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Endogenous Trypsin Triggers Free Fluoride Release from Antarctic Krill(Euphausia superba)Cuticle

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Journal of Ocean University of China 2024年第3期23卷 766-774页

作者： PENG Yuanhuai ji wei ji Hongwu HAN Zhiping ZHANG Shiqi WEN Yaping College of Food Science and Engineering Lingnan Normal UniversityZhanjiang 524048China College of Biological and Food Engineering Guangdong University of EducationGuangzhou 510303China Guangdong Provincial Key Laboratory of Aquatic Products Processing and Safety Guangdong Ocean UniversityZhanjiang 524088China College of Food Science and Technology Guangdong Ocean UniversityZhanjiang 524088China College of Continuing Education Lingnan Normal UniversityZhanjiang 524048China

During postmortem storage,fluoride in Antarctic krill can be enriched in the ***,as the most important digestive enzyme in Antarctic krill with a high activity in low temperature,plays a potential role in this *** this study,endogenous trypsin was purified and its properties were *** involvement of trypsin in the generation of free fluoride from Antarctic krill cuticle was *** microstructure before and after hydrolysis was compared with scanning electron microscopy,and the ash samples of the hydrolyzed Antarctic krill cuticle were analyzed with X-ray diffraction,Fourier transform infrared spectroscopy,and electron dispersive spectroscopy,*** spectrometry analysis and inhibition tests confirmed that the purified enzyme was endogenous *** of the present study indicated that trypsin digestion caused the increases of the concentrations of both fluoride ions and free amino N simultaneously,while the protein coated on the cuticle surface was dissolved ***,no compositional change was detected in the cuticle inorganic *** findings suggest that trypsin triggered free fluoride release from Antarctic krill *** addition,the kinetics of free fluoride release could be described by the equation C_(W)=(1-0.97^(-0.006t)-0.03e^(0.0558t))×337.53+*** present study improved the understanding of the role of trypsin in free fluoride release from Antarctic krill cuticle,facilitating future studies aimed at reducing the fluoride content in krill protein during Antarctic krill processing.

关键词： Antarctic krill cuticle fluoride trypsin

Segment Anything Is Not Always Perfect: An Investigation of SAM on Different Real-world Applications

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Machine Intelligence Research 2024年第4期21卷 617-630页

作者： wei ji jingjing Li Qi Bi Tingwei Liu Wenbo Li Li Cheng University of Alberta Edmonton T6G 2R3Canada Wuhan University Wuhan 430072China Dalian University of Technology Dalian 116024China Samsung Research America Mountain View 94043USA

Recently,Meta AI Research approaches a general,promptable segment anything model(SAM)pre-trained on an unprecedentedly large segmentation dataset(SA-1B).Without a doubt,the emergence of SAM will yield significant benefits for a wide array of practical image segmentation *** this study,we conduct a series of intriguing investigations into the performance of SAM across various applications,particularly in the fields of natural images,agriculture,manufacturing,remote sensing and *** analyze and discuss the benefits and limitations of SAM,while also presenting an outlook on its future development in segmentation *** doing so,we aim to give a comprehensive understanding of SAM's practical *** work is expected to provide insights that facilitate future research activities toward generic *** code is publicly available at https://***/LiuTingWed/SAM-Not-Perfect.

关键词： Segment anything model(SAM) visual perception segmentation foundational model computer vision.

Defects in the grain interiors of 3 mol%yttria-stabilized tetragonal zirconia polycrystal ceramics with 0.25 wt%alumina

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Journal of Advanced Ceramics 2024年第4期13卷 469-477页

作者： Yan Xiong Lian Luo Yao Cheng Zhi Liu Qi Liu weimin Wang wei ji School of Materials&Chemical Engineering Hubei Province Key Laboratory of Green Materials for Light IndustryHubei University of TechnologyWuhan 430068China Fujian Institute of Research on the Structure of Mater Chinese Academy of SciencesFuzhou 350002China jiangxi Provincial Engineering Research Center for Multifunction Zirconia Materials Jiangxi Size Materials Co.Ltd.Jiujiang 332500China State Key Laboratory of Advance Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China

