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Impact of physical activity on health-related quality of life in osteoporotic and osteopenic postmenopausal women:A systematic review

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International Journal of Nursing Sciences 2015年第2期2卷 204-217页

作者： Xiao Xu Wei ji Xiu-Qiang Lv Yi-Chi Zhu ji-xiang zhao Lin-Zhong Miao School of Nursing Nanjing University of Chinese MedicineNanjingChina Department of Rheumatism Affiliated Hospital of Nanjing University of Traditional Chinese MedicineNanjingChina Nursing Department The First Hospital Affiliated to Soochow UniversitySuzhouChina Nursing Department Suzhou Municipal HospitalSuzhouChina Nursing Department Soochow University Affiliated Children's HospitalSuzhouChina

Objective:This meta-analysis included papers which evaluated the effects of physical activity on the health-related quality of life(HRQoL)of osteoporotic and osteopenic postmenopausal ***:Four English databases were searched for relevant randomized clinical trials(RTCs)published from 1970 to June,*** RCTs which used the Quality of Life Questionnaire of the European Foundation for Osteoporosis(QUALEFFO)as their outcome measure were selected for ***:Five RCTs were included in the final *** results showed that physical activity produced favorable effects in the HRQoL domains of physical function(p=0.001)and pain(p=0.01),but not in other *** with a single exercise,combined exercise produced more favorable effects on both physical function(p=0.0004)and pain(p=0.02).Short-term physical activity produced significant favorable results in all general health domains of HRQoL(p=0.01),whereas middle-term physical activity produced significant improvements only in the physical function(p<0.01)domains of ***-term physical activity produced significant improvement only in the pain domains of HRQoL(p<0.01),and only in the physical activity group when compared with a control ***:Only weak evidence supports the notion that physical activity effectively improves the health-related quality of life of osteoporotic and osteopenic postmenopausal *** with a single exercise,combined exercise produced favorable effects on both physical function and ***,different lengths of exercise produced improvements in different domains.

关键词： Health-related quality of life Osteoporosis Physical activity Postmenopause systematic review Randomized controlled trial

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高温金属熔体黏度突变探索

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物理学报 2018年第10期67卷 135-146页

作者：商继祥赵云波胡丽娜山东大学材料液固结构演变与加工教育部重点实验室济南250061

高温金属熔体的黏度是衡量液态金属动力学性质的一个重要指标,是高温金属熔体的基本物理性能之一.熔体的黏度在表征脆性系数、金属玻璃形成能力的大小和液-液相变现象方面起关键性作用.本文在介绍高温金属熔体黏度测量方法的基础上,综... 详细信息

高温金属熔体的黏度是衡量液态金属动力学性质的一个重要指标,是高温金属熔体的基本物理性能之一.熔体的黏度在表征脆性系数、金属玻璃形成能力的大小和液-液相变现象方面起关键性作用.本文在介绍高温金属熔体黏度测量方法的基础上,综合评述了单质、二元和多元合金黏度随温度的变化规律和黏度突变特征,分析了黏度突变研究的物理意义,并指出高温金属熔体黏度今后研究的发展方向。

关键词：高温金属熔体黏度动力学金属玻璃

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试论外语教学法在精读课中的灵活应用

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榆林学院学报 2014年第5期24卷 112-116页

作者：姬祥照榆林学院外语系陕西榆林719000

精读课是大学英语专业的基础课。如何有效地开展专业英语精读课教学是广大外语教学工作者所共同关注的问题。精读课教学目前主要存在的问题是教师没有专业的教学理论的指导,或刻板地受制于单一的教学法理论。通过分析精读课教学的现状,... 详细信息

精读课是大学英语专业的基础课。如何有效地开展专业英语精读课教学是广大外语教学工作者所共同关注的问题。精读课教学目前主要存在的问题是教师没有专业的教学理论的指导,或刻板地受制于单一的教学法理论。通过分析精读课教学的现状,提出精读课教学既要发挥传统教法的优势,同时要灵活地兼收并蓄各种教学法的精华,即应把新的教学方法与传统的教学方法进行有机的结合,这样才能圆满地完成精读课教学任务。

