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HIGH VARIABILITY OF HUMAN CYTOMEGALOVIRUS UL150 OPEN READING FRAME IN LOW-PASSAGED CLINICAL ISOLATES

Chinese Medical Sciences Journal 2006年第2期21卷 69-74页

作者： Yao-hua ji Zheng-rong sun Qiang Ruan rong He Ying Qi Yan-ping Ma Yu-jing Huang Virus Laboratory .the Second Affiliated Hospital China Medical University Shenyang 110004

Objective To investigate the polymorphism of human cytomegalovirus (HCMV) UL150 open reading frame (ORF) in low-passaged clinical isolates, and to study the relationship between the polymorphism and different pathogenesis of congenital HCMV infection. Methods PCR was performed to amplify the entire HCMV UL150 ORF region of 29 clinical isolates, which had been proven containing detectable HCMV-DNA using fluorescence quantitative PCR. PCR amplification products were sequenced directly, and the data were analyzed. Results Totally 25 among 29 isolates were amplified, and 18 isolates were sequenced successfully. HCMV UL150 ORF sequences derived from congenitally infected infants were high variability. The UL150 ORF in all 18 clinical isolates shifted backward by 8 nucleotides leading to frame-shift, and contained a single nucleotide deletion at nucleotide position 226 compared with that of Toledo strain. The nucleotide diversity was 0.1% to 6.8% and the amino acid diversity was 0.2% to 19.2% related to Toledo strain. However, the nucleotide diversity was 0.1% to 6.4% and amino acid diversity was 0.2% to 8.3% by compared with Merlin strain. Compared with Toledo, 4 new cysteine residues and 13 additional posttranslational modification sites were observed in UL150 putative proteins of clinical isolates. Moreover, the UL150 putative protein contained an additional transmembrane helix at position of 4-17 amino acid related to Toledo. Conclusion HCMV UL150 ORF and deduced amino acid sequences of clinical strains are hypervariability. No obvious linkage between the polymorphism and different pathogenesis of congenital HCMV infection is found.

关键词： human cytomegalovirus gene UL150

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Antiferromagnetic interlayer coupling of (111)-oriented La_(0.67)Sr_(0.33)MnO_3/SrRuO_3 superlattices

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Chinese Physics B 2019年第3期28卷 347-350页

作者： Hui Zhang jing Zhang jin-E Zhang Fu-rong Han Hai-Lin Huang jing-Hua Song Bao-Gen Shen ji-rong sun Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of Sciences School of Physical Sciences University of Chinese Academy of Sciences

We report a strong antiferromagnetic(AFM) interlayer coupling in ferromagnetic La_(0.67)Sr_(0.33)MnO_3/SrRuO_3(LSMO/SRO) superlattices grown on(111)-oriented SrTiO_3 substrate. Unlike the(001) superlattices for which the spin alignment between LSMO and SRO is antiparallel in the in-plane direction and parallel in the out-of-plane direction, the antiparallel alignment is observed along both the in-plane and out-of-plane directions in the present sample. The low temperature hysteresis loop demonstrates two-step magnetic processes, indicating the coexistence of magnetically soft and hard components. Moreover, an inverted hysteresis loop was observed. Exchange bias tuned by the temperature and cooling field was also investigated, and positive as well as negative exchange bias was observed at the same temperature with the variation of the cooling field. A very large exchange field(H_(EB)) was observed and both magnitude and sign of the H_(EB)depend on the cooling field, which can be attributed to an interplay of Zeeman energy and AFM coupling energy at the interfaces. The present work shows the great potential of tuning a spin texture through interfacial engineering for the complex oxides whose spin state is jointly determined by strongly competing mechanisms.

