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Impact of being overweight on the surgical outcomes of patients with gastric cancer: A meta-analysis

World Journal of Gastroenterology 2013年第28期19卷 4596-4606页

作者： Xiang-Song Wu Wen-Guang Wu Mao-Lan Li jia-Hua Yang Qi-Chen Ding Lin Zhang jia-sheng mu Jun Gu Ping Dong jian-Hua Lu Ying-Bin Liu Department of General Surgery Xinhua Hospital Shanghai Jiao Tong University School of Medicine

AIM: To investigate the effect of being overweight on the surgical results of patients with gastric cancer. METHODS: Comprehensive electronic searches of the PubMed, Web of Science, and Cochrane Library databases were conducted. Studies were identified that included patients with surgical complications from gastric cancer who were classified as normal weight [body mass index (BMI) < 25 kg/m 2 ] or overweight (BMI ≥ 25 kg/m 2 ). The operative time, retrieved lymph nodes, blood loss, and long-term survival were analyzed. A subgroup analysis was conducted based on whether patients received laparoscopic or open gastrectomy procedures. All statistical tests were performed using ReviewerManager 5.1.2 software. RESULTS: This meta-analysis included 23 studies with 20678 patients (15781 with BMI < 25 kg/m 2 ; 4897 with BMI ≥ 25 kg/m 2 ). Overweight patients had significantly increased operation times [MD: -29.14; 95%CI: -38.14-(-20.21); P < 0.00001], blood loss [MD: -194.58; 95%CI: -314.21-(-74.95); P = 0.001], complications (RR: 0.75; 95%CI: 0.66-0.85; P < 0.00001), anastomosis leakages (RR: 0.59; 95%CI: 0.42-0.82; P = 0.002), and pancreatic fistulas (RR: 0.486; 95%CI: 0.34-0.63; P < 0.00001), whereas lymph node retrieval was decreased significantly in the overweight group (MD: 1.69; 95%CI: 0.75-2.62; P < 0.0001). In addition, overweight patients had poorer long-term survival (RR: 1.14; 95%CI: 1.07-1.20; P < 0.0001). No significant difference was detected for the mortality and length of hospital stay. CONCLUSION: This meta-analysis demonstrates that a high BMI not only increases the surgical difficulty and complications but also impairs the long-term survival of patients with gastric cancer.

关键词： Overweight Body mass index Gastric cancer Gastrectomy

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Passive activity enhances residual control ability in patients with complete spinal cord injury

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Neural Regeneration Research 2025年第8期20卷 2337-2347页

作者： Yanqing Xiao Mingming Gao Zejia He jia Zheng Hongming Bai jia-sheng Rao Guiyun Song Wei Song Xiaoguang Li Beijing Key Laboratory for Biomaterials and Neural Regeneration Beijing Advanced Innovation Center for Biomedical EngineeringSchool of Biological Science and Medical EngineeringBeihang UniversityBeijingChina Department of Rehabilitation Evaluation China Rehabilitation Research CenterBeijingChina Cardiac Center Beijing Children’s HospitalCapital Medical UniversityBeijingChina The State Key Laboratory of Virtual Reality Technology and Systems Beihang UniversityBeijingChina Department of Rehabilitation Engineering China Rehabilitation Science InstituteBeijingChina

Patients with complete spinal cord injury retain the potential for volitional muscle activity in muscles located below the spinal injury ***,because of prolonged inactivity,initial attempts to activate these muscles may not effectively engage any of the remaining neurons in the descending pathway.A previous study unexpectedly found that a brief clinical round of passive activity significantly increased volitional muscle activation,as measured by surface *** this study,we further explored the effect of passive activity on surface electromyographic signals during volitional control tasks among individuals with complete spinal cord *** patients with chronic complete thoracic spinal cord injury were *** electromyography data from eight major leg muscles were acquired and compared before and after the passive activity *** results indicated that the passive activity led to an increased number of activated volitional muscles and an increased frequency of *** the cumulative root mean square of surface electromyography amplitude for volitional control of movement showed a slight increase after passive activity,the difference was not statistically *** findings suggest that brief passive activity may enhance the ability to initiate volitional muscle activity during surface electromyography tasks and underscore the potential of passive activity for improving residual motor control among patients with motor complete spinal cord injury.

