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Symmetrical Independence Tests for Two Random Vectors with Arbitrary Dimensional Graphs

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Acta Mathematica Sinica,English Series 2022年第4期38卷 662-682页

作者： jia min liu Gao Rong LI jian Qiang ZHANG Wang Li XU Center for Applied Statistics Renmin University of ChinaBeijing 100872P.R.China School of Statistics Beijing Normal UniversityBeijing 100875P.R.China

Test of independence between random vectors X and Y is an essential task in statistical *** type of testing methods is based on the minimal spanning tree of variables X and *** main idea is to generate the minimal spanning tree for one random vector X,and for each edges in minimal spanning tree,the corresponding rank number can be calculated based on another random vector *** resulting test statistics are constructed by these rank ***,the existed statistics are not symmetrical tests about the random vectors X and Y such that the power performance from minimal spanning tree of X is not the same as that from minimal spanning tree of *** addition,the conclusion from minimal spanning tree of X might conflict with that from minimal spanning tree of *** order to solve these problems,we propose several symmetrical independence tests for X and *** exact distributions of test statistics are investigated when the sample size is ***,we study the asymptotic properties of the statistics.A permutation method is introduced for getting critical values of the *** with the existing methods,our proposed methods are more efficient demonstrated by numerical analysis.

关键词： Exact distribution minimal spanning tree asymptotic distribution symmetrical independence test

Compact TE-pass polarizer based on lithium-niobate-on-insulator assisted by indium tin oxide and silicon nitride

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Chinese Physics B 2023年第6期32卷 284-289页

作者：刘家敏张德龙 Department of Opto-electronics and Information Engineering School of Precision Instruments and Opto-electronics EngineeringKey Laboratory of Optoelectronic Information Technology(Ministry of Education)and Key Laboratory of Micro-Opto-Electro-Mechanical Systems(MOEMS)Technology(Ministry of Education)Tianjin UniversityTianjin 300072China

An indium tin oxide(ITO) and silicon nitride(Si_(3)N_(4)) assisted compact TE-pass waveguide polarizer based on lithiumniobate-on-insulator is proposed and numerically *** properly designing the ITO and Si_(3)N_(4) assisted structure and utilizing the epsilon-near-zero effect of ITO,the TM mode is strongly confined in the ITO layer with extremely high loss,while the TE mode is hardly affected and passes through the waveguide with low *** simulation results show that the polarizer has an extinction ratio of 22.5 dB and an insertion loss of 0.8 dB at the wavelength of 1.55 μm,and has an operating bandwidth of about 125 nm(from 1540 nm to 1665 nm) for an extinction ratio of>20 dB and an insertion loss of<0.95 ***,the proposed device exhibits large fabrication *** notably,the device is compact,with a length of only 7.5 μm,and is appropriate for on-chip applications.

关键词： polarizer lithium-niobate-on-insulator integrated optics devices optical waveguide

Enantioseparation of Aminoglutethimide by High-speed Countercurrent Chromatography Using Carboxymethly-β-cyclodextrin as Chiral Selector

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Chinese Chemical Letters 2006年第6期17卷 787-790页

作者： Ping AI jia Chuan liu min ZI Zhi Hua DENG Zhi Hong YAN Li ming YUAN Department of Chemistry Yunnan Normal University Kunming 650092

Enantioseparation of aminoglutethimide was performed by high-speed counter-current chromatography with a two-phase system composed of ethyl acetate： methanol： water = 10： 1： 9. The lower phase contained 20 mmol/L of carboxymethly-β-cyclodextrin as chiral selector. The enantiomers were separated in 1.2 h and identified by chiral HPLC. This method was very efficient for the chiral preparative separation.

关键词： High speed countercurrent chromatography enantioseparation aminoglutethimide,carboxymethly-β-cyclodextrin.

Amisulpride augmentation therapy improves cognitive performance and psychopathology in clozapine‑resistant treatment‑refractory schizophrenia:a 12‑week randomized,double‑blind,placebo‑controlled trial

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Military Medical Research 2023年第4期10卷 431-443页

作者： ming‑Huan Zhu Zhen‑Jing liu Qiong‑Yue Hu jia‑Yu Yang Ying Jin Na Zhu Ying Huang Dian‑Hong Shi min‑jia liu Hong‑Yang Tan Lei Zhao Qin‑Yu Lv Zheng‑Hui Yi Feng‑Chun Wu Ze‑Zhi Li Clinical Research Center for Mental Disorders School of MedicineShanghai Pudong New Area Mental Health CenterTongji UniversityShanghai 200124China Qingdao Mental Health Center Qingdao 266034ShandongChina Shanghai Mental Health Center Shanghai Jiao Tong University School of MedicineShanghai 200030China Department of Psychiatry the Affiliated Brain Hospital of Guangzhou Medical UniversityGuangzhou 510370China Guangdong Engineering Technology Research Center for Translational Medicine of Mental Disorders Guangzhou 510370China