关键词： transition metal oxide interlayer coupling exchange bias

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Machine learning technique for prediction of magnetocaloric effect in La(Fe,Si/Al)_(13)-based materials

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Chinese Physics B 2018年第6期27卷 92-97页

作者： Bo Zhang Xin-Qi Zheng Tong-Yun Zhao Feng-Xia Hu ji-rong sun Bao-Gen Shen State Key Laboratory of Magnetism Institute of Physics Chinese Academy of Sciences Beijing 100190 China School of Physical Sciences University of the Chinese Academy of Sciences Beijing 100049 China School of Materials Science and Engineering University of Science and Technology Beijing Beijing 100083 China

Data-mining techniques using machine learning are powerful and efficient for materials design, possessing great potential for discovering new materials with good characteristics. Here, this technique has been used on composition design for La（Fe,Si/Al）（13）-based materials, which are regarded as one of the most promising magnetic refrigerants in practice. Three prediction models are built by using a machine learning algorithm called gradient boosting regression tree（GBRT） to essentially find the correlation between the Curie temperature（TC）, maximum value of magnetic entropy change（（？SM）（max））,and chemical composition, all of which yield high accuracy in the prediction of TC and（？SM）（max）. The performance metric coefficient scores of determination（R^2） for the three models are 0.96, 0.87, and 0.91. These results suggest that all of the models are well-developed predictive models on the challenging issue of generalization ability for untrained data, which can not only provide us with suggestions for real experiments but also help us gain physical insights to find proper composition for further magnetic refrigeration applications.

关键词： La(Fe,Si/Al)13-based materials composition design machine learning magnetic refrigeration

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Spontaneous magnetization and magnetic domain texture of strontium hexaferrite in equilibrium state

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Rare Metals 2022年第9期41卷 3019-3026页

作者： Dan Liu Si-Da jiang Li-Chen Wang Ruo-Shui Liu Ming Zhang Tong-Yun Zhao Feng-Xia Hu ji-rong sun Bao-Gen Shen School of Artificial Intelligence Beijing Technology and Business UniversityBeijing100048China Space Environment Simulation Research Infrastructure Harbin Institute of TechnologyHarbin150001China Ganjiang Innovation Academy Chinese Academy of SciencesGanzhou341000China School of Physics Inner Mongolia University of Science and TechnologyBaotou014010China State Key Laboratory of Magnetism Institute of PhysicsChinese Academy of SciencesBeijing100190China

The spontaneous magnetization and equilibrium domain of SrFeOunder zero external field by micromagnetic simulation and experimental measurements were *** was found that the magnetic moment distribution was extremely sensitive to the grain size of strontium *** critical diameter from single-domain to multi-domain can be controlled by changing the thickness and diameter,which is the key to improve the permanent magnet properties.

关键词： properties. magnetization magnetic

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Composition design for (PrNd-La-Ce)2Fe(14)B melt-spun magnets by machine learning technique

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Chinese Physics B 2018年第4期27卷 460-464页

作者： Rui Li Yao Liu Shu-Lan Zuo Tong-Yun Zhao Feng-Xia Hu ji-rong sun Bao-Gen Shen State Key Laboratory of Magnetism Institute of Physics Chinese Academy of Sciences Beijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China

Data-driven technique is a powerful and efficient tool for guiding materials design,which could supply as an alternative to trial-and-error *** order to accelerate composition design for low-cost rare-earth permanent magnets,an approach using composition to estimate coercivity（H（cj）） and maximum magnetic energy product（BH）（max） via machine learning has been applied to（PrNd–La–Ce）2Fe（14）B melt-spun magnets.A set of machine learning algorithms are employed to build property prediction models,in which the algorithm of Gradient Boosted Regression Trees is the best for predicting both H（cj） and（BH）（max）,with high accuracies of R^2= 0.88 and 0.89,*** the best models,predicted datasets of H（cj） or（BH）max in high-dimensional composition space can be *** these virtual datasets could provide efficient guidance for materials design,and facilitate the composition optimization of 2：14：1 structure melt-spun *** with magnets＇ cost performance,the candidate cost-effective magnets with targeted properties can also be accurately and rapidly *** data analytics,which involves property prediction and composition design,is of great time-saving and economical significance for the development and application of La Ce-containing melt-spun magnets.

