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2023:A year of accomplishments for the 13 Science Citation Index Expanded-and Emerging Sources Citation Index-indexed Baishideng journals

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World Journal of Gastroenterology 2024年第1期30卷 9-16页

作者： jin-Lei Wang jia-Ping Yan jia-Ru Fan xiang Li Xu Guo jia-Wei Li Yun-Xiaojian wu jing-jie Wang Yu-Lu Chen Li Li Cong Lin Xin-Liang Qu ji-Hong Liu Yan-Liang Zhang Ying-Yi Yuan Hua-Ge Yu Yu-Xi Chen Yi-Xuan Cai xiang-Di Zhang Si Zhao Zi-Hang Xu Li Ma Na Ma Diao-Mei Guo Lian-Sheng Ma Baishideng Publishing Group Inc PleasantonCA 94566United States

In 2023,Baishideng Publishing Group(Baishideng)routinely published 47 openaccess journals,including 46 English-language journals and 1 Chinese-language *** successes were accomplished through the collective dedicated efforts of Baishideng staffs,Editorial Board Members,and Peer *** these 47 Baishideng journals,7 are included in the Science Citation Index Expanded(SCIE)and 6 in the Emerging Sources Citation Index(ESCI).With the support of Baishideng authors,company staffs,Editorial Board Members,and Peer Reviewers,the publication work of 2023 is about to be successfully *** editorial summarizes the 2023 activities and accomplishments of the 13 SCIEand ESCI-indexed Baishideng journals,outlines the Baishideng publishing policy changes and additions made this year,and highlights the unique advantages of Baishideng journals.

关键词： Baishideng Publishing Group Journal Impact Factor Open access Policy changes Policy additions Unique advantages Anxiety disorders Colorectal cancer Inflammatory bowel disease Hepatocellular carcinoma Gut microbes Atrial fibrillation

Naked-eye visualization of lymph nodes using fluorescence nanoprobes in non-human primate-animal models

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Nano Research 2024年第8期17卷 7404-7414页

作者： Xiaoyuan ji Binbin Chu Xiaofeng wu Zhiming Xia Airui jiang Chenyu Wang Zhiming Chen Danni Zhong Qiaolin Wei Bin Song Wanlin Li Yiling Zhong Houyu Wang Fenglin Dong Min Zhou Yao He Suzhou Key Laboratory of Nanotechnology and Biomedicine Jiangsu Key Laboratory for Carbon-Based Functional Materials&DevicesInstitute of Functional Nano and Soft Materials(FUNSOM)Soochow UniversitySuzhou 215123China School of Public Health Shanghai Jiao Tong University School of MedicineShanghai 200025China Zhejiang University-University of Edinburgh Institute(ZJU-UoE Institute) Zhejiang UniversityHaining 314400China Department of Ultrasound the First Affiliated Hospital of Soochow UniversitySuzhou 215006China State Key Laboratory(SKL)of Biobased Transportation Fuel Technology Zhejiang UniversityHangzhou 310027China School of Pharmacy Hangzhou Normal UniversityHangzhou 311121China Macao Translational Medicine Center Macao University of Science and TechnologyTaipa 999078MacaoChina Macao Institute of Materials Science and Engineering Macao University of Science and TechnologyTaipa 999078MacaoChina

Despite sufficient studies performed in non-primate animal models,there exists scanty information obtained from pilot trials in non-human primate animal models,severely hindering nanomaterials moving from basic research into clinical *** herein present a pioneering demonstration of nanomaterials based optical imaging-guided surgical operation by using macaques as a typical kind of non-human primate-animal ***,taking advantages of strong and stable fluorescence of the small-sized(diameter:~5 nm)silicon-based nanoparticles(SiNPs),lymphatic drainage patterns can be vividly visualized in a real-time manner,and lymph nodes(LN)are able to be sensitively detected and precisely excised from small animal models(e.g.,rats and rabbits)to non-human primate animal models(e.g.,cynomolgus macaque(Macaca fascicularis)and rhesus macaque(Macaca mulatta)).Compared to clinically used invisible near-infrared(NIR)lymphatic tracers(i.e.,indocyanine green(ICG);etc.),we fully indicate that the SiNPs feature unique advantages for naked-eye visible fluorescence-guided surgical operation in long-term *** toxicological analysis in macaque models further provides confirming evidence of favorable biocompatibility of the SiNPs *** expect that our findings would facilitate the translation of nanomaterials from the laboratory to the clinic,especially in the field of cancer treatment.

