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Primordial germ cell-mediated transgenesis and genome editing in birds

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Journal of Animal Science and Biotechnology 2018年第2期9卷 257-267页

作者： Jae yong Han Young Hyun park Department of Agricultural Biotechnology and Research Institute of Agriculture and Life Sciences College of Agriculture and Life Sciences Seoul National University Institute for Biomedical Sciences Shinshu University

Transgenesis and genome editing in birds are based on a unique germline transmission system using primordial germ cells(PGCs), which is quite different from the mammalian transgenic and genome editing system. PGCs are progenitor cells of gametes that can deliver genetic information to the next generation. Since avian PGCs were first discovered in nineteenth century, there have been numerous efforts to reveal their origin, specification, and unique migration pattern, and to improve germline transmission efficiency. Recent advances in the isolation and in vitro culture of avian PGCs with genetic manipulation and genome editing tools enable the development of valuable avian models that were unavailable before. However, many challenges remain in the production of transgenic and genome-edited birds,including the precise control of germline transmission, introduction of exogenous genes, and genome editing in ***, establishing reliable germline-competent PGCs and applying precise genome editing systems are critical current issues in the production of avian models. Here, we introduce a historical overview of avian PGCs and their application, including improved techniques and methodologies in the production of transgenic and genome-edited birds, and we discuss the future potential applications of transgenic and genome-edited birds to provide opportunities and benefits for humans.

关键词： Avian Genome editing Primordial germ cell Transgenesis

Noncommutative Versions of the Singer-Wermer Conjecture with Linear Left θ-derivations

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Acta Mathematica Sinica,English Series 2008年第11期24卷 1891-1900页

作者： yong Soo JUNG Kyoo Hong park Department of Mathematics Sun Moon University Asan Chungnam 336-708 Korea Department of Mathematics Education Seowon University Cheongju Chungbuk 361-742 Korea

The noncommutative Singer-Wermer conjecture states that every linear （possibly unbounded） derivation on a （possibly noncommutative） Banach algebra maps into its Jacobson radical. This conjecture is still an open q... 详细信息

关键词： linear left θ-derivation linear θ-derivation Jacobson radical nil radical

Selective Deoxygenation of Nitrones Mediated by Sm/CoCl_26H_2O Reductive System

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Chinese Chemical Letters 2001年第11期12卷 945-946页

作者： ji Ming ZHANG yong Min ZHANG Department of Chemistry Zhejiang University(Xixi Campus)Hangzhou 310028 State Key Laboratory of Organometallic Chemistry Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghai 200032

In the presence of metallic samariumcobalt (II) chloride hexahydrate, the nitrones can be reduced to the corresponding imines in moderate to high yields under mild and neutral conditions.

关键词： Nitrone samarium cobalt (II) chloride hexahydrate.

Comparison of clinical outcomes after femtosecond laser in situ keratomileusis in eyes with low or high myopia

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International Journal of Ophthalmology(English edition) 2020年第11期13卷 1780-1787页

作者： Su Hwan park Cheng-Ye Che Sung Il Kim Choul yong park Jong Heon Lee Young Hee Kim ji Won Jung Jong Soo Lee ji Eun Lee Department of Ophthalmology School of MedicinePusan National UniversityYangsan 50612Gyeongnam ProvinceRepublic of Korea Research Institute for Convergence of Biomedical Science and Technology Pusan National University Yangsan HospitalYangsan 50612Gyeongnam ProvinceRepublic of Korea Department of Ophthalmology the Affiliated Hospital of Medical CollegeQingdao UniversityQingdao 266003Shandong ProvinceChina Department of Ophthalmology Dongguk University Ilsan HospitalDongguk University College of MedicineGoyang 10326Gyeonggi ProvinceRepublic of Korea Busan Medical Center Busan 47527Republic of Korea BalGunNun Eye Hospital Busan 47195Republic of Korea

AIM:To compare the clinical results of femtosecond(FS)laser in situ keratomileusis(LASIK)in high myopic patients and low myopic ***:This study included 212 myopic eyes undergoing LASIK using a VisuMax 500kHz FS *** treated eyes were assigned to one of two groups according to preoperative manifest spherical refraction:low myopia group(A,>-4.0 D)and high myopia group(B,0.50 D in spherical equivalent from Iwk to 6mo postoperatively(P=0.005).In terms of postoperative astigmatism,each group had 89.1%and 76.6%within±0.50 D,respectively and there was significant difference(P=0.006).Group A tends to induce smaller HOAs than group ***:FS LASIK is effective and safe for correcting high myopia as well as low ***,high myopic eyes showed more postoperative astigmatism and HOAs which affect visual acuity.

