增城市轨道交通运营线路长度236 km,预计下半年将开通运营线路600 km。随着运营线路的不断增长,部分既有地铁设施已经无法... 详细信息

根据中国城市轨道交通协会统计,截至2023年上半年,中国内地累计有57个城市投运城市轨道交通运营线路10 566 km,新增城市轨道交通运营线路长度236 km,预计下半年将开通运营线路600 km。随着运营线路的不断增长,部分既有地铁设施已经无法满足现行运营需求,或者与周边商业建筑规划不相协调,就需要通过地铁设施改造来提高地铁的运营效率和服务水平,为市民提供更加便捷和舒适的出行体验。由于地铁线路周边建构筑物繁多,再加上错综的地上地下管线,周边环境敏感复杂。为了减少对周边环境的扰动,且不影响地铁正常运营,结合上海轨道交通1号线莲花路站南站台改造工程中锚杆静压钢管桩施工技术,和上海轨道交通2号线静安寺站3号口改造项目中MJS施工技术和人工挖孔钢管桩施工技术,浅谈微扰动施工技术在地铁改造项目中的应用。

关键词：地铁改造项目微扰动施工技术锚杆静压钢管桩 MJS施工技术人工挖孔钢管桩

AICAR-based exercise mimetic alleviates aging-induced memory impairment through activating AMPK and improving mitochondrial quality control

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Food Science and Human Wellness 2024年

作者： Bo liao Yuan-Yuan Qin Shan-Yao Pan Gui-Ping Wang zhi jiang Bin Li Yao Wang Yu-Long Wang Ming-Chao Zhou Yong Zhang Gang Liu Zheng-Hong Qin Xue-Feng Xi Li Luo Department of Pharmacology and Laboratory of Aging and Nervous Diseases (SZS0703) jiangsu Key Laboratory of Translational Research and Therapy for NeuroPsycho-Diseases， Soochow University School of Pharmaceutical Science College of Physical Education， Henan University School of Physical Education and Sports Science， Soochow University Department of Pharmacy， Suzhou Hospital of Traditional Chinese Medicine Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine Laboratory Animal Center， Medical College of Soochow University Center Lab of Ninth People's Hospital of Suzhou Department of Rehabilitation Medicine， Nan‘ao People's Hospital of Dapeng New District Rehabilitation Department， The First Affiliated Hospital of Shenzhen University， Shenzhen Second People's Hospital Tianjin Key Lab of Exercise Physiology and Sports Medicine， Tianjin University of Sport Department of Rehabilitation Medicine， Nanfang Hospital， Southern Medical University

Growing evidence suggests that exercise can provide neuroprotection by improving mitochondrial quality control (MQC) on the aged brain. Adenosine 5'-monophosphate (AMP)-activated protein kinase (AMPK) signaling responsiveness declines with aging. However， whether AMPK plays a role in the exercise-mediated improvement of memory and MQC in the aged hippocampus remains to be established. AICAR (5-Aminoimidazole 4-carboxamide ribonucleoside)， a pharmacological agonist of AMPK， has been proposed to be an exercise mimetic recently. However， it has not been clarified whether AICAR could mimic the effects of exercise on the aged hippocampus through improvement of MQC. In this study， AICAR (AMPK agonist) and Compound C (AMPK inhibitor) were used to investigate if AMPK plays a key role in exercise-induced improvement of MQC and if AICAR could act as an exercise mimetic through improvement of MQC in aged hippocampus. Both exercise and AICAR improved the memory of aged mice and increased AMPK phosphorylation in the aged hippocampus. Exercise， but not AICAR， improved mitochondrial respiratory function in the aged hippocampus and increased the Microtubule associated protein 1 light chain 3 (LC3) II/LC3 I ratio and the protein expression of LC3 II and Autophagy Related Protein 7 (ATG7) in the lysate of whole hippocampal tissue. Both exercise and AICAR increased the ratio of LC3 II/LC3 I and the protein expression of LC3 II in the mitochondrial fractions of the hippocampus. Regarding mitochondrial dynamics， neither exercise training nor AICAR changed the protein level of Mitofusin2 (Mfn2). Exercise， but not AICAR， increased the protein level of Dynamin-related protein 1 (Drp1). Furthermore， both exercise training and AICAR increased the protein level of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α)， a modulator of mitochondrial biogenesis. Compound C abolished the exercise-induced effects on memory in aged mice (Fig. 1)， AMPK phosphorylation， autophagy， mitop

