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Nano Research 2022年第9期15卷 8502-8509页

作者： ji Won Yoon Jae-Hyeok Kim young-Moo Jo Jong-Heun lee Department of Materials Science and Engineering Korea UniversitySeoul 02841Republic of Korea

Bimetallic Fe/Ni-based metal-organic frameworks(MOFs)with different Fe/Ni ratios were coated on TiO_(2)nanorods(NRs),and the performances of the heterojunction photoanodes in photoelectrochemical water splitting were *** bandgaps and band positions of the MOFs could be modulated by changing the ratio of the Fe and Ni *** ideal band alignment was achieved between the TiO_(2)NRs and bimetallic MOFs with an optimum ratio of[Fe]/[Ni]=0.25/0.75,which allowed efficient light absorption and charge *** coating of NH_(2)-MIL(Fe)-88 layer on the TiO_(2)NRs decreased the photocurrent density by 33%.In comparison,TiO_(2)/NH_(2)-MIL(Ni)-88 showed a modest improvement in photocurrent density(0.85 mA·cm^(−2)at 1.23 V vs.a reversible hydrogen electrode(RHE)).When bimetallic NH_(2)-MIL(Fe_(0.25)Ni_(0.75))-88 was coated on the TiO_(2)NRs,the photocurrent density reached 1.56 mA·cm^(−2),which was an efficiency enhancement of 3.2 *** mechanism underlying high photoelectrochemical performance was investigated.

关键词： band-structure engineering bimetallic metal-organic frameworks(MOFs) solar water splitting TiO_(2)nanorods NH_(2)-MIL-88

Massive bleeding in small intestinal mucosa-associated lymphoid tissue lymphoma associated with COVID-19 infection:a case report

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Oncology and Translational Medicine 2024年第2期10卷 93-98页

作者： Meiling Huang Xiaowei Wu ji Wang College of Medicine Wuhan University of Science and TechnologyWuhan 430081China Department of Gastroenterology Wuhan Hanyang HospitalWuhan 430050China

The increased risk of mucosa-associated lymphoid tissue(MALT)lymphoma is closely associated with chronic antigenic stimulation,with infection being the most common cause of *** are usually associated with the gastrointestinal tract,and the involvement of small intestinal is *** studies have established a close relationship between novel coronavirus 2019(COVID-19)and the occurrence and progression of various *** article presents a rare case of a small intestinal MALT *** patient was initially admitted with COVID-19 pneumonia and subsequently developed gastrointestinal bleeding during *** and endoscopic treatments were ineffective,and an emergency exploratory laparotomy was *** affected segment of the small intestine was excised,and a pathological biopsy confirmed the diagnosis of MALT *** case underscores the significance of raising clinical awareness of this condition among health care professionals.

关键词： COVID-19 Non-Hodgkin lymphoma Small intestine MALT lymphoma Gastrointestinal hemorrhage Severe pneumonia

Interplay between mesenchymal stem cells and macrophages:Promoting bone tissue repair

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World Journal of Stem Cells 2024年第4期16卷 375-388页

作者： Fei-Fan Zhang Yang Hao Kuai-Xiang Zhang jiang-jia Yang Zhi-Qiang Zhao Hong-jian Liu ji-Tian Li Molecular Biology Lab Henan Luoyang Orthopedic Hospital(Henan Provincial Orthopedic Hospital)Zhengzhou 450000Henan ProvinceChina Graduate School Hunan University of Chinese MedicineChangsha 410208Hunan ProvinceChina Graduate School Henan University of Chinese MedicineZhengzhou 450046Henan ProvinceChina Department of Orthopaedics The First Affiliated Hospital of Zhengzhou UniversityZhengzhou 450052Henan ProvinceChina

The repair of bone tissue damage is a complex process that is well-orchestrated in time and space,a focus and difficulty in orthopedic *** recent years,the success of mesenchymal stem cells(MSCs)-mediated bone repair in clinical trials of large-area bone defects and bone necrosis has made it a candidate in bone tissue repair engineering and regenerative *** are closely related to *** one hand,MSCs regulate the immune regulatory function by influencing macrophages proliferation,infiltration,and phenotype polarization,while also affecting the osteoclasts differentiation of *** the other hand,macrophages activate MSCs and mediate the multilineage differentiation of MSCs by regulating the immune *** cross-talk between MSCs and macrophages plays a crucial role in regulating the immune system and in promoting tissue *** full use of the relationship between MSCs and macrophages will enhance the efficacy of MSCs therapy in bone tissue repair,and will also provide a reference for further application of MSCs in other diseases.

