检索结果-南通市图书馆

Frontiers of physics 2020年第4期15卷 133-151页

作者： Yong-jia Wang qing-Feng li School of Science Huzhou UniversityHuzhou 313000China Institute of Modern Physics Chinese Academy of SciencesLanzhou 730000China

The equation of state(EOS)of nuclear matter,i.e.,the thermodynamic relationship between the binding energy per nucleon,temperature,density,as well as the isospin asymmetry,has been a hot topic in nuclear physics and astrophysics for a long *** knowledge of the nuclear EOS is essential for studying the propertics of muclei,the structure of neutron stars,the dynamics of heavy ion collision(HIC),as well as neutron star *** offers a unique way to create muclear matter with high density and isospin asymmetry in terrestrial laboratory,but the formed dense nuclear matter exists only for a very short period,one cannot measure the nuclear EOS directly in ***,transport models which often incorporate phenomenological potentials as an input are utilized to deduce the EOS from the comparison with the observables mcasured in *** ultrarelativistic quantum molecular dynamics(UrQMD)model has been widely employed for investigating HIC from the Fermi energy(40 MeV per nucleon)up to the CERN Large Hadron Collider energies(TeV).With further improvement in the nmuclear mean-field potential term,the collision term,and the cluster recognition term of the UrQMD model,the newly measured collective flow and nuclear stopping data of light charged particles by the FOPI Collaboration can be *** this article we highlight our recent results on the studies of the muclear EOS and the muclear symmetry energy with the UrQMD *** opportunities and challenges in the extraction of the nuclear EOS from transport models and HIC experiments are discussed.

关键词： muclear equation of state symmetry energy heavy ion collision transport model

血瘀证型冠状动脉粥样硬化性心脏病的半导体激光仪治疗:随机、仿盲、平行对照

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中国临床康复 2006年第39期10卷 36-38页

作者：熊航孙兰军贾力箐赵英强郑偕扣张晓莉王瑞华天津中医药大学 2004级学生天津市300193 天津中医药大学第二附属医院心内2科北京健鹤宝科贸有限公司北京市100000

目的:采用随机、仿盲、平行对照的原则,观察半导体激光治疗对血瘀证型冠状动脉粥样硬化性心脏病(简称冠心病)的临床疗效和不良反应。方法:①参照2000年中华医学会心血管病学分会、中华心血管病杂志编辑委员会制定的《不稳定性心绞痛诊... 详细信息

目的:采用随机、仿盲、平行对照的原则,观察半导体激光治疗对血瘀证型冠状动脉粥样硬化性心脏病(简称冠心病)的临床疗效和不良反应。方法:①参照2000年中华医学会心血管病学分会、中华心血管病杂志编辑委员会制定的《不稳定性心绞痛诊断和治疗建议》和《中药新药治疗胸痹(冠心病心绞痛)的临床研究指导原则》诊断标准,选择2006-01/02天津中医药大学第二附属医院门诊收治的血瘀证型冠心病患者60例,随机数字表法分为半导体激光治疗组、常规治疗组,30例/组。②常规治疗组使用硝酸酯类、β受体阻滞剂、阿司匹林等常规冠心病心绞痛药物进行治疗,其原来使用的剂量不做任何改变,疗程14d。半导体激光治疗组在常规治疗组的基础上,每天采用半导体激光治疗仪(由北京鹤宝科贸有限公司研制,经国家食品药品监督管理局审查批准,批号20050076)选择波长为650nm的半导体激光作为激光源,以3～5mW的输出功率进行鼻腔内照射,30min/次,1次/d,疗程14d。③观察治疗前后两组患者的心率、血压、中医证候积分、心绞痛症状、治疗心绞痛药物停减率等指标,同时检查心电图。结果:按意向处理分析,60例血瘀证型冠心病患者均进入结果分析。两组患者各项指标临床治疗效果的比较:半导体激光治疗组与常规治疗组心绞痛、心电图总有效率均基本相似(63.3%,50%;50%,36.7%;P均>0.05),但半导体激光治疗组中医证候总有效率明显高于常规治疗组(83.3%,63.3%,P<0.05)。两组在治疗过程中均无毒副作用及不良反应。结论:半导体激光治疗仪对血瘀证型冠心病患者有明显的临床干预效果,能够明显改善神倦乏力等中医证候症状。

