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Association between composite dietary antioxidant index and stroke among individuals with diabetes

World Journal of Diabetes 2024年第8期15卷 1742-1752页

作者： Hong-Qiang Zhang Jie Shi Tong Yue jia-hao weng Xu-Lin Wang hao Wang Xiao-Yu Su Xue-Ying Zheng Si-Hui Luo Yu Ding Chao-Fan Wang Department of Cardiology Centre for Leading Medicine and Advanced Technologies of IHMThe First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Department of Endocrinology Centre for Leading Medicine and Advanced Technologies of IHMThe First Affiliated Hospital of USTCDivision of Life Sciences and MedicineUniversity of Science and Technology of ChinaHefei 230001Anhui ProvinceChina Graduate School Bengbu Medical CollegeBengbu 233030Anhui ProvinceChina Department of Endocrinology and Metabolism The Third Affiliated Hospital of Sun Yat-sen UniversityGuangdong Provincial Key Laboratory of DiabetologyGuangzhou 510630Guangdong ProvinceChina

BACKGROUND Recent research has underscored the potentially protective role of dietary antioxidants against chronic conditions,such as cardiovascular diseases and *** composite dietary antioxidant index(CDAI),which reflects the overall intake of key dietary antioxidants,has been identified as a crucial metric for exploring this *** previous research has shown a negative correlation between CDAI levels and stroke risk in prediabetic individuals,there remains a substantial gap in understanding this association among individuals with diabetes,who are at an inherently greater risk for cerebrovascular *** To investigate the association between CDAI and stroke risk in individuals with *** Using a cross-sectional study design,this investigation analyzed data from the National Health and Nutrition Examination Survey spanning from 2003 to 2018 that included 6735 participants aged over 20 years with *** CDAI was calculated from 24-h dietary recalls to assess intake of key antioxidants:Vitamins A,C,and E;carotenoids;selenium;and *** logistic regression and restricted cubic spline analysis were used to rigorously examine the relationship between CDAI and stroke *** The participant cohort,with an average age of 59.5 years and a slight male majority,reflected the broader demographic characteristics of individuals with *** analysis revealed a strong inverse relationship between CDAI levels and stroke ***,those in the highest quintile of CDAI demonstrated a 43%lower prevalence of stroke compared to those in the lowest quintile,even after adjustments for various *** finding not only highlights the negative association between CDAI and stroke risk but also underscores the significant potential of antioxidant-rich diets in reducing stroke prevalence among patients with *** Our findings suggested that CDAI was inversely associated with stroke prevalence among pa

关键词： Stroke Diabetes Composite dietary antioxidant index National Health and Nutrition Examination Survey Crosssectional study

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A robust implicit high-order discontinuous Galerkin method for solving compressible Navier-Stokes equations on arbitrary grids

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Acta Mechanica Sinica 2024年第8期40卷 96-119页

作者： jia Yan Xiaoquan Yang Peifen weng Shanghai Institute of Applied Mathematics and Mechanics Shanghai Key Laboratory of Mechanics in Energy EngineeringSchool of Mechanics and Engineering ScienceShanghai UniversityShanghai200072China College of Energy and Mechanical Engineering Shanghai University of Electric PowerShanghai200090China

The primary impediments impeding the implementation of high-order methods in simulating viscous flow over complex configurations are robustness and *** challenges impose significant constraints on computational efficiency,particularly in the domain of engineering *** address these concerns,this paper proposes a robust implicit high-order discontinuous Galerkin(DG)method for solving compressible Navier-Stokes(NS)equations on arbitrary *** method achieves a favorable equilibrium between computational stability and *** solve the linear system,an exact Jacobian matrix solving strategy is employed for preconditioning and matrix-vector generation in the generalized minimal residual(GMRES)*** approach mitigates numerical errors in Jacobian solution during implicit calculations and facilitates the implementation of an adaptive Courant-Friedrichs-Lewy(CFL)number increasing strategy,with the aim of improving convergence and *** further enhance the applicability of the proposed method for intricate grid distortions,all simulations are performed in the reference *** practice significantly improves the reversibility of the mass matrix in implicit calculations.A comprehensive analysis of various parameters influencing computational stability and efficiency is conducted,including CFL number,Krylov subspace size,and GMRES convergence *** computed results from a series of numerical test cases demonstrate the promising results achieved by combining the DG method,GMRES solver,exact Jacobian matrix,adaptive CFL number,and reference domain calculations in terms of robustness,convergence,and *** analysis results can serve as a reference for implicit computation in high-order calculations.

