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Acta Metallurgica Sinica(English Letters) 2017年第11期30卷 1080-1088页

作者： Jing Han jia-peng sun Ying Han Huan Liu School of Mechanical and Electrical Engineering China University of Mining and Technology College of Mechanics and Materials Hohai University Key Laboratory of Advanced Structural Materials Ministry of EducationChangchun University of Technology

To develop a fundamental understanding of the flow behavior and optimal hot workability parameters of this material, the hot workability and deformation mechanisms of the as-cast 21Cr EDSS were studied using processing map technology combined with microstructure analysis and isothermal hot compression over the temperature range of 1000-1150 ℃ and strain rate range of 0.01-10 s-1. The processing maps and constitutive equation of peak stress were developed based on Prasad＇s and Murty＇s criteria. The results show that the processing maps exhibit a stable domain at 1000-1150 ℃ and 0.01-1 s-1. The instability domain is exhibited at high strain rates （≥1 s-l）. This implies that Murty＇s criterion can predict the unstable domain with high reliability. The detailed deformation mechanisms are also studied by microstructure observation, showing that the flow localization and microcracking are responsible for the flow instability.

关键词： Duplex stainless steel Constitutive relationship Processing map Hot deformation behavior

Microstructure and Mechanical Properties of Mg–RE–TM Cast Alloys Containing Long Period Stacking Ordered Phases: A Review

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Acta Metallurgica Sinica(English Letters) 2019年第3期32卷 269-285页

作者： Huan Liu He Huang jia-peng sun Ce Wang Jing Bai Ai-Bin Ma Xian-Hua Chen College of Mechanics and Materials Hohai University College of Materials Science and Engineering Southeast University National Engineering Research Center for Magnesium Alloys (CCMg) Chongqing University

Casting magnesium alloys hold the greatest share of magnesium application products due to their short processing period, low cost and near net shape forming. Compared with conventional commercial magnesium alloys or other Mg–RE-based alloys, the novel Mg–RE–TM cast alloys with long period stacking ordered(LPSO) phases usually possess a higher strength and are promising candidates for aluminum alloy applications. Up to now, two ways: alloying design and casting process control(including subsequent heat treatments), have been predominantly employed to further improve the mechanical properties of these alloys. Alloying with other elements or ceramic particles could alter the solidifi cation pattern of alloys, change the morphology of LPSO phases and refi ne the microstructures. Diff erent casting techniques(conventional casting, rapidly solidifi cation, directional solidifi cation, etc.) introduce various microstructure characteristics, such as dendritic structure, nanocrystalline, metastable phase, anisotropy. Further heat treatments could activate the transformation of various LPSO structures and precipitation of diverse precipitates. All these evolutions exert great impacts on the mechanical properties of the LPSO-containing alloys. However, the underlying mechanisms still remain a subject of debate. Therefore, this review mainly provides the state of the art of the casting magnesium alloys research and the accompanying challenges and summarizes some topics that merit future investigation for developing high-performance Mg–RE–TM cast alloys.

关键词： Magnesium alloys Long period stacking ordered phase Casting Heat treatment Phase transformations Mechanical properties

Comparison of Clinical Outcome of Autograft and AIIograft Reconstruction for Anterior Cruciate Ligament Tears

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Chinese Medical Journal 2015年第23期128卷 3163-3166页

作者： Yu-Hua jia peng-Fei sun Department of Orthopedics Qilu Hospital of Shandong University Jinan Shandong 250012 China

Background： Hamstring （HS） autograft and bone-patellar tendon-bone allograft are the most common choice for reconstruction of anterior cruciate ligament （ACL）. There was a little report about the clinical outcome and difference of arthroscopic ACL reconstruction using allograft and autograft. This study aimed to compare the clinical outcome of autograft and allograft reconstruction for ACL tears. Methods： A total of 106 patients who underwent surgery because of ACL tear were included in this study. The patients were randomly divided into two groups, including 53 patients in each group. The patients in group I underwent standard ACL reconstruction with HS tendon autografts, while others in group II underwent reconstruction with bone-patellar tendon-bone allograft. All the patients were followed up and analyzed; the mean follow-up was 81 months （range： 28-86 months）. Clinical outcomes were evaluated using the International Knee Documentation Committee （IKDC）, Lysholm scores, physical instability tests, and patient satisfaction questionnaires. The complication rates of both groups were compared. Tibial and femoral tunnel widening were assessed using lateral and anteroposterior radiographs. Results： At the end of follow-up, no significant differences were found between the groups in terms of IKDC, Lysholm scores, physical instability tests, patient satisfaction questionnaires, and incidences of arthrofibrosis. Tibial and femoral tunnel widening was less in the HS tendon autografts. This difference was more significant on the tibial side. Conclusions： In the repair of ACL tears, allograft reconstruction is as effective as the autograft reconstruction, but the allograft can lead to more tunnel widening evidently in the tibial tunnel, particularly.