The presence of high-density defects is rarely observed in bulk 3 mol%yttria-stabilized tetragonal zirconia polycrystal(3Y-TZP)ceramics obtained through conventional pressureless *** the present work,fine-grained dense 147 nm 3Y-TZP ceramics were prepared by pressureless sintering of commercial 0.25 wt%alumina-doped zirconia powders at 1300℃.A novel discovery was reported in which large amounts of defects were present in the grain interiors of the *** phenomenon was further examined using three types of powder samples,and the reasons for defect formation were investigated by microstructural characterization using high-resolution transmission electron microscopy(HRTEM)analysis and Rietveld *** results confirmed the essential dependence of the defect formation on the alumina *** authors attributed the defect formation to the significant difference in ionic radii of the solvent and solute during the dissolution of alumina into the zirconia *** sintering kinetics were proposed to be enhanced by the presence of substantial defects,which consequently favored the low-temperature sintering of the alumina-doped zirconia ceramics.

关键词： 3 mol%yttria-stabilized tetragonal zirconia polycrystal(3Y-TzP)ceramics alumina addition microstructure defect

Optimum process conditions for preparation of Cu-en/AP composite microspheres by electrostatic spray method based on ANSYS(Fluent) simulation

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火炸药学报 2024年

作者： Lei Liu TianYuan Hu MingJun Song wei ji National Academy of Defense Technology Southwest University of Science and Technology 201 Research Institute Sixth Research Institute of China Aerospace Science and Industry Corporation

This study employed ANSYS (Fluent) to set up an orthogonal experimental design for simulating the preparation of AP/Cu-en composite microspheres via the electrostatic spray method. Additionally， a controlled variable approach was used to simulate the influence of flow rate， solvent ratio， and solid mass on the experimental results. The purpose is to study the optimal process conditions for preparing Cu-en/AP composite microspheres through electrostatic spray and to reveal the effects of changes in droplet properties and flow rate during the electrostatic spray process on the experimental *** results indicate that under the following process conditions: a flow rate of 2.67e-3 kg/s， acetone to deionized water ratio of 1.5:1， and a solid mass of 200 mg， the theoretical diameter of the composite microspheres can reach the nanoscale. These microspheres exhibit high velocity within the electric field， there was no significant deviation in the motion trajectory. The particle diameter decreases with the increase of *** the process，This decreasing trend begins to moderate when the flow rate is 1e-3kg/s. When increasing the solvent ratio (higher acetone content)，at the begging，the particle diameter is reduced， followed by an increase. An increase in solid mass also leads to reduced in particle diameter. At a solid mass of approximately 220 mg， the particle diameter starts to increase linearly. It will be explained in detail in this paper.

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Cloud-Model-Based Feature Engineering to Analyze the Energy-Water Nexus of a Full-Scale Wastewater Treatment Plant

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Engineering 2024年第5期36卷 63-75页

作者： Shan-Shan Yang Xin-Lei Yu Chen-Hao Cui jie Ding Lei He wei Dai Han-Jun Sun Shun-Wen Bai Yu Tao ji-wei Pang Nan-Qi Ren State Key Laboratory of Urban Water Resource and Environment Harbin Institute of TechnologyHarbin 150000China Key Laboratory of Environmental Biotechnology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China School of Civil and Environmental Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China China Energy Conservation and Environmental Protection Group Beijing 100089China