关键词： Discontinuous Galerkin method Exact Jacobian matrix GMRES solver Adaptive CFL number Reference domain High-order

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Optimal Assimilation of Microwave Upper-Level Sounding Data in CMA-GFS

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Advances in Atmospheric Sciences 2024年第10期41卷 2043-2060页

作者： Changjiao DONG hao HU Fuzhong weng School of Atmospheric Physics Nanjing University of Information Science and TechnologyNanjing 210044China CMA Earth System Modeling and Prediction Centre(CEMC) China Meteorological AdministrationBeijing 100081China State Key Laboratory of Severe Weather Chinese Academy of Meteorological SciencesBeijing 100081China

Various approaches have been proposed to minimize the upper-level systematic biases in global numerical weather prediction(NWP)models by using satellite upper-air sounding channels as ***,since the China Meteorological Administration Global Forecast System(CMA-GFS)has a model top near 0.1 hPa(60 km),the upper-level temperature bias may exceed 4 K near 1 hPa and further extend to 5 *** this study,channels 12–14 of the Advanced Microwave Sounding Unit A(AMSU-A)onboard five satellites of NOAA and METOP,whose weighting function peaks range from 10 to 2 hPa are all used as anchor observations in *** is shown that the new“Anchor”approach can effectively reduce the biases near the model top and their downward propagation in three-month assimilation *** bias growth rate of simulated upper-level channel observations is reduced to±0.001 K d^(–1),compared to–0.03 K d^(–1)derived from the current dynamic correction *** relatively stable bias significantly improves the upper-level analysis field and leads to better global medium-range forecasts up to 10 days with significant reductions in the temperature and geopotential forecast error above 10 hPa.

关键词： CMA-GFS upper-level model bias anchoring bias correction satellite microwave data assimilation

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Cloud-Type-Dependent 1DVAR Algorithm for Retrieving Hydrometeors and Precipitation in Tropical Cyclone Nanmadol from GMI Data

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Advances in Atmospheric Sciences 2024年第3期41卷 407-419页

作者： Linjun HAN Fuzhong weng hao HU Xiuqing HU School of the Environment China University of Geosciences(Wuhan)Wuhan 430074China Chinese Academy of Meteorological Sciences Beijing 100081China CMA Earth System Modeling and Prediction Centre Beijing 100081China Key Laboratory of Radiometric Calibration and Validation for Environmental Satellites National Satellite Meteorological Center(National Center for Space Weather)of CMABeijing 100081China

Understanding the structure of tropical cyclone(TC)hydrometeors is crucial for detecting the changes in the distribution and intensity of *** this study,the GMI brightness temperature and cloud-dependent 1DVAR algorithm were used to retrieve the hydrometeor profiles and surface rain rate of TC Nanmadol(2022).The Advanced Radiative Transfer Modeling System(ARMS)was used to calculate the Jacobian and degrees of freedom(△DOF)of cloud water,rainwater,and graupel for different channels of GMI in convective *** retrieval results were compared with the Dual-frequency Precipitation Radar(DPR),GMI 2A,and IMERG *** is shown that from all channels of GMI,rain water has the highest△DOF,at *** to the radiance Jacobian to atmospheric state variables,cloud water emission dominates its *** rain water,the emission of channels 1–4 dominates *** with the GMI 2A precipitation product,the 1DVAR precipitation rate has a higher correlation coefficient(0.713)with the IMERG product and can better reflect the location of TC *** the TC eyewall,the highest radar echo top indicates strong *** the melting layer where Ka-band attenuation is strong,the double frequency difference of DPR data reflects the location of the *** DPR drop size distribution(DSD)product shows that there is a significant increase in particle size below the melting layer in the spiral rain ***,the particle size may be one of the main reasons for the smaller rain water below the melting layer retrieved from 1DVAR.