关键词：精读课教学教学法灵活应用

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Unlocking the stable interface in aqueous zinc-ion battery with multifunctional xylose-based electrolyte additives

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Journal of Energy Chemistry 2025年第1期100卷 770-778页

作者： Xiaoqin Li jian xiang Lu Qiu Xiaohan Chen Yinkun zhao Yujue Wang Qu Yue Taotao Gao Wenlong Liu Dan Xiao zhaoyu jin Panpan Li Institute for Advanced Study Chengdu University School of Mechanical Engineering Chengdu University College of Food and Biological Engineering Chengdu University Institute of Fundamental and Frontier Sciences University of Electronic Science and Technology of China College of Materials Science and Engineering Sichuan University

The growth of dendrites and the side reactions occurring at the Zn anode pose significant challenges to the commercialization of aqueous Zn-ion batteries（AZIBs）. These challenges arise from the inherent conflict between mass transfer and electrochemical kinetics. In this study, we propose the use of a multifunctional electrolyte additive based on the xylose（Xylo） molecule to address these issues by modulating the solvation structure and electrode/electrolyte interface, thereby stabilizing the Zn anode. The introduction of the additive alters the solvation structure, creating steric hindrance that impedes charge transfer and then reduces electrochemical kinetics. Furthermore, in-situ analyses demonstrate that the reconstructed electrode/electrolyte interface facilitates stable and rapid Zn2+ion migration and suppresses corrosion and hydrogen evolution reactions. As a result, symmetric cells incorporating the Xylo additive exhibit significantly enhanced reversibility during the Zn plating/stripping process, with an impressively long lifespan of up to 1986 h, compared to cells using pure ZnSO4electrolyte. When combined with a polyaniline cathode, the full cells demonstrate improved capacity and long-term cyclic stability. This work offers an effective direction for improving the stability of Zn anode via electrolyte design, as well as highperformance AZIBs.

关键词： Solvation

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Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease

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Neural Regeneration Research 2025年第10期20卷 2998-3012页

作者： Yuan zhao Yidan Zhang Xin Liu jian Zhang Ya Gao Shuyue Li Cui Chang xiang Liu Guofeng Yang Department of Geriatrics Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina Department of Neurosurgery The Second Hospital of Hebei Medical UniversityShijiazhuangHebei ProvinceChina

Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease *** proteins,DNA,mRNA,and lipids carried by exosomes reflect intracellular changes,and thus can serve as biomarkers for a variety of *** this study,we investigated alterations in the protein content of plasma exosomes derived from patients with Parkinson’s disease and the potential therapeutic roles of these proteins in Parkinson’s *** a tandem mass tag-based quantitative proteomics approach,we characterized the proteomes of plasma exosomes derived from individual patients,identified exosomal protein signatures specific to patients with Parkinson’s disease,and identified N-acetyl-alpha-glucosaminidase as a differentially expressed protein.N-acetyl-alpha-glucosaminidase expression levels in exosomes from the plasma of patients and healthy controls were validated by enzyme-linked immunosorbent assay and western *** results demonstrated that the exosomal N-acetyl-alpha-glucosaminidase concentration was not only lower in Parkinson’s disease,but also decreased with increasing Hoehn-Yahr stage,suggesting that N-acetyl-alpha-glucosaminidase could be used to rapidly evaluate Parkinson’s disease ***,western blot and immunohistochemistry analysis showed that N-acetyl-alpha-glucosaminidase levels were markedly reduced both in cells treated with 1-methyl-4-phenylpyridinium and cells overexpressingα-synuclein compared with control ***,N-acetyl-alpha-glucosaminidase overexpression significantly increased cell viability and inhibitedα-synuclein expression in 1-methyl-4-phenylpyridinium-treated *** together,our findings demonstrate for the first time that exosomal N-acetyl-alpha-glucosaminidase may serve as a biomarker for Parkinson’s disease diagnosis,and that N-acetyl-alpha-glucosaminidase may reduceα-synuclein expression and 1-methyl-4-phenylpyridinium-induced n