关键词： Allograft Anterior Cruciate Ligament Autograft Reconstruction

In situ polymerization of poly(3,4-ethylenedioxythiophene)protective layer towards stable zinc anode

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Nano Research 2025年第1期18卷 382-394页

作者： Debin Luo peng Zhou Xiaowei Lv Panpan sun Xiaohua sun Hewei Zhao College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion MaterialsChina Three Gorges UniversityYichang 443002China Hubei Three Gorges Laboratory Yichang 443007China School of Chemistry Beihang UniversityBeijing 100191China

Aqueous zinc-ion devices are considered promising candidates for energy storage due to their high safety,low cost and relatively high energy ***,the dendrite growth,hydrogen evolution reaction(HER)and corrosion of the zinc anode significantly limit the development of Zn-ion ***,an inexpensive poly(3,4-ethylenedioxythiophene)(PEDOT)protective layer was constructed in situ on the Zn surface using electropolymerization to suppress dendrite growth and side reactions,thereby enhancing the reversibility of *** and theoretical calculations revealed that this hydrophilic protective layer promotes the desolvation process of hydrated Zn^(2+)and facilitates the transport of zinc ions,thus improving the thermodynamic and kinetic properties of Zn^(2+)deposition and inhibiting interfacial side ***,the optimized PEDOT@Zn symmetric battery exhibited a cycling stability exceeding 1250 h at 0.5 mA·cm^(-2)and 0.25 mAh·cm^(-2),with a significantly reduced overpotential(from 91.8 to 35 mV).With the assistance of the PEDOT protective layer,the PEDOT@Zn//Cu battery maintained approximately 99.5%Coulombic efficiency after 450 ***-situ scanning electron microscopy(SEM)and in situ optical microscopy characterizations further confirmed that the PEDOT protective layer can effectively suppress the growth of zinc ***,the Zn-ion capacitors assembled by the PEDOT@Zn and activated carbon also demonstrated outstanding cycling stability.

关键词： zinc-ion devices zinc anode poly(3 4-ethylenedioxythiophene)(PEDOT) dendrite desolvation process

现代汉语不及物动词带旁格宾语结构的句法生成——以包含库藏差异的句法制图理论为基础

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安徽电气工程职业技术学院学报 2017年第2期22卷 48-55页

作者：彭家法孙超安徽大学文学院安徽合肥230039

文章以语料调查为基础,考察各类不及物动词带旁格宾语结构的句法特点;同时,运用"包含库藏差异的句法制图"理论对该结构的生成机制进行相关解释;研究显示,汉语不及物动词带旁格宾语的句法结构中具有词根动词的移位现象,汉语动词库藏具有... 详细信息

文章以语料调查为基础,考察各类不及物动词带旁格宾语结构的句法特点;同时,运用"包含库藏差异的句法制图"理论对该结构的生成机制进行相关解释;研究显示,汉语不及物动词带旁格宾语的句法结构中具有词根动词的移位现象,汉语动词库藏具有轻动词和词根分离特点,相关轻动词具有隐性特征;不同语言既有普遍性又有差异性。

关键词：句法结构制图不及物动词带旁格宾语结构库藏

RGS4 promotes the progression of gastric cancer through the focal adhesion kinase/phosphatidyl-inositol-3-kinase/protein kinase B pathway and epithelial-mesenchymal transition

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World Journal of Gastroenterology 2025年第2期31卷 113-127页

作者： peng-Yu Chen Pei-Yao Wang Bang Liu Yang-Pu jia Zhao-Xiong Zhang Xin Liu Dao-Han Wang Yong-jia Yan Wei-Hua Fu Feng Zhu Department of General Surgery Tianjin Medical University General HospitalTianjin Medical UniversityTianjin 300052China Department of General Surgery Jincheng People’s HospitalJincheng 048000Shanxi ProvinceChina