关键词： fluorescent silicon nanoparticles lymph node real-time naked-eye visualization macaque models

Dietary inflammatory index and its impact on severity and recurrence of Tourette syndrome in children

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World Journal of Psychiatry 2024年第8期14卷 1208-1215页

作者： Xiao-Ping wu Rong-Rong Fang Ting-Ting ji Department of Pediatrics Qingdao Chengyang People’s HospitalQingdao 266109Shandong ProvinceChina

BACKGROUND Tourette syndrome(TS)is a neurodevelopmental disorder characterized by the presence of motor and vocal tics,typically beginning in *** signifi-cant research efforts,the exact pathophysiology of TS remains incompletely *** studies suggest that inflammation may play a role in the severity and progression of TS,pointing to the potential influence of dietary and lifestyle factors on the ***,research on the specific connection between dietary inflammatory index(DII)and TS is still in its early stages,requir-ing additional clinical and epidemiological studies to validate the strength and specific mechanisms of this *** A total of 207 children diagnosed with TS in the pediatric department of Qingdao Chengyang People’s Hospital from January 2022 to January 2023 were *** were divided into stable and unstable groups based on follow-up *** enrollment,general information of the children[age,gender,body mass index(BMI),guardian’s education level,DII score,medical history,family history,academic stress,electronic device usage,medication,and disease progression]was assessed,and serum inflammatory levels were measured during follow-up *** scores and Yale Global Tic Severity Scale(YGTSS)scores were ***,based on YGTSS scores,the children were classified into mild,moderate,and severe *** DII,interleukin-6(IL-6),C-reactive protein(CRP),and tumor necrosis factor-alpha(TNF-α)levels in each group were *** Follow-up surveys were completed by 207 children and their *** them,117 children were in the stable group,and 90 were in the recurrent *** found no statistically significant differences in age,gender,comorbidities,BMI,and disease duration between the two groups(P>0.05).However,academic stress,electronic device usage,medication,guardian’s education level,and DII scores showed statistically significant differences between the groups(P

关键词： Dietary inflammation index Tourette's syndrome Correlation analysis Pro-inflammatory foods Inflammation levels Impact on severity and recurrence

Recent advances in chemical protein synthesis:method developments and biological applications

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Science China Chemistry 2024年第4期67卷 1060-1096页

作者： Suwei Dong ji-Shen Zheng Yiming Li Huan Wang Gong Chen Yongxiang Chen Gemin Fang Jun Guo Chunmao He Honggang Hu Xuechen Li Yanmei Li Zigang Li Man Pan Shan Tang Changlin Tian Ping Wang Bian wu Chuanliu wu Junfeng Zhao Lei Liu State Key Laboratory of Natural and Biomimetic Drugs and School of Pharmaceutical SciencesPeking UniversityBeijing 100191China Division of Life Sciences and Medicine University of Science and Technology of ChinaHefei 230027China School of Food and Biological Engineering Engineering Research Center of Bio-processMinistry of EducationHefei University of TechnologyHefei 230009China School of Chemistry and Chemical Engineering Nanjing UniversityNanjing 210023China State Key Laboratory of Elemento-Organic Chemistry Nankai UniversityTianjin 300071China Department of Chemistry Tsinghua UniversityBeijing 100084China Institute of Health Sciences Anhui UniversityHefei 230601China College of Chemistry Central China Normal UniversityWuhan 430079China School of Chemistry and Chemical Engineering South China University of TechnologyGuangzhou 510640China School of Medicine or Institute of Translational Medicine Shanghai UniversityShanghai 200444China Department of Chemistry The University of Hong KongHong Kong 999077China Shenzhen Graduate School Peking UniversityShenzhen 518055China School of Chemistry and Chemical Engineering Shanghai Jiao Tong UniversityShanghai 200240China School of Life Sciences University of Science and Technology of ChinaHefei 230026China Department of Chemical Biology Shanghai Jiao Tong UniversityShanghai 200240China Institute of Microbiology Chinese Academy of SciencesBeijing 100101China Department of Chemistry Xiamen UniversityXiamen 361005China School of Pharmaceutical Science Guangzhou Medical UniversityGuangzhou 511436China