Wastewater treatment plants(WWTPs)are important and energy-intensive municipal *** energy consumption and relatively low operating performance are major challenges from the perspective of carbon ***,water-energy nexus analysis and models for WWTPs have rarely been reported to *** this study,a cloud-model-based energy consumption analysis(CMECA)of a WWTP was conducted to explore the relationship between influent and energy consumption by clustering its influent’s *** principal component analysis(PCA)and K-means clustering were applied to classify the influent condition using water quality and volume *** energy consumption of the WWTP is divided into five standard evaluation levels,and its cloud digital characteristics(CDCs)were extracted according to bilateral constraints and golden ratio *** results showed that the energy consumption distribution gradually dispersed and deviated from the Gaussian distribution with decreased water concentration and *** days with high energy efficiency were extracted via the clustering method from the influent category of excessive energy consumption,represented by a compact-type energy consumption distribution curve to identify the influent conditions that affect the steady distribution of energy *** local WWTP has high energy consumption with 0.3613 kW·h·m^(-3)despite low influent concentration and volumes,across four consumption levels from low(I)to relatively high(IV),showing an unsatisfactory operation and management *** average oxygenation capacity,internal reflux ratio,and external reflux ratio during high energy efficiency days recognized by further clustering were obtained(0.2924-0.3703 kg O_(2)·m^(-3),1.9576-2.4787,and 0.6603-0.8361,respectively),which could be used as a guide for the days with low energy ***,this study offers a water-energy nexus analysis method to identify influent conditions with operational manageme

关键词： Wastewater treatment plants Cloud-model theory Data mining Principal component analysis K-means clustering Cloud-model-based energy consumption analysis

Trusted detection for Parkinson’s disease based on uncertainty estimation

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The Journal of China Universities of Posts and Telecommunications 2024年

作者： Zhou Lin Li Yun ji wei Liu Yuxuan Zheng Huifen School of Computer Science Nanjing University of Posts and Telecommunications School of Communications and Information Engineering Nanjing University of Posts and Telecommunications Bell Honors School Nanjing University of Posts and Telecommunications Affiliated Geriatric Hospital of Nanjing Medical University

Currently， most deep learning methods used for Parkinson’s disease (PD) detection lack reliability assessment. This characteristic makes erroneous results difficult to be identified in practice， leading to potentially serious consequences. To address this issue， prior network with the distance measure layer (PNDM) was proposed in this paper. PNDM consists of two modules: prior network (PN) and the distance measure (DM) layer. The prior network is employed to estimate data uncertainty， and the DM layer is utilized to estimate model uncertainty. The goal of this work is to provide accurate and reliable PD detection through uncertainty estimation. Experiments show that PNDM can effectively estimate both model uncertainty and data uncertainty， rendering it more suitable for uncertainty estimation in PD detection compared to existing methods.

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波形钢腹板梁T形接头焊接仿真分析与试验研究

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哈尔滨工程大学学报 2024年第4期45卷 691-698页

作者：冀伟张鹏湖南大学土木工程学院湖南长沙410082 兰州交通大学土木工程学院甘肃兰州730070

为了解决波形钢腹板梁焊接温度场和残余应力分布尚不明确的问题,本文基于Simufact Welding软件建立三维有限元模型,对其T形接头的焊接温度场和残余应力进行了预测,并对模拟结果进行了试验验证。波形钢腹板梁的焊接温度场分布与熔池中心... 详细信息

为了解决波形钢腹板梁焊接温度场和残余应力分布尚不明确的问题,本文基于Simufact Welding软件建立三维有限元模型,对其T形接头的焊接温度场和残余应力进行了预测,并对模拟结果进行了试验验证。波形钢腹板梁的焊接温度场分布与熔池中心距离有关,距离熔池中心越近,温度梯度越大;焊接残余应力以纵向残余拉应力为主,而横向残余应力的应力水平相对较低,拉压应力共存;焊接速度和底板厚度的改变只会影响残余应力的峰值大小,不会影响残余应力的分布规律。结果表明:数值模拟结果和试验实测值吻合良好,数值模拟可靠。

关键词：桥梁工程波形钢腹板梁 T形接头焊接温度场焊接残余应力参数分析焊接速度腹板厚度

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波形钢腹板梁焊接残余应力分布及试验验证

西南交通大学学报 2024年第2期59卷 289-297页

作者：冀伟刘勇湖南大学土木工程学院湖南长沙410082 兰州交通大学土木工程学院甘肃兰州730070

为研究波形钢腹板梁焊接残余应力的分布规律,通过有限元软件建立其三维热弹塑性模型,利用热-力耦合分析技术对其焊接温度场和应力场进行有限元数值仿真,采用双椭球体热源和修改单元材料属性的方法实现能量输入和焊缝填充,并将模拟计算... 详细信息

