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对《促进发展的投资便利化协定》的评价及中国的因应策略

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国际商务研究 2025年第1期46卷 46-58页

作者：李轩东北师范大学吉林长春130117

经过世界贸易组织多年的努力,2024年2月,《促进发展的投资便利化协定》被宣布正式达成,这是世界贸易组织在多边投资谈判领域中的重大突破。该协定在促进资本跨境自由流动、推动全球经济可持续发展、改善全球治理、缓解“南北不平衡”等... 详细信息

经过世界贸易组织多年的努力,2024年2月,《促进发展的投资便利化协定》被宣布正式达成,这是世界贸易组织在多边投资谈判领域中的重大突破。该协定在促进资本跨境自由流动、推动全球经济可持续发展、改善全球治理、缓解“南北不平衡”等方面都有重要意义。随着该协定的逐步完善和落实,全球更多的经济体将会受益于它带来的红利。但是,该协定在执行过程中也面临着各种挑战,诸如协定执行成本巨大、国际投资保护主义抬头等。中国作为该协定的主要发起国,要加强投资便利化的制度建设和功能建设,积极履行国际承诺,为实现全球经济可持续发展做出重要贡献。

关键词：世界贸易组织《促进发展的投资便利化协定》制度建设启示

Increased excitatory amino acid transporter 2 levels in basolateral amygdala astrocytes mediate chronic stress–induced anxiety-like behavior

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Neural Regeneration Research 2025年第6期20卷 1721-1734页

作者： Xirong Xu Shoumin xuan Shuai Chen Dan liu Qian Xiao jie Tu Shenzhen Key Laboratory of Neuroimmunomodulation for Neurological Diseases Shenzhen-Hong Kong Institute of Brain ScienceShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina CAS Key Laboratory of Brain Connectome and Manipulation Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina Guangdong Provincial Key Laboratory of Brain Connectome and Behavior the Brain Cognition and Brain Disease Institute(BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina University of Chinese of Academy of Sciences BeijingChina Faculty of life and Health Sciences Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong ProvinceChina

The conventional perception of astrocytes as mere supportive cells within the brain has recently been called into question by empirical evidence, which has revealed their active involvement in regulating brain function and encoding behaviors associated with ***, astrocytes in the basolateral amygdala have been found to play a role in the modulation of anxiety-like behaviors triggered by chronic stress. Nevertheless, the precise molecular mechanisms by which basolateral amygdala astrocytes regulate chronic stress–induced anxiety-like behaviors remain to be fully elucidated. In this study, we found that in a mouse model of anxiety triggered by unpredictable chronic mild stress, the expression of excitatory amino acid transporter 2 was upregulated in the basolateral amygdala. Interestingly, our findings indicate that the targeted knockdown of excitatory amino acid transporter 2 specifically within the basolateral amygdala astrocytes was able to rescue the anxiety-like behavior in mice subjected to stress. Furthermore, we found that the overexpression of excitatory amino acid transporter 2 in the basolateral amygdala, whether achieved through intracranial administration of excitatory amino acid transporter 2agonists or through injection of excitatory amino acid transporter 2-overexpressing viruses with GfaABC1D promoters, evoked anxiety-like behavior in mice. Our single-nucleus RNA sequencing analysis further confirmed that chronic stress induced an upregulation of excitatory amino acid transporter 2 specifically in astrocytes in the basolateral amygdala. Moreover, through in vivo calcium signal recordings, we found that the frequency of calcium activity in the basolateral amygdala of mice subjected to chronic stress was higher compared with normal *** knocking down the expression of excitatory amino acid transporter 2 in the basolateral amygdala, the frequency of calcium activity was not significantly increased, and anxiety-like behavior was ob

关键词： anxiety astrocytes basolateral amygdala behavior dihydrokainic acid excitatory amino acid transporter 2 fiber photometry glutamate LDN-212320 transporter

主客观组合权重-TOPSIS-k-means++法内涝风险评估

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中国给水排水 2024年第5期40卷 130-136页

作者：郭鑫宇杨敬畏厉智成王洋程树辉李继选北京市市政工程设计研究总院有限公司北京100082 舞川环境科技<上海>有限公司上海201821

内涝风险较高是多数城镇面临的问题。以某感潮城镇片区为例,基于InfoWorks ICM建立的雨水管网-河段一二维耦合模型计算结果,利用地理信息系统(GIS)的栅格分析和邻域分析技术对孕灾环境危险性和易损性指标进行量化,最后运用GIS空间连接... 详细信息

内涝风险较高是多数城镇面临的问题。以某感潮城镇片区为例,基于InfoWorks ICM建立的雨水管网-河段一二维耦合模型计算结果,利用地理信息系统(GIS)的栅格分析和邻域分析技术对孕灾环境危险性和易损性指标进行量化,最后运用GIS空间连接功能进行图层叠加。采用耦合熵权法和层次分析法计算各指标的组合权重,积水深度、积水流速、与幼儿园的距离、与医院的距离、GDP密度和人口密度的权重分别为0.365、0.177、0.084、0.088、0.084、0.202。构建基于主客观组合权重-TOPSIS-k-means++的内涝风险评估模型,并与主客观组合权重-加权评分-k-means++方法对比,验证了该方法的有效性。研究结果表明,综合考虑危险性和易损性指标,运用k-means++方法对风险等级进行聚类分析可为片区雨水管渠设计和内涝点整治提供综合性科学依据。