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石化建筑抗爆新标准在设计中的应用分析

化肥设计 2024年第5期62卷 56-61页

作者：廖志绘中国五环工程有限公司湖北武汉430223

新修订的GB/T 59779—2022《石油化工建筑物抗爆设计标准》变化较大,新增内容较多。根据多年工作经验,从建筑专业角度出发,结合设计实例,解读评估报告,并对新建抗爆建筑在设计中需要注意的问题进行梳理和总结,为同业提供一定参考和借鉴。

关键词：石油化工建筑物抗爆设计标准新建化工建筑抗爆设计安全性评估报告解读

Optical study of magnetic topological insulator MnBi_(4)Te_7

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Chinese Physics B 2024年第1期33卷 231-235页

作者：廖知裕沈冰邱祥冈许兵 Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory of Optoelectronic Materials and Technologies School of PhysicsSun Yat-Sen UniversityGuangzhou 510275China Songshan Lake Materials Laboratory Dongguan 523808China

We present an infrared spectroscopy study of the magnetic topological insulator MnBi_(4)Te_7 with antiferromagnetic(AFM) order below the Neel temperature TN= 13 K. Our investigation reveals that the low-frequency optical conductivity consists of two Drude peaks, indicating a response of free carriers involving multiple bands. Interestingly, the narrow Drude peak grows strongly as the temperature decreases, while the broad Drude peak remains relatively unchanged. The onset of interband transitions starts around 2000 cm^(-1), followed by two prominent absorption peaks around 10000 cm^(-1) and 20000 cm^(-1). Upon cooling, there is a notable transfer of spectral weight from the interband transitions to the Drude response. Below TN, the AFM transition gives rise to small anomalies of the charge response due to a band *** findings provide valuable insights into the interplay between magnetism and the electronic properties in MnBi_(4)Te_7.

关键词： infrared spectroscopy magnetic topological insulator Drude model band reconstruction

穿支皮瓣中Choke vessels的相关研究与展望

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中国矫形外科杂志 2024年第14期32卷 1309-1313页

作者：霍磊谭琪高加智谢佳宁山东第二医科大学临床医学院山东潍坊261053 潍坊市人民医院创伤骨科山东潍坊261000

Choke vessels作为连接穿支皮瓣中相邻血管体的桥梁,在提高穿支皮瓣存活率方面发挥重要作用。目前,如何提高穿支皮瓣存活率的研究重点是通过施加不同措施增加Choke vessels的供血而改善皮瓣血运。本文通过对Choke vessels在穿支皮瓣中... 详细信息

Choke vessels作为连接穿支皮瓣中相邻血管体的桥梁,在提高穿支皮瓣存活率方面发挥重要作用。目前,如何提高穿支皮瓣存活率的研究重点是通过施加不同措施增加Choke vessels的供血而改善皮瓣血运。本文通过对Choke vessels在穿支皮瓣中的研究进展进行回顾,分析不同干预措施对Choke vessels的影响,旨在为未来提高穿支皮瓣存活率的相关研究提供参考方向。

关键词：穿支皮瓣 Choke vessels 血管内皮生长因子(VEGF)

Two haplotype-resolved genome assemblies for AAB allotriploid bananas provide insights into banana subgenome asymmetric evolution and Fusarium wilt control

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Plant Communications 2024年第2期5卷 243-260页

