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A new horizon for neuroscience:terahertz biotechnology in brain research

Neural Regeneration Research 2025年第2期20卷 309-325页

作者： Zhengping Pu Yu Wu Zhongjie Zhu Hongwei zhao Donghong Cui Shanghai Key Laboratory of Psychotic Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghaiChina Department of Psychiatry Kangci Hospital of JiaxingTongxiangZhejiang ProvinceChina Shanghai Synchrotron Radiation Facility Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiChina Key Laboratory of Interfacial Physics and Technology Shanghai Institute of Applied PhysicsChinese Academy of ScienceShanghaiChina National Facility for Protein Science in Shanghai Shanghai Advanced Research InstituteChinese Academy of SciencesShanghaiChina

Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain *** this article,we review the development of terahertz biotechnology and its applications in the field of *** evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin *** vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric *** the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic ***,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical *** review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.

关键词： biological effect brain neuron neuropsychiatry neuroscience non-thermal effect terahertz imaging terahertz radiation terahertz spectroscopy terahertz technology

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Flexible molecules dedicate to release strain of inverted inorganic perovskite solar cell

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Journal of Energy Chemistry 2025年第1期100卷 87-93页

作者： Hongrui Sun Sanlong Wang Pengyang Wang Yali Liu Shanshan Qi Biao Shi Ying zhao Xiaodan Zhang Institute of Photoelectronic Thin Film Devices and Technology Renewable Energy Conversion and Storage Center State Key Laboratory of Photovoltaic Materials and CellsNankai University Key Laboratory of Photoelectronic Thin Film Devices and Technology of Tianjin Haihe Laboratory of Sustainable Chemical Transformations Engineering Research Center of Thin Film Photoelectronic Technology of Ministry of Education Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)

The tensile strain in inorganic perovskite films induced by thermal annealing is one of the primary factors contributing to the inefficiency and instability of inorganic perovskite solar cells （IPSCs）,which reduces the defect formation ***,a flexible molecule 5-maleimidovaleric acid （5-MVA） was introduced as a strain buffer to release the residual strain of *** anhydride and carboxyl groups in 5-MVA interact strongly with the uncoordinated Pb2+through Lewis acid-base reaction,thus tightly“pull”the perovskite *** in-between soft carbon chain increased the structural flexibility of CsPbI2.85Br0.15perovskite materials,which effectively relieved the intrinsic internal strain of CsPbI2.85Br0.15,resisted the corrosion of external strain,and also reduced the formation of defects such as VIand *** addition,the introduction of 5-MVA improved crystal quality,passivated residual defects,and narrowed energy level ***,power conversion efficiency （PCE） of NiOxbased inverted IPSCs increased from 19.25% to 20.82% with the open-circuit voltage enhanced from 1.164 V to 1.230 *** release of strain also improved the stability of CsPbI2.85Br0.15perovskite films and devices.

关键词： Inverted inorganic perovskite solar cells Flexible molecules Strain release Crystallization Energy barrier High PCE

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Efficacy and safety of remimazolam in bronchoscopic sedation:A meta-analysis

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World Journal of Clinical Cases 2024年第6期12卷 1120-1129页

作者： Ying Zhou Cheng zhao Yi-Xun Tang ji-tong Liu Department of Anesthesiology The First Affiliated Hospital of Hunan Normal University(Hunan Provincial People’s Hospital)Changsha 410005Hunan ProvinceChina Department of Anesthesiology Zhangjiajie People's HospitalZhangjiajie 427000Hunan ProvinceChina

