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World Journal of Clinical Cases 2024年第2期12卷 443-450页

作者： jia-ren wang Yue Hu Department of Neurology and Neurological Rehabilitation Shanghai Yangzhi Rehabilitation Hospital(Shanghai Sunshine Rehabilitation Center)Shanghai 201619China

BACKGROUND Patients with Parkinson's disease(PD)exhibit symptoms such as antecollis(AC)and camptocormia(CC).The pathology of these two conditions is ***,standard treatment methods have not been *** article reports the case of a 65-year-old female patient with AC and CC who was treated with central and peripheral interventions to alleviate *** SUMMARY We present the case of a 65-year-old female PD patient with AC and *** course of the disease was 5 *** was treated with rehabilitation strategies such as sensory tricks and trunk strength *** the inpatient period,we compared and analyzed the patient's gait,rehabilitation assessment scale score,and angles of her abnormal trunk posture in the first week,the third week,and the fifth *** patient's stride length increased,indicating that the patient's walking ability was *** Unified Parkinson's Disease Scale Part Three score and CC severity score ***,the score of the other scale *** addition,the patient showed significant improvements in AC,upper CC,and lower CC *** This case study suggested that sensory tricks and trunk strength training are beneficial and safe for patients with AC and CC.

关键词： Antecollis Camptocormia Parkinson's disease Sensory tricks Trunk strength training Case report

A Multi-faceted View of the X-Ray Spectral Variability in Seyfert Galaxy Ark 120

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Research in Astronomy and Astrophysics 2025年第1期25卷 228-239页

作者： Lu-Xin ren Jun-Xian wang jia-Lai Kang CAS Key Laboratory for Research in Galaxies and Cosmology Department of AstronomyUniversity of Science and Technology of China School of Astronomy and Space Science University of Science and Technology of China

Utilizing a range of techniques including multi-band light curves,softness ratio analysis,structure functions,rms spectra,cross-correlation functions,and ratios of spectra from different intervals,we present a comprehensive study of the complex X-ray spectral variability in Seyfert 1 galaxy Ark 120,through re-analyzing its six XMM-Newton observations taken between 2003 and *** find a clear“softer-when-brighter”trend in the 2–10 ke V power-law component over long timescales,with this trend being timescale dependent,as it is much weaker on shorter timescales,similar to that previously detected in NGC ***,a rare“harder-when-brighter”trend is observed during one exposure,indicating dynamic changes in the spectral variability behavior of the power-law *** exceptional exposure,with the spectral variability indeed marked by a power-law pivoting at an unusually low energy of～2 ke V,suggests intricate variations in the thermal Comptonization processes within the ***,when the data below 2 ke V are included,we identify that the soft excess component adds significant complexity to the spectral variability,such as evidenced by a transition from“harder-when-brighter”to“softer-when-brighter”during another single *** extra complexity arises because the variability of the soft excess sometimes follows and sometimes does not follow the changes in the power-law *** findings underscore the necessity of applying multiple analytic techniques to fully capture the multifaceted spectral variability of AGNs.

关键词： galaxies: active galaxies: Seyfert X-rays: galaxies

Phenanthrene perturbs hematopoietic development and causes hematopoietic defects in zebrafish

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Journal of Environmental Sciences 2025年第5期151卷 573-581页

作者： Lingyu ren Yue wang Ying ren Guangke Li Nan Sang College of Environment and Resource Research Center of Environment and HealthShanxi UniversityTaiyuan 030006China

Phenanthrene(Phe)is one of the common polycyclic aromatic hydrocarbons in the environment,and recent studies show that it can cause cardiac developmental toxicity and ***,it is still unknown whether it can affect the hematopoietic development in aquatic *** address this question,zebrafish(Danio rerio)were chronically exposed to Phe at different *** found that Phe caused structural damage to the renal tubules in the kidney,induced malformed erythrocytes in peripheral blood,and decreased the proportion of myeloid cells in adult zebrafish,suggesting possible negative impacts that Phe posed to hematopoietic ***,using in situ hybridization technology,we found that Phe decreased the expression of primitive hematopoietic marker genes,specifically gata1 and pu.1,accompanied by an obstruction of primitive erythrocyte ***,Phe impaired definitive hematopoiesis,increased aberrations of the transient hematopoietic site(PBI),and reduced the generation of hematopoietic stem cells,ultimately influencing the number of erythrocytes and myeloid *** findings suggested that Phe could induce hematopoietic toxicity in zebrafish embryos and pose unknown ecological risks.