BACKGROUND Regulator of G protein signaling(RGS)proteins participate in tumor formation and metastasis by acting on theα-subunit of heterotrimeric G *** speci-fic effect of RGS,particularly RGS4,on the progression of gastric cancer(GC)is not yet *** To explore the role and underlying mechanisms of action of RGS4 in GC *** The prognostic significance of RGS4 in GC was analyzed using bioinformatics based public databases and verified by immunohistochemistry and quantitative polymerase chain reaction in 90 patients with *** assays were employed to assess the carcinogenic impact of RGS4,and the mechanism of its possible influence was detected by western blot analysis.A nude mouse xenograft model was established to study the effects of RGS4 on GC growth in *** RGS4 was highly expressed in GC tissues compared with matched adjacent normal *** RGS4 expression was correlated with increased tumor-node-metastasis stage,increased tumor grade as well as poorer overall survival in patients with *** experiments demonstrated that RGS4 knockdown suppressed GC cell proliferation,migration and ***,xenograft experiments confirmed that RGS4 silencing significantly inhibited tumor ***,RGS4 knockdown resulted in reduced phosphorylation levels of focal adhesion kinase,phosphatidyl-inositol-3-kinase,and protein kinase B,decreased vimentin and N-cadherin,and elevated *** High RGS4 expression in GC indicates a worse prognosis and RGS4 is a prognostic ***4 influences tumor progression via the focal adhesion kinase/phosphatidyl-inositol-3-kinase/protein kinase B pathway and epithelial-mesenchymal transition.

关键词： Gastric cancer Prognosis Regulator of G protein signaling 4 Focal adhesion kinase Epithelial-mesenchymal transition

Precipitation behavior of 14H LPSO structure in single 18R phase Mg-Y-Zn alloy during annealing at 773K

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Transactions of Nonferrous Metals Society of China 2017年第1期27卷 63-72页

作者：刘欢严凯晏井利薛烽孙甲鹏江静华马爱斌河海大学力学与材料学院南京211100 河海大学海洋与近海工程研究院南通226300 扬州大学机械工程学院扬州225009 东南大学材料科学与工程学院南京211189

The microstructural evolution of a 18R single phase （S 18） alloy during annealing at 773 K for 100 h was investigated in order to reveal the formation mechanism of 14H phase. The results showed that the as-cast S 18 alloy was composed of 18R phase （its volume fraction exceeds 93%）, W particles and α-Mg phase. The 18R phase in S18 alloy was thermally stable and was not transformed into 14H long period stacking ordered （LPSO） phase during annealing. However, 14H lamellas formed within tiny α-Mg slices, and their average size and volume fraction increased with prolonging annealing time. Moreover, the 14H phase is nucleated within α-Mg independently on the basis of basal stacking faults （SFs）. The broadening growth of 14H lamellas is an interface-controlled process which involves ledges on basal planes, while the lengthening growth is a diffusion-controlled process and is associated with diffusion of solute atoms. The formation mechanism of 14H phase in this alloy could be explained as α-Mg＇→α-Mg＋14H.

关键词： Mg-Y-Zn alloy 18R LPSO phase 14H LPSO phase high-temperature annealing microstructure evolution

Peripheral mitochondrial DNA as a neuroinflammatory biomarker for major depressive disorder

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Neural Regeneration Research 2025年第6期20卷 1541-1554页

作者： Jinmei Ye Cong Duan jiaxin Han Jinrong Chen Ning sun Yuan Li Tifei Yuan Daihui peng Division of Mood Disorder Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Psychiatry First Hospital of Shanxi Medical UniversityTaiyuanShanxi ProvinceChina Shanghai Key Laboratory of Psychotic Disorders Brain Health InstituteNational Center for Mental DisordersShanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Co-Innovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina

In the pathogenesis of major depressive disorder, chronic stress-related neuroinflammation hinders favorable prognosis and antidepressant response. Mitochondrial DNA may be an inflammatory trigger, after its release from stress-induced dysfunctional central nervous system mitochondria into peripheral circulation. This evidence supports the potential use of peripheral mitochondrial DNA as a neuroinflammatory biomarker for the diagnosis and treatment of major depressive disorder. Herein, we critically review the neuroinflammation theory in major depressive disorder, providing compelling evidence that mitochondrial DNA release acts as a critical biological substrate, and that it constitutes the neuroinflammatory disease pathway. After its release, mitochondrial DNA can be carried in the exosomes and transported to extracellular spaces in the central nervous system and peripheral circulation. Detectable exosomes render encaged mitochondrial DNA relatively stable. This mitochondrial DNA in peripheral circulation can thus be directly detected in clinical practice. These characteristics illustrate the potential for mitochondrial DNA to serve as an innovative clinical biomarker and molecular treatment target for major depressive disorder. This review also highlights the future potential value of clinical applications combining mitochondrial DNA with a panel of other biomarkers, to improve diagnostic precision in major depressive disorder.