The central dogma of modern biology underscores the pivotal roles proteins play in diverse biological processes,the study of which necessitates advanced methods to produce proteins with precision and *** protein synthesis,a powerful approach utilizing chemical reactions for the de novo construction of structurally accurate proteins,has emerged as a transformative tool for studying proteins and generating protein derivatives/mimics inaccessible by natural biological machinery,including post-translationally modified proteins,proteins comprised of unnatural amino acids,as well as mirror-image *** review summarizes recent strides in synthetic method developments for chemical protein synthesis,including innovative techniques in solid-phase peptide synthesis,the challenges presented by difficult sequences in either synthesis or folding and the exploration of novel ligation reactions using both chemical and enzymatic ***,the review also delves into newly developed protocols for site-selective protein modifications and the generation of stapled or macrocyclized peptides/miniproteins,highlighting the power of chemical methods to make structurally diverse *** applications of synthetic proteins in investigating post-translational modifications(phosphorylation,lipidation,glycosylation,ubiquitination,etc.),mirror-image biological processes and drug development are further ***,these topics provide a comprehensive overview of the current landscape of chemical protein synthesis.

关键词： chemical protein synthesis solid-phase peptide synthesis ligation reactions post-translational modifications mirror-image proteins peptide drugs

亚临界区圆柱绕流相干结构壁面模化混合RANS/LES模型

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物理学报 2024年第5期73卷 190-216页

作者：季梦尤云祥韩盼盼邱小平马乔吴凯健上海交通大学海洋工程国家重点实验室上海200240 上海君昱信息科技有限公司上海201800 上海交通大学三亚崖州湾深海科技研究院三亚572000

本文发展了一种具有壁面模化大涡模拟能力的雷诺平均纳维-斯托克斯(RANS)和大涡模拟(LES)方法的混合模型(简称WM-HRL模型),致力于对亚临界区雷诺数钝体绕流相干结构这类复杂流动现象进行高置信度的CFD解析模拟研究.该方法通过一个仅与... 详细信息

本文发展了一种具有壁面模化大涡模拟能力的雷诺平均纳维-斯托克斯(RANS)和大涡模拟(LES)方法的混合模型(简称WM-HRL模型),致力于对亚临界区雷诺数钝体绕流相干结构这类复杂流动现象进行高置信度的CFD解析模拟研究.该方法通过一个仅与当地网格空间分布尺寸有关的湍动能解析度指标参数rk即可实现从RANS到LES的无缝快速转换,并且RANS/LES混合转换区的边界位置及其各个分区(包括RANS区、LES区及RANS/LES混合转换区)对湍动能的解析能力均可通过两个指标参数nrk1-Q和nrk2-Q准则进行预先设定.通过对雷诺数Re=3900下圆柱绕流场的系列数值模拟研究,获得了能够高置信度解析并捕捉其绕流场中三维时空瞬态发展相干结构特性的湍动能解析度指标参数nrk1-Q和nrk2-Q准则的组合条件.研究表明,该WM-HRL模型不仅能够准确获取圆柱绕流场中剪切层小尺度K-H不稳定性结构的精细谱结构,而且在同一套网格系统下通过变化湍动能解析度指标参数nrk2-Q和nrk1-Q准则的组合条件,还可以精细解析圆柱绕流场中两类不同回流区的长度结构特征,及其对应的圆柱尾部近壁面处V和U形两个平均流向速度剖面的分支结构特性.