关键词： permanent magnet materials design machine learning property prediction

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Magnetic properties of misch-metal partially substituted Nd–Fe–B magnets sintered by dual alloy method

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Chinese Physics B 2018年第7期27卷 521-526页

作者： jie-Fu Xiong rong-Xiang Shang Yan-Li Liu Xin Zhao Wen-Liang Zuo Feng-Xia Hu ji-rong sun Tong-Yun Zhao Ren-jie Chen Bao-Gen Shen State Key Laboratory of Magnetism Institute of Physics Chinese Academy of Sciences Beijing 100190 China University of Chinese Academy of Sciences Beijing 100049 China Key Laboratory of Magnetic Materials and Devices Ningbo Institute of Materials Technology and Engineering Chinese Academy of Sciences Ningbo 315201 China

The misch-metal （MM） partially substituted Nd-Fe-B sintered magnets were fabricated by the dual alloy method, and the crystal structure, microstructure, and magnetic properties were analyzed comprehensively. X-ray diffraction （XRD） reveals that the increasing content of the MM has an inconsiderable effect on the crystallographic alignment of the magnets. Grains of the two main phases are uniformly distributed, and slightly deteriorate on the grain boundary. Due to the diffusion between the adjacent grains, the MM substituted Nd-Fe-B magnets contain three types of components with different Ce/La concentrations. Moreover, the first-order reversal curve （FORC） diagram is introduced to analyze the magnetization reversal process, coercivity mechanism, and distribution of reversal field in magnetic samples. The analysis indicates that there are two major reversal components, corresponding to the two different main phases. The domain nucleation and growth are determined to be the leading mechanism in controlling the magnetization reversal processes of the magnets sintered by the dual alloy method.

关键词： misch-metal first order reversal curve the dual alloy method magnetization reversal process

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High performance RE–Fe–B sintered magnets with high-content misch metal by double main phase process

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Chinese Physics B 2020年第10期29卷 494-500页

作者： Yan-Li Liu Qiang Ma Xin Wang jian-Jun Zhou Tong-Yun Zhao Feng-Xia Hu ji-rong sun Bao-Gen Shen State Key Laboratory of Magnetism Institute of PhysicsChinese Academy of SciencesBeijing 100190China School of Science Inner Mongolia University of Science and TechnologyBaotou 014010China University of Chinese Academy of Sciences Beijing 100049China

Double main phase process is applied to fabricate [(Pr, Nd)1 – xMMx]13.8FebalM1.5B5.9 (x = 0.5 and 0.7;M = Cu, Al, Co, and Nb) sintered magnets with high misch metal (MM) content. In comparison to the magnets by single main phase process, the enhanced magnetic properties have been achieved. For magnets of x = 0.7, Hcj increases to 371.9 kA/m by 60.5%, and (BH)max is significantly enhanced to 253.3 kJ/m3 by 56.9%, compared with those of the single main phase magnets of the same nominal composition. In combination with minor loops and magnetic recoil curves, the property improvement of magnets with double main phase method is well explained. As a result, it is demonstrated that double main phase technology is an effective approach to improve the permanent magnetic properties of MM based sintered magnets.

关键词： misch maetal double main phase process magnetic properties coercivity

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Thermodynamic criterion for searching high mobility two-dimensional electron gas at KTaO_(3)interface

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Chinese Physics B 2021年第7期30卷 70-73页

作者： Wen-Xiao Shi Hui Zhang Shao-jin Qi jin-E Zhang Hai-Lin Huang Bao-Gen Shen Yuan-Sha Chen ji-rong sun Beijing National Laboratory for Condensed Matter Physics and Institute of Physics Chinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China Fujian Innovation Academy Chinese Academy of SciencesFuzhou 350108China Songshan Lake Materials Laboratory Dongguan 523808China Spintronics Institute University of JinanJinan 250022China

Two-dimensional electron gases(2 DEGs)formed at the interface between two oxide insulators present a promising platform for the exploration of emergent *** most of the previous works focused on SrTiO_(3-)based 2 DEGs,here we took the amorphous-ABO_(3)/KTaO_(3)system as the research object to study the relationship between the interface conductivity and the redox property of B-site metal in the amorphous *** criterion of oxide-oxide interface redox reactions for the B-site metals,Zr,Al,Ti,Ta,and Nb in conductive interfaces was revealed:the formation heat of metal oxide,ⅢH_(f)^(o),is lower than-350 kJ/(mol O)and the work function of the metalΦis in the range of 3.75 eV<Φ<4.4 ***,we found that the smaller absolute value ofⅢH_(f)^(o)and the larger value ofΦof the B-site metal would result in higher mobility of the two-dimensional electron gas that formed at the corresponding amorphous-ABO_(3)/KTaO_(3)*** finding paves the way for the design of high-mobility all-oxide electronic devices.