BACKGROUND Remimazolam is a new benzodiazepine used for procedural sedation and general *** studies have used remimazolam for bendable *** To assess the safety and efficacy of remimazolam for sedation in patients undergoing bendable bronchoscopy by performing a meta-analysis of randomized controlled trials(RCTs).METHODS We searched the EMBASE,PubMed,Cochrane Library,and Web of Science databases for RCTs on bendable bronchoscopic procedural sedation with remimazolam vs conventional sedatives(CS).RESULTS Five studies with 1080 cases were *** had the same sedation success rate compared with CS[relative risk(RR):1.35,95%CI:0.60-3.05,P=0.474,I2=99.6%].However,remimazolam was associated with a lower incidence of hypotension(RR:0.61;95%CI:0.40-0.95,P=0.027;I2=65.1%)and a lower incidence of respiratory depression(RR:0.50,95%CI:0.33-0.77,P=0.002,I2=42.3%).A subgroup analysis showed a higher success rate of sedation with remimazolam than midazolam(RR:2.45,95%CI:1.76-3.42,P<0.001).Compared with propofol,the incidence of hypotension(RR:0.45,95%CI:0.32-0.64,P<0.001,I2=0.0%),respiratory depression(RR:0.48,95%CI:0.30-0.76,P=0.002,I2=78.4%),hypoxemia(RR:0.36,95%CI:0.15-0.87,P=0.023),and injection pain(RR:0.04,95%CI:0.01-0.28,P=0.001)were *** Remimazolam is safe and effective during *** sedation success rate was similar to that in the CS ***,remimazolam has a higher safety profile,with fewer inhibitory effects on respiration and circulation.

关键词： Remimazolam Bronchoscopy Procedural sedation Meta-analysis

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Abiotic association of phthalic acid esters with humic acid of a sludge landfill

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Frontiers of Environmental Science & Engineering 2012年第6期6卷 778-783页

作者： Xiaoli CHAI Yongxia HAO Xin zhao Guixiang LIU Ying ZHU Rong ji Jun WU Huanhuan tong Youcai zhao State Key Laboratory of Pollution Control and Resource Reuse Tongji UniversityShanghai 200092China The Academy of Science of Shandong Province Jinan 250013China State Key Laboratory of Pollution Control and Resource Reuse Nanjing UniversityNanjing 210093China

The abiotic association between phthalic acid esters （PAEs） and humic substances （HS） in sludge landfill plays an important role in the fate and stability of PAEs. An equilibrium dialysis combined with 14C-labeling was used to study the abiotic association of two abundant PAEs （diethyl phthalate and di-n-butyl phthalate） with humic acid （HA） isolated from a sludge landfill with different stabilization times and different molecular weights. Ele- mental analysis and Fourier Transform Infrared Spectro- photometer （FTIR） suggested that high KA value of HA was related to the high aromatic content and large molecular weight of HA. The results indicated that the association strength of PAEs with HA depended on both the properties of the PAEs and the characteristics of HA. The KA values of the association were strongly dependent on solution pH, and decreased dramatically as the pH was increased from 3.0 to 9.0. The results suggested that non- specific hydrophobic interaction between PAEs and HA was the main contributor to the association of the PAEs with HA. The interactive hydrogen-bonds between the HA and the PAEs molecules may also be involved in the association.

关键词： abiotic association phthalic acid esters(PAEs) humic acid sludge landfill

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Propagation Characteristics of Exponential-Cosine Gaussian Vortex Beams

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Chinese Physics Letters 2021年第8期38卷 43-49页

作者： Xin tong Daomu zhao Zhejiang Province Key Laboratory of Quantum Technology and Device Department of PhysicsZhejiang UniversityHangzhou 310027China

We propose a controllable exponential-Cosine Gaussian vortex(ECGV)beam,which can evolve into the different beam profiles with three parameters:distance modulation factor(DMF),split modulation factor(SMF)and rotation modulation factor(RMF).When SMF is 0,the ECGV beam appears as a perfect single-ring vortex beam and the ring radius can be adjusted by the *** deduce from mathematics and give the reason for the single-ring *** SMF is not 0,the beam splits ***,SMF and RMF control the number,distance and rotation angle of the split,*** experiments verify the correctness of the theory.

