检索结果-南通市图书馆

Managing adult-onset Still's disease in pregnancy:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2024年第16期12卷 2837-2841页

作者： ji-hyoun kang Division of Rheumatology Department of Internal MedicineChonnam National University Medical School&HospitalGwangju 61469South Korea

BACKGROUND Adult-onset Still’s disease(AOSD)is a rare systemic inflammatory disorder characterized by fever,arthritis,skin rash,and systemic *** etiology of AOSD is unknown;however,it is thought to be related to immune *** a rare disease,AOSD can significantly impact reproductive health,particularly during *** case study assesses the implications of pregnancy in a patient with AOSD,as well as the potential for heredity of the *** hemophagocytic lympho-histiocytosis(HLH)is a rare and lifethreatening disorder characterized by hyperinflammation and uncontrolled activation of immune cells,leading to multiple organ *** case report aimed to introduce neonatal HLH from a mother with *** SUMMARY This case study presents a 29-year-old female with AOSD who became pregnant and gave birth to a premature infant who was diagnosed with neonatal *** can significantly impact pregnancy and childbirth,as it may become more severe during pregnancy,with an increased risk of fetal loss and preterm *** management of AOSD during pregnancy involves the use of nonsteroidal anti-inflammatory drugs and glucocorticoids,as well as immunosuppressive agents in severe ***,the use of immunosuppressive agents during pregnancy may be associated with potential risks to the *** hereditary implications of AOSD are unclear;however,available evidence suggests that genetic factors may play a role in the disease *** AOSD can have significant implications for pregnancy and childbirth,including an increased risk of fetal loss and preterm *** HLH,a complication of AOSD in pregnancy,requires prompt diagnosis and *** with AOSD who are considering pregnancy should discuss their options with their healthcare provider and develop a management plan that addresses the potential risks to both mother and fetus.

关键词： Neonate Hemophagocytic lympho-histiocytosis Adult-onset Still’s disease Pregnancy Case report

Antiphospholipid syndrome with renal and splenic infarction after blunt trauma:A case report

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第26期10卷 9404-9410页

作者： Na-A Lee Eui-Sung Jeong Hyun-Seok Jang Yun-Chul Park ji-hyoun kang Jung-Chul Kim Young-Goun Jo Division of Trauma Department of SurgeryChonnam National University Medical School and HospitalGwangju 61469South Korea Division of Rheumatology Department of Internal MedicineChonnam National University Medical School and HospitalGwangju 61469South Korea

BACKGROUND In trauma patients,bleeding is an immediate major *** the same time,there are few cases of acute vascular occlusion after blunt trauma,and it is unclear what assessment and diagnosis should be considered for these ***,we describe a patient diagnosed with antiphospholipid syndrome after a hypercoagulable workup for acute renal and splenic vascular occlusion due to blunt *** SUMMARY A 20-year-old man was admitted to the emergency department with abdominal pain after hitting a tree while riding a sled 10 h *** had no medical *** investigations revealed occlusion of the left renal artery with global infarction of the left kidney and occlusion of branches of the splenic artery with infarction of the central portion of the *** revascularization of the left renal artery occlusion through percutaneous transluminal angioplasty failed due to difficulty in passing the wire through the total *** the presence of acute multivascular occlusions in a young man with low cardiovascular risk,additional laboratory tests were performed to evaluate *** results suggested a high possibility of antiphospholipid *** with a subcutaneous injection of enoxaparin was started and changed to oral warfarin after two *** diagnosis was confirmed,and he continued to visit the rheumatology outpatient clinic while taking *** A hypercoagulable workup can be considered in trauma patients with acute multivascular occlusion,especially in young patients with low cardiovascular risk.

关键词： Wounds and injuries Wounds Nonpenetrating Antiphospholipid syndrome Renal artery obstruction Splenic infarction Case reports

Brain age estimation:premise,promise,and problems

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第8期20卷 2313-2314页

作者： Jarrad Perron ji Hyun Ko Graduate Program in Biomedical Engineering Price Faculty of EngineeringUniversity of ManitobaWinnipegMBCanada PrairieNeuro Research Centre Kleysen Institute for Advanced MedicineHealth Sciences CentreWinnipegMBCanada Department of Human Anatomy and Cell Science Rady Faculty of Health SciencesUniversity of ManitobaWinnipegMBCanada

Premise:The com bined effects of modern healthcare practices which prolong lifespan and declining birthrates have created unprecedented changes in age demographics worldwide that are especially pronounced in Japan,South Korea,Europe,and North *** old age is the most significant predictor of dementia,global healthcare systems must rise to the challenge of providing care for those with neurodegenerative disorders.

