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Burden of mental disorders and risk factors in the Western Pacific region from 1990 to 2021

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World Journal of Psychiatry 2025年第1期15卷 93-105页

作者： Ya-Xin Xu Xiao-Xuan niu Wen-Chang jia Jing Wen Xue-Lin Cheng Yan Han Ming-Hui Peng Jing Zhou Yao Liu Sun-Fang jiang Xiao-Pan Li Department of Health Management Centre Zhongshan HospitalFudan UniversityShanghai 200030China Department of General Practice Zhongshan HospitalFudan UniversityShanghai 200030China Department of Nutrition Zhongshan HospitalFudan UniversityShanghai 200032China School of Public Health Fudan UniversityShanghai 200032China

BACKGROUND The burden of mental disorders(MD)in the Western Pacific Region(WPR)re-mains a critical public health concern,with substantial variations across demogra-phics and *** To analyze the burden of MD in the WPR from 1990 to 2021,along with associated risk factors,to reveal changing trends and emerging *** We used data from the Global Burden of Disease 2021,analyzing prevalence,incidence,and disability-adjusted life years(DALYs)of MD from 1990 to *** methods included age-standardisation and uncertainty analysis to address variations in population structure and data *** Between 1990 and 2021,the prevalence of MD rose from 174.40 million cases[95%uncertainty interval(UI):160.17-189.84]to 234.90 million cases(95%UI:219.04-252.50),with corresponding DALYs increasing from 22.8 million(95%UI:17.22-28.79)to 32.07 million(95%UI:24.50-40.68).During this period,the burden of MD shifted towards older age *** and anxiety disorders were predominant,with females showing higher DALYs for depressive and anxiety disorders,and males more affected by conduct disorders,attention-deficit hyperactivity disorder,and autism spectrum ***,New Zealand,and Malaysia reported the highest burdens,whereas Vietnam,China,and Brunei Darussalam reported the ***,childhood sexual abuse and bullying,and intimate partner violence emerged as significant risk *** This study highlights the significant burden of MD in the WPR,with variations by age,gender,and *** coronavirus disease 2019 pandemic has exacerbated the situation,emphasizing the need for a coordinated response.

关键词： Mental disorders Western pacific region Global Burden of Disease Risk factors Disability-adjusted life years

Origin of hardening in spectra of cosmic ray nuclei at a few hundred GeV using AMS-02 data

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Chinese Physics C 2021年第4期45卷 25-32页

作者： jia-Shu niu Institute of Theoretical Physics Shanxi UniversityTaiyuan 030006China State Key Laboratory of Quantum Optics and Quantum Optics Devices Shanxi UniversityTaiyuan 030006China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

Many experiments have confirmed spectral hardening at a few hundred GeV in the spectra of cosmic ray(CR)*** different origins have been proposed:primary source acceleration,propagation,and the superposition of different kinds of *** this work,a broken power law has been employed to fit each of the spectra of cosmic ray nuclei from AMS-02 directly,for rigidities greater than 45 *** fitting results of the break rigidity and the spectral index differences less than and greater than the break rigidity show complicated relationships among different nuclear species,which cannot be reproduced naturally by a simple primary source scenario or a propagation ***,with a natural and simple assumption,the superposition of different kinds of sources could have the potential to explain the fitting results *** of CR nuclei from a single future experiment,such as DAMPE,will provide us the opportunity to do cross checks and reveal the properties of the different kinds of sources.

关键词： cosmic ray propagation origin of cosmic ray cosmic ray composition and energy spectrum

On the Mixed Pólya–Szegö Principle

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Acta Mathematica Sinica,English Series 2021年第5期37卷 753-767页

作者： niu Fa FANG jia Zu ZHOU Chern Institute of Mathematics Nankai UniversityTianjin 300071P.R.China School of Mathematics and Statistics Southwest UniversityChongqing 400715P.R.China College of Science Wuhan University of Science and TechnologyWuhan 430081P.R.China

In this paper,the mixed Pólya-Szegöprinciple is *** the mixed Pólya-Szegöprinciple,the mixed Morrey-Sobolev inequality and some new analytic inequalities are obtained.