关键词： theory rotation vortex

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Two episodic changes of trace fossils through the Permian-Triassic transition in the Meishan cores,Zhejiang Province

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Science China Earth Sciences 2010年第12期53卷 1885-1893页

作者： zhao XiaoMing tong jinNan Key Laboratory of Biogeology and Environmental Geology of Ministry of Education China University of GeosciencesWuhan 430074China Wuhan Institute of Geology and Mineral Resources Wuhan 430223China

Six ichnogenera,Chondrites,Palaeophycus,Planolites,Rhizocorallium,Skolithos,and Thalassinoides,were identified from the drilling cores near the Global Stratotype Section and Point(GSSP) of Permian-Triassic boundary at Meishan,Zhejiang *** ichnological indices,including abundance,bioturbation index,and disturbed depth of trace fossils,show two episodes of intense changes near the Permian-Triassic Boundary(PTB).Episode I occurred in Beds 25-27b when the ecologically complicate forms such as Chondrites,Skolithos,Rhizocorallium,and Thalassinoides disappeared hereafter,the bioturbation index reduced from 1-5 to 1-3,and the disturbed depth declined from 5-66 to 2-5 *** II took place at the base of Bed 33 with the disappearance of Palaeophycus and Planolites,and subsequent absence of trace fossils and bioturbation till the middle-upper part of Bed 41 when the disturbed structures reoccurred,but they are only tiny Planolites and the bioturbation index was never higher than 3 and the disturbed depth less than 4 *** I shows an intense change,corresponding to the main stage of the end-Permian mass extinction,whereas Episode II is relatively weak,corresponding to the epilogue of the mass extinction of trace makers in the Early ***,ichnofossils were dominated by surface tracks in simple ecological habit and *** phenomenon indicates that the Early Triassic benthonic fauna is changed from sessile benthic system to mobile benthic system after the end-Permian mass *** other words,the evolution of the trace fossils across the Permian-Triassic transition had an episodic process similar to the body *** addition,the change of ichnofabrics is well coincided with the negative excursion of carbon isotopes and the expansion of *** the results of physical and biogenic processes,trace fossils provided unique materials for the study of the biotic and environmental events,as well as their coupling evolution throu

关键词： trace fossils bioturbation index disturbed depth the Permian-Triassic transition two episodic evolution Meishan cores

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Influences of Leading-Edge Tubercle Amplitude on Airfoil Flow Field

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Journal of Thermal Science 2023年第4期32卷 1335-1344页

作者： zhao Ming WEI tong zhao Yijia LIU Zhengxian Department of Mechanics School of Mechanical EngineeringTianjin UniversityTianjin300350China Tianjin Key Laboratory of Modern Engineering Mechanics Tianjin UniversityTianjin300350China

The influences of leading-edge tubercle amplitude on airfoil flow field have been analyzed at high angle of *** accuracy of a large eddy simulation(LES)research is validated through quantitative comparisons with corresponding experimental ***,a proper orthogonal decomposition(POD)analysis has been carried out based on the unsteady flow field and the fluid mechanisms of corresponding POD modes have been ***,the influences of leading-edge tubercle amplitude have been *** the streamwise vorticity is larger than that of small amplitude cases,the momentum transfer process at peaks is more obvious for large amplitude,leading to delayed flow *** amplitude and wavelength play important roles in the generation of laminar separation bubble(LSB)at ***,the Karman vortex shedding process takes place at specific trough sections as pairs of periodic spatial structures exist in the dominant POD *** destruction of Karman vortex shedding process is strengthened along with the increase of amplitude.