关键词：内涝风险评估 TOPSIS 熵权法层次分析法 k-means++

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电商平台用户再购物行为的预测研究

计算机科学 2020年第S1期47卷 424-428页

作者：吕泽宇李纪旋陈如剑陈东明东北大学软件学院沈阳110167

电商平台上用户的购物行为研究对于电商企业来说具有重要的商业应用价值。文中针对购物者在同一电商平台上的再次消费行为的预测问题进行了研究。首先,针对用户与商家的行为和交易记录,基于特征工程方法设计了多种不同的行为预测特征,... 详细信息

电商平台上用户的购物行为研究对于电商企业来说具有重要的商业应用价值。文中针对购物者在同一电商平台上的再次消费行为的预测问题进行了研究。首先,针对用户与商家的行为和交易记录,基于特征工程方法设计了多种不同的行为预测特征,基于可视化等方法对比分析了预测特征的重要性和特点,进行了属性筛选;然后,基于提出的预测特征设计使用了多种不同算法训练预测模型。实验研究表明,多lightGBM模型的融合方法能够达到很高的再购物行为预测准确度,其AUC值能够达到0.7018,同时,基于这种方法实现的预测器只需要少数特征就能对预测结果产生很好的贡献。研究的数据来源是开源的真实大数据,研究成果具有应用和学术双重价值。

关键词：再次购物行为预测特征工程特征可视化融合模型

义务、自律与至善——康德伦理思想中的几个重要范畴分析

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湛江师范学院学报 2006年第4期27卷 1-5页

作者：吕耀怀李季璇中南大学政治学与行政管理学院湖南长沙410083

在康德看来,真正的道德行为不仅必须出于义务,而且也只能出于义务;只要是出于义务的行为,无论其效果如何,都必定是道德的行为。康德所谓的自律,提升了道德的主体性,但他又把自律变成了没有任何内容的空洞形式。康德把至善当作一种道德理... 详细信息

在康德看来,真正的道德行为不仅必须出于义务,而且也只能出于义务;只要是出于义务的行为,无论其效果如何,都必定是道德的行为。康德所谓的自律,提升了道德的主体性,但他又把自律变成了没有任何内容的空洞形式。康德把至善当作一种道德理想,当作一种在现实世界中难能而只有在彼岸世界才可能的圆满的善。但实际上,至善并不能解决道德与幸福的关系问题。

关键词：义务自律善康德道德

Universal design of three-dimensional porous graphene-iron based promotors for kinetically rationalized lithium-sulfur chemistry

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Journal of Energy Chemistry 2025年第1期100卷 192-200页

作者： Hua Gao Yunfeng Zhang Menglei Wang Ruoxuan Yang Shuai Feng xuan Cao Yaping Zhang Zhongyuan Lu Yingze Song State Key Laboratory of Environment-Friendly Energy Materials School of Materials and Chemistry Southwest University of Science and Technology School of Material Science and Engineering Henan University of Technology College of Chemistry and Chemical Engineering Taishan University

lithium-sulfur （li-S） batteries are widely deemed to be one of the most potential candidates for future secondary batteries because of their remarkable energy ***,notorious polysulfide shuttling and retarded sulfur reaction kinetics pose significant obstacles to the further application of li-S *** rationally designed highly active electrocatalysts can facilitate polysulfide conversion,the universal and scalable synthesis strategies need to be ***,a universal synthetic strategy to construct a series of three-dimensional （3D） porous graphene-iron （3DGr-Fe） based electrocatalysts involving 3DGr-FeP,3DGr-Fe3C,and 3DGr-Fe3Se4is exploited for manipulating the li-S redox *** has been observed that the implementation of a 3D porous Gr architecture leads to the well-designed conductive networks,while the uniformly dispersed iron nanoparticles introduce an abundance of active sites,fostering the lithium polysulfide conversion,thereby bolstering the overall electrochemical *** li-S battery with the 3DGr-Fe based electrocatalyst exhibits remarkable capacity retention of 94.8%upon 100 times at 0.2 ***,the soft-packaged li-S pouch cell based on such a 3DGr-Fe electrocatalyst delivers superior capacity of 1060.71 mA h g-1and guarantees for the continuous 30 min work of fan *** investigation gives comprehensive insights into the design,synthesis,and mechanism of 3DGr-Fe based electrocatalysts with high activity toward efficient and durable li-S batteries.

