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Liver inflammatory pseudotumor or parasitic granuloma?

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World Journal of Gastroenterology 2000年第3期6卷 458-460页

作者： ji xl Shen MS Yin T Gen Hosp Chinese PLA Dept Pathol Beijing 100853 Peoples R China

INTRODUCTION Liver pseudotumor is a very rare benign *** the first case reported by Pack and Baker in1953,only 40 cases had been reported up to *** diagnostic challenge of hepatic inflammatorypseudotumor is emphasized... 详细信息

关键词： inflammatory pseudotumor parasitic granuloma ascariasis larva liver disease

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肝脏病变的细针穿剌细胞学检查

世界华人消化杂志 1999年第6期7卷 467-468页

作者：纪小龙解放军总医院病理科

近２０ａ以来，虽然Ｂ超，ＣＴ和磁共振广泛地应用于肝脏疾病的诊断，但肝占位性病变仅依靠影象学检查仍无法作出定性的诊断．国外自２０世纪７０年代起，Ｂ超和细针穿剌结合起来诊治肝脏疾病，国内８０年代开始Ｂ超引导下细针穿剌诊断... 详细信息

近２０ａ以来，虽然Ｂ超，ＣＴ和磁共振广泛地应用于肝脏疾病的诊断，但肝占位性病变仅依靠影象学检查仍无法作出定性的诊断．国外自２０世纪７０年代起，Ｂ超和细针穿剌结合起来诊治肝脏疾病，国内８０年代开始Ｂ超引导下细针穿剌诊断肝脏占位性病变．良恶性鉴别诊断准确...

关键词：肝疾病诊断肝肿瘤活组织检查针吸

Is there a "chain-foldability" effect without neighboring moiety-assistance?

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Chinese Journal of Chemistry 1997年第2期15卷 174-177页

作者： ji, GZ Cui, xl Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China [*]Shanghai Institute of Organic Chemistry Chinese Academy of Sciences Shanghai 200032 China

The coaggregating tendencies of five methyl esters of saturated or unsaturated single-chain carboxylic acids, namely octanoic (8-Me), dodecanoic (12-Me), stearic (18-Me), oleic (c18:1-Me) and elaidic (t-18:1-Me) acids, were investigated in five aquiorgano binary solvent systems, V/V DX-H2O (Phi=0.50, 0.45, 0.40, 0.30, 0.20), using naphthylethyl octyl (Np-8), dodecyl (Np-12), hexadecyl (Np-16) ether as fluorescent probes. The orders of their coaggregating tendencies changed in solvents of different Phi values. Our results could be rationalized by a chain-foldability effect without neighboring moiety participation.

关键词： chain-foldability effect coaggregation fluorescence

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东莨菪碱与苯扎氯铵干眼症大鼠造模方法研究

动物医学进展 2017年第10期38卷 43-50页

作者：杨延婷张丹吴丽洁李志元张霁贾一凡马晓芃上海中医药大学上海210203 上海市针灸经络研究所上海200030 北京中医药大学北京100001

为比较氢溴酸东莨菪碱皮下注射与苯扎氯铵滴眼制作干眼症动物模型的各自特点,将健康SD大鼠随机分为正常组、东莨菪碱加风组、苯扎氯铵组和吹风对照组。正常组不接受任何处理;东莨菪碱组皮下注射氢溴酸东莨菪碱注射剂;苯扎氯铵组以2mg/m... 详细信息

为比较氢溴酸东莨菪碱皮下注射与苯扎氯铵滴眼制作干眼症动物模型的各自特点,将健康SD大鼠随机分为正常组、东莨菪碱加风组、苯扎氯铵组和吹风对照组。正常组不接受任何处理;东莨菪碱组皮下注射氢溴酸东莨菪碱注射剂;苯扎氯铵组以2mg/mL苯扎氯铵滴眼液每日3次滴眼;吹风组仅置于吹风装置中每日12h。于试验第3、7、10天检查Schirmer I试验(SIT)、泪膜破裂时间(BUT)、角膜荧光素染色(FLS)。结果表明,东莨菪碱组在第3、7、10天,SIT与正常组相比具有显著差异(P<0.05),第7、10天BUT和FLS与正常组相比具有显著差异(P<0.05);苯扎氯铵组在试验第7、10天,SIT试验和BUT与正常组相比有显著差异(P<0.05),BUT第10天差异达到最大,在第3、7、10天,FLS与正常组相比具有显著差异(P<0.05);组织病理学检查东莨菪碱组泪腺较苯扎氯铵组明显有腺上皮细胞萎缩;苯扎氯铵组大鼠角结膜上皮细胞明显变薄,表层细胞排列紊乱,细胞数量显著减少,并存在炎性细胞浸润。提示造模10d氢溴酸东莨菪碱注射剂皮下注射配合吹风制作的干眼症动物模型对大鼠泪腺及眼表上皮细胞影响显著,伴有较轻程度的眼表损伤,更适合早期轻中度干眼造模;苯扎氯铵滴眼造模方法易造成眼表上皮损伤,适合短期重度干眼的造模。