关键词： biomarker cytokine exosomes inflammasome major depressive disorder microglia mitochondrial DNA mitochondrial dysfunction neuroinflammation Toll-like receptor

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‘禅寺丸’大小孢子发生与雌雄配子体发育

中国农业大学学报 2016年第10期21卷 44-50页

作者：李加茹孙鹏韩卫娟张嘉嘉杜改改傅建敏李芳东国家林业局泡桐研究开发中心郑州450003 中国林业科学研究院经济林研究开发中心郑州450003

为探究禅寺丸大小孢子发生及雌雄配子体发育过程,并观察是否存在花粉及胚囊败育现象,采用常规石蜡切片法对其大、小孢子发生和雌、雄配子体发育的过程进行观察。结果表明:禅寺丸花药四室,花药壁由表皮、药室内壁、中层和腺质绒毡层组成... 详细信息

为探究禅寺丸大小孢子发生及雌雄配子体发育过程,并观察是否存在花粉及胚囊败育现象,采用常规石蜡切片法对其大、小孢子发生和雌、雄配子体发育的过程进行观察。结果表明:禅寺丸花药四室,花药壁由表皮、药室内壁、中层和腺质绒毡层组成;小孢子母细胞减数分裂为同时型,四分体的排列方式为四面体型;成熟花粉粒为2-细胞型,有3个萌发孔;不同药室间及同一药室内的小孢子母细胞减数分裂不同步,且有巨大花粉(未减数花粉)的产生。子房8室,中轴胎座,胚珠倒生,双珠被,薄珠心和单孢原细胞;大孢子四分体直线排列,功能大孢子位于合点端,蓼型胚囊。禅寺丸花粉和胚囊发育过程多数正常,不仅可作为授粉树种,也可作为优良的杂交母本。

关键词：柿小孢子发生雄配子体大孢子发生雌配子体

Porous Organic Cage‑Based Quasi‑Solid‑State Electrolyte with Cavity‑Induced Anion‑Trapping Effect for Long‑Life Lithium Metal Batteries

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Nano-Micro Letters 2025年第2期17卷 376-386页

作者： Wei-Min Qin Zhongliang Li Wen‑Xia Su jia‑Min Hu Hanqin Zou Zhixuan Wu Zhiqin Ruan Yue‑peng Cai Kang Li Qifeng Zheng School of Chemistry South China Normal UniversityGuangzhou 510006People’s Republic of China Key Laboratory of Functional Metal‑Organic Compounds of Hunan Province College of Chemistry and Material ScienceHengyang Normal UniversityHengyang 421008People’s Republic of China Guangzhou Key Laboratory of Energy Conversion and Energy Storage Materials Guangzhou 510006People’s Republic of China

Porous organic cages(POCs)with permanent porosity and excellent host–guest property hold great potentials in regulating ion transport behavior,yet their feasibility as solid-state electrolytes has never been testified in a practical ***,we design and fabricate a quasi-solid-state electrolyte(QSSE)based on a POC to enable the stable operation of Li-metal batteries(LMBs).Benefiting from the ordered channels and cavity-induced anion-trapping effect of POC,the resulting POC-based QSSE exhibits a high Li+transference number of 0.67 and a high ionic conductivity of 1.25×10^(−4) S cm^(−1) with a low activation energy of 0.17 *** allow for homogeneous Li deposition and highly reversible Li plating/stripping for over 2000 *** a proof of concept,the LMB assembled with POC-based QSSE demonstrates extremely stable cycling performance with 85%capacity retention after 1000 ***,our work demonstrates the practical applicability of POC as SSEs for LMBs and could be extended to other energy-storage systems,such as Na and K batteries.

关键词： Porous organic cage Cavity-induced anion-trapping Quasi-solid-state electrolyte Homogeneous Li+flux Lithium metal battery