关键词： cloud-dependent 1DVAR hydrometeor precipitation GMI DPR

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Lead-free perovskites-based photonic synaptic devices with zero electric energy consumption

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Science China(Information Sciences) 2024年第6期67卷 433-441页

作者： Dandan hao Di YANG Haixia LIANG jia HUANG Fukai SHAN College of Electronics and Information Qingdao University Key Laboratory of Biofuels Qingdao Institute of Bioenergy and Bioprocess TechnologyChinese Academy of Sciences School of Materials Science and Engineering Tongji University National Key Laboratory of Autonomous Intelligent Unmanned Systems Tongji University

The von Neumann bottleneck is a critical limitation in synaptic devices. Therefore, artificial synaptic devices resembling biological neuromorphic synapses have been developed to overcome the von Neumann bottleneck. However, synaptic devices require voltages, which results in considerable energy consumption. Here, photonic synaptic devices with the vertical structure of indium tin oxide（ITO）/SnO2/Al2O3/CsBi3I10/Au are fabricated, which can work in the self-powered mode owing to the photovoltaic effect endowed by a vertical multilayer structure. Several fundamental synaptic functions, such as excitatory postsynaptic current, paired-pulse facilitation, short-term plasticity（STP）, long-term plasticity（LTP）, pulse-frequency-dependent plasticity, transition of STP to LTP, and the learning experience are emulated. Moreover, Morse-coded external light information is decoded by self-powered photonic synaptic devices. The results indicate that self-powered photonic synaptic devices based on lead-free perovskites exhibit great potential for efficient neuromorphic computing and optical wireless communication.

关键词： photonic synaptic devices lead-free perovskites zero energy consumption synaptic plasticity Morse code

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Vertically aligned montmorillonite aerogel-encapsulated polyethylene glycol with directional heat transfer paths for efficient solar thermal energy harvesting and storage

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International Journal of Minerals,Metallurgy and Materials 2024年第5期31卷 907-916页

作者： Qijing Guo Cong Guo hao Yi Feifei jia Shaoxian Song Key Laboratory of Green Utilization of Critical Non-metallic Mineral Resources Ministry of EducationWuhan University of TechnologyWuhan 430070China School of Resources and Environmental Engineering Wuhan University of TechnologyWuhan 430070China Hubei Key Laboratory of Mineral Resources Processing and Environment Wuhan University of TechnologyWuhan 430070China

The conversion and storage of photothermal energy using phase change materials(PCMs)represent an optimal approach for harnessing clean and sustainable solar ***,we encapsulated polyethylene glycol(PEG)in montmorillonite aerogels(3D-Mt)through vacuum impregnation to prepare 3D-Mt/PEG composite *** used as a support matrix,3D-Mt can effectively prevent PEG leakage and act as a flame-retardant barrier to reduce the flammability of ***,3D-Mt/PEG demonstrates outstanding shape retention,increased thermal energy storage density,and commendable thermal and chemical *** phase transition enthalpy of 3D-Mt/PEG can reach 167.53 J/g and remains stable even after 50 heating-cooling ***,the vertical sheet-like structure of 3D-Mt establishes directional heat transport channels,facilitating efficient phonon *** configuration results in highly anisotropic thermal conductivities that ensure swift thermal responses and efficient heat *** study addresses the shortcomings of PCMs,including the issues of leakage and inadequate flame *** achieves the development and design of 3D-Mt/PEG with ultrahigh strength,superior flame retardancy,and directional heat ***,this work offers a design strategy for the preparation of high-performance composite *** 3D-Mt/PEG with vertically aligned and well-ordered array structure developed in this research shows great potential for thermal management and photothermal conversion applications.

