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Association of stent thrombectomy and conventional treatment with neuroprotection, complications, anxiety, and depression in acute ischemic stroke patients

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World Journal of Psychiatry 2025年第1期15卷 72-82页

作者： Kai-Jie Yang jia-jian huang Cai-Xia Xuan Department of Neurology Qinzhou Second People's HospitalQinzhou 535000Guangxi Zhuang Autonomous RegionChina

BACKGROUND Acute ischemic stroke(AIS)is an abrupt blood flow cessation to a specific brain region within a vascular zone,causing a subsequent decline in neurological *** thrombectomy is a recently established technique for treating *** provides the benefits of being a relatively simple and safe procedure,capable of partially enhancing a patient’s ***,some patients may experience endothelial damage and recurrent thrombosis,with clinical outcomes that are not always ***,the efficacy of this method remains *** To survey the association of stent thrombectomy vs standard treatment with neurological function protection,complications,and short-term prognosis in patients diagnosed with *** This study assigned 90 patients with AIS to the observation and control groups(n=45 patients)from December 2020 to December *** thrombectomy was conducted in the observation group,whereas routine treatment was provided to the control *** study assessed the therapeutic outcomes of two groups,including a comparison of their neurological function,living ability,anxiety and depression status,plaque area,serum inflammatory factors,serum Smur100βprotein,neuron-specific enolase(NSE),homocysteine(Hcy),and vascular endo-thelial ***,the incidence of complications was calculated and analyzed for each *** The total effective rate of treatment was 77.78%and 95.56%in the control and observation groups,*** 8 weeks of treatment,the scores on the National Institutes of Health Stroke Scale,Hamilton Anxiety Scale,and Hamilton Depression Scale decreased remarkably;the Barthel index increased remarkably,with better improvement effects of the scores in the observation group(P<0.05);total cholesterol,triglyceride,C-reactive protein,and plaque area lessened remarkably,with fewer patients in the observation group(P<0.05);S-100βprotein,NSE,and Hcy levels lessened remarkably,with fewer patients in

关键词： Stent thrombectomy Acute ischemic stroke Neurological function Complications Short-term prognosis

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The patterns of surface capillary-gravity short-crested waves with uniform current fields in coastal waters

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Acta Mechanica Sinica 2006年第5期22卷 433-441页

作者： Hu huang jia Fu Shanghai Institute of Applied Mathematics and Mechanics Shanghai University Shanghai 200072 China

A fully three-dimensional surface gravitycapillary short-crested wave system is studied as two progressive wave-trains of equal amplitude and frequency, which are collinear with uniform currents and doubly-periodic in the horizontal plane, are propagating at an angle to each other. The first- and second-order asymptotic analytical solutions of the short-crested wave system are obtained via a perturbation expansion in a small parameter associated with the wave steepness, therefore depicting a series of typical three-dimensional wave patterns involving currents, shallow and deep water, and surface capillary waves, and comparing them with each other.

关键词： Short-crested waves Uniform currents Patterns Surface capillary-gravity waves Finite depth and deep water

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Projective vector fields on Finsler manifolds

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Applied Mathematics(A Journal of Chinese Universities) 2014年第2期29卷 217-229页

作者： TIAN huang-jia Department of Mathematics Zhejiang University

In this paper, we give the equation that characterizes projective vector fields on a Finsler manifold by the local coordinate. Moreover, we obtain a feature of the projective fields on the compact Finsler manifold with non-positive flag curvature and the non-existence of projective vector fields on the compact Finsler manifold with negative flag curvature. Furthermore, we deduce some expectable, but non-trivial relationships between geometric vector fields such as projective, affine, conformal, homothetic and Killing vector fields on a Finsler manifold.

关键词： Finsler manifold projective vector field conformal vector field.

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A hybrid proportional navigation based two-stage impact time control guidance law

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Journal of Systems Engineering and Electronics 2022年第2期33卷 461-473页

作者： huang jia CHANG Sijiang CHEN Shengfu School of Energy and Power Engineering Nanjing University of Science and TechnologyNanjing 210094China The 20th Research Institute of China Electronics Technology Group Corporation Xi’an 710068China

To improve applicability and adaptability of the impact time control guidance(ITCG) in practical engineering, a twostage ITCG law with simple but effective structure is proposed based on the hybrid proportional navigation, namely, the pureproportional-navigation and the *** the case with the impact time error less than zero, the first stage of the guided trajectory is driven by the retro-proportionalnavigation and the second one is driven by the pure-proportionalnavigation. When the impact time error is greater than zero, both of the stages are generated by the pure-proportional-navigation but using different navigation gains. It is demonstrated by twoand three-dimensional numerical simulations that the proposed guidance law at least has comparable results to existing proportional-navigation-based ITCG laws and is shown to be advantageous in certain circumstances in that the proposed guidance law alleviates its dependence on the time-to-go estimation, consumes less control energy, and adapts itself to more boundary conditions and constraints. The results of this research are expected to be supplementary to the current research literature.