关键词：干眼症造模方法东莨菪碱苯扎氯铵大鼠

A vascular endothelial growth factor–loaded chitosan-hyaluronic acid hydrogel scaffold enhances the therapeutic effect of adipose-derived stem cells in the context of stroke

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Neural Regeneration Research 2025年第12期20卷 3591-3605页

作者： Zhijian Zheng Xiaohui Lin Zijun Zhao Qiang Lin ji Liu Manli Chen Wenwen Wu Zhiyun Wu Nan Liu Hongbin Chen Department of Neurology Fujian Medical University Union HospitalFuzhouFujian ProvinceChina Department of Rehabilitation Fujian Medical University Union HospitalFuzhouFujian ProvinceChina Fujian Key Laboratory of Molecular Neurology Fujian Medical UniversityFuzhouFujian ProvinceChina Institute of Clinical Neurology Fujian Medical UniversityFuzhouFujian ProvinceChina

Adipose-derived stem cell,one type of mesenchymal stem cells,is a promising approach in treating ischemia-reperfusion injury caused by occlusion of the middle cerebral ***,its application has been limited by the complexities of the ischemic *** scaffolds,which are composed of hyaluronic acid and chitosan,exhibit excellent biocompatibility and biodegradability,making them promising candidates as cell *** endothelial growth factor is a crucial regulatory factor for stem *** hyaluronic acid and chitosan have the potential to make the microenvironment more hospitable to transplanted stem cells,thereby enhancing the therapeutic effect of mesenchymal stem cell transplantation in the context of ***,we found that vascular endothelial growth factor significantly improved the activity and paracrine function of adipose-derived stem ***,we developed a chitosan-hyaluronic acid hydrogel scaffold that incorporated vascular endothelial growth factor and first injected the scaffold into an animal model of cerebral ischemiareperfusion *** loaded with adipose-derived stem cells,this vascular endothelial growth factor–loaded scaffold markedly reduced neuronal apoptosis caused by oxygen-glucose deprivation/reoxygenation and substantially restored mitochondrial membrane potential and axon *** in vivo experiments revealed that this vascular endothelial growth factor–loaded hydrogel scaffold facilitated the transplantation of adipose-derived stem cells,leading to a reduction in infarct volume and neuronal apoptosis in a rat model of stroke induced by transient middle cerebral artery *** also helped maintain mitochondrial integrity and axonal morphology,greatly improving rat motor function and ***,utilizing a hydrogel scaffold loaded with vascular endothelial growth factor as a stem cell delivery system can mitigate the adverse effects of ischemic microenvironment

关键词： adipose-derived stem cells chitosan hyaluronic acid hydrogel ischemia-reperfusion oxygen-glucose deprivation/reoxygenation stroke transient middle cerebral artery occlusion transplantation vascular endothelial growth factor

STUDIES ON THE SAPONIN CONSTITUENTS OF GYNOSTEMMA LONGIPES

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Chinese Chemical Letters 1991年第3期2卷 221-222页

作者： Xiao Li ZHANG Heng Li ZHANG Wen ji SUN Zhen Fang SHAN National North-West Center of Metrology,xl＇AN,710048 SHAANXI Provincial Institute for Drug Control,xl＇AN,710061

Two new cornpounds,saponin I and saponin II,were isolated from Gynostemma longipes ***. The struetures have been characterized on the basis of cbenical and speetroseopie evidence. ^-~.