关键词： complete spinal cord injury cycle training epidural electrical stimulation motor training passive activity physiological state spinal cord circuit surface electromyography volitional control task

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Pancreatic stent improves the success rate of needle-knife papillotomy in patients with difficult biliary cannulation

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World Journal of Gastroenterology 2025年第1期31卷 58-67页

作者： mu-Hsien Lee Cheng-Hui Lin Chi-Huan Wu Yung-Kuan Tsou Kai-Feng Sung sheng-Fu Wang Nai-Jen Liu Department of Gastroenterology and Hepatology Chang Gung Memorial Hospital and Chang Gung University College of MedicineTaoyuan 33305Taiwan School of Medicine Chang Gung UniversityTaoyuan 33305Taiwan

BACKGROUND Needle-knife precut papillotomy(NKP)is typically performed ***,it remains unclear whether pancreatic stent(PS)placement can improve the outcomes of *** To explore whether PS placement improves the success rate of NKP in patients with difficult biliary *** This single-center retrospective study included 190 patients who underwent NKP between January 2017 and December 2021 after failed conventional biliary *** cases with incidental pancreatic duct cannulation during conventional biliary cannulation,the decision for pre-NKP PS placement was made at the endoscopist's *** primary outcome was the difference in the NKP success rate between patients with and without PS placement;the secondary outcome was the adverse event *** Among the 190 participants,82 received pre-NKP PS(PS-NKP group)whereas 108 did not[freehand or freehand NKP(FH-NKP)group].Post-NKP selective biliary cannulation was successful in 167(87.9%)patients,and the PS-NKP had a significantly higher success rate than the FH-NKP group(93.9%vs 83.3%,P=0.027).The overall adverse event rates were 7.3%and 11.1%in the PS-NKP and FH-NKP groups,respectively(P=0.493).A periampullary diverticulum(PAD)and significant intraoperative bleeding during NKP were independently associated with NKP failure;however,a pre-NKP PS was the only predictor of NKP *** the 44 participants with PADs,the PS-NKP group had a non-significantly higher NKP success rate than the FH-NKP group(87.5%and 65%,respectively;P=0.076).CONCLUSION PS significantly improved the success rate of NKP in patients with difficult biliary cannulation.

关键词： Difficult biliary cannulation Endoscopic retrograde cholangiopancreatography Needle-knife papillotomy Pancreatic stent Selective biliary cannulation

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Overexpression pattern,function,and clinical value of proteasome 26S subunit non-ATPase 6 in hepatocellular carcinoma

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World Journal of Clinical Oncology 2025年第2期16卷 76-93页

作者： sheng-sheng Zhou Yu-Ping Ye Yi Chen Da-Tong Zeng Guang-Cai Zheng Rong-Quan He Bang-Teng Chi Lei Wang Qian Lin Qin-Yan Su Yi-Wu Dang Gang Chen jia-Liang Wei Department of Medical Oncology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Clinical Laboratory The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Pathology The First Affiliated Hospital of Guangxi Medical UniversityNanning 530021Guangxi Zhuang Autonomous RegionChina Department of Pathology Redcross Hospital of Yulin CityYulin 537000Guangxi Zhuang Autonomous RegionChina Department of Surgery Redcross Hospital of Yulin CityYulin 537000Guangxi Zhuang Autonomous RegionChina

BACKGROUND In recent years,many studies have shown that proteasome 26S subunit non-ATPase 6(PSMD6)plays an important role in the occurrence and development of malignant ***,there are no reports on the evaluation of the potential role of PSMD6 in hepatocellular carcinoma(HCC).AIM To comprehensively evaluate the overexpression pattern and clinical significance of PSMD6 in HCC *** This study integrated PSMD6 mRNA expression profiles from 4672 HCC and 3667 non-HCC tissues,along with immunohistochemical scores from 383 HCC and adjacent tissues,to assess PSMD6 overexpression in *** regularly interspaced short palindromic repeats knockout technology evaluated PSMD6’s essential role in HCC cell *** enrichment analysis explored the molecular mechanism of PSMD6 abnormalities in *** sensitivity analysis and molecular docking analysed the effect of abnormal expression of PSMD6 on the drug sensitivity of HCC *** The results of 41 external and two internal datasets showed that PSMD6 mRNA(SMD=0.26,95%CI:0.09-0.42,P<0.05)and protein(SMD=2.85,95%CI:1.19-4.50,P<0.05)were significantly overexpressed in HCC *** integrated analysis results showed that PSMD6 had a significant overexpression pattern in HCC tissues(SMD=0.40,95%CI:0.15-0.66,P<0.05).PSMD6 knockout inhibited HCC cell growth(chronos scores<-1).Functional enrichment implicated ribosome biogenesis and RNA *** enrichment of signalling pathways such as RNA degradation,ribosomes,and chemical carcinogenesis—reactive oxygen *** sensitivity analysis and a molecular docking model showed that high expression of PSMD6 was associated with the tolerance of HCC cells to drugs such as ML323,sepantronium bromide,and *** PSMD6 effectively distinguished HCC tissues(AUC=0.75,95%CI:0.71-0.79).CONCLUSION This study was the first to discover that PSMD6 was overexpressed in HCC ***6 is essential for the growth of HCC cell