关键词： Bone tissue damage Inflammation Macrophages Mesenchymal stem cells Tissue regeneration

Multimodal Omics Approaches to Aging and Age‑Related Diseases

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Phenomics 2024年第1期4卷 56-71页

作者： Qianzhao ji Xiaoyu jiang Minxian Wang Zijuan Xin Weiqi Zhang jing Qu Guang‑Hui Liu State Key Laboratory of Membrane Biology Instituteof ZoologyChinese Academy of SciencesBeijing 100101China State Key Laboratory of Stem Cell and ReproductiveBiology Institute of ZoologyChinese Academy of SciencesBeijing 100101China Key Laboratory of Organ Regeneration and Reconstruction Institute of ZoologyChinese Academy of SciencesBeijing 100101China CAS Key Laboratory of Genomic and Precision Medicine Beijing Institute of GenomicsChinese Academyof Sciences and China National Center for BioinformationBeijing 100101China University of Chinese Academy of Sciences Beijing 100049China Institute for Stem Cell and Regeneration Chinese Academyof SciencesBeijing 100101China Beijing Institute for Stem Cell and Regenerative Medicine Beijing 100101China School of Future Technology University of ChineseAcademy of SciencesBeijing 100190China Advanced Innovation Center for Human Brain Protection National Clinical Research Center for GeriatricDisordersXuanwu Hospital Capital Medical UniversityBeijing 100053China Aging Translational Medicine Center International Centerfor Aging and CancerXuanwu HospitalCapital MedicalUniversityBeijing 100053China

Aging is associated with a progressive decline in physiological capacities and an increased risk of aging-associated *** increasing body of experimental evidence shows that aging is a complex biological process coordinately regulated by multiple factors at diferent molecular ***,it is difcult to delineate the overall systematic aging changes based on single-layer ***,multimodal omics approaches,in which data are acquired and analyzed using complementary omics technologies,such as genomics,transcriptomics,and epigenomics,are needed for gaining insights into the precise molecular regulatory mechanisms that trigger *** recent years,multimodal omics sequencing technologies that can reveal complex regulatory networks and specifc phenotypic changes have been developed and widely applied to decode aging and age-related *** review summarizes the classifcation and progress of multimodal omics approaches,as well as the rapidly growing number of articles reporting on their application in the feld of aging research,and outlines new developments in the clinical treatment of age-related diseases based on omics technologies.

关键词： Multimodal omics approaches Aging Genome Epigenome

Anti-Jamming Null Space Projection Beamforming Based on Symbiotic Radio

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工程与科学中的计算机建模(英文) 2024年第1期138卷 679-689页

作者： Baofeng ji Yifan Liu Tingpeng Li Ling Xing Weixing Wang Shahid Mumtaz Xiaolong Shang Wanying Liu Congzheng Han State Key Laboratory of Complex Electromagnetic Environment Effects on Electronics and Information System(CEMEE) Luoyang471000China Research and Innovation Center of Intelligent System Longmen LaboratoryLuoyang471000China College of Information Engineering Henan University of Science and TechnologyLuoyang471000China Institute of Atmospheric Physics Chinese Academy of Sciences(LAGEO)Beijing100000China Instituto de Telecomunicaes Aveiro3800-005Portugal Chinese Academy of Agricultural Mechanization Sciences Beijing100000China

With the development of information technology,more and more devices are connected to the Internet through wireless communication to complete data *** to the broadcast characteristics ofwireless channels,wireless networks have suffered more and more malicious *** layer security has received extensive attention from industry and *** is considered to be one of the most important technologies related to physical layer *** beamforming technology,messages can be transmitted to legitimate users in an offset direction that is as orthogonal as possible to the interference channel to ensure the reception SINR by legitimate *** the symbiotic radio(SR)technology,this paper considers a symbiotic radio antijamming MIMO system equipped with a multi-antenna system at the main base *** order to avoid the interference signal and improve the SINR of the signal received by the *** base station is equipped with a uniform rectangular antenna array,and using Null Space Projection(NSP)Beamforming,Intelligent Reflecting Surface(IRS)can assist in changing the beam’s *** simulation results show that NSP Beamforming could make a better use of the null space of interference,which can effectively improve the received SINR of users under directional interference,and improve the utilization efficiency of signal energy.