关键词： biomarker diagnosis exosomes N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

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激光熔凝处理对纯铁渗稀土层组织与耐蚀性能的影响

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中国稀土学报 2001年第4期19卷 346-349页

作者：许越纪红陈湘赵连城哈尔滨工业大学应用化学系黑龙江哈尔滨150001

通过SEM观察、X射线光电子能谱分析、电化学阻抗谱测定和阳极极化曲线的测试 ,探讨激光熔凝处理对纯铁渗稀土层组织与耐蚀性能的影响。结果表明 ,在一定条件下 ,激光熔凝处理可进一步提高纯铁渗稀土层组织的致密性与均匀性 ,显著提高稀... 详细信息

通过SEM观察、X射线光电子能谱分析、电化学阻抗谱测定和阳极极化曲线的测试 ,探讨激光熔凝处理对纯铁渗稀土层组织与耐蚀性能的影响。结果表明 ,在一定条件下 ,激光熔凝处理可进一步提高纯铁渗稀土层组织的致密性与均匀性 ,显著提高稀土渗层的耐蚀性。

关键词：稀土耐腐蚀性纯铁渗稀土层表面改性激光熔凝处理合金化

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Regulation and function of endoplasmic reticulum autophagy in neurodegenerative diseases

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Neural Regeneration Research 2025年第1期20卷 6-20页

作者： Xiu-Yun zhao De-En Xu Ming-Lei Wu ji-Chuan Liu Zi-Ling Shi Quan-Hong Ma Department of Neurology and Clinical Research Center of Neurological Disease the Second Affiliated Hospital of Soochow UniversitySuzhouJiangsu ProvinceChina Institute of Neuroscience&jiangsu Key Laboratory of Translational Research and Therapy for Neuro-Psycho-Diseases Soochow UniversitySuzhouJiangsu ProvinceChina Department of Neurology Jiangnan University Medical CenterWuxiJiangsu ProvinceChina

The endoplasmic reticulum,a key cellular organelle,regulates a wide variety of cellular *** reticulum autophagy,one of the quality control systems of the endoplasmic reticulum,plays a pivotal role in maintaining endoplasmic reticulum homeostasis by controlling endoplasmic reticulum turnover,remodeling,and *** this review,we briefly describe the endoplasmic reticulum quality control system,and subsequently focus on the role of endoplasmic reticulum autophagy,emphasizing the spatial and temporal mechanisms underlying the regulation of endoplasmic reticulum autophagy according to cellular *** also summarize the evidence relating to how defective or abnormal endoplasmic reticulum autophagy contributes to the pathogenesis of neurodegenerative *** summary,this review highlights the mechanisms associated with the regulation of endoplasmic reticulum autophagy and how they influence the pathophysiology of degenerative nerve *** review would help researchers to understand the roles and regulatory mechanisms of endoplasmic reticulum-phagy in neurodegenerative disorders.

关键词： autophagy endoplasmic reticulum endoplasmic reticulum autophagy endoplasmic reticulum quality control system endoplasmic reticulum receptors endoplasmic reticulum-associated degradation neurodegeneration neurodegenerative disease selective autophagy unfolded protein response

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股骨近端纤维结构不良1例及相关文献回顾

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中国骨伤 2015年第6期28卷 559-561页

作者：纪召祥齐欣涂世成王刚李叔强吉林大学白求恩第一医院骨关节外科吉林长春130021

患者,女,48岁,因左侧髋关节疼痛半年,加重伴活动受限1个月入院。患者半年前无明显诱因出现左髋关节慢性间断性疼痛,无夜间痛,经药物治疗及理疗后症状无好转。近1个月来疼痛加重,活动时疼痛明显加重,休息后好转,有夜间痛。今为求进一步... 详细信息