关键词：圆柱绕流相干结构 Kelvin-Helmholtz不稳定性混合RANS/LES模型

砂土中吸力筒基础抗拔数值模拟研究:系泊深度效应

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岩土力学 2024年第7期45卷 2187-2194页

作者：季慧彭宇吴则祥涂冬媚中国人民解放军32576部队广东广州510110 香港理工大学土木与环境工程学院中国香港999077 温州大学建筑工程学院浙江温州325000 温州理工学院建筑与土木工程学院浙江温州325000

针对锚线斜拉作用下吸力筒与砂土相互作用的微观特征仍不清楚这一问题,采用离散元(discrete element method,简称DEM)-有限元(finite element method,简称FEM)耦合数值方法,从宏观到微观角度分析系泊点深度对吸力筒基础抗拔性能的影响... 详细信息

针对锚线斜拉作用下吸力筒与砂土相互作用的微观特征仍不清楚这一问题,采用离散元(discrete element method,简称DEM)-有限元(finite element method,简称FEM)耦合数值方法,从宏观到微观角度分析系泊点深度对吸力筒基础抗拔性能的影响。在建模中,采用FEM中有限元网格来模拟吸力筒,采用DEM中颗粒来模拟吸力筒周围砂土,并通过控制滚轴运动来模拟锚线的拉作用。结果表明:吸力筒的拉力-位移曲线存在峰值拉力,且与不同系泊点深度下吸力筒运动模式有密切关系;吸力筒旋转方向、拔出位移的反转临界系泊深度点位于吸力筒从顶部往下h=66.7%深度附近(即吸力筒深度的2/3处,h为系泊深度)。此外,从颗粒尺度分析了土体变形及破坏行为,最终确定了吸力筒-颗粒土相互作用的破坏模式。研究结果表明,忽略锚线的系泊点深度将会导致误判吸力筒的承载能力及与土体的破坏模式。

关键词：吸力筒抗拔 DEM-FEM耦合深度效应土体变形

Emerging probing perspective of two-dimensional materials physics:terahertz emission spectroscopy

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Light(Science & Applications) 2024年第7期13卷 1278-1298页

作者： Yifei wu Yuqi Wang Di Bao Xiaonan Deng Simian Zhang Lin Yu-chun Shengxian Ke jianing Liu Yingjie Liu Zeli Wang Pingren Ham Andrew Hanna jiaming Pan Xinyue Hu Zhengcao Li ji Zhou Chen Wang State Key Laboratory of New Ceramics and Fine Processing Key Laboratory of Advanced Materials of Ministry of EducationSchool of Materials Science and EngineeringTsinghua University100084 BeijingChina Beijing Advanced Innovation Center for Integrated Circuits 100084 BeijingChina

Terahertz(THz)emission spectroscopy(TES)has emerged as a highly effective and versatile technique for investigating the photoelectric properties of diverse materials and nonlinear physical processes in the past few ***,research on two-dimensional(2D)materials has experienced substantial growth due to their atomically thin structures,exceptional mechanical and optoelectronic properties,and the potential for applications in flexible electronics,sensing,and ***,these materials offer advantages such as tunable bandgap,high carrier mobility,wideband optical absorption,and relatively short carrier *** applying TES to investigate the 2D materials,their interfaces and heterostructures,rich information about the interplay among photons,charges,phonons and spins can be unfolded,which provides fundamental understanding for future *** it is timely to review the nonlinear processes underlying THz emission in 2D materials including optical rectification,photon-drag,high-order harmonic generation and spin-to-charge conversion,showcasing the rich diversity of the TES employed to unravel the complex nature of these *** applications based on THz emissions,such as THz lasers,ultrafast imaging and biosensors,are also *** further,we analyzed the unique advantages of spintronic terahertz emitters and the future technological advancements in the development of new THz generation mechanisms leading to advanced THz sources characterized by wide bandwidth,high power and integration,suitable for industrial and commercial *** continuous advancement and integration of TES with the study of 2D materials and heterostructures promise to revolutionize research in different areas,including basic materials physics,novel optoelectronic devices,and chips for post-Moore’s era.