关键词：激光/治疗应用冠状动脉疾病心绞痛血瘀

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干细胞的趋电性迁移及机制

中国组织工程研究 2025年第23期29卷 4984-4992页

作者：韩芳舒晴贾绍辉田峻武汉体育学院运动医学院湖北省武汉市430079 武汉大学中南医院骨科康复科湖北省武汉市430071

背景:随着对干细胞技术研究的深入,如何使其准确归巢成为临床应用中的一大难题。除药物和趋化因子等信号的诱导外,电场也被广泛应用于指导干细胞的定向迁移,并可增强其迁移速度和定向性。目的:旨在分析总结电场对干细胞迁移特性的影响,... 详细信息

背景:随着对干细胞技术研究的深入,如何使其准确归巢成为临床应用中的一大难题。除药物和趋化因子等信号的诱导外,电场也被广泛应用于指导干细胞的定向迁移,并可增强其迁移速度和定向性。目的:旨在分析总结电场对干细胞迁移特性的影响,同时综述可能的作用机制。方法:通过检索Pub Med和中国知网数据库,收集截至2024年3月的相关文献,英文检索词:“stem cells,direct current electric field,pulsed electric field,migration,electric field device,mechanism”;中文检索词:“干细胞,直流电场,脉冲电场,迁移,电场装置,机制”。排除不能获取全文和与主题无关的文献。结果与结论:根据筛选要求共纳入58篇文献,包括中文文献15篇及英文文献43篇。文献以脂肪间充质干细胞、骨髓间充质干细胞、神经干细胞、表皮干细胞、人胚胎干细胞和人诱导性多功能干细胞为研究对象,在迁移装置中研究电场的不同参数对上述干细胞迁移的影响及其机制。(1)电场作为一种简单、无创且稳定的干预方式在指导干细胞定向迁移的过程中起着积极作用;(2)不同类型的干细胞发生趋电性迁移的方向不同,同时大部分干细胞的迁移速度和定向性是随着电场强度增加而增加的;(3)不同的电场装置在观测干细胞迁移时的侧重点不同,可根据实验目的而择优选择相关装置;(4)不同干细胞趋电性迁移的机制不完全相同,多数干细胞迁移过程中有MAPK通路、ROCK活化以及PI3K功能的参与,同时还有其他蛋白质复合物与信号通路参与调控该过程;(5)除电场参数不同之外,细胞本身的衰老情况和培养环境也会对趋电性迁移的结果产生影响。总而言之,电场作为一种影响干细胞迁移特性的重要信号,与其他新兴材料结合在组织工程应用中展现出了一定的潜力,有望在指导干细胞归巢方面发挥更加重要的作用,促进骨组织再生和修复以及神经系统、自身免疫系统以及肿瘤等疾病的研究取得更大的突破。

关键词：干细胞电场趋电性迁移机制归巢效应物理因子电场装置细胞衰老培养环境

苯并[a]芘对神经胶质细胞中胰岛素降解酶与脑啡肽酶表达的影响

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北京大学学报（医学版） 2018年第3期50卷 401-407页

作者：张慧峰黄焕焕赵雨佳李清如祁宇泽周辉北京大学公共卫生学院劳动卫生与环境卫生学系北京100191

目的:探讨苯并[a]芘[benzo(a)pyrene,Ba P]对神经胶质细胞中具有β-淀粉体(β-amyloid,Aβ)清除作用的胰岛素降解酶(insulin-degrading enzyme,IDE)及脑啡肽酶(neprilysin,NEP)表达的影响。方法:制备新生SD大鼠原代神经胶质细胞混合培... 详细信息

目的:探讨苯并[a]芘[benzo(a)pyrene,Ba P]对神经胶质细胞中具有β-淀粉体(β-amyloid,Aβ)清除作用的胰岛素降解酶(insulin-degrading enzyme,IDE)及脑啡肽酶(neprilysin,NEP)表达的影响。方法:制备新生SD大鼠原代神经胶质细胞混合培养体系,接受不同浓度的Ba P、Aβ1-42寡聚体、Aβ1-42纤维体单独或联合处理24 h后,采用细胞增殖-毒性检测试剂盒测定细胞存活率。随机分为对照组、Ba P(2.00μmol/L)组、Aβ1-42(20.00 mg/L)寡聚体组、Ba P+Aβ1-42寡聚体组、Aβ1-42(20.00 mg/L)纤维体组、Ba P+Aβ1-42纤维体组,其中Ba P均为预处理12 h后再与不同聚集状态的Aβ1-42共同作用。进一步采用实时荧光定量PCR及蛋白质免疫印迹技术检测体系中IDE、NEP的mRNA和蛋白表达水平。结果:20.00μmol/L及以下浓度的Ba P处理,20.00、40.00 mg/L的Aβ1-42寡聚体或Aβ1-42纤维体单独处理,Ba P与Aβ1-42寡聚体或Ba P与Aβ1-42纤维体联合处理对神经胶质细胞的存活率均无明显影响。与对照组相比,Ba P单独处理组中IDE、NEP的mRNA和蛋白水平均未明显改变;而Aβ1-42寡聚体单独作用可明显上调IDE的mRNA及蛋白水平(P<0.05),同时Ba P预处理可显著抑制Aβ1-42寡聚体作用引起的IDE表达水平上调(P<0.05);另一方面,Aβ1-42纤维体在单独处理或有Ba P预处理情况下,IDE、NEP的mRNA和蛋白水平均未发生明显改变。结论:在对细胞存活率无明显影响的前提下,Ba P预处理显著抑制了Aβ寡聚体作用后的IDE表达水平上调,提示苯并[a]芘可能干扰Aβ寡聚体降解途径导致Aβ增多聚集,进而可能促进认知功能降低及阿尔兹海默病的形成。

关键词：苯并[a]芘胰岛素降解酶脑啡肽酶神经胶质

Advanced Functional Electromagnetic Shielding Materials:A Review Based on Micro‑Nano Structure Interface Control of Biomass Cell Walls

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Nano-Micro Letters 2025年第1期17卷 98-134页

作者： Yang Shi Mingjun Wu Shengbo Ge jianzhang li Anoud Saud Alshammari Jing Luo Mohammed A.Amin Hua Qiu Jinxuan jiang Yazeed M.Asiri Runzhou Huang Hua Hou Zeinhom M.El‑Bahy Zhanhu Guo Chong jia Kaimeng Xu Xiangmeng Chen Co‑Innovation Center of Efficient Processing and Utilization of Forest Resources College of Materials Science and EngineeringNanjing Forestry UniversityNanjing 210037People’s Republic of China State Key Laboratory of Efficient Production of Forest Resourced Beijing Forestry UniversityQinghua East Road 35Haidian DistrictBeijing 100083People’s Republic of China Department of Physics Faculty of Sciences‑ArarNorthern Border UniversityArar 91431Saudi Arabia Department of Chemistry College of ScienceTaif UniversityP.O.Box 1109921944 TaifSaudi Arabia Shaanxi Key Laboratory of Macromolecular Science and Technology School of Chemistry and Chemical EngineeringNorthwestern Polytechnical UniversityXi’anShaanxi 710072People’s Republic of China Integrated Composites Lab Department of Mechanical and Construction EngineeringNorthumbria UniversityNewcastle Upon Tyne NE18STUK College of Materials Science and Engineering Taiyuan University of Science and TechnologyTaiyuan 030024People’s Republic of China Department of Chemistry Faculty of ScienceAl-Azhar UniversityNasr CityCairo 11884Egypt Yunnan Provincial Key Laboratory of Wood Adhesives and Glued Products International Joint Research Center for Biomass MaterialsSouthwest Forestry UniversityKunming 650224People’s Republic of China School of Science Henan Agricultural UniversityZhengzhou 450002People’s Republic of China

Research efforts on electromagnetic interference(EMI)shielding materials have begun to converge on green and sustainable biomass *** materials offer numerous advantages such as being lightweight,porous,and *** to their porous nature,interfacial compatibility,and electrical conductivity,biomass materials hold significant potential as EMI shielding *** concerted efforts on the EMI shielding of biomass materials have been reported,this research area is still relatively new compared to traditional EMI shielding *** particular,a more comprehensive study and summary of the factors influencing biomass EMI shielding materials including the pore structure adjustment,preparation process,and micro-control would be *** preparation methods and characteristics of wood,bamboo,cellulose and lignin in EMI shielding field are critically discussed in this paper,and similar biomass EMI materials are summarized and *** composite methods and fillers of various biomass materials were *** paper also highlights the mechanism of EMI shielding as well as existing prospects and challenges for development trends in this field.

关键词： Biomass materials Electromagnetic interference shielding Micro-nano structure interface control Conductivity

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L-阿拉伯糖的功效研究进展

食品与发酵科技 2017年第5期53卷 76-79页

作者：孟庆佳李颂董志忠中粮营养健康研究院有限公司北京102209 营养健康与食品安全北京市重点实验室北京102209 老年营养食品研究北京市工程实验室北京102209

L-阿拉伯糖是一种戊醛糖,也是一种"低热量代糖",其甜度大约为蔗糖的50%左右。L-阿拉伯糖在小肠内具有抑制蔗糖吸收的作用。本文综述了近年L-阿拉伯糖对由蔗糖分解导致的减少血糖升高的作用以及促进肠道益生菌生长和调节脂代谢等健康功... 详细信息

L-阿拉伯糖是一种戊醛糖,也是一种"低热量代糖",其甜度大约为蔗糖的50%左右。L-阿拉伯糖在小肠内具有抑制蔗糖吸收的作用。本文综述了近年L-阿拉伯糖对由蔗糖分解导致的减少血糖升高的作用以及促进肠道益生菌生长和调节脂代谢等健康功效的研究和应用。

关键词： L-阿拉伯糖蔗糖血糖糖尿病益生菌

Bullous pemphigoid associated with acquired hemophilia A: A case report

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World Journal of Clinical Cases 2025年第4期13卷 28-33页

作者： Su-Ye Hu Meng-Can li Zi-jia Hao Xu-Ya Chai Pei-Sai li Yang liu li-Xia liu Ying Xu Pan-Pan Yang ling-E li Department of Dermatology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina Graduate School Hebei University of Traditional Chinese MedicineShijiazhuang 050051Hebei ProvinceChina Department of Pathology Shijiazhuang Traditional Chinese Medicine HospitalShijiazhuang 050051Hebei ProvinceChina

BACKGROUND Acquired hemophilia A (AHA) is a rare and potentially severe bleeding disordercaused by circulating autoantibodies against factor Ⅷ (FⅧ). In approximately50% of the patients, the condition is associated with autoimmune diseases,cancers, medication use, pregnancy, and the post-partum period. Bullous pemphigoid(BP) is a chronic autoimmune subepidermal blistering disease associatedwith tissue-bound and circulating autoantibodies against BP antigens 180 (BP180)and 230 (BP230). AHA-associated BP has a high mortality rate;hence, the understandingof this disease must *** SUMMARY A 69-year-old man presented with erythema, blisters, blood blisters, and crustsaccompanied by severe pruritus for more than 20 days, and ecchymosis andswelling on his left upper arm for 3 days. Pathological examination revealed asubepidermal blister that contained eosinophils. Laboratory tests showed that theBP180 autoantibody levels had increased, isolated activated partial thromboplastintime was notably prolonged (115.6 s), and coagulation FⅧ activity wasextremely low (lity rate. Therefore, its timely diagnosis and effectivetreatment are necessary.

关键词： Bullous pemphigoid Acquired hemophilia A Acquired hemophilia A FactorⅧ Case report

达比加群酯联合尼可地尔治疗经皮冠状动脉介入治疗术后心绞痛的效果及对N末端B型利钠肽前体与可溶性CD105的影响

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中国药物经济学 2023年第9期18卷 71-74,79页

作者：陈传军王静贾利清曲涛内蒙古包钢医院/内蒙古医科大学第三附属医院心内科内蒙古包头014010

目的探讨尼可地尔联合达比加群酯治疗经皮冠状动脉介入治疗(PCI)术后心绞痛的疗效及对N末端B型利钠肽前体(NT-proBNP)、可溶性CD105(sCD105)水平的影响。方法选取2018年4月至2022年12月内蒙古包钢医院收治的PCI术后心绞痛患者70例作为... 详细信息