Background:Although clozapine is an effective option for treatment-resistant schizophrenia(TRS),there are still 1/3 to 1/2 of TRS patients who do not respond to *** main purpose of this randomized,double-blind,placebocontrolled trial was to explore the amisulpride augmentation efficacy on the psychopathological symptoms and cognitive function of clozapine-resistant treatment-refractory schizophrenia(CTRS)***:A total of 80 patients were recruited and randomly assigned to receive initial clozapine plus amisulpride(amisulpride group)or clozapine plus placebo(placebo group).Positive and Negative Syndrome Scale(PANSS),Scale for the Assessment of Negative Symptoms(SANS),Clinical Global Impression(CGI)scale scores,Repeatable Battery for the Assessment of Neuropsychological Status(RBANS),Treatment Emergent Symptom Scale(TESS),laboratory measurements,and electrocardiograms(ECG)were performed at baseline,week 6,and week ***:Compared with the placebo group,amisulpride group had a lower PANSS total score,positive subscore,and general psychopathology subscore at week 6 and week 12(PBonferroni<0.01).Furthermore,compared with the placebo group,the amisulpride group showed an improved RBANS language score at week 12(PBonferroni<0.001).Amisulpride group had a higher treatment response rate(P=0.04),lower scores of CGI severity and CGI efficacy at week 6 and week 12 than placebo group(PBonferroni<0.05).There were no differences between the groups in body mass index(BMI),corrected QT(QTc)intervals,and laboratory *** study demonstrates that amisulpride augmentation therapy can safely improve the psychiatric symptoms and cognitive performance of CTRS patients.

关键词： Schizophrenia Clozapine-resistant treatment-refractory schizophrenia Clozapine Amisulpride Augmentation

Variations, effectiveness and its associated factors of a nationwide web-based hypertension management training project in China: insights from a government-led campaign for 1.2 million lay health workers

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Journal of Geriatric Cardiology 2024年第7期21卷 733-750页

作者： Wei WANG Hai-Bo ZHANG jia-min liu Yan LI Na TIAN Lei YAN Jin-Xiao SONG Mei-Li LI Yue PENG Jing LI National Primary Health Care Hypertension Management Office National Clinical Research Center for Cardiovascular DiseasesNHC Key Laboratory of Clinical Research for Cardiovascular MedicationsFuwai HospitalNational Center for Cardiovascular DiseasesChinese Academy of Medical Sciences and Peking Union Medical CollegeBeijingChina

OBJECTIVES To evaluate the effectiveness of a large-scale,web-based,in-service hypertension management training project among lay health workers(LHWs) at primary care health(PHC) settings in China,and to examine the factors contributing to the variations of *** We used data from a web-based national hypertension management training project implemented in 2018,it was designed to facilitate LHWs to learn,understand,and apply the relevant knowledge and skills in hypertension management through providing training courses by use of the web-based platform with unified *** LHWs were required to participate in the exams before and after training to acquire scores for the use of evaluating their performance of hypertension management *** first used descriptive analysis to present the variations of effectiveness in hypertension management knowledge among LHWs by important ***,we used multilevel logistic regression to examine the individual and regional factors contributing to the variations and quantify the magnitude of how these factors affected training *** There were 1,208,610 LHWs who completed training and were ***,the scores of LHWs increased significantly from 62.87 ± 21.14 out of 100 in the pre-test to 88.30 ± 11.31 in the post-test by 25.43(95% confidence interval[CI]:25.40-25.47).Training contents involved in antihypertensive medication showed the lowest score(54.36) in the pre-test and soared the most after training,up to 84.22 by 54.94%.Individual factors associated with disparities in the knowledge of hypertension management decreased substantially after training,which included sex,age,education,practice type,professional level,and hierarchy of working *** variations were shown at the provincial level,with the majority of them being explained by factors at the regional *** Accessible web-based training modality,government efforts,accompa

关键词： hypertension workers nationwide

Regulation of circadian physiology and behavior by light in mammals:entrainment and masking

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Life Research 2024年第2期7卷 17-27页

作者： jia-min liu Ya-min Yang Wei Xu Xiao-Dong Li College of Life Sciences Wuhan UniversityWuhan 430062China

manifestation of circadian *** modern use of electric lights alters environmental lighting,leading to light exposure at inappropriate times to disturb circadian homeostasis for both human and *** light“pollution”and voluntary activities such as night shift work and transmeridian travelling have adverse consequences such as mood and metabolic disorders in *** the other hand,insufficient light exposure decreases neurotransmission from the locus ceruleus and dorsal raphe,leading to seasonal and nonseasonal affective disorders,while properly timed bright light is beneficial to mood and *** the critical and complex roles of light in mammalian physiology and behavior,it is essential to understand the underlying *** this review,we discuss the neural mechanisms through which light regulates and dysregulates circadian rhythms in mammals.

