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Joint effect of pre-operative anemia and perioperative blood transfusion on outcomes of colon-cancer patients undergoing colectomy

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Gastroenterology Report 2020年第2期8卷 151-157,I0003页

作者： Zheng Liu jia-jun luo Kevin Y.Pei Sajid A.Khan Xiao-Xu Wang Zhi-Xun Zhao Ming Yang Caroline H.Johnson Xi-Shan Wang Yawei Zhang Department of Colorectal Surgery National Cancer Center/National Clinical Research Center for Cancer/Cancer HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina Department of Surgery Yale School of MedicineNew HavenCTUSA Department of Surgery School of MedicineTexas Tech University Health Sciences CenterLubbockTXUSA Department of Environmental Health Sciences Yale School of Public HealthNew HavenCTUSA

Background:Both pre-operative anemia and perioperative(intra-and/or post-operative)blood transfusion have been reported to increase post-operative complications in patients with colon cancer undergoing ***,their joint effect has not been *** purpose of this study was to evaluate the joint effect of pre-operative anemia and perioperative blood transfusion on the post-operative outcome of colon-cancer patients after ***:We identified patients from the American College of Surgeons National Surgical Quality Improvement Program(NSQIP)database 2006–2016 who underwent colectomy for colon *** logistic regression analysis was employed to assess the independent and joint effects of anemia and blood transfusion on patient ***:A total of 35,863 patients—18,936(52.8%)with left-side colon cancer(LCC)and 16,927(47.2%)with right-side colon cancer(RCC)—were *** patients were more likely to have mild anemia(62.7%)and severe anemia(2.9%)than LCC patients(40.2%mild anemia and 1.4%severe anemia).A total of 2,661(7.4%)of all patients(1,079[5.7%]with LCC and 1,582[9.3%]with RCC)received a perioperative blood ***,the occurrence rates of complications were comparable between LCC and RCC patients(odds ratio[OR]=1.01;95%confidence interval[CI]=0.95–1.07;P=0.750).There were significant joint effects of anemia and transfusion on complications and the 30-day death rate(P for interaction:0.010).Patients without anemia who received a transfusion had a higher risk of any complications(LCC,OR=3.51;95%CI=2.55–4.85;P<0.001;RCC,OR=3.74;95%CI=2.50–5.59;P<0.001),minor complications(LCC,OR=2.54;95%CI=1.63–3.97;P<0.001;RCC,OR=2.27;95%CI=1.24–4.15;P=0.008),and major complications(LCC,OR=5.31;95%CI=3.68–7.64;P<0.001;RCC,OR=5.64;95%CI=3.61–8.79;P<0.001),and had an increased 30-day death rate(LCC,OR=6.97;95%CI=3.07–15.80;P<0.001;RCC,OR=4.91;95%CI=1.88–12.85;P=0.001)than patients without anemia who did not receive a

关键词： colon cancer colectomy anemia blood transfusion

Revolutionizing breast cancer detection:Advances in fluorescent probe technology

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Nano Research 2025年第1期18卷 653-674页

作者： Qian Gao Lin Tang jun Zhan Yiyuan Xue Feng luo State Key Laboratory of Oral Diseases&National Center for Stomatology&National Clinical Research Center for Oral Diseases West China Hospital of StomatologySichuan UniversityChengdu 610041China Emergency Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China Department of Obstetrics and Gynecology West China Second University HospitalSichuan UniversityChengdu 610041China Department of Prosthodontics West China School of StomatologySichuan UniversityChengdu 610041China

With the increasing incidence of breast cancer globally,there is an urgent demand for enhanced diagnostic and therapeutic *** comprehensive review explores advancements in fluorescent probe technology for breast cancer imaging and early *** probes offer unparalleled sensitivity and specificity in detecting cancer biomarkers,enabling early diagnosis and delineation of tumor margins during *** categorize these probes into molecular,nano,ratiometric,the second near-infrared window(NIR-II),and multifunctional varieties,each with unique capabilities for targeting specific cancer *** review highlights recent innovations in probe design,emphasizing their applications in pathogenesis studies,drug development,precision medicine,and fluorescence-guided *** their promising clinical potential,challenges such as safety,biomarker targeting accuracy,system compatibility,and clinical translation *** these hurdles is crucial for the integration of fluorescent probes into standard cancer care,aiming to improve treatment outcomes and patient quality of life.