关键词： Phenanthrene Zebrafish Hematopoietic development Hematopoietic defect

Molecular-based porous polymers with precise sites for photoreduction of carbon dioxide

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Chinese Chemical Letters 2025年第1期36卷 201-213页

作者： Wei-jia wang Kaihong Chen College of Biological and Chemical Engineering Zhejiang University of Science and TechnologyHangzhou 310023China The Institute of Green Chemistry and Engineering School of Chemistry and Chemical EngineeringNanjing UniversitySuzhou 215163China

Photocatalytic CO_(2)reduction reaction(CO_(2)RR)is one of the promising strategies for sustainably producing solar *** precise identification of catalytic sites and the enhancement of photocatalytic CO_(2)conversion is imperative yet quite *** critical review summarizes recent advances in porous photo-responsive polymers,including covalent organic frameworks(COFs),covalent triazine frameworks(CTFs),and conjugated microporous polymers(CMPs),those can be rationally designed from the molecular level for visible-light-driven photocatalytic CO_(2)***,special emphasis is placed on how the well-defined active sites on these polymers can influence their properties and photocatalytic *** precise regulation and control of microenvironments and electronic properties of metal active centers are crucial for boosting catalytic efficiency and selectivity,as well as for the design of better photocatalysts for CO_(2)reduction.

关键词： Carbon dioxide reduction Photocatalysis Porous polymers Well-defined catalytic sites Molecular level

Exploring the diversity of dissolved organic matter(DOM)properties and sources in different functional areas of a typical macrophyte-derived lake combined with optical spectroscopy and FT-ICR MS analysis

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Journal of Environmental Sciences 2025年第1期147卷 462-473页

作者： Kun wang Haoyu ren Shengwu Yuan Xia jiang Pengfei wang College of Water Sciences Beijing Normal UniversityBeijing 100875China National Engineering Laboratory of Lake Pollution Control and Ecological Restoration Chinese Research Academy of Environmental SciencesBeijing 100012China

Lake Baiyangdian is one of China’s largest macrophyte-derived lakes,facing severe challenges related to water quality maintenance and eutrophication *** organic matter(DOM)was a huge carbon pool and its abundance,property,and transformation played important roles in the biogeochemical cycle and energy flow in lake *** this study,Lake Baiyangdian was divided into four distinct areas:Unartificial Area(UA),Village Area(VA),Tourism Area(TA),and Breeding Area(BA).We examined the diversity of DOM properties and sources across these functional *** findings reveal that DOM in this lake is predominantly composed of protein-like substances,as determined by excitation-emission matrix and parallel factor analysis(EEM-PARAFAC).Notably,the exogenous tyrosine-like component C1 showed a stronger presence in VA and BA compared to UA and ***-resolution mass spectrometry(FT-ICR MS)unveiled a similar DOM molecular composition pattern across different functional areas due to the high relative abundances of lignan compounds,suggesting that macrophytes significantly influence the material structure of *** properties exhibited specific associations with water quality indicators in various functional areas,as indicated by the Mantel *** connections between DOM properties and NO_(3)-N andNH3-Nwere more pronounced in VA and BA than in UA and *** results underscore the viability of using DOM as an indicator for more precise and scientific water quality management.

关键词： Dissolved organic matter Fluorescence property Molecular composition Source

Impact of antibiotics on the efficacy of immune checkpoint inhibitors in the treatment of primary liver cancer

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Liver Research 2022年第3期6卷 175-180页

作者： jia-ren wang Rui-Ning Li Chao-Yi Huang Chang Hong Qi-Mei Li Lin Zeng Jing-Zhe He Cheng-Yi Hu Hao Cui Li Liu Lu-Shan Xiao Big Data Center Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongChina Department of Infectious Diseases Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdongChina Department of Infectious Diseases Guangzhou First People's HospitalGuangzhouGuangdongChina