关键词： Symbiotic radio anti-jamming MIMO NSP Beamforming physical layer security

Jacobsen syndrome with bilateral periventricular white matter lesions

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World Journal of Pediatrics 2022年第2期18卷 142-143页

作者： Hyun-Joo lee Hae-ln lee ji-Hoon Na young-Mock lee Department of Pediatrics Yonsei University College of MedicineSeoulKorea Department of Pediatrics Gangnam Severance HospitalYonsei University College of Medicine21Eonju-roGangnam-guSeoul 06273Korea

A 2-month-old girl presented facial dimorphism,including frontal bossing,hypertelorism,a broad nasal bridge,low-set ears,hypotonia with mild spasticity,and mild *** head circumference was 40.8 cm(75-90 percentile).The... 详细信息

关键词： white ism Jacobsen

Controlling hydrogenation of C=C and C=O bonds in cinnamaldehyde using Pt_(1)/Ni and Pt_(1)/Co single-atom alloy catalysts

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Rare Metals 2024年第6期43卷 2859-2868页

作者： Huan-Shi Lan Yi-Da Yang Qing-Di Sun Hao Zhang Ying Zhang Qian He Ran Chen Guo-Yi Bai Xiao-Hui He Hong-Bing ji School of Chemistry and Chemical Engineering Guangxi UniversityNanning 530004China Key Laboratory of Bioinorganicand Synthetic Chemistry of Ministry of Education Fine Chemical Industry Research InstituteSchool of ChemistryIGCMESun Yat-sen UniversityGuangzhou510275China UBFC CNRSENSMMFEMTO-ST Institute25030 Besancon CEDEXFrance College of Chemistry and Materials Science Hebei UniversityBaoding 071002China State Key Laboratory Breeding Base of Green-Chemical Synthesis Technology Institute of Green Petroleum Processing and Light Hydrocarbon ConversionCollege of Chemical EngineeringZhejiang University of TechnologyHangzhou 310014China

Selective hydrogenation of C=C and C=O bonds in cinnamaldehyde(CAL)to produce desired products is a challenging task due to the complex conjugate system of the two unsaturated functional *** this study,a simple ball milling method is presented for synthesizing Pt-based single-atom alloy catalysts(SAAs)that can function as a control switch for the selective hydrogenation of CAL into highly valuable products.

关键词： alloy hydrogenation conjugate

LA-D-B1,a novel Abemaciclib derivative,exerts anti-breast cancer effects through CDK4/6

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BIOCELL 2024年第5期48卷 847-860页

作者： LING MA ZIRUI jiANG XIAO HOU YUTING XU ZIYUN CHEN SIYI ZHANG HANXUE LI SHAOjiE MA GENG ZHANG XIUJUN WANG jiNG ji jiangsu Key Laboratory of Marine Pharmaceutical Compound Screening College of PharmacyJiangsu Ocean UniversityLianyungang222000China School of Medicine Xiamen UniversityXiamen361102China