关键词： breast cancer fluorescent probes imaging early diagnosis biomarker

Anomalous quality factor evolution of induced transparency in a virtualized coupled-oscillator system

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 148-155页

作者： Yunhan Yang Han jia Tuo Liu Yuzhen Yang jun Yang Key Laboratory of Noise and Vibration Research Institute of Acoustics Chinese Academy of Sciences University of Chinese Academy of Sciences State Key Laboratory of Acoustics Institute of Acoustics Chinese Academy of Sciences

The phenomenon of induced transparency, characterized by a high quality(Q) factor, holds significant importance in the fields of high-precision sensing, energy storage and wave manipulation. Conventional transparency systems are often constrained by the limited experimentally accessible parameter space and the lack of independent control over intrinsic parameters, thereby hindering advanced research on high-Q effects. Here we propose a virtualized coupled-oscillator system that enables reconfigurable induced transparency in the reflection spectrum. By virtually incorporating a pair of coupled oscillators into an individual acoustic meta-atom, we achieve the manipulation of induced transparency in a decoupled, wide-ranging, and elaborate manner. Exploiting the diverse evolutions across the intrinsic parameter space, we show experimentally a counter-intuitive increase in the Q-factor of the transparency window, which is attributed to the enhanced dissipation of the bright ***, a constant group delay at the center frequency is observed accompanying this evolution. Our work demonstrates an intriguing platform as well as a novel strategy to engineer high-Q induced transparency phenomenon, and paves the way towards applications in programmable acoustic sensors, filters and slow-wave devices.

关键词： induced transparency acoustic meta-atom high quality-factor scattering programmable intrinsic parameter

Experimental and simulation studies of single-event transient in partially depleted SOI MOSFET

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Chinese Physics B 2017年第9期26卷 520-525页

作者：闫薇薇高林春李晓静赵发展曾传滨罗家俊韩郑生 Institute of Microelectronics Chinese Academy of SciencesBeijing 100029China Key Laboratory of Silicon Device Technology Chinese Academy of SciencesBeijing 100029China

In this study, we investigate the single-event transient（SET） characteristics of a partially depleted silicon-on-insulator（PDSOI） metal-oxide-semiconductor（MOS） device induced by a pulsed *** measure and analyze the drain transient current at the wafer level. The results indicate that the body-drain junction and its vicinity are more SET sensitive than the other regions in PD-SOI *** use ISE 3D simulation tools to analyze the SET response when different regions of the device are hit. Then, we discuss in detail the characteristics of transient currents and the electrostatic potential distribution change in devices after irradiation. Finally, we analyze the parasitic bipolar junction transistor（p-BJT） effect by performing both a laser test and simulations.

关键词： single-event transient pulsed laser parasitic bipolar junction transistor partially depleted silicon on insulator

Photothermal probiotics delivery of photodynamic agents for enhanced immunogenic cell death within hypoxia center of solid tumors

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Nano Research 2025年第1期18卷 642-652页

作者： Wen luo Shiyu Du Yateng jiang Bangshun He jun Tang Jingjing Yang Yujun Song jiangsu Key Laboratory of Artificial Functional Materials State Key Laboratory of Analytical Chemistry for Life ScienceNational Laboratory of Solid State MicrostructuresCollege of Engineering and Applied SciencesNanjing UniversityNanjing 210023China Department of Laboratory Medicine Nanjing First HospitalNanjing Medical UniversityNanjing 210006China Department of Anesthesiology Jinling HospitalMedical School of Nanjing UniversityNanjing 210000China Department of Biochemistry and Molecular Biology School of Medicine&Holistic Integrative MedicineJiangsu Collaborative Innovation Center of Chinese Medicinal Resources IndustrializationNanjing University of Chinese MedicineNanjing 210023China