关键词： CHO IR STUDIES ON THE SAPONIN CONSTITUENTS OF GYNOSTEMMA LONGIPES

Effect of driving cycles on energy efficiency of electric vehicles

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Science China(Technological Sciences) 2009年第11期52卷 3168-3172页

作者： ji FenZhu XU LiCong WU ZhiXin School of Transportation Science and Engineering Beihang UniversityBeijing 100191China Tianjin Qingyuan Electric Vehicle Co. LtdTianjin 300162China

Based on several typical domestic and foreign driving cycles, the energy usage efficiency of the EVs-xl 2000 type electric vehicle (EV) is analyzed. The energy usage efficiency of EVs and the evaluation index of electromotor efficiency are studied. The concepts of "interval usage percentage of energy efficiency" and "exertion degree of energy efficiency" of electromotor are presented. The effects of driving cycles on the distribution of the running status of electromotor and the efficiency are investi-gated. The efficiency of electromotor and the trend of average driving force at different driving cycles are discussed. The exertion degree of energy efficiency and the total power train efficiency of the EVs-xl 2000 type electric vehicle at typical driving cycles are analyzed and calculated. The result indicates that the driving cycle engenders a big influence on the exertion degree of electromotor energy efficiency at different driving cycles. Dissimilar driving cycles result in different efficiency distributions of electromotor, the control system as well as the average driving force and driving range are variable.

关键词： electric vehicles electromotor driving cycle energy efficiency evaluation index

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溃疡性结肠炎治疗目标的现状与挑战

中华消化杂志 2022年第2期42卷 141-144页

作者：季强牛巍巍张晓岚河北医科大学第二医院消化内科石家庄050000

溃疡性结肠炎是一种慢性非特异性肠道炎症性疾病,可能与遗传、环境、微生物和免疫等多种因素密切相关。随着生物技术的进步和多种新型生物制剂的问世,溃疡性结肠炎的治疗效果正在逐年改善,其治疗目标已经从临床缓解逐渐演变为内镜缓解... 详细信息

溃疡性结肠炎是一种慢性非特异性肠道炎症性疾病,可能与遗传、环境、微生物和免疫等多种因素密切相关。随着生物技术的进步和多种新型生物制剂的问世,溃疡性结肠炎的治疗效果正在逐年改善,其治疗目标已经从临床缓解逐渐演变为内镜缓解甚至组织学缓解。本文主要介绍溃疡性结肠炎治疗目标的现状和挑战。

关键词：结肠炎溃疡性治疗目标缓解现状挑战

Excavation-induced microseismicity: microseismic monitoring and numerical simulation

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2012年第6期13卷 445-460页

作者： Nu-wen XU Chun-an TANG Hong LI Feng DAI Ke MA jing-dong SHAO ji-chang WU State Key Laboratory of Hydraulics and Mountain River Engineering College of Water Resources and Hydropower Siehuan UniversityChengdu 610065China Institute o fRock Instability and Seismicity Research Dalian University of TechnologyDalian 116024China HydroChina Chengdu Engineering Corporation Chengdu 610072China China Guodian Dadu River Dagangshan Hydropower Development Co. Ltd.Ya'an 625409China

The volume of influence of excavation at the right bank slope of Dagangshan Hydropower Station, southwest China, is essentially determined from microseismic monitoring, numerical modeling and conventional measurements as well as in situ observations. Microseismic monitoring is a new application technique for investigating microcrackings in rock slopes. A micro- seismic monitoring network has been systematically used to monitor rock masses unloading relaxation due to continuous exca- vation of rock slope and stress redistribution caused by dam impoundment later on, and to identify and delineate the potential slippage regions since May, 2010. An important database of seismic source locations is available. The analysis of microseismic events showed a particular tempo-spatial distribution. Seismic events predominantly occurred around the upstream slope of 1180 m elevation, especially focusing on the hanging wall of fault xl316-1. Such phenomenon was interpreted by numerical modeling using RFPA-SRM code （realistic failure process analysis-strength reduction method）. By comparing microseismic activity and results of numerical simulation with in site observation and conventional measurements results, a strong correlation can he obtained between seismic source locations and excavation-induced stress distribution in the working areas. The volume of influence of the rock slope is thus determined. Engineering practices show microseismic monitoring can accurately diagnose magnitude, intensity and associated tempo-spatial characteristics of tectonic activities such as faults and unloading zones. The integrated technique combining seismic monitoring with numerical modeling, as well as in site observation and conventional surveying, leads to a better understanding of the internal effect and relationship between microseismic activity and stress field in the right bank slope from different perspectives.

关键词： Microseismic monitoring Rock slope Numerical simulation Stability analysis Dagangshan Hydropower Station