Background:Regulatory proteins involved in human cellular division and proliferation,cyclin-dependent kinases 4 and 6(CDK4/6)are overexpressed in numerous cancers,including triple-negative breast cancer(TNBC).TNBC is a common pathological subtype of breast cancer that is prone to recurrence and metastasis,and has a single treatment *** one of the CDK4/6 inhibitors,abemaciclib can effectively inhibit the growth of breast *** this study,we synthesized LA-D-B1,a derivative of Abemaciclib,and investigated its anti-tumor effects in breast ***:Cellular viability was assessed using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide(MTT)*** cloning and migration abilities were determined by colony formation assay and wound healing *** invasion abilities and adhesion were determined by cell invasion assay and cell adhesion *** impact of compound LA-D-B1 on cell proliferation and the cell cycle was analyzed through Western blotting,which quantified the levels of proteins associated with the cyclin-dependent kinase(CDK)4/6-cyclin D-Rb-E2F *** in vivo anti-tumor activity of compound LA-D-B1 was investigated using a chick chorioallantoic membrane(CAM)***:The study demonstrated that LA-D-B1 effectively suppressed breast cancer cell proliferation,induced apoptosis,and caused cell cycle ***,LA-D-B1 reduced the expression of key proteins in the CDK4/6-cyclin D-Rb-E2F pathway,including CDK4,CDK6 and *** results also indicated significant antitumor activity of LA-D-B1 in a transplanted tumor ***:In this study,LA-D-B1 demonstrated a potent anti-tumor effect by effectively suppressing cell proliferation and inhibiting cell cycle progression in breast *** findings highlight the potential of LA-D-B1 as a valuable compound for enhancing therapeutic outcomes and controlling the progression of breast cancer.

关键词： CDK4/6 inhibitor Breast cancer Antitumor activity Cell cycle

Activity promotion of RhCa/AlOsingle-atom catalyst in1-octene hydroformylation: a volcano curve exists between Ca adding ratio and catalytic activity

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Science China Chemistry 2024年

作者： Hao Zhang Xingcong Zhang Xilun Wang Qingdi Sun Hao Liu Hongbing ji Xiaohui He Huizhou Research Institute Sun Yat-sen University Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education Fine Chemical Industry Research Institute School of Chemistry IGCME Sun Yat-sen University State Key Laboratory Breeding Base of Green-Chemical Synthesis Technology Institute of Green Petroleum Processing and Light Hydrocarbon Conversion College of Chemical Engineering Zhejiang University of Technology

Single-atom catalysts(SACs) are considered the best candidates for olefin hydroformylation due to their combined advantages of homogeneous and heterogeneous catalysts. Unlike conventional organo-phosphine modification, Rh SAC is modified by introducing Ca, resulting in a significant increase in activity(maximum ～5.7-fold) and stability. Furthermore, a volcano curve between Ca addition ratio and catalytic activity is found. Introducing Ca significantly increases activity by decreasing the energy barrier, but excessive Ca decreases activity due to hindering substrate adsorption and reaction.

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MicroRNA miR-252-5p regulates the Notch signaling pathway by targeting Rab6 in Drosophila wing development

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Insect Science 2023年第5期30卷 1431-1444页

作者： Do-Hwan Lim Min-Seok Choi ji Won Jeon young Sik lee School of Systems Biomedical Science Soongsil UniversitySeoulRepublic of Korea College of Life Sciences and Biotechnology Korea UniversitySeoulRepublic of Korea Institute of Animal Molecular Biotechnology Korea UniversitySeoulRepublic of Korea

The Notch signaling pathway plays a central role in the development of various ***,dysregulation of microRNAs(miRNAs),which are crucial regulators of gene expression,can disrupt signaling pathways at all stages of *** Notch signaling is involved in wing development in Drosophila,the mechanism underlying miRNA-based regulation of the Notch signaling pathway is ***,we report that loss of Drosophila miR-252 increases the size of adult wings,whereas the overexpression of miR-252 in specific compartments of larval wing discs leads to patterning defects in the adult *** miR-252 overexpression-induced wing phenotypes were caused by aberrant Notch signaling with intracellular accumulation of the full-length Notch receptor during development,which could be due to defects in intracellular Notch trafficking associated with its recycling to the plasma membrane and autophagy-mediated ***,we identified Rab6 as a direct target of miR-252-5p;Rab6 encodes a small Ras-like GTPase that regulates endosomal trafficking *** with this finding,RNAi-mediated downregulation of Rab6 led to similar defects in both wing patterning and Notch ***,co-overexpression of Rab6 completely rescued the wing phenotype associated with miR-252 overexpression,further supporting that Rab6 is a biologically relevant target of miR-252-5p in the context of wing ***,our data indicate that the miR-252-5p-Rab6 regulatory axis is involved in Drosophila wing development by controlling the Notch signaling pathway.

关键词： Drosophila miR-252-5p Notch signaling Rab6 wing development