Background and aim:Immune checkpoint inhibitors(ICIs)are widely used in the treatment of liver ***,the interaction with other drugs may change the efficacy of *** studies investigated the effects of antibiotics(ATBs)on the efficacy of immunotherapy and the survival of patients with primary liver cancer receiving *** study aimed to explore the impact of ATBs on the efficacy of immunotherapy in patients with primary liver ***:In total,215 patients with primary liver cancer who received ICIs from June 2018 to October 2020 were included for retrospective *** progression-free survival(PFS),disease control rate(DCR),and overall survival(OS)were compared between patients treated with and without ATBs within 30 days before and after ***:No significant differences in PFS(P=0.376)and OS(P=0.121)were found between patients treated with and without *** and multivariate analyses showed that using ATBs was not associated with PFS,DCR,and ***:The use of ATBs within 30 days before and after immunotherapy in patients with primary liver cancer had no adverse effects on PFS,DCR,and OS.

关键词： Immunotherapy Immune checkpoint inhibitors(ICIs) Primary liver cancer Antibiotics(ATBs)

Optimizing cooling approach of spiral coil for an electromagnetic steel teeming system of ladle in continuous casting production

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Journal of Iron and Steel Research International 2025年第1期32卷 85-94页

作者： Ming He Qing-wei wang Li-jia Zhao wang-zhong Mu Xing-an Liu Qiang wang College of Horticulture Shenyang Agricultural UniversityShenyang110866LiaoningChina Key Laboratory of Electromagnetic Processing of Materials(Ministry of Education) Northeastern UniversityShenyang110819LiaoningChina Key Laboratory of Protected Horticulture(Ministry of Education) Shenyang Agricultural UniversityShenyang110866LiaoningChina Department of Materials Science and Engineering KTH Royal Institute of TechnologyStockholm10044Sweden

To address the current issues with the conventional slide gate system utilized in the steel teeming process,a unique electromagnetic induction controlled automated steel teeming(EICAST)technology has been *** means of spiral coil in this technology is directly related to its service ***,heat transfer processes of air cooling and spray cooling were compared and ***,the impacts of water temperature,water flow rate and air flow rate were examined in order to maximize the spray cooling *** maintain coil temperature at a low value consistently throughout the entire thermal cycle process of the ladle,a combined cooling mode was finally *** simulation was applied to examine the coil temperature variation with different cooling systems and *** coil operation,spray cooling is said to be more *** controlling the water flow rate and air flow rate,the spray cooling effect is ***,water temperature has little or no impact when using spray *** cooling during the secondary refining process and spray cooling prior to coil operation are combined to further lower coil *** the direction of the spray cooling is from bottom to top,the coil temperature is lowered below 165℃.A practical induction coil cooling plan was provided for the EICAST technology’s production process.

关键词： Electromagnetic induction controlled automated steel teeming technology Spiral coil Spray cooling Heat transfer Continuous casting

Impact of coking plant to heavy metal characteristics in groundwater of surrounding areas:Spatial distribution,source apportionment and risk assessments

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Journal of Environmental Sciences 2025年第3期149卷 688-698页

作者： Congqing wang Wanjun wang Chaowang Shixing ren Yingjun Wu Meicheng Wen Guiying Li Taicheng An Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control Guangdong Hong Kong-Macao Joint Laboratory for Contaminants Exposure and HealthInstitute of Environmental Health and Pollution ControlGuangdong University of TechnologyGuangzhou 510006China Guangzhou Key Laboratory Environmental Catalysis and Pollution Control Key Laboratory of City Cluster Environmental Safety and Green developmentSchool of Environmental Science and EngineeringGuangdong University of TechnologyGuangzhou 510006China