作者： Wen-Zhao Xie Yu-Yu Zheng Weidi He Fangcheng Bi Yaoyao Li Tongxin Dou Run Zhou Yi-Xiong Guo Guiming Deng Wenhui Zhang Min-Hui Yuan Pablo Sanz-Jimenez Xi-Tong Zhu Xin-Dong Xu Zu-Wen Zhou zhi-Wei Zhou jia-Wu Feng Siwen Liu Chunyu Li Qiaosong Yang Chunhua Hu Huijun Gao Tao Dong jiangbo Dang Qigao Guo Wenguo Cai jianwei Zhang Ganjun Yi jia-Ming Song Ou Sheng Ling-Ling Chen Institute of Fruit Tree Research Guangdong Academy of Agricultural SciencesKey Laboratory of South Subtropical Fruit Biology and Genetic Resource UtilizationMinistry of Agriculture and Rural AffairsGuangdong Provincial Key Laboratory of Tropical and Subtropical Fruit Tree ResearchGuangzhou 510640China College of Informatics Huazhong Agricultural UniversityWuhan 430070China State Key Laboratory for Conservation and Utilization of Subtropical Agro-bioresources College of Life Science and TechnologyGuangxi UniversityNanning 530004China College of Horticulture and Landscape Architecture Southwest UniversityChongqing 400715China

Bananas(Musa spp.)are one of the world’s most important fruit crops and play a vital role in food security for many developing *** banana cultivars are triploids derived from inter-and intraspecific hybrid-izations between the wild diploid ancestor species Musa acuminate(AA)and ***(BB).We report two haplotype-resolved genome assemblies of the representative AAB-cultivated types,Plantain and Silk,and precisely characterize ancestral contributions by examining ancestry mosaics across the *** asymmetric evolution is observed in their subgenomes,which can be linked to frequent homol-ogous exchange *** reveal the genetic makeup of triploid banana cultivars and verify that subge-nome B is a rich source of disease resistance *** 58.5%and 59.4%of Plantain and Silk genes,respectively,are present in all three haplotypes,with>50%of genes being differentially expressed alleles in different *** observed that the number of upregulated genes in Plantain is significantly higher than that in Silk at one-week post-inoculation with Fusarium wilt tropical race 4(Foc TR4),which con-firms that Plantain can initiate defense responses faster than ***,we compared genomic and transcriptomic differences among the genes related to carotenoid synthesis and starch metabolism between Plantain and *** study provides resources for better understanding the genomic architecture of culti-vated bananas and has important implications for Musa genetics and breeding.

关键词： bananas Plantain Silk asymmetric evolution homologous exchange Fusarium wilt

Towards High-Performance Graph Processing: From a Hardware/Software Co-Design Perspective

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Journal of Computer Science & Technology 2024年第2期39卷 245-266页

作者：廖小飞赵文举金海姚鹏程黄禹王庆刚赵进郑龙张宇邵志远 National Engineering Research Center for Big Data Technology and System School of Computer Science and Technology Huazhong University of Science and TechnologyWuhan 430074China Services Computing Technology and System Laboratory School of Computer Science and Technology Huazhong University of Science and TechnologyWuhan 430074China Cluster and Grid Computing Laboratory School of Computer Science and TechnologyHuazhong University of Science and TechnologyWuhan 430074China Zhejiang Lab Hangzhou 311121China

Graph processing has been widely used in many scenarios,from scientific computing to artificial *** processing exhibits irregular computational parallelism and random memory accesses,unlike traditional ***,running graph processing workloads on conventional architectures(e.g.,CPUs and GPUs)often shows a significantly low compute-memory ratio with few performance benefits,which can be,in many cases,even slower than a specialized single-thread graph *** domain-specific hardware designs are essential for graph processing,it is still challenging to transform the hardware capability to performance boost without coupled software *** article presents a graph processing ecosystem from hardware to *** start by introducing a series of hardware accelerators as the foundation of this ***,the codesigned parallel graph systems and their distributed techniques are presented to support graph ***,we introduce our efforts on novel graph applications and hardware *** results show that various graph applications can be efficiently accelerated in this graph processing ecosystem.

关键词： graph processing hardware accelerator software system high performance ecosystem