关键词： optoelectronic versatile exceptional

Non-contact wide-field viewing system-assisted scleral buckling surgery for retinal detachment in silicone oilfilled eyes

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International Journal of Ophthalmology(English edition) 2024年第4期17卷 761-766页

作者： Su-Lan wu Yi-Qi Chen Li-Jun Shen jian-Bo Mao Li Lin ji-Wei Tao Huan Chen Shi-An Zhang jia-Feng Yu Chen-Xi Wang Center for Rehabilitation Medicine Department of OphthalmologyZhejiang Provincial People’s HospitalAffiliated People’s HospitalHangzhou Medical CollegeHangzhou 310000Zhejiang ProvinceChina The Affiliated Eye Hospital of Wenzhou Medical University in Hangzhou Hangzhou 310000Zhejiang ProvinceChina

AIM:To evaluate scleral buckling(SB)surgery using a noncontact wide-field viewing system and 23-gauge intraocular illumination for the treatment of rhegmatogenous retinal detachment in silicone oil(SO)-filled ***:Totally 9 patients(9 eyes)with retinal detachment in SO-filled eyes were retrospectively *** patients underwent non-contact wide-field viewing system-assisted buckling surgery with 23-gauge intraocular *** was removed at an appropriate time based on *** patients were followed up for at least 3mo after SO *** reattachment,complications,visual acuity and intraocular pressure(IOP)before and after surgery were ***:Patients were followed up for a mean of 8.22mo(3-22mo)after SO *** patients had retinal *** the final follow-up,visual acuity showed improvement for 8 patients,and no change for 1 *** IOP was high in 3 patients before surgery,but it stabilized after treatment;it was not affected in the other *** of the patients had infections,hemorrhage,anterior ischemia,or any other ***:This new non-contact wide-field viewing system-assisted SB surgery with 23-gauge intraocular illumination is effective and safe for retinal detachment in SO-filled eyes.

关键词： non-contact wide-field viewing system scleral buckling silicone oil-filled retinal detachment

Genomic characterization of peritoneal lavage cytology-positive gastric cancer

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Chinese Journal of Cancer Research 2024年第1期36卷 66-77页

作者： Zhouqiao wu Tingfei Gu Changxian Xiong jinyao Shi jingpu Wang Ting Guo Xiaofang Xing Fei Pang Ning He Rulin Miao Fei Shan Yuan Zhou Ziyu Li jiafu ji Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing) Gastrointestinal Cancer CenterPeking University Cancer Hospital&InstituteBeijing 100142China Department of Biomedical Informatics Department of Physiology and PathophysiologyCenter for Noncoding RNA MedicineMOE Key Lab of Cardiovascular SciencesSchool of Basic Medical SciencesPeking UniversityBeijing 100191China State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers Beijing Key Laboratory of Carcinogenesis and Translational ResearchGastrointestinal Cancer CenterPeking University Cancer Hospital&InstituteBeijing 100142China

Objective: Positive peritoneal lavege cytology(CY1) gastric cancer is featured by dismal prognosis, with high risks of peritoneal metastasis. However, there is a lack of evidence on pathogenic mechanism and signature of CY1and there is a continuous debate on CY1 therapy. Therefore, exploring the mechanism of CY1 is crucial for treatment strategies and targets for CY1 gastric ***: In order to figure out specific driver genes and marker genes of CY1 gastric cancer, and ultimately offer clues for potential marker and risk assessment of CY1, 17 cytology-positive gastric cancer patients and 31matched cytology-negative gastric cancer patients were enrolled in this study. The enrollment criteria were based on the results of diagnostic laparoscopy staging and cytology inspection of exfoliated cells. Whole exome sequencing was then performed on tumor samples to evaluate genomic characterization of cytology-positive gastric ***: Least absolute shrinkage and selection operator(LASSO) algorithm identified 43 cytology-positive marker genes, while Mut Sig CV identified 42 cytology-positive specific driver genes. CD3G and CDKL2 were both driver and marker genes of CY1. Regarding mutational signatures, driver gene mutation and tumor subclone architecture, no significant differences were observed between CY1 and negative peritoneal lavege cytology(CY0).Conclusions: There might not be distinct differences between CY1 and CY0, and CY1 might represent the progression of CY0 gastric cancer rather than constituting an independent subtype. This genomic analysis will thus provide key molecular insights into CY1, which may have a direct effect on treatment recommendations for CY1and CY0 patients, and provides opportunities for genome-guided clinical trials and drug development.

关键词： Cytology gastric carcinoma peritoneal metastasis whole exome sequencing