Resulting from harsh hypoxic environmental conditions,central cells in the core of solid tumors are usually more aggressive and malignant with a less stable ***,therapeutic agents with improved penetration for the activation of immunity in tumor centers exhibit promising potential in ***,polydopamine-coated Escherichia coli Nissle 1917(EcN)bearing chlorin e6(Ce6)-loaded and polyethyleneimine(PEI)-coated hollow manganese dioxide(shorted as EP-ChP)are applied for enhanced immunotherapy in deep *** accumulation in tumor center through hypoxia targeting,manganese dioxide is degradated under the tumor microenvironment with released Ce6 and thus generates reactive oxygen species(ROS)upon 660 nm laser irradiation,which can further lower thermalresistance of cancer cells via HSP90α*** to that,heating induced by polydopamine upon 808 nm laser irradiation can achieve effective tumor *** upon dual laser induces enhanced immunogenic cell death,while bacterial infections in tumor tissues also trigger innate *** bacteria-based approach provides enhanced antitumor immune responses in deep tumors with great potential in the reshaping of immunosuppression tumor microenvironment.

关键词： bacteria phototherapies immunotherapy hypoxia targeting tumor penetration

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基于数据驱动的软件可靠性预测模型

内蒙古师范大学学报（自然科学汉文版） 2018年第1期47卷 49-54页

作者：农嘉罗峻文广西生态工程职业技术学院汽车与信息工程系广西柳州545007

当前以结果驱动为基础的预测方法存在预测收敛性差、准确性差等问题,为此提出基于数据驱动的软件可靠性预测模型.采集软件运行主机与控制服务器的数据,采用数据驱动的模型进行软件异常事件检测,构建软件演化模型;采用自适应持续性信息... 详细信息

当前以结果驱动为基础的预测方法存在预测收敛性差、准确性差等问题,为此提出基于数据驱动的软件可靠性预测模型.采集软件运行主机与控制服务器的数据,采用数据驱动的模型进行软件异常事件检测,构建软件演化模型;采用自适应持续性信息捕获算法进行软件可靠性建模,实现软件可靠性性约束参量的数据驱动,完成软件可靠性预测.仿真结果表明,采用该模型进行软件可靠性预测的准确性较高,预测过程的收敛性较好,从而提高了软件的寿命周期.

关键词：数据驱动软件可靠性预测寿命周期

Continuous high-temperature rapid nanomanufacturing of electrocatalysts

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Nano Research 2025年第1期18卷 225-235页

作者： Xiaoyang Wang Ziyi luo Baihua Cui Ziqi Fu Yanchang Liu Weidi Liu jia Ding jianrong Zeng Yanan ChenWenbin Hu School of Materials Science and Engineering Tianjin UniversityTianjin 300350China Australian Institute for Bioengineering and Nanotechnology The University of QueenslandSt.LuciaBrisbane 4072Australia Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghai 201204China Shanghai Institute of Applied Physics Chinese Academy of SciencesShanghai 201800China

