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Midazolam dose is associated with recurrence of paradoxical reactions during endoscopy

World Journal of Clinical Cases 2021年第29期9卷 8763-8772页

作者： Eun Hyo jin ji hyun song Jooyoung Lee Jung Ho Bae Su jin Chung Department of Internal Medicine Healthcare Research InstituteHealthcare System Gangnam CenterSeoul National University HospitalSeoul 06236South Korea

BACKGROUND Midazolam is commonly used for sedation during gastrointestinal ***,some patients experience paradoxical reactions characterized by excessive movement or *** To investigate the rate of recurrence of paradoxical reactions to midazolam during an upper *** We retrospectively reviewed 122152 sedative endoscopies among a total of 58553 patients at the Seoul National University Hospital,Healthcare System Gangnam Center,from July 2013 to December *** them,361 patients with a history of paradoxical reaction during sedative upper endoscopy were *** characteristics of patients in the recurrent and non-recurrent groups were compared via multivariable analysis using logistic *** Paradoxical reactions occurred in 0.86%(1054/122152)of endoscopies,and in 1.51%(888/58553)of *** the 361 subjects with previous paradoxical reactions in sedative endoscopies,111(30.7%)experienced further paradoxical *** analysis revealed that the total midazolam dose used was higher in the recurrent group(6.74±2.58 mg)than in the non-recurrent group(5.49±2.04 mg;P<0.0001).Patients were administered a lower dose of midazolam than previous doses:1 mg less in the recurrent group and 2 mg less in the non-recurrent *** analysis showed that the midazolam dose difference was an independent risk factor for recurrent paradoxical reaction(odds ratio:1.213,95%CI:1.099-1.338,P=0.0001).CONCLUSION The rate of recurrence of paradoxical reactions is significantly associated with midazolam *** dose of midazolam administered to patients with previous paradoxical reactions should be less than that previously used.

关键词： Gastroscopy Endoscopy Conscious sedation Midazolam Flumazenil

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Effect of structural characteristics on the transport characteristics of solid particles in the thermal storage and release system of circulating fluidized bed

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Particuology 2024年第6期89卷 22-31页

作者： Zengcai ji Guoliang song Zihua Tang Liwei Sun Institute of Engineering Thermophysics Chinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100049China Dalian National Laboratory for Clean Energy Dalian116023China

Coal-fired power generation stands as the most economically viable modulating power source in present-day *** holds the potential to offer prospective solutions to the challenges posed by the rapid expansion of intermittent,unpredictable,and unstable renewable energy *** particle thermal storage technology emerges as an effective means to enhance the flexibility of coal-fired circulating fluidized bed power *** attain an optimized structure for the solid particle thermal storage and release system in circulating fluidized bed units,experimental research was conducted on a 0.1 MWth circulating fluidized bed test *** study delved into the impact of ash storage bin geometries and the shapes of their feed-discharge valves on the control properties of solid particle *** experimental outcomes reveal that employing inverted m-shaped valve and dual U-shaped valves for feed control,alongside U-shaped valves and N-shaped valves for discharge control,both enable efficient and rapid storage and release of solid particles within the circulating fluidized *** similar air distribution conditions,the inverted m-shaped valve exhibits lