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Predicted interfacial thermal conductance and thermal conductivity of diamond/Al composites with various interfacial coatings

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Rare Metals 2011年第5期30卷 544-549页

作者： LIANG Xuebing jia Chengchang chu Ke CHEN Hui School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China General Research Institute for Nonferrous Metals （GRINM） Beijing 100083 China

The interfacial thermal conductance （ITC） and thermal conductivity （TC） of diamond/Al composites with various coatings were theoretically studied and discussed. A series of predictions and numerical analyses were performed to investigate the effect of thickness, sound velocity, and other parameters of coating layers on the ITC and TC. It is found that both the ITC and TC decline with increasing coating thickness, especially for the coatings with relatively low thermal conductivity. Nevertheless, if the coating thickness is close to zero, or quite a small value, the ITC and TC are mainly determined by the constants of the coating material. Under this condition, coatings such as Ni, TiC, Mo 2 C, SiC, and Si can significantly improve the ITC and TC of diamond/Al composites. By contrast, coatings like Ag will exert the negative effect. Taking the optimization of interfacial bonding into account, conductive carbides such as TiC or Mo 2 C with low thickness can be the most suitable coatings for diamond/Al composites.

关键词： metallic matrix composites coatings diamonds thermal conductivity interfacial thermal conductance

Removal of iron from ilmenite by KOH leaching-oxalate leaching method

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Rare Metals 2010年第1期29卷 9-15页

Oxalic acid was used for the removal of iron from the intermediates of ilmenite leached by KOH liquor. Various parameters, such as pH, temperature, initial oxalate concentration, and illumination were investigated. Meanwhile, it was found that orthorhombic crystal Ti2O2（OH）2（C2O4）-H2O formed as the leaching proceeded. Scanning electronic microscope （SEM） images implied that the formation of Ti2O2（OH）2（C2O4）.H2O with good crystallinity proceeded through three stages. Calcining Ti2O2（OH）2（C2O4）·H2O, anatase （350℃） or mtile （550℃） type TiO2 was obtained, respectively. Element analysis found that the calcined product contained 94.9% TiO2 and 2.5% iron oxide, but only about 1600 ppm dissolvable iron oxide was left, which indicates that oxalic acid was comparatively effective on iron oxide removal from the intermediates. Finally, an improved route was proposed for the upgrading of ilmenite into mtile.

关键词： ilmenite iron removal titanium oxide oxalate potassium hydroxide KOH leaching

Powell dynamic identification of displacement parameters of indeterminate thin-walled curve box based on FCSE theory

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Acta Mechanica Sinica 2011年第3期27卷 452-460页

作者： jian Zhang chu-Wei Zhou jia-Shou Zhuo College of Aerospace Engineering Nanjing University of Aeronautics and Astronautics 210016 Nanjing China College of Mechanics and Material Hohai University 210098 Nanjing China

The FCSE controlling equation of pinned thinwalled curve box was derived and the indeterminate problem of continuous thin-walled curve box with diaphragm was solved based on flexibility theory. With Bayesian statistical theory,dynamic Bayesian error function of displacement parameters of indeterminate curve box was founded. The corresponding formulas of dynamic Bayesian expectation and variance were deduced. Combined with one-dimensional Fibonacci automatic search scheme of optimal step size,the Powell optimization theory was utilized to research the stochastic identification of displacement parameters of indeterminate thin-walled curve box. Then the identification steps were presented in detail and the corresponding calculation procedure was compiled. Through some classic examples,it is obtained that stochastic performances of systematic parameters and systematic responses are simultaneously deliberated in dynamic Bayesian error function. The one-dimensional optimization problem of the optimal step size is solved by adopting Fibonacci search method. And the Powell identification of displacement parameters of indeterminate thin-walled curve box has satisfied numerical stability and convergence,which demonstrates that the presented method and the compiled procedure are correct and *** parameters鈥？iterative processes,the Powell theory is irrelevant with the calculation of finite curve strip element（FCSE） partial differentiation,which proves high computation effciency of the studied method.

关键词： Powell theory - Indeterminate curve box . Displacement parameters - Fibonacci search method.Flexibility theory

低强度抗阻结合血流限制训练12周青年人体成分、肌肉力量及动脉弹性功能

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中国组织工程研究 2025年第12期29卷 2521-2527页

作者：贾月新田赛赛祁晓红张素芹江苏卫生健康职业学院江苏省南京市210000

背景:高强度抗阻训练能有效提高肌肉力量,但动脉硬化风险较高;高强度抗阻训练结合有氧运动可有效降低动脉硬化水平;低强度抗阻结合血流限制训练不需要高负荷力量刺激肌肉,或许是提高肌肉力量、保持动脉弹性的科学训练方法。目的:探讨12... 详细信息

背景:高强度抗阻训练能有效提高肌肉力量,但动脉硬化风险较高;高强度抗阻训练结合有氧运动可有效降低动脉硬化水平;低强度抗阻结合血流限制训练不需要高负荷力量刺激肌肉,或许是提高肌肉力量、保持动脉弹性的科学训练方法。目的:探讨12周的低强度抗阻训练结合血流限制训练对青年人体成分、肌肉力量及动脉弹性功能的影响,为制定个性化训练方案提供理论支撑。方法:随机招募55名大学生并通过抽签的方式随机分为高强度抗阻训练组、高强度抗阻结合有氧运动组及低强度抗阻结合血流限制训练组,分别进行为期12周的高强度抗阻训练、高强度抗阻训练结合有氧运动、低强度抗阻训练结合血流限制训练,训练结束后进行身体成分、肌肉力量及动脉弹性功能测试。结果与结论:12周的训练干预后,高强度抗阻训练组、低强度抗阻结合血流限制训练组的瘦体质量显著增加(P<0.05),3组的最大重复次数(1RM)和膝关节等速肌力均显著增加(P<0.05),高强度抗阻结合有氧运动组、低强度抗阻结合血流限制训练组的动脉弹性功能显著改善(P<0.05)。结果表明:12周的高强度抗阻训练、低强度抗阻训练结合血流限制训练能显著改善身体成分;3种训练方式均能增加肌肉力量;12周的高强度抗阻训练结合有氧运动、低强度抗阻训练结合血流限制训练均能改善动脉弹性功能,且低强度抗阻训练结合血流限制训练的效果优于高强度抗阻训练结合有氧运动。因此,建议将低强度抗阻训练结合血流限制训练作为首选训练方式,以改善动脉弹性,降低动脉硬化的风险。

关键词：高强度抗阻训练有氧运动血流限制训练体成分肌肉力量动脉弹性功能

α-Glucosidase Inhibitory Activities of Lutein and Zeaxanthin Purified from Green Alga Chlorella ellipsoidea

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Journal of Ocean University of China 2018年第4期17卷 983-989页

作者： qi jia KIM Sang Moo CAS Key Laboratory of Microbial Physiological and Metabolic Engineering Institute of MicrobiologyChinese Academy of Sciences Department of Marine Food Science and Technology Gangneung-Wonju National University

α-Glucosidase inhibitors are used therapeutically to treat type-2 diabetes mellitus. Through a bioassay-guided fractionation technique, three carotenoids,(all-E)-lutein,(all-E)-zeaxanthin and(9-Z)-zeaxanthin, were purified from the green alga Chlorella ellipsoidea, in which(all-E)-lutein and(9-Z)-zeaxanthin had potent α-glucosidase inhibitory activity. IC_(50) values of(all-E)-lutein and(9-Z)-zeaxanthin were 70 and 53.5 μmol L^(-1) against Saccharomyces cerevisiae α-glucosidase, respectively, with non-competitive inhibition. In addition, IC_(50) values of(9-Z)-zeaxanthin against Bacillus stearothermophilus and rat-intestinal α-glucosidase were 805.1 and 671.2 μmol L^(-1), respectively. The K_i values of(all-E)-lutein and(9-Z)-zeaxanthin against S. cerevisiae α-glucosidase were 78.1 and 16.5 μmol L^(-1), respectively. Therefore, C. ellipsoidea carotenoids might be utilized as a novel candidate to prevent type-2 diabetes mellitus related disorders in food and medical industry.

关键词： type-2 diabetes mellitus α-glucosidase inhibitor carotenoids Chlorella ellipsoidea

The Nonlinear Singularly Perturbed Nonlocal Reaction Diffusion Systems

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Acta Mathematicae Applicatae Sinica 2008年第4期24卷 553-562页

作者： jia-qi Mo Xiu Chen Department of Mathematics Anhui Normal University Wuhu 241000 China Department of Mathematics and Physics Hefei University Hefei 230601 China

In this paper the singularly perturbed initial boundary value problems for a nonlocal reaction diffusion system are considered. Using the iteration method and the comparison theorem, the existence and asymptotic behav... 详细信息

关键词： Reaction diffusion system singular perturbation initial boundary value problem

Role of the extracellular matrix in COVID-19

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World Journal of Clinical Cases 2023年第1期11卷 73-83页

作者： jia-jia Huang chu-Wen Wang Ying Liu Ying-Ying Zhang Nai-Bin Yang Yu-chun Yu qi jiang qi-Fa Song Guo-qing qian School of Medicine Ningbo UniversityNingbo 315000Zhejiang ProvinceChina Department of Infectious Diseases Ningbo First HospitalNingbo 315000Zhejiang ProvinceChina Department of Endocrinology Ningbo Ninth HospitalNingbo 315000Zhejiang ProvinceChina Department of Digestive Ningbo First HospitalNingbo 315000Zhejiang ProvinceChina Medical Data Center Ningbo First HospitalNingbo 315000Zhejiang ProvinceChina

An outbreak of coronavirus disease 2019(COVID-19)has spread globally,with over 500 million cases and 6 million deaths to ***-19 is associated with a systemic inflammatory response and abnormalities of the extracellular matrix(ECM),which is also involved in inflammatory *** viral infection,ECM proteins are involved in the recruitment of inflammatory cells and interference with target organ metabolism,including in the ***,serum biomarkers of ECM turnover are associated with the severity of COVID-19 and may serve as potential ***,understanding the expression and function of ECM,particularly of the lung,during severe acute respiratory syndrome of the coronavirus 2 infection would provide valuable insights into the mechanisms of COVID-19 *** this review,we summarize the current findings on ECM,such as hyaluronic acid,matrix metalloproteinases,and collagen,which are linked to the severity and inflammation of *** drugs targeting the extracellular surface have been *** the future,these ECM findings could provide novel perspectives on the pathogenesis and treatment of COVID-19.

关键词： COVID-19 SARS-CoV-2 Extracellular Matrix Inflammation

Challenges in Treatment of Primary Sjogren’s Syndrome and Opportunities for Chinese Medicine

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Chinese Journal of Integrative Medicine 2020年第7期26卷 483-485页

作者： HOU jia-qi XUE Luan Department of Rheumatology and Immunology Yueyang Hospital of Integrated Traditional Chinese and Western MedicineShanghai University of Traditional Chinese MedicineShanghai(200437)China

Primary Sjogren’s syndrome is a chronic autoimmune disease that can lead to systemic *** present,immunomodulatory agents have not shown good efocacy,many patients in China seek Chinese medicine *** medicine can comprehensively improve the symptoms of patients through Chinese pattern diagnosis and individualized *** researches are providing scientioc bases for the therapeutic effect of Chinese *** Chinese medicine treatment can be integrated into the conventional management of primary Sjogren’s syndrome.

关键词： primary Sjogren's syndrome immunomodulatory agents Chinese medicine

Genetic association of urokinase-type plasminogen activator gene rs2227564 site polymorphism with sporadic Alzheimer's disease in the Han Chinese population

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Neural Regeneration Research 2012年第30期7卷 2377-2383页

作者： Xuelian Ji Longfei jia jianping jia Li qi Department of Neurology Inner Mongolia People's Hospital Huhhot 010017 Inner Mongolia Autonomous Region China Department of Neurology Xuanwu Hospital Capital Medical University Beijing 100053 China Inner Mongolia Corps Hospital Chinese People's Armed Police Forces Huhhot 010040 Inner Mongolia Autonomous Region China

A missense C/T polymorphism in exon 6 （the NCBI rslD is rs2227564） of the urokinase-type plasminogen activator gene has been identified as a possible hot spot for Alzheimer＇s disease risk. The present study analyzed urokinase-type plasminogen gene polymorphisms of rs2227564 with sporadic Alzheimer＇s disease by PCR-restriction fragment length polymorphism. Results showed that CC, CT and TT genotype distribution frequencies had significant differences between sporadic Aizheimer＇s disease patients and healthy controls, in-depth analysis of the association between urokinase-type plasminogen gene rs2227564 polymorphisms and sporadic Alzheimer＇s disease indicated that people with the C-positive genotype CC ＋ CT were at a higher risk for developing sporadic Alzheimer＇s disease. These results support the contribution of the polymorphisms of rs2227564 in the urokinase-type plasminogen gene to the pathogenesis of sporadicAIzheimer＇s disease in the Han Chinese population.

关键词： Alzheimer's disease urokinase plasminogen activator polymorphism genetic testing Han Chinesepopulation neural regeneration