关键词： Hepatocellular carcinoma Proteasome 26S subunit non-ATPase 6 Clustered regularly interspaced short palindromic repeats Ribosome biogenesis RNA splicing

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Traveling Wave Characteristics Based Pilot Protection Scheme for Hybrid Cascaded HVDC Transmission Line

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Journal of Modern Power Systems and Clean Energy 2024年第3期12卷 971-980页

作者： Dalin mu sheng Lin Xiaopeng Li the School of Electrical Engineering Southwest Jiaotong UniversityChengdu 611756China the State Grid Sichuan Electric Power Research Institute Chengdu 610041China

The hybrid cascaded high-voltage direct current(HVDC)transmission system has various operation modes,and some operation modes have sharply increasing requirements for protection rapidity,while the traditional pilot differential protection(PDP)has poor rapidity,and even refuses to operate when faults occur on the DC ***,a novel pilot protection scheme based on traveling wave characteristics is ***,the adaptability of the traditional PDP applied in engineering is analyzed for different operation ***,the expressions of the forward traveling wave(FTW)and backward traveling wave(BTW)on the rectifier side and the inverter side are derived for different fault *** the theoretical derivation,the difference between the BTW and FTW on the rectifier side is less than zero,and the same is true on the inverter ***,in the event of an external fault of DC line,the difference between the BTW and FTW at nearfault terminal protection installation point is greater than ***,by summing over the product of the difference between BTW and FTW of the rectifier side and that of the inverter side,the fault identification criterion is *** simulation results show that the proposed pilot protection scheme can quickly and reliably identify the short-circuit faults of DC line in different operation modes.

关键词： Hybrid cascaded high-voltage direct current(HVDC)transmission system DC line operation mode pilot protection

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An experimental investigation of one-and two-degree of freedom VIV of cylinders

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Acta Mechanica Sinica 2013年第2期29卷 284-293页

作者： Zhuang Kang Lu-sheng jia College of Shipbuilding Harbin Engineering University CNOOC Research Institute

In the paper,an experiment investigation was conducted for one-and two-degree of freedom vortex-induced vibration（VIV） of a horizontally-oriented cylinder with diameter of 11 cm and length of 120 *** the experiment,the spring constants in the cross-flow and in-line flow directions were regulated to change the natural vibration frequency of the model *** was found that,in the one-degree of freedom VIV experiment,a ＂double peak＂ phenomenon was observed in its amplitude within the range of the reduced velocities tested,moreover,a ＂2T＂ wake appeared in the vicinity of the second *** the two-degree of freedom VIV experiment,the trajectory of cylinder exhibited a reverse ＂C＂ shape,i.e.,a ＂new moon＂ *** analysis of these data,it appears that,besides the non-dimensional in-line and cross-flow natural vibration frequency ratios,the absolute value of the natural vibration frequency of cylinder is also one of the important parameters affecting its VIV behavior.

关键词： One- and two-degree of freedom VIV “2T” wake “New moon” trajectory Natural vibration frequency ratio

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Manufacturing and testing of X-ray imaging components with high precision

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光学精密工程 2005年第5期13卷 620-625页

作者： HU jia sheng WU Xü School of Electronic and Information Engineering Dalian University of Technology Dalian 116024China College of Information Technology Dalian Maritime University Dalian 116026 China

In the latest 20 years, X-ray imaging technology has developed rapidly in order to meet the needs of X-ray photo-etching,spatial exploration technology, high-energy physics, procedure diagnosis of ICF,etc. Since refractive indices of materials in the X-ray region are lower than 1, and X-ray is strongly absorbed by materials, the characteristics of X-ray increase greatly difficulty to obtain X-ray image. Conventional imaging methods are hardly suitable to X-ray range. In general, grazing reflective imaging and coding aperture imaging methods have been adopted more and *** have designed a non-coaxial grazing reflective X-ray microscope which is composed of four spherical mirrors, in order to satisfy the requirement of the diagnosis of inertial confinement fusion (ICF). The four mirrors have the same radius of curvature. The radius of each mirror is 29 000 mm and the aperture is 30 mm×15 mm. Allowable tolerance of the radius is ≤0.2% and one of surface roughness (rms) is ≤0.6 nm. Evidently it is very difficult to fabricate and test such mirrors. In order to obtain eligible mirrors, we choose 18 mirror roughcasts and array them on a round disk according to format. The combined manufacturing method can ensure high accordant quality. The fabricated mirrors are tested by both templet and double round aperture methods. Radius errors of the mirrors is about 53 mm. The surface roughness (rms) of the mirrors is inspected by the relative interferometric equipment (WYKO) and atomic force microscope. Before and after coating the measured surface roughness is averagely 0.52 nm and 0.4 nm, respectively.