Coking industry is a potential source of heavy metals(HMs)***,its impacts to the groundwater of surrounding residential areas have not been well *** study investigated the pollution characteristics and health risks of HMs in groundwater nearby a typical coking *** HMs including Fe,Zn,Mo,As,Cu,Ni,Cr,Pb and Cd were *** average concentration of total HMswas higher in the nearby area(244.27μg/L)than that of remote area away the coking plant(89.15μg/L).The spatial distribution of pollution indices including heavy metal pollution index(HPI),Nemerow index(NI)and contamination degree(CD),all demonstrated higher values at the nearby residential areas,suggesting coking activity could significantly impact the HMs distribution *** sources of HMs were identified by Positive Matrix Factorization(PMF)model,which indicated coal washing and coking emission were the dominant sources,accounted for 40.4%,and 31.0%,*** ingestionwas found to be the dominant exposure pathway with higher exposure dose to children than *** quotient(HQ)values were below 1.0,suggesting negligible non-carcinogenic health risks,while potential carcinogenic risks were from Pb and Ni with cancer risk(CR)values>10−*** Carlo simulation matched well with the calculated results with HMs concentrations to be the most sensitive *** study provides insights into understanding how the industrial coking activities can impact the HMs pollution characteristics in groundwater,thus facilitating the implement of HMs regulation in coking industries.

关键词： Coking industry Heavy metal Groundwater Spatial distribution Source apportionment Monte Carlo simulation

Upcycling of polyphenylene oxide into 2,6-dimethyl aniline via depolymerization and amination over a Pt/CeO_(2) catalyst

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Science China Chemistry 2025年第2期68卷 520-525页

作者： Shengchao jia Wenke Zhao Xiaohui Liu Yong Guo Yanqin wang State Key Laboratory of Green Chemical Engineering and Industrial Catalysis Research Institute of Industrial CatalysisSchool of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China Shanghai Key Laboratory of Functional Materials Chemistry School of Chemistry and Molecular EngineeringEast China University of Science and TechnologyShanghai 200237China

Upcycling of plastic waste into N-containing compound is a novel and attractive strategy for its disposal and will opens up a promising direction for the production of value-added ***,an efficient strategy for the depolymerization-amination of polyphenylene oxide(PPO)into 2,6-dimethyl aniline is developed over a simple Pt/CeO_(2) *** C–O linkages of PPO can be selectively broken,producing 2,6-dimethyl phenol and then hydrogenated and aminated to 2,6-dimethyl cyclohexylamine over the Pt/CeO_(2) ***,2,6-dimethyl aniline was produced with high selectivity through the dehydrogenation of 2,6-dimethyl cyclohexylamine in the same *** can be used as the hydrogen-acceptor in the dehydrogenation step and enhance the selectivity of target *** N-containing compound,2,6-dimethyl aniline,is obtained and separated after HCl ***,the Pt/CeO_(2) catalyst exhibit remarkable stability and can sustainably catalyze the synthesis of 2,6-dimethyl aniline in several cycles.

关键词： PPO depolymerization-amination 2,6-dimethyl aniline Pt/CeO_(2)

Statistical analysis on the validity of the cold plasma approximation for chorus waves based on Van Allen Probe observations and their effects on radiation belt electrons

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Earth and Planetary Physics 2025年第1期9卷 159-170页

作者： AoJun ren jiang Yu Jing wang ZuZheng Chen XiaoMan Liu Planetary Environmental and Astrobiological Research Laboratory(PEARL) School of Atmospheric SciencesSun Yat-sen UniversityZhuhai Guangdong 519000China

Theoretical analysis has demonstrated that the dispersion relation of chorus waves plays an essential role in the resonant interaction and energy transformation between the waves and magnetospheric *** quantitative analyses often simplified the chorus dispersion relation by using the cold plasma ***,the applicability of the cold plasma assumption is doubtful,especially during geomagnetic *** here present a systematic statistical analysis on the validity of the cold plasma dispersion relation of chorus waves based on observations from the Van Allen Probes over the period from 2012 to *** statistical results show that the observed magnetic field intensities deviate substantially from those calculated from the cold plasma dispersion relation and that they become more pronounced with an increase in geomagnetic activity or a decrease in background plasma *** region with large deviations is mainly concentrated in the nightside and expands in both the radial and azimuthal directions as the geomagnetic activity increases or the background plasma density *** addition,the bounce-averaged electron scattering rates are computed by using the observed and cold plasma dispersion relation of chorus *** with usage of the cold plasma dispersion relation,usage of the observed dispersion relation considerably lowers the minimum resonant energy of electrons and lowers the scattering rates of electrons above tens of kiloelectronvolts but enhances those ***,these differences are more pronounced with the enhancement of geomagnetic activity or the decrease in background plasma density.

关键词： chorus waves cold plasma approximation dispersion relations scattering rates