关键词： light circadian rhythms mammal

Prognostic value of tissue inhibitor of metalloproteinase-matrix metalloproteinase biomarkers at 30 days in patients with acute myocardial infarction without reperfusion therapy

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Chinese Medical Journal 2021年第4期134卷 481-483页

作者： Hui-Fang Pang Yan Gao jia-min liu jia-Peng Lu Yan-Ping Wang Si-ming Wang Li-Bo Hou Ao-Xi Tian Yan Gao National Clinical Research Center for Cardiovascular Diseases State Key Laboratory of Cardiovascular DiseaseFuwai HospitalChinese Academy of Medical Sciences and Peking Union Medical CollegeNational Center for Cardiovascular DiseasesBeijing 100037China

To the Editor:Ischemic coronary artery disease is the leading cause of heart failure(HF)which is a major public health burden *** the past decades,development of new pharmacological therapies and implementation of early reperfusion strategies have contributed to a significant reduction in mortality associated with acute myocardial infarction(AMI).However,improved survival in acute cardiac ischemic event has expanded the pool of patients prone to cardiac remodeling and adverse cardiovascular(CV)outcomes.

关键词： acute patients infarction

Enhanced post-combustion CO2 capture and direct air capture by plasma surface functionalization of graphene adsorbent

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Journal of Energy Chemistry 2025年第1期100卷 653-664页

作者： Rahul Navik Eryu Wang Xiao Ding Huang Yunyi Yiyu liu jia Li Guangdong-Hong Kong Joint Laboratory for Carbon Neutrality Jiangmen Laboratory of Carbon and Science and Technology Guangzhou HKUST Fok Ying Tung Research Institute The Hong Kong University of Science and Technology (Guangzhou) Carbon Neutrality and Climate Change Thrust Society Hub The Hong Kong University of Science and Technology (Guangzhou) Stoddart Institute of Molecular Science Department of Chemistry Zhejiang University

Graphene has enormous potential to capture CO2due to its unique properties and ***,graphene-based adsorbents have drawbacks of lower CO2adsorption capacity and poor *** work demonstrates a one-step rapid and sustainable N2/H2plasma treatment process to prepare graphene-based sorbent material with enhanced CO2adsorption *** treatment directly enriches amine species,increases surface area,and improves textural *** CO2adsorption capacity increases from 1.6 to 3.3 mmol/g for capturing flue gas,and from 0.14 to 1.3 mmol/g for direct air capture （DAC）.Importantly,the electrothermal property of the plasma-modified aerogels has been significantly improved,resulting in faster heating rates and significantly reducing energy consumption compared to conventional external heating for regeneration of *** aerogels display improved selectivity of 42 and 87 after plasma modification for 5 and 10 min,*** plasma-treated aerogels display minimal loss between 17%and 19% in capacity after 40 adsorption/desorption cycles,rendering excellent *** N2/H2plasma treatment of adsorbent materials would lower energy expenses and prevent negative effects on the global economy caused by climate change.

关键词： Carbon neutrality CO 2 capture Climate change Plasma treatment Graphene aerogel

Anomalous quality factor evolution of induced transparency in a virtualized coupled-oscillator system

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 148-155页

作者： Yunhan Yang Han jia Tuo liu Yuzhen Yang Jun Yang Key Laboratory of Noise and Vibration Research Institute of Acoustics Chinese Academy of Sciences University of Chinese Academy of Sciences State Key Laboratory of Acoustics Institute of Acoustics Chinese Academy of Sciences

The phenomenon of induced transparency, characterized by a high quality(Q) factor, holds significant importance in the fields of high-precision sensing, energy storage and wave manipulation. Conventional transparency systems are often constrained by the limited experimentally accessible parameter space and the lack of independent control over intrinsic parameters, thereby hindering advanced research on high-Q effects. Here we propose a virtualized coupled-oscillator system that enables reconfigurable induced transparency in the reflection spectrum. By virtually incorporating a pair of coupled oscillators into an individual acoustic meta-atom, we achieve the manipulation of induced transparency in a decoupled, wide-ranging, and elaborate manner. Exploiting the diverse evolutions across the intrinsic parameter space, we show experimentally a counter-intuitive increase in the Q-factor of the transparency window, which is attributed to the enhanced dissipation of the bright ***, a constant group delay at the center frequency is observed accompanying this evolution. Our work demonstrates an intriguing platform as well as a novel strategy to engineer high-Q induced transparency phenomenon, and paves the way towards applications in programmable acoustic sensors, filters and slow-wave devices.

关键词： induced transparency acoustic meta-atom high quality-factor scattering programmable intrinsic parameter