关键词： X光线图像质量评价纳米精度

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Mechanically strong,flexible,and multi-responsive phase change films with a nacre-mimetic structure for wearable thermal management

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Journal of Energy Chemistry 2022年第12期75卷 229-239,I0006页

作者： jiankang Zhang jiahui mu sheng Chen Feng Xu Beijing Key Laboratory of Lignocellulosic Chemistry Beijing Forestry UniversityBeijing 100083China

Phase change materials(PCMs)are a highly promising candidate for thermal energy storage owing to their large latent heat and chemical ***,their intrinsic brittle induces poor flexibility and low mechanical strength,which limits them use for wearable thermal ***,the electrical insulation and weak solar absorption make them lack multi-responsive ***,we report a facile strategy to synthesize mechanically strong and flexible multi-responsive phase change films by stirring an aqueous dispersion of cellulose nanofibrils(CNFs),MXene(Ti_(2)C_(3))nanosheets,and polyethylene glycol(PEG),followed by air-drying self-assembly and coating with hydrophobic *** hydrogen bonds and nacre-mimetic synergistic toughening networks formed by ternary CNFs,Ti_(2)C_(3)nanosheets,and PEG endow films with high mechanical strength(16.7 MPa)and strain(10.4%),which are 18.6 and 8.7 times higher than those of pure PEG film,*** films exhibit outstanding flexibility and do not crack or fracture even when bent,twisted,and folded into a complex small ***,the laminar structure formed by the self-assembly Ti_(3)C_(2)nanosheets enhances electrical conductivity(3.95 S/m)and solar absorption,affording excellent electro-thermal(68.3%–81.0%)and solarthermal(85.6%–90.6%)conversion efficiency,thus achieving multi-response to external stimuli(electron/solar radiation).In addition,the as-prepared films also deliver large latent heat(136.1 J/g),outstanding cyclic and shape stability,leak-free encapsulation even under compressed at above 5000 times its weight,excellent hydrophobicity(131.4°),and self-cleaning *** work paves the way for developing flexible,mechanically strong,and self-cleaning phase change film with multi-responsive function for wearable thermal management devices under high humidity condition.

关键词： Phase change materials Flexible Mechanically strong multi-responsive Wearable thermal management

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Uniform Exponential Attractor for Nonautonomous Partly Dissipative Lattice Dynamical System

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Acta Mathematica Sinica,English Series 2014年第8期30卷 1381-1394页

作者： sheng Fan ZHOU jia jia LOU Department of Mathematics Zhejiang Normal University Zhengzhou 63 Middle School

In this paper,we consider the existence of a uniform exponential attractor for the nonautonomous partly dissipative lattice dynamical system with quasiperiodic external forces.

关键词： Nonautonomous partly dissipative lattice systems uniform exponential attractor continuous process

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A Photometric Study of the W UMa-Type Contact Binary RZ Com

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Chinese Journal of Astronomy and Astrophysics 2008年第4期8卷 465-471页

作者： jia-jia He sheng-Bang Qian National Astronomical Observatories / Yunnan Observatory Chinese Academy of Sciences Kunming 650011 China United Laboratory of Optical Astronomy Chinese Academy of Sciences （ULOAC） Beijing 100012 China Graduate School of Chinese Academy of Sciences Beijing 100049 China

We present results of CCD photometric observations of the short-period W UMatype contact binary system, RZ Com. The light curve of the binary has changed from Wsubtype to A-subtype from 1998 to 2003, then back to W-subtype in 2004. An analysis was carried out using the 2003 version of the Wilson-Devinney code. It is confirmed that RZ Com is a low-degree, overcontact f = 20.1% （±7.4%） binary system with a high inclination of i = 81.°40 （＋0.°40）, and a mass ratio q = 2.351 （＋0.031）. Combining four newly determined times of light minimum with others in the literature, the variations in orbital period is examined. A small-amplitude oscillation （A=0.0065d）, with a period of 41.5 year, is discovered superimposed on a long-term increase at rate dP/dt = ＋3.97 × 10^-8d yr^-1. The period oscillation can be explained either by the light-time effect due to the presence of an unseen third body, or by cycles of magnetic activity on the components. Combining our photometric solution with the spectroscopic elements obtained by Mclean ＆ Hilditch, the absolute dimensions ofRZ Com are： M1 = 1.14 （±0.19）M⊙, M2 = 0.50 （±0.09）M⊙, R1 = 1.12 （±0.01）R⊙, R2 = 0.78 （＋0.01）R⊙ and A = 2.41 （±0.02）R⊙.

关键词： stars binaries close - stars binaries eclipsing - stars individual RZ Com

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