关键词： estimation providing birth

Effect of cholesterol metabolism on hepatolithiasis

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第1期31卷 157-162页

作者： Lin Zheng Zi-Yu Ye Jun-ji Ma Department of Gastroenterology The Second Hospital of Hebei Medical UniversityHebei Key Laboratory of GastroenterologyHebei Institute of GastroenterologyHebei Clinical Research Center for Digestive DiseasesNo.215 Heping West RoadShijiazhuang 050000Hebei ProvinceChina

Surgical intervention is currently the primary treatment for hepatolithiasis;how-ever,some patients still experience residual stones and high recurrence rates after *** metabolism seems to play an important role in hepatoli-thiasis pathogenesis.A high cholesterol diet is one of the significant reasons for the increasing incidence of ***,regular diet and appropriate medical intervention are crucial measures to prevent hepatolithiasis and reduce recurrence rate after *** dietary cholesterol and drugs that increase cholesterol stone solubility are key therapeutic approaches in treating *** article discusses the cholesterol metabolic pathways related to the pathogenesis of hepatolithiasis,as well as food intake and targeted therapeutic drugs.

关键词： Hepatolithiasis Cholesterol metabolism High-fat diet 3-hydroxy-3-methylglutaryl-coenzyme A reductase Interlobular bile duct

Magneto‑Dielectric Synergy and Multiscale Hierarchical Structure Design Enable Flexible Multipurpose Microwave Absorption and Infrared Stealth Compatibility

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nano-Micro Letters 2025年第2期17卷 401-416页

作者： Chen Li Leilei Liang Baoshan Zhang Yi Yang Guangbin ji School of Electronic Science and Engineering Nanjing UniversityNanjing 210093People’s Republic of China College of Materials Science and Technology Nanjing University of Aeronautics and AstronauticsNanjing 210016People’s Republic of China

Developing advanced stealth devices to cope with radar-infrared(IR)fusion detection and diverse application scenarios is increasingly demanded,which faces significant challenges due to conflicting microwave and IR cloaking mechanisms and functional integration ***,we propose a multiscale hierarchical structure design,integrating wrinkled MXene IR shielding layer and flexible Fe_(3)O_(4)@C/PDMS microwave absorption *** top wrinkled MXene layer induces the intensive diffuse reflection effect,shielding IR radiation signals while allowing microwave to pass ***,the permeable microwaves are assimilated into the bottom Fe_(3)O_(4)@C/PDMS layer via strong magneto-electric *** theoretical and experimental optimization,the assembled stealth devices realize a near-perfect stealth capability in both X-band(8–12 GHz)and long-wave infrared(8–14μm)wavelength ***,it delivers a radar cross-section reduction of−20 dB m^(2),a large apparent temperature modulation range(ΔT=70℃),and a low average IR emissivity of ***,the optimal device demonstrates exceptional curved surface conformability,self-cleaning capability(contact angle≈129°),and abrasion resistance(recovery time≈5 s).This design strategy promotes the development of multispectral stealth technology and reinforces its applicability and durability in complex and hostile environments.

关键词： Microwave absorption Radar-infrared compatible stealth Wrinkled MXene Magneto-dielectric synergy Multifunction

在线全文

学校读者我要写书评

暂无评论

极端条件下含能材料的模拟研究思考

高压物理学报 2025年第1期39卷 010102-1-010102-27页

作者：姬广富中国工程物理研究院流体物理研究所冲击波物理与爆轰物理全国重点实验室四川绵阳　621999

含能材料在军事、民用和航天等领域具有广泛应用，极端条件下其物理化学性质会发生显著变化。通过模拟研究预测和优化含能材料性能具有重要意义，包括性能预测、优化设计、安全评估、成本效率控制等。为此，综述了极端条件下含能材料的... 详细信息

含能材料在军事、民用和航天等领域具有广泛应用，极端条件下其物理化学性质会发生显著变化。通过模拟研究预测和优化含能材料性能具有重要意义，包括性能预测、优化设计、安全评估、成本效率控制等。为此，综述了极端条件下含能材料的研究背景、基本性质、模拟研究方法及进展、关键问题以及相关实验研究进展。其中，详细介绍了量子力学、分子动力学、蒙特卡罗和有限元等模拟方法及其研究进展，阐述了高压、高温、激光作用和界面效应等极端条件下模拟研究的关键问题，并列举了含能材料在撞击感度、化学释能规律、3D打印、绿色电合成、爆轰机理和超高含能材料合成等方面的实验研究进展。通过遴选代表性研究，展示了模拟研究在实际问题中的应用和解决方案。同时，介绍了一些最新研究成果，以反映该领域的最新进展和未来趋势。此外，详细讨论了跨学科研究的实现方式以及含能材料在极端条件下的安全性问题，包括可能的风险和预防措施。

关键词：含能材料极端条件模拟研究高压高温激光作用

Enhanced Privacy Preserving for Social Networks Relational Data Based on Personalized Differential Privacy

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Electronics 2022年第4期31卷 741-751页

作者： kang Haiyan ji Yuanrui ZHANG Shuxuan School of Information Management Beijing Information Science and Technology University Computer School Beijing Information Science and Technology University