患者,女,48岁,因左侧髋关节疼痛半年,加重伴活动受限1个月入院。患者半年前无明显诱因出现左髋关节慢性间断性疼痛,无夜间痛,经药物治疗及理疗后症状无好转。近1个月来疼痛加重,活动时疼痛明显加重,休息后好转,有夜间痛。今为求进一步诊治入我院治疗。查体：跛行步态,左侧髋关节周围无红肿,皮温正常。左侧腹股沟中点压痛阳性,左侧股骨大粗隆处叩击痛阳性。左髋关节内旋受限,

关键词：股骨纤维结构不良病例报告

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内燃机配气机构噪声控制

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现代制造工程 2009年第11期 124-127,142页

作者：王厚记邓兆祥王攀重庆大学机械传动国家重点实验室重庆400030

为降低内燃机配气机构振动噪声，以某125型摩托车发动机配气机构为研究对象，利用高次多项式对凸轮型线进行优化设计。配气机构多体动力学仿真表明：优化后的配气机构没有出现“飞脱”和“反跳”现象，进、排气气门丰满程度有所增加，... 详细信息

为降低内燃机配气机构振动噪声，以某125型摩托车发动机配气机构为研究对象，利用高次多项式对凸轮型线进行优化设计。配气机构多体动力学仿真表明：优化后的配气机构没有出现“飞脱”和“反跳”现象，进、排气气门丰满程度有所增加，在各个转速下，气门的最大振动加速度降低了65％左右，气门与摇臂的撞击力有所降低，且气门与气门座间的撞击力明显下降。在此基础上，制作了凸轮样件并对优化前后配气机构进行声功率测试试验。结果表明：在测量转速范围内声功率级均降低1．5～2dB。

关键词：配气机构高次多项式凸轮型线声强法

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Double [5]carbohelicene: facile synthesis, chiroptical properties,isomerization study, and lasing application

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Science China Chemistry 2025年第1期 233-240页

作者： Peipei Liu Yantong Li Meng-xiang Wu Hao Kang Xiao-Li zhao Lin Xu Linlin Liu Xiaodong Li Junfeng Fang Zhiwei Fang Ya Cheng Hai-Bo Yang Huakang Yu Xueliang Shi State Key Laboratory of Petroleum Molecular & Process Engineering Shanghai Key Laboratory of Green Chemistry and Chemical ProcessesSchool of Chemistry and Molecular Engineering East China Normal University School of Physics and Optoelectronics South China University of Technology Institute of Polymer Optoelectronic Materials & Devices State Key Laboratory of Luminescent Materials & Devices South China University of Technology School of Physics and Electronic Science Engineering Research Center of Nanophotonics & Advanced Instrument Ministry of EducationEast China Normal University State Key Laboratory of Precision Spectroscopy School of Physics and Electronic Science East China Normal University

Double carbohelicenes have attracted considerable attention due to their aesthetic structures, distinct π-conjugation extension, inherent chirality, and intriguing optical and electronic properties. Herein, the concise de novo synthesis of a new double[5]carbohelicene 1 together with its chiroptical properties, isomerization process and lasing application is presented. 1 was synthesized by a simple protocol involving the formation of a 6,6′-bipentacene as the key intermediate. It is worth noting that1 existed as two diastereomers 1-PP/MM and 1-PM, which were successfully isolated and unambiguously confirmed by Xray crystallography. The optical resolution of the racemic 1-PP/MM was successfully achieved by chiral-phase highperformance liquid chromatography（HPLC）, and 1-PP and 1-MM were characterized by circular dichroism. Interestingly, it was found that 1-PP/MM could be completely isomerized to 1-PM upon heating, and the detailed thermodynamics and kinetics of the isomerization process were systematically investigated. 1-PM exhibited deep-red luminescence with emission maximum at 723 nm and fluorescence quantum yield as high as 32.95%. Consequently, we can showcase the lasing application of 1-PM by doping with epoxy resin to assemble a bottle microlaser spontaneously, which the lasing wavelength is 796.6 nm at a threshold of 0.8 m J cm-2. We believe that our studies, including the facile synthesis methodology, detailed isomerization studies, and lasing application, will shed some light on the design and synthesis of novel carbohelical systems with more functions.

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