关键词： Pólya–Szegöprinciple mixed Pólya–Szegöprinciple Sobolev inequality spherically symmetric rearrangement

Efficient Mesh Updating Scheme for the ALE Corotational Formulation of an Arbitrarily Curved Beam

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Acta Mechanica Solida Sinica 2023年第5期36卷 647-657页

作者： Lanfeng Deng mu-Qing niu Yimin Fan Li-Qun Chen Department of Mechanics School of ScienceHarbin Institute of TechnologyShenzhen 518055China

This paper presents an efficient mesh updating scheme(muS)for the arbitrary Lagrangian-Eulerian(ALE)formulation of an arbitrarily curved beam based on the corotational *** discretizing the beam using both Lagrangian elements and ALE elements,the proposed muS can take full advantage of the simple expression form of the Lagrangian formulation and the accurate moving-load description of the ALE *** deleting-node and adding-node procedures of the muS can avoid the negative influence of the variation of the ALE element length on the element accuracy and stiffness matrix *** contrast to the adding-node procedure for Lagrangian elements,interpolation cannot be used *** a Lagrangian node in an ALE element is investigated,and the displacement,velocity,and acceleration of the newly added node are evaluated accurately based on the corotational *** examples are investigated to verify the validity,computational accuracy and computational efficiency of the proposed muS by comparing the results of the muS with those from literature that utilized traditional ALE *** examples show that the proposed muS has significant advantages in terms of computational time and computer memory.

关键词： Corotational method Arbitrary Lagrangian–Eulerian formulation Geometric nonlinearity Moving loads Flexible beams

Molecular Cloning and Tissue-specific Expression of Cu/Zn and Mn-superoxide Dismutase in the Three-keeled Pond Turtle, Chinemys reevesii

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Asian Herpetological Research 2013年第2期4卷 79-89页

作者： Xiaojing jia Cuijuan niu Ministry of Education Key Laboratory of Biodiversity Science and Ecological Engineering College of Life SciencesBeijing Normal University

Both copper/zinc superoxide dismutase （SOD; Cu/Zn-SOD, SOD1） cDNA and manganese SOD （Mn-SOD, SOD2） cDNA were cloned for the first time from the three-keeled pond turtle, Chinemys reevesii, using RT-PCR and RACE methods in this work. The SOD1 cDNA was 749 bp long and consisted of a 32-bp 5＇-untranslated region （UTR）, a 249-bp 3＇-UTR, and a 468-bp open reading frame （ORF） encoding a 155-amino-acid protein with 16.0 kDa predicted molecular mass and 5.95 theoretical isoelectric point （p/）. The SOD2 cDNA was 1687 bp long and comprised 94-bp of 5＇-UTR, 912-bp 3＇-UTR and 681-bp ORF encoding a 226-amino-acid protein with 25.0 kDa predicted molecular mass and 8.83 pI. The deduced amino acid sequence of SOD1 showed relatively high similarity （77.4%-87.1%） and identity （65.4%-74.4%） with the published sequences of SOD1 from other vertebrate species, whereas SOD2 protein shared slightly higher similarity （83.6%-95.6%） and identity （76.1%-88.9%） with other reported vertebrates SOD2s. Phylogenetic analysis revealed that the C. reevesii SOD1 and SOD2 were separately clustered together, and were highly conserved during evolution. Both SOD mRNA expression was detected widely in the brain, liver, muscle, kidney, gut, spleen, lung and heart at variable levels. The highest expression of the two SODs was observed in muscle, and followed in brain, liver, kidney, gut and heart, whereas low transcriptional levels were found in spleen and lung. Meanwhile, high activity of SOD 1 was kept in brain, liver, muscle, kidney and heart, and followed in gut, spleen and lung. The activities of SOD2 in brain, liver, muscle, kidney, gut and heart were significantly higher than those in spleen and lung.

关键词： Chinemys reevesii SOD 1 SOD2 cDNA cloning mRNA expression

Unique Continuation Properties Operators with for Generalized Baouendi-Grushin Singular Weights

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Acta Mathematica Sinica,English Series 2011年第8期27卷 1637-1644页

作者： jia Lin WANG Peng Cheng niu ZDepartment of Applied Mathematics Northwestern Polytechnical University Xi'an 710072 P. R. China Key Laboratory of Numerical Simulation Technology of jiangxi Province Gannan Normal University Ganzhou 341000 P. R. China

In this paper, properties of the spherical functions and Hardy-Sobolev inequalities of generalized Baouendi-Grushin vector fields are established, and then some unique continuation results for generalized Baouendi Gru... 详细信息

关键词： Unique continuation spherical function Hardy-Sobolev inequality generalized Baouendi -Grushin operator

How does conserved dopamine neurotrophic factor protect against and rescue neurodegeneration of PC12 cells？