为研究波形钢腹板梁焊接残余应力的分布规律,通过有限元软件建立其三维热弹塑性模型,利用热-力耦合分析技术对其焊接温度场和应力场进行有限元数值仿真,采用双椭球体热源和修改单元材料属性的方法实现能量输入和焊缝填充,并将模拟计算结果与实测值进行对比分析.结果表明:有限元预测的波形钢腹板梁残余应力分布与实测结果具有相同趋势,在波形钢腹板梁焊缝的弯折角处,残余应力发生一定幅度的连续应力波动;底板和腹板的残余应力峰值均出现在焊缝中心区域,其值分别为材料屈服强度的1.30倍和1.26倍;底板纵向残余拉应力在焊缝中心线两侧78 mm范围内急速下降后缓慢过渡为压应力,在底板较窄一侧压应力线性增大,最大值约为材料屈服强度的0.61倍;在底板较宽一侧压应力线性减小,并在边缘处转化为拉应力;焊接速度对残余应力分布扰动不大,而对残余应力峰值影响较显著;当焊接速度从150 mm/min增加至250 mm/min时,横向和纵向的残余应力最大值分别增加了27.11%和5.88%.

关键词：波形钢腹板梁焊接残余应力热力学数值模拟焊接速度

Use of Evidence-Based Research Approach in RCTs of Acupuncture-Related Therapies for Primary Dysmenorrhea: A Meta-Research

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Chinese Journal of Integrative Medicine 2024年第6期30卷 551-558页

作者： HU Xiao-yi TIAN Zi-yu CHEN Huan HU Xiang-yu MING Tian-yu PENG Hao-xuan jiAO Rui-min SHI Lan-jun XIU Wen-cui YANG ji-wei GANG wei-juan jiNG Xiang-hong Institute of Acupuncture and Moxibustion China Academy of Chinese Medical SciencesBeijingChina Department of Traditional Chinese Medicine Beijing Puren HospitalBeijing100062China

Objective To assess the use of evidence-based research(EBR)approach in randomized controlled trials(RCTs)of acupuncture-related therapies for primary dysmenorrhea(PD).Methods PubMed,EMBASE,Cochrane Library,China National Knowledge Infrastructure,Wanfang Database,Chinese Biomedical Database,and China Science and Technology Journal Database were searched from January 2013 to December 2022 for RCTs of acupuncture on *** full text and references of each RCT were read to assess whether systematic reviews(SRs)or other types of studies with similar research questions and end-users’perspectives were cited to justify and design the *** addition,the discussion section were analyzed to evaluate whether trials placed the new result in the existing SRs to draw a *** logistic regression was used to find variables that associated with 3 aspects of EBR approach:(1)citing clinical studies for justification,(2)citing relevant studies that obtain the perspectives of end users,and(3)citing clinical studies for results *** Of 473 RCTs included,45.67%(216)of the trials cited relevant similar studies,21.56%(102)referenced to the studies that collected end-users’perspectives,and 10.99%(52)placed result in the context of the previous *** RCTs appropriately applied EBR *** all the included studies,3.17%(15)of the trials used SRs to inform study questions but none of them used updated SRs with acceptable quality;1.05%(5)of the trials cited SRs of end-user’s perspectives in the justification and design of the study,and only 1 trial added results in existing SR to draw a *** of publication,language,funding,registration,ethical approval and number of sites were significantly associated with 1 of the 3 aspects of EBR *** Few RCTs in acupuncture-related therapies for PD used the EBR approach to minimize research ***,research institutes,funding agencies,ethics committees,journals and peer

关键词： evidence-based research acupuncture therapy primary dysmenorrhea randomized controlled trial systematic review end-usersperspective meta-research