关键词： missile guidance law impact time control pure-proportional-navigation retro-proportional-navigation time-to-go estimation

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Fragment Identification and Statistics Method of Hypervelocity Impact SPH Simulation

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Chinese Journal of Aeronautics 2011年第1期24卷 18-24页

作者： ZHANG Xiaotian jia Guanghui huang Hai School of Astronautics Beo'ing University of Aeronautics and Astronautics Beijing 100191 China

A comprehensive treatment to the fragment identification and statistics for the smoothed particle hydrodynamics （SPH） simulation of hypervelocity impact is presented. Based on SPH method, combined with finite element method （FEM）, the computation is performed. The fragments are identified by a new pre- and post-processing algorithm and then converted into a binary graph. The number of fragments and the attached SPH particles are determined by counting the quantity of connected domains on the binary graph. The size, velocity vector and mass of each fragment are calculated by the particles’ summation and weighted average. The dependence of this method on finite element edge length and simulation terminal time is discussed. An example of tungsten rods impacting steel plates is given for calibration. The computation results match experiments well and demonstrate the effectiveness of this method.

关键词： impact simulation smoothed particle hydrodynamics fragment hypervelocity

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Chimeric Monkey Born Alive with a High Contribution of Donor Cells

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Neuroscience Bulletin 2024年第6期40卷 849-851页

作者： jia huang Jun Wu Department of Molecular Biology University of Texas Southwestern Medical CenterDallasTX75390USA Hamon Center for Regenerative Science and Medicine University of Texas Southwestern Medical CenterDallasTX75390USA Cecil H.and Ida Green Center for Reproductive Biology Sciences University of Texas Southwestern Medical CenterDallasTX75390USA

Chimeras,which consist of cells from different individuals or different species,represent an important tool in biological *** in the early twentieth century,studies on chimeras have been focusing on understanding fundamental genetic and cellular developmental *** the advances in genetic engineering and embryonic stem cell(ESC)technology,chimeras have become an important tool for the generation of transgenic animals.

关键词： mechanisms advances developmental

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A TVD SCHEME FOR INCOMPRESSIBLE FLOW COUPLED WITH DIFFERENT TURBULENCE MODLES ON A GROUND-MOUNTED SQUARE-RIB FLOW

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Journal of Hydrodynamics 2007年第6期19卷 743-750页

作者： WANG jia-song huang Zhen School of Mechanical Engineering Shanghai Jiaotong University Shanghai 200240 China

A finite-difference Total Variation Diminishing （TVD） numerical simulation model for coupling the Reynolds Averaged Navier-Stokes （RANS） equations, pressure-relative continuity equation and various k-εturbulence models was developed to solve the incompressible flow based on the pseudo-compressibility method. The hyperbolicity of all these equations was studied and the discretization of the fully coupling equations with all the primal variables and source terms were made in this article. Numerical simulation for modeling the flow around a ground-mounted square rib was implemented and validated by comparing with the published wind tunnel experimental data. It is shown that such a numerical simulation method with a proper turbulence model has a very good accuracy to simulate the flow around a surface-mounted rib. It is concluded that the Renormalization Group （RNG） and Chen-Kim k-εturbulence models have much better ability to predict the characteristics of the vortex structure and flow separation than the standard k-εmodel.