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Neural Regeneration Research 2017年第7期12卷 1145-1151页

作者： jia-ming Mei Chao-shi niu Shandong University Jinan Shandong Province China Department of Neurosurgery Anhui Provincial Hospital Hefei Anhui Province China

Conserved dopamine neurotrophic factor protects and rescues dopaminergic neurodegeneration induced by 6-hydroxydopamine in vivo,but its potential value in treating Parkinson＇s disease remains ***,we used the proteasome inhibitors lactacystin and MG132 to induce neurodegeneration of PC12 ***,conserved dopamine neurotrophic factor was administrated as a therapeutic factor,both pretreatment and *** results showed that（1）conserved dopamine neurotrophic factor enhanced lactacystin/MG132-induced cell viability and morphology,and attenuated alpha-synuclein accumulation in differentiated PC12 cells.（2）Enzyme linked immunosorbent assay showed up-regulated 26S proteasomal activity in MG132-induced PC12 cells after pre-and posttreatment with conserved dopamine neurotrophic ***,26S proteasome activity was upregulated in lactacystin-induced PC12 cells pretreated with conserved dopamine neurotrophic factor.（3）With regard proteolytic enzymes（specifically,glutamyl peptide hydrolase,chymotrypsin,and trypsin）,glutamyl peptide hydrolase activity was up-regulated in lactacystin/MG132-administered PC12 cells after pre-and posttreatment with conserved dopamine neurotrophic ***,upregulation of chymotrypsin activity was only observed in MG132-administered PC12 cells pretreated with conserved dopamine neurotrophic *** was no change in trypsin *** conclude that conserved dopamine neurotrophic factor develops its neurotrophic effects by modulating proteasomal activities,and thereby protects and rescues PC12 cells against neurodegeneration.

关键词： nerve regeneration conserved dopamine neurotrophic factor Parkinson's disease proteasomal inhibitor 26S proteasome alphasynuclein lactacystin MG-132 glutamyl peptide hydrolase chymotrypsin trypsin neural regeneration

Rotor broken bar fault diagnosis for induction motors based on double PQ transformation

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2007年第8期8卷 1320-1329页

作者： HUANG Jin YANG jia-qiang niu Fa-liang School of Electrical Engineering Zhejiang University Hangzhou 310027 China

A new rotor broken bar fault diagnosis method for induction motors based on the double PQ transformation is pre-sented. By distinguishing the different patterns of the PQ components in the PQ plane,the rotor broken bar fault can be detected. The magnitude of power component directly resulted from rotor fault is used as the fault indicator and the distance between the point of no-load condition and the center of the ellipse as its normalization value. Based on these,the fault severity factor which is completely independent of the inertia and load level is defined. Moreover,a method to reliably discriminate between rotor faults and periodic load fluctuation is presented. Experimental results from a 4 kW induction motor demonstrated the validity of the proposed method.

关键词： PQ transformation Fault diagnosis Load fluctuation Fault severity factor Induction motors

Effect of multilayer graphene/nano-Fe2O3 composite additions on dry sliding wear behavior of titanium matrix composites

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Journal of Iron and Steel Research International 2020年第9期27卷 1117-1126页

作者： Huang Xie Yun-xue Jin mu-ye niu Ji-heng Wang School of Material Science and Engineering Jiangsu University of Science and TechnologyZhenjiang 212003JiangsuChina National Demonstration Center for Experimental Materials Science and Engineering Education(jiangsu University of Science and Technology) Zhenjiang 212003JiangsuChina

The wear tests of titanium matrix composites(TMCs)at the loads of 50,100,120,and 150 N were carried out with an MMW-1 vertical universal friction and wear tester to study the addition of multilayer graphene(MLG)/nano-Fe2O3 composites(0,0.1,0.2,0.3,0.4,and 0.5 g)on the dry sliding wear behavior of *** presented a marked variation in wear loss as a function of the amount of MLG/Fe2O3 addition,and a significant decrease in the friction coefficient was obtained,reducing this parameter up to 50%.With the rise and fall of wear loss,TMCs underwent a transition from severe wear to mild *** phenomena were attributed to the existence of a protective lubricating film,which prevented the surface from coming in direct contact,and the lubricating film was 15-20μm thick and made up of MLG/Fe2O3(1:2)*** structure was speculated to be similar to a rolling wood.

关键词： Titanium matrix composite Graphene Nanomaterial Lubricating film Wear behavior