Encapsulating metal nanoparticles in carbon shells(Metal@C)to enhance catalytic activity and stability has been certified ***,most existing methods for preparing Metal@C are complex,time-consuming,and lack of *** this study,a novel method that couples the high-temperature shock(HTS)with ultrasonic spray pyrolysis is reported,which can realize facile and scalable production of various Metal@C through the pyrolysis of glucose and metal chloride *** proposed HTS ultrasonic spray pyrolysis offers several advantages,including compact size,short reaction time(~120 ms),and uniform *** the Ni@C-40 nanocomposite as an example,the ultrasmall Ni nanoparticles(~10 nm)with thin carbon protective shells(~2 nm)are uniformly dispersed in the carbon matrix and applied for oxygen evolution reaction(OER)in alkaline *** Ni@C-40 optimized by tuning the thickness of carbon shell exhibits significantly enhanced OER activity with low overpotential of 242 mV at 10 mA·cm^(-2) and stability,which is attributed to the optimized interactions between Ni nanoparticles and carbon *** method also shows promise for continuous pyrolysis synthesis of various extreme materials at ultra-high temperatures using alternative electric heating materials.

关键词： ultrasonic spray pyrolysis high-temperature shock carbon shell oxygen evolution reaction Metal@C nanocomposite

Primary parenchymal squamous cell carcinoma of the kidney:A case report

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World Journal of Clinical Cases 2025年第4期13卷 34-40页

作者： Zhi-Hui Zheng Bo Shao Chao-Min Xu Ke Wang jia-Zhu Wen Li-Kang luo jia-Cheng Guan Department of Ultrasound The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Radiology Shulan(Quzhou)HospitalQuzhou 324000Zhejiang ProvinceChina Department of Radiology The Second People’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina Department of Pathology The Second people’s Hospital of QuzhouQuzhou 324000Zhejiang ProvinceChina

BACKGROUND Primary squamous cell carcinoma(SCC)of the renal parenchyma is extremely rare,with only nine cases *** SUMMARY This study reports a 51-year-old man with primary SCC of the renal *** patient was admitted with recurrent dull pain and discomfort in the right lumbar region,which had worsened over 2 weeks,accompanied by painful gross *** antigen(SCCA)levels were elevated,and imaging revealed a renal mass with associated *** patient underwent laparoscopic unilateral nephrectomy and lymph node *** pathology confirmed highly differentiated SCC with necrosis in the right renal parenchyma,with negative renal pelvis and *** pathological stage was *** months after surgery,the tumor recurred with involvement of the liver,right psoas major muscle,and inferior vena *** patient refused chemotherapy and succumbed to the disease 6 months postoperatively due to disease *** We report a case of primary SCC of the renal parenchyma,a rare renal *** clinical symptoms,laboratory tests,and imaging findings are nonspecific,making accurate and timely diagnosis *** to the literature,for patients with renal calculi accompanied by a renal mass,elevated serum SCCA levels,and magnetic resonance imaging showing cystic or cystic-solid masses within the kidney with pseudocapsules and heterogeneous mild enhancement,the possibility of this disease should be considered.

关键词： Renal tumor Renal parenchyma Squamous cell carcinoma Renal calculi Computed tomography Case report

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收集烟头制备锂离子电池负极材料

西南师范大学学报（自然科学版） 2018年第5期43卷 147-151页

作者：李尚远曹家军罗键柴雅琴西南大学附属中学重庆400700 西南大学化学化工学院重庆400715

研究了一种新型的垃圾箱来收集废旧烟头,并将收集的烟头通过一步煅烧的方法制得多孔的无定形炭,将其作锂离子电池负极材料.对所得的材料进行X-射线衍射(XRD)、扫描电子显微镜(SEM)、拉曼(Raman)和投射扫描电子显微镜(TEM)表征.结果表明... 详细信息

研究了一种新型的垃圾箱来收集废旧烟头,并将收集的烟头通过一步煅烧的方法制得多孔的无定形炭,将其作锂离子电池负极材料.对所得的材料进行X-射线衍射(XRD)、扫描电子显微镜(SEM)、拉曼(Raman)和投射扫描电子显微镜(TEM)表征.结果表明,该材料在0.5C的电流密度下,在循环100圈后其容量能够保持在240(mA·h)/g,具有实际应用的潜质.该研究有希望解决废弃烟头的回收利用问题.

关键词：废旧烟头烟头收集孔状无定形碳材料锂离子电池