关键词： Redox reactions

西藏东北部比如盆地中生界油气苗的发现与意义

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地质通报 2010年第6期29卷 863-869页

作者：王先美祁开令伍新和江月星李吉选范志伟中国石油化工股份有限公司石油勘探开发研究院北京100083 中国石油化工股份有限公司南方分公司四川成都610041

比如盆地位于西藏的东北部。野外石油地质考察期间,在比如盆地发现了大量的地表油气苗。油气苗均为干沥青,出露层位集中在中-上侏罗统拉贡塘组与下白垩统多尼组中,其他层位未发现油气苗。镜下观察结果显示,拉贡塘组与多尼组碎屑岩骨架... 详细信息

比如盆地位于西藏的东北部。野外石油地质考察期间,在比如盆地发现了大量的地表油气苗。油气苗均为干沥青,出露层位集中在中-上侏罗统拉贡塘组与下白垩统多尼组中,其他层位未发现油气苗。镜下观察结果显示,拉贡塘组与多尼组碎屑岩骨架颗粒之间发育有油气包体与不发光沥青。从地表出露形态与特点看,干沥青主要分布于断裂带、裂缝等构造强变形的部位。与青藏高原腹地同类残留盆地对比,比如盆地新生代构造变形更强烈,盆地抬升并遭受剥蚀的幅度更大。由此,提出高原找油可能面临的诸多难题,应该重点关注新生代构造与构造地貌演化对油气藏的影响。

关键词：西藏比如盆地中生界地表油气苗强变形带油气散失构造演化

Cross-subcarrier precoder design for massive MIMO-OFDM downlink with symplectic optimization

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Science China(Information Sciences) 2025年

作者： Yu-xuan ZHANG An-An LU Xiang-Gen XIA Xi-Qi GAO National Mobile Communications Research Laboratory Southeast University Purple Mountain Laboratories Department of Electrical and Computer Engineering University of Delaware

We propose a cross-subcarrier precoder design(CSPD) for massive multiple-input multiple-output(MIMO) orthogonal frequency division multiplexing(OFDM) downlink. This work aims to significantly improve the channel estimation and signal detection performance by enhancing the smoothness of the frequency domain effective channel. This is accomplished by designing a few vectors known as the transform domain precoding vectors(TDPVs), which are then transformed into the frequency domain to generate the precoders for a set of subcarriers. To combat the effect of channel aging, the TDPVs are optimized under imperfect channel state information(CSI). The optimal precoder structure is derived by maximizing an upper bound of the ergodic weighted sum-rate(WSR) and utilizing the a posteriori beam-based statistical channel model(BSCM). To avoid the large-dimensional matrix inversion, we propose an algorithm with symplectic optimization. Simulation results indicate that the proposed cross-subcarrier precoder design significantly outperforms conventional methods.

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Resolving the developmental mechanisms of cardiac microthrombosis of SARS-CoV-2 based on single-cell transcriptome analysis

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Science China life Sciences 2025年第1期68卷 103-115页

作者： Xizi Luo Nan Zhang Yuntao liu Beibei Du xuan Wang Tianxu Zhao Bingqiang liu Shishun Zhao jiazhang Qiu Guoqing Wang State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Basic MedicineJilin University State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases Key Laboratory for Zoonosis Research of the Ministry of EducationCollege of Veterinary MedicineJilin University College of Mathematics Jilin University Bioinformatic Lab School of MathematicsShandong University Department of Cardiology China-Japan Union HospitalJilin University

The coronavirus disease 2019（COVID-19） outbreak caused by the severe acute respiratory syndrome coronavirus-2（SARS-CoV-2） developed into a global health emergency. Systemic microthrombus caused by SARS-CoV-2 infection is a common complication in patients with COVID-19. Cardiac microthrombosis as a complication of SARS-CoV-2 infection is the primary cause of cardiac injury and death in patietns with severe COVID-19. In this study, we performed single-cell sequencing analysis of the right ventricular free wall tissue from healthy donors,patients who died during the hypercoagulable period of characteristic coagulation abnormality（CAC）, and patients who died during the fibrinolytic period of CAC. We collected 61,187 cells enriched in 24 immune cell subsets and 13 cardiac-resident cell subsets. We found that in the course of SARS-CoV-2 infected heart microthrombus, MYO1EhighRASGEF1Bhighmonocyte-derived macrophages promoted hyperactivation of the immune system and initiated the extrinsic coagulation pathway by activating chemokines CCL3, CCL5. This series of events is the main cause of cardiac microthrombi following SARS-CoV-2 infection. In a SARS-CoV-2 infected heart microthrombus, excessive immune activation is accompanied by an increase in cellular iron content, which in turn promotes oxidative stress and intensifies intercellular competition. This induces cells to alter their metabolic environment, resulting in increased sugar uptake via the glycosaminoglycan synthesis pathway. In addition, high levels of reactive oxygen species generated by elevated iron levels promote increased endogenous malondialdehyde synthesis in a subpopulation of cardiac endothelial cells. This exacerbates endothelial cell dysfunction and exacerbates the coagulopathy process.

关键词： SARS-CoV-2 cardiac microthrombosis immune hyperactivation cell competition