With the popularization and development of social software, more and more people join the social network, which produces a lot of valuable information, but also contains plenty of sensitive privacy information. To achieve the personalized privacy protection of massive social network relational data, a privacy enhancement method for social networks relational data based on personalized differential privacy is proposed. And a dimensionality reduction segmentation sampling(DRS-S)algorithm is proposed to implement this method. First, in order to solve the problem of inefficiency caused by the excessive amount of data in social networks, dimension reduction and segmentation are carried out to divide the data into groups. According to the privacy protection requirements of different users, we adopt sampling method to protect users with different privacy requirements at different levels, so as to realize personalized different privacy. After that, the noise is added to the protected data to satisfy the privacy budget. Then publish the social network data. Finally, the proposed algorithm is compared with the traditional personalized differential privacy(PDP) algorithm and privacy preserving approach based on clustering and noise(PBCN) in real data set, the experimental results demonstrate that the quality of privacy protection and data availability of DRS-S are better than that of PDP algorithm and PBCN algorithm.

关键词： Social network Privacy preserving Dimensionality reduction segmentation Personalized differential privacy DRS-S algorithm

Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第4期20卷 1178-1191页

作者： Wanxian Luo Chuanhui Xu Linxi Li Yunxiang ji Yezhong Wang Yingjia Li Yongyi Ye Department of Medicine Ultrasonics Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong ProvinceChina Institute of Neuroscience Department of NeurosurgeryThe Second Affiliated Hospital of Guangzhou Medical UniversityGuangzhouGuangdong ProvinceChina

Microglia,the primary immune cells within the brain,have gained recognition as a promising therapeutic target for managing neurodegenerative diseases within the central nervous system,including Parkinson’s *** perfluorocarbon droplets have been reported to not only possess a high oxygen-carrying capacity,but also exhibit remarkable anti-inflammatory ***,the role of perfluoropentane in microglia-mediated central inflammatory reactions remains poorly *** this study,we developed perfluoropentane-based oxygen-loaded nanodroplets(PFP-OLNDs)and found that pretreatment with these droplets suppressed the lipopolysaccharide-induced activation of M1-type microglia in vitro and in vivo,and suppressed microglial activation in a mouse model of Parkinson’s *** suppression led to a reduction in the inflammatory response,oxidative stress,and cell migration capacity in ***,the neurotoxic effects were mitigated,which alleviated neuronal ***,ultrahigh-performance liquid chromatography–tandem mass spectrometry showed that the anti-inflammatory effects of PFP-OLNDs mainly resulted from the modulation of microglial metabolic *** further showed that PFP-OLNDs regulated microglial metabolic reprogramming through the AKT-mTOR-HIF-1α***,our findings suggest that the novel PFP-OLNDs constructed in this study alleviate microglia-mediated central inflammatory reactions through metabolic reprogramming.

关键词： metabolic reprogramming microglia microglial migration nanotherapy neurodegenerative diseases neuroinflammation oxygen-loaded nanodroplets Parkinson’s disease perfluoropentane ultra-performance liquid chromatography–mass spectrometry

Measurement of alumina film induced ablation of internal insulator in solid rocket environment

在线全文

学校读者我要写书评

暂无评论

Defence Technology（防务技术） 2023年第11期29卷 181-192页

作者： ji-Yeul Bae In Sik Hwang Yoongoo kang Agency for Defense Development 160488th Bukyuseong-streetDaejeonSouth Korea

This study investigates the ablation of internal insulation induced by the deposition of an alumina film with different lateral film speeds.A sub-scale test solid rocket motor(SRM)was designed in an impinging jet configuration to form an alumina film on the sample and to encourage the lateral movement of the film by a high-speed wall *** static fire tests of the test SRM were conducted with six different jet velocities(V_(jet)=100 m/s,150 m/s,200 m/s,268 m/s,330 m/s,and 450 m/s)that indirectly affected the velocity of the wall jet and the deposition rate of alumina *** ablation velocity was deduced from the difference in the sample thickness after a test using a coordinate measuring *** droplet deposition mass flux and wall jet velocity were obtained via two-phase flow simulation with the same jet velocity and effective *** a result,the characteristics of alumina-induced ablation and the changes in ablation with jet velocities were *** area within0.8×jet diameter was focused upon,where the ratio of ablation velocity to incoming alumina mass was constant for each jet velocity,and showed a similarity in jet *** the ablation velocity was increased from 2.05 to 9.98 mm/s with increasing jet velocity,the ratio of the ablation velocity and alumina mass flux decreased from 1.07×10^(-4)to 0.49×10^(-4)m^(3)/kg as Al_(2)O_(3)-C reactions became less efficient with a reduced residence time of the *** the decrease in residence time by the wall jet is more pronounced for slow reactions involved in Al_(2)O_(3)-C reactions,fast reactions in Al_(2)O_(3)-C reactions are less affected and result in a convergence of the volumetric rate of ablation per unit mass of alumina.

关键词： Internal insulation Solid rocket motor Ablation Alumina