关键词： two-dimensional electron gas oxygen vacancies thermodynamic criterion Hall mobility

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Tuning magnetic anisotropy by interfacial engineering in La2/3Sr1/3Co1-xMnxO2.5+δ/La2/3Sr1/3MnO3/La2/3Sr1/3Co1-xMnxO2.5+δ trilayers

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Chinese Physics B 2020年第9期29卷 498-505页

作者： Hai-Lin Huang Liang Zhu Hui Zhang jin-E Zhang Fu-rong Han jing-Hua Song Xiaobing Chen Yuan-Sha Chen( jian-Wang Cai Xue-Dong Bai Feng-Xia Hu Bao-Gen Shen ji-rong sun Beijing National Laboratory for Condensed Matter Physics&Institute of Physics Chinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesBeijing 100049China Songshan Lake Materials Laboratory Dongguan 523808China

Grouping different oxide materials with coupled charge, spin, and orbital degrees of freedom together to form heterostructures provides a rich playground to explore the emergent interfacial phenomena. The perovskite/brownmillerite heterostructure is particularly interesting since symmetry mismatch may produce considerable interface reconstruction and unexpected physical effects. Here, we systemically study the magnetic anisotropy of tensely strained La2/3Sr1/3Co1-xMnxO2.5+δ/La2/3Sr1/3MnO3/La2/3Sr1/3Co1-xMnxO2.5+δ trilayers with interface structures changing from perovskite/brownmillerite type to perovskite/perovskite type. Without Mn doping, the initial La2/3Sr1/3CoO2.5+δ/La2/3Sr1/3MnO3/La2/3Sr1/3CoO2.5+δ trilayer with perovskite/brownmillerite interface type exhibits perpendicular magnetic anisotropy and the maximal anisotropy constant is 3.385×106 erg/cm3, which is more than one orders of magnitude larger than that of same strained LSMO film. By increasing the Mn doping concentration, the anisotropy constant displays monotonic reduction and even changes from perpendicular magnetic anisotropy to in-plane magnetic anisotropy, which is possible because of the reduced CoO4 tetrahedra concentration in the La2/3Sr1/3Co1-xMnxO2.5+δ layers near the interface. Based on the analysis of the x-ray linear dichroism, the orbital reconstruction of Mn ions occurs at the interface of the trilayers and thus results in the controllable magnetic anisotropy.

关键词： perovskite/brownmillerite heterostructure magnetic anisotropy orbital reconstruction

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Evolution of electrical and magnetotransport properties with lattice strain in La0.7Sr0.3MnO3 film

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Chinese Physics B 2020年第9期29卷 429-434页

作者： Zhi-Bin Ling Qing-Ye Zhang Cheng-Peng Yang Xiao-Tian Li Wen-Shuang Liang Yi-Qian Wang Huai-Wen Yang ji-rong sun College of Physics&State Key Laboratory Qingdao UniversityQingdao 266071China Beijing National Laboratory for Condensed Matter Physics Institute of PhysicsChinese Academy of SciencesBeijing 100190China

In this paper,we investigate the effects of lattice strain on the electrical and magnetotransport properties of La0.7Sr0.3MnO3(LSMO)films by changing film thickness and *** electrical properties,a resistivity upturn emerges in LSMO films,i.e.,LSMO/STO and LSMO/LSAT with small lattice strain at a low temperature,which originates from the weak localization *** film thickness weakens the weak localization effect,resulting in the disappearance of resistivity *** in LSMO films with a large lattice strain(i.e.,LSMO/LAO),an unexpected semiconductor behavior is observed due to the linear *** magnetotransport properties,an anomalous in-plane magnetoresistance peak(pMR)occurs at low temperatures in LSMO films with small lattice strain,which is caused by two-dimensional electron gas(2DEG).Increasing film thickness suppresses the 2DEG,which weakens the ***,it is found that the film orientation has no influence on the formation of *** in LSMO/LAO films,the 2DEG cannot form due to the existence of linear *** work can provide an efficient way to regulate the film transport properties.

关键词： LSMO film lattice strain electrical transport magnetotransport

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