关键词： leading-edge tubercle airfoil flow field proper orthogonal decomposition

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Lower Triassic and Induan-Olenekian Boundary in Chaohu,Anhui Province,South China

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Acta Geologica Sinica(English Edition) 2011年第2期85卷 399-407页

作者： tong jinnan zhao Laishi Key Laboratory of Biogeology and Environmental Geology of Ministry of Education China University of Geosciences Wuhan 430074 China State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences Wuhan 430074 China

Since the West Pingdingshan Section in Chaohu was proposed as the candidate of the Global Stratotype Section and Point of the Induan-Olenekian boundary in 2003, the Lower Triassic of Chaohu has been extensively studied. Based on the studies on the Lower Triassic of Chaohu, （1） a continuous conodont zonation is established, which has become an important reference for Lower Triassic stratigraphic correlation over the world; （2） the First Appearance Datum of conodont Neospathodus waageni was suggested and has been basically accepted as the primary marker to define the InduanOienekian boundary; （3） a characteristic Lower Triassic excursion of carbon isotopes was brought to light and has been proven to be not only an excellent index for the stratigraphic correlation but also a unique indication for the perturbation of ecological environments in the aftermath of the end-Permian mass extinction; （4） a magnetostratigraphic sequence is constituted with a certain biostratigraphic control in the low-latitude region and it presents an important correlation to the Boreal sequence; （5） a cyclostratigraphic study provides an alternative method to constrain the age of the chronostratigraphic units; and （6） a scheme of the Olenekian subdivision is recently suggested to define the boundary between the Smithian and Spathian Substages. In addition, Chaohu is also the type locality of the Chaohuan Stage, the upper stage of the Lower Triassic in the China Chronostratigraphic ***, the Lower Triassic of Chaohu is not only a classic sequence in South China, but also a key reference sequence to the investigation of the corresponding stratigraphy and geological events over the world. The recent achievements are viewed here for an overall understanding of the sequence. Then the current situation of the Induan-Olenekian and Smithian-Spathian boundaries is discussed to provide a reference for later works.

关键词： Lower Triassic Induan-Olenekian boundary Smithian-Spathian boundary Global Stratotype Section and Point Chaohu China

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DYNAMIC MODELING AND ACTIVE CONTROL OF FLEXIBLE PLATE BASED ON THE INPUT-OUTPUT DATA

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Acta Mechanica Solida Sinica 2013年第3期26卷 255-262页

作者： Yong Xie tong zhao Guoping Cai Department of Engineering Mechanics State Key Laboratory of Ocean EngineeringShanghai Jiaotong University

This paper studies the low-order dynamic modeling and active control of a flexible plate and provides experimental verification. First based on the input-output data of the sys- tem, the Markov parameters of the system are identified using the method of observer/Kalman filter identification （OKID）. Then a low-order state-space model is built using the eigensystem realization algorithm （ERA）. Finally, a linear quadratic Gaussian （LQG） controller is designed based on the low-order state-space model. Experimental results have proved the effectiveness and feasibility of the research.

关键词： flexible plate OKID ERA active control experiment

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Target Tracking Algorithm Using Finite-time Convergence Smooth Second-order Sliding Mode Controller for Mobile Robots

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Chinese Journal of Mechanical Engineering 2011年第3期24卷 414-419页

作者： GE Lianzheng zhao Lijun GAO tong State Key Laboratory of Robotics Technique and System Harbin Institute of Technology Harbin 150001 China

Target tracking control for wheeled mobile robot （WMR） need resolve the problems of kinematics model and tracking ***-order sliding mode control is a valid method used in the nonlinear tracking control system,which can eliminate the chattering of sliding mode *** there lacks the research of robustness and uncertain factors for high-order sliding mode *** address the fast convergence and robustness problems of tracking target,the tracking mathematical model of WMR and the target is *** on the finite-time convergence theory and second order sliding mode method,a nonlinear tracking algorithm is designed which guarantees that WMR can catch the target in finite *** the same time an observer is applied to substitute the uncertain acceleration of the target,then a smooth nonlinear tracking algorithm is *** on Lyapunov stability theory and finite-time convergence,a finite time convergent smooth second order sliding mode controller and a target tracking algorithm are designed by using second order sliding mode *** simulation results verified that WMR can catch up the target quickly and reduce the control discontinuity of the velocity of WMR.

关键词： mobile robots second order sliding mode finite-time convergence observer

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