关键词： Total Variation Diminishing (TVD) scheme Reynolds Averaged Navier-Stokes (RANS) turbulence models,square rib pseudo-compressibility method

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Effective exposure of nitrogen heteroatoms in 3D porous graphene framework for oxygen reduction reaction and lithium–sulfur batteries

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Journal of Energy Chemistry 2018年第1期27卷 167-175页

作者： jia-Le Shi Cheng Tang jia-Qi huang Wancheng Zhu Qiang Zhang Beijing Key Laboratory of Green Chemical Reaction Engineering and Technology Department of Chemical EngineeringTsinghua UniversityBeijing 100084China Advanced Research Institute for Multidisciplinary Science Beijing Institute of TechnologyBeijing 100081China Department of Chemical Engineering Qufu Normal UniversityQufu 273165ShandongChina Key Laboratory of Advanced Energy Materials Chemistry(Ministry of Education) Nankai UniversityTianjin 300071China CAS Key Laboratory of Carbon Materials.Institute of Coal Chemistry Chinese Academy of SciencesTaiyuan 030001ShanxiChina

The introduction of nitrogen heteroatoms into carbon materials is a facile and efficient strategy to regulate their reactivities and facilitate their potential applications in energy conversion and storage. However,most of nitrogen heteroatoms are doped into the bulk phase of carbon without site selectivity, which significantly reduces the contacts of feedstocks with the active dopants in a conductive scaffold. Herein we proposed the chemical vapor deposition of a nitrogen-doped graphene skin on the 3D porous graphene framework and donated the carbon/carbon composite as surface N-doped grapheme（SNG）. In contrast with routine N-doped graphene framework（NGF） with bulk distribution of N heteroatoms, the SNG renders a high surface N content of 1.81 at%, enhanced electrical conductivity of 31 S cm^（-1）, a large surface area of 1531 m^2 g^（-1）, a low defect density with a low I_D/I_G ratio of 1.55 calculated from Raman spectrum, and a high oxidation peak of 532.7 ℃ in oxygen atmosphere. The selective distribution of N heteroatoms on the surface of SNG affords the effective exposure of active sites at the interfaces of the electrode/electrolyte, so that more N heteroatoms are able to contact with oxygen feedstocks in oxygen reduction reaction or serve as polysulfide anchoring sites to retard the shuttle of polysulfides in a lithium–sulfur battery. This work opens a fresh viewpoint on the manipulation of active site distribution in a conductive scaffolds for multi-electron redox reaction based energy conversion and storage.

关键词： Nitrogen-doped graphene Chemical vapor deposition Oxygen reduction reaction Lithium-sulfur battery Porous carbon materials Exposure of active sites

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ADDITIONAL PRESSURE LOSSES OF SOLID-LIQUID FLOW IN AN OSCILLATING PIPELINE

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Journal of Hydrodynamics 2002年第1期14卷 75-80页

作者： Xia, jian-Xin huang, jia-Zhen Cent. of Environ. Sci. Peking Univ. Beijing 100871 China

Manganese nodules on the ocean bed become attractive mineral resources because of its huge commercial benefits. In the last decades, a set of hydraulic lifting system with pipeline has been developed to mining these particles. It is inevitable that lifting pipe will oscillate due to its operation and the motion properties of the solid in the two-phase flow will be changed because of the oscillating of pipe-line. The pressure gradient along the lifting pipeline was investigated with a series of experiments. At the same time, a new pressure drop prediction method on the basis of Lagrange simulation technique was worked out by use of an axial momentum balance and this method provides a way to predict the pressure loss of solid-liquid mixture. The results show that compared with the fixed pipe transportation, the pressure gradient of the oscillating pipe is greater than that of the fixed pipe because of the collision and unsteady friction between particles and the pipe wall due to the oscillating motion of the pipe. Moreover, it is found that the prediction results are in good agreement with those of the experiments.

关键词： Two phase flow Underwater mineral resources

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A modern and robust methodology for modeling anisotropic creep characteristics of Ni-based DS and SC superalloys

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Science China(Technological Sciences) 2014年第9期57卷 1802-1815页

作者： huang jia SHI DuoQi YANG XiaoGuang School of Energy and Power Engineering Beihang University

According to more recent work, the Wilshire equations have shown good prediction accuracy in a wide range of materials and stress-temperature conditions, particularly in extrapolation of short term results to long term predictions. In the current paper, this methodology was further developed for modeling anisotropic creep characteristics （i.e. minimum creep strain /~n, stress rupture life q and time to a specified strain t~） of four typical Ni-based directionally solidified （DS） and single crystal （SC） superalloys, where a simple orientation factor related to the ultimate tensile strength （UTS） was introduced. The application of these simplistic approaches showed that the anisotropic creep characteristics in a wide range of stress-temperature conditions can be accurately simulated. Meanwhile, during the application of the modified Wilshire equations, break points occurring at the specified stress levels agree well with the transition of creep deformation mechanisms occurring in different stress regions, which provides confidence for using this method.

关键词： stress rupture life anisotropy the minimum creep strain rate Ni-based superalloy prediction methodology

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