关键词： femtosecond laser LASIK myopia

Effect of Subcritical Annealing Temperature on Microstructure and Mechanical Properties of SCM435 Steel

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Journal of Iron and Steel Research International 2015年第11期22卷 1031-1036页

作者： Cheng ji Lei WANG Miao-yong ZHU School of Materials and Metallurgy Northeastern University

The effect of subcritical annealing temperature on microstructure and mechanical properties of SCM435 steel was investigated through changing the heating and soaking temperature as 660 °C, 680 °C, 700 °C, 720 °C and 745 °C. The microstructure and mechanical properties of intercritically annealed specimens were analyzed. With increasing the subcritical annealing temperature from 660 °C to 720 °C, the spheroidization ratio gradually increased, and the mechanical properties, formability and Vickers hardness were improved. According to the comprehensive comparison of mechanical properties and formability, the subcritical process at soaking temperature of 680-720 °C could achieve similar annealing effect as that of intercritical process. Therefore, the subcritical annealing temperature could be set as 700 °C in practice, with the Ac1 temperature fluctuation within ±20 °C, and the applicability and stability of subcritical annealing were guaranteed in industrial application. The plant results of the cold heading showed that the subcritical annealing could replace original intercritical annealing successfully with significantly saving time and energy.

关键词： subcritical annealing spheroidization ratio SCM435 steel microstructure mechanical property formability

The Monotone Method for Controllability of the Nonlinear Evolution Systems

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Acta Mathematicae Applicatae Sinica 2011年第4期27卷 721-726页

作者： Yue LU yong LI Ming-ji LIU College of Mathematics Jilin University Changchun 130012 China

In this paper, we study the controllability of the nonlinear evolution systems. We establish the controllability results by using the monotone operator theory. No compactness assumptions are imposed in the main result... 详细信息

关键词： controllability monotone operator nonlinear control systems

Entropy of the Nonminimally Coupled Quantum Scalar Fields in a Stationary Axisymmetric Einstein-Maxwell Dilaton- Axion Black Hole

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Chinese Physics Letters 1999年第11期16卷 784-786页

作者： jiNG ji-liang WANG yong-jiu Department Physics and Institute of Physics Hu’nan Normal UniversityChangsha 410081 Astronomy and Applied Physics Department University of Science and Technology of ChinaHefei 230026

The statistical-mechanical entropy of the stationary axisymmetric Einstein-Maxwell dilaton-axion black hole is investigated by using the “brick wall” model in which the original Dirichlet condition is replaced by a scattering ansatz for the field functions at the event horizon and regularized with the Pauli-Villars scheme. It is also shown, for the Kerr black hole, that the statistical-mechanical entropy obtained from our derivation coincides with the one-loop correction to its thermodynamical entropy obtained by the conical singularity method.

关键词： method Einstein entropy

Incremental forming of free surface with magnesium alloy AZ31 sheet at warm temperatures

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中国有色金属学会会刊：英文版 2008年第A01期18卷 165-169页

作者： Y.H.ji J.J.park Department of Mechanical and System Design Engineering Hongik University

The formabilityof AZ31 sheet begins to increase drastically at 150℃.The incremental forming technique was thus applied to AZ31 sheet at 150℃to utilize the formability to its fullest capacity at the lowest possible temperature for forming applications.A surface scanning technique was used followed by the tool path generation to incrementally form an egg *** thorough examination of various tool paths,the surface was most successfully produced by forming an intermediate shape followed by a series of tool *** scale stickers were devised to improve the accuracy in the measurement of grid deformation.

关键词：金属材料数控成形加工 AZ31镁合金板材

Hydrodynamic cavitation as an efficient method for the formation of sub-100 nm O/W emulsions with high stability

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Chinese Journal of Chemical Engineering 2016年第10期24卷 1477-1480页

作者： Zhiliang Zhang Guangquan Wang yong Nie jianbing ji Zhejiang Provincal Key Laboratory of Biofuel College of Chemical EngineeringZhejiang University of Technology

Hydrodynamic cavitation,a newly developed process intensification technique,has demonstrated immense potential for intensifying diverse physical and chemical *** this study,hydrodynamic cavitation was explored as an efficient method for the formation of sub-100 nm oil-in-water(O/W) emulsions with high stability.O/W emulsion with an average droplet size of 27 nm was successfully *** average droplet size of O/W emulsions decreased with the increase of the inlet pressure,number of cavitation passes and surfactant *** formed emulsion exhibited admirable physical stability during 8 ***,the hydrodynamic cavitation method can be generalized to fabricate large varieties of O/W emulsions,which showed great potential for large-scale formation of O/W emulsions with lower energy consumption.

关键词： Hydrodynamic cavitation Emulsification Emulsions Droplet size Size distribution