目的探讨尼可地尔联合达比加群酯治疗经皮冠状动脉介入治疗(PCI)术后心绞痛的疗效及对N末端B型利钠肽前体(NT-proBNP)、可溶性CD105(sCD105)水平的影响。方法选取2018年4月至2022年12月内蒙古包钢医院收治的PCI术后心绞痛患者70例作为研究对象,随机分为对照组和观察组,各35例。对照组服用尼可地尔治疗,观察组服用尼可地尔联合达比加群酯治疗。记录两组患者治疗前后心绞痛发作次数和持续时间,评价临床疗效和安全性,同时检测患者NT-proBNP、sCD105水平。结果治疗后两组心绞痛发作次数、持续时间明显减少(P0.05);两组不良反应发生率比较差异无统计学意义(P>0.05)。结论PCI术后心绞痛采用尼可地尔联合达比加群酯治疗,具有较好的抗心绞痛效果,出血风险低,并可有效改善心脏损伤标志物,但对sCD105无明显影响。

关键词：尼可地尔达比加群酯经皮冠状动脉介入治疗后心绞痛 N末端B型利钠肽前体可溶性CD105

Solar trough receiver with V-grooved light traps for efficiency improvement

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Science China Technological Sciences 2025年第1期 146-156页

作者： Bin liU qing li Yu QIU School of Energy Science and Engineering Central South University

Parabolic trough collector is a promising technology for both domestic and industrial heat supplies. To enhance the collector efficiency, a modified trough receiver with dozens of V-grooved light traps incorporated into its lower-half absorber was introduced. For assessing the performance of this receiver, a solar-thermal-stress coupled model was established. Using this model, firstly, the effects of the V-grooved light traps were investigated. The results reveal that, compared to the conventional trough receiver, the modified trough receivers equipped with different traps can reduce their optical losses by 81.9–138.0 Wm-1（i.e., 15.0%–25.2%）, improving their optical efficiencies by 1.60%–2.69%. However, these traps also result in increased thermal loss from the receiver. Therefore, there is no single optimal modified trough receiver that consistently outperforms all other receivers across all possible conditions. Nonetheless, the MTR30-3 and MTR60-3 receivers emerge as the optimized choices due to their better solar-thermal performance. Subsequently, performance evaluation reveals that the two optimized receivers can enhance the receiver efficiencies within the typical solar irradiance range by 0.02%–2.65% and 0.05%–1.70% when the inlet fluid temperatures are below 488 and 523 K, respectively. Consequently, the collector efficiencies can be improved by 0.02%–2.49% and 0.05%–1.60%, respectively. Additionally, thermal stress analysis verifies that the two optimized receivers remain within safe limits under all typical conditions. Given that the heating temperature of a typical solar collector for domestic or industrial heat supply is typically below 523 K, the integration of the two optimized receivers has the capability to effectively enhance the overall collector efficiency.

关键词：

煤粉燃烧性与工业分析、着火温度的相关性研究

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中国安全生产科学技术 2012年第4期8卷 40-43页

作者：金龙哲段健欧盛南贾立庆北京科技大学土木与环境工程学院北京100083 兖矿新疆矿业公司硫磺沟煤矿分公司昌吉831114

喷吹煤粉燃烧性是生产中的一个重要参数,实时掌握原煤燃烧性的波动变化对保证喷煤的安全和稳定十分必要。直接测量煤粉燃烧性的方法成本高,时间长,操作复杂,不利于生产应用;采用测定煤的工业分析和着火温度的方法简单易行,应用范围广泛... 详细信息

喷吹煤粉燃烧性是生产中的一个重要参数,实时掌握原煤燃烧性的波动变化对保证喷煤的安全和稳定十分必要。直接测量煤粉燃烧性的方法成本高,时间长,操作复杂,不利于生产应用;采用测定煤的工业分析和着火温度的方法简单易行,应用范围广泛。该文针对某炼铁厂的15种原煤,进行了工业分析和着火温度的实验研究,引入了统计学中相关系数的概念对数据进行了处理分析,实验证明煤的挥发分和着火温度与煤粉的燃烧性高度线性相关,此方法为利用两参数间接分析煤粉燃烧性提供了理论基础。

关键词：喷吹煤粉燃烧性挥发分着火温度相关系数