关键词： montmorillonite aerogel polyethylene glycol phase change materials solar thermal energy storage flame retardant

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A Note on B-Subdifferential of Projection Operator on Polyhedral Set

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Journal of the Operations Research Society of China 2024年第3期12卷 837-845页

作者： hao-Yang Liu jia Wu Li-Wei Zhang Institute of Operations Research and Control Theory School of Mathematical SciencesDalian University of TechnologyDalian116024LiaoningChina

This note characterizes the set of Fréchet-differentiable points of the projection operator on a polyhedral set and the B-subdifferential of this projection operator at any point.

关键词： Polyhedral set Projection operator B-subdifferential Strong regularity

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Anderson Acceleration of Gradient Methods with Energy for Optimization Problems

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Communications on Applied Mathematics and Computation 2024年第2期6卷 1299-1318页

作者： Hailiang Liu jia-hao He Xuping Tian Department of Mathematics Iowa State UniversityAmesIAUSA Department of Agricultural and Biosystems Engineering Iowa State UniversityAmesIAUSA

Anderson acceleration(AA)is an extrapolation technique designed to speed up fixed-point *** optimization problems,we propose a novel algorithm by combining the AA with the energy adaptive gradient method(AEGD)[arXiv:2010.05109].The feasibility of our algorithm is ensured in light of the convergence theory for AEGD,though it is not a fixed-point *** provide rigorous convergence rates of AA for gradient descent(GD)by an acceleration factor of the gain at each implementation of *** experimental results show that the proposed AA-AEGD algorithm requires little tuning of hyperparameters and exhibits superior fast convergence.

关键词： Anderson acceleration(AA) Gradient descent(GD) Energy stability

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A real-time calibration method based on time-to-digital converter for accelerator timing system

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Nuclear Science and Techniques 2024年第9期35卷 127-140页

作者： Qi-hao Duan Liang Ge Yan-hao jia Jie-Yu Zhu Wei Zhang Institute of modern physics Chinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China

The high-intensity heavy-ion accelerator facility(HIAF)is a scientific research facility complex composed of multiple cas-cade accelerators of different types,which pose a scheduling problem for devices distributed over a certain range of 2 km,involving over a hundred *** white rabbit,a technology-enhancing Gigabit Ethernet,has shown the capability of scheduling distributed timing devices but still faces the challenge of obtaining real-time synchronization calibration param-eters with high *** study presents a calibration system based on a time-to-digital converter implemented on an ARM-based System-on-Chip(SoC).The system consists of four multi-sample delay lines,a bubble-proof encoder,an edge controller for managing data from different channels,and a highly effective calibration module that benefits from the SoC *** performance was evaluated with an average RMS precision of 5.51 ps by measuring the time intervals from 0 to 24,000 ps with 120,000 data for every *** design presented in this study refines the calibration precision of the HIAF timing *** eliminates the errors caused by manual calibration without efficiency loss and provides data support for fault *** can also be easily tailored or ported to other devices for specific applications and provides more space for developing timing systems for particle accelerators,such as white rabbits on HIAF.

关键词： HIAF White rabbit Calibration system Time-to-digital converter(TDC)

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Development of a cell-permeable adenine-derived probe for capture of nucleotide-binding proteins in living cells

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Chinese Chemical Letters 2024年第3期35卷 243-246页

作者： Lihong Liu Rui Chen Gang Xue Chenzhou hao Weizhi weng Zhengying Pan State Key Laboratory of Chemical Oncogenomics School of Chemical Biology and BiotechnologyPeking University Shenzhen Graduate SchoolShenzhen 518055China

Adenine is an essential building block of genetic material and a range of *** probes containing an adenine moiety have been used in kinase profiling studies in cell *** we report that adenine-derived small-molecule probes with an activated ester reactive group can covalently modify a conserved lysine residue of protein kinases and capture a number of nucleotide-binding proteins within living cells.

关键词： Adenine-derived probe Cell-permeable Lysine residue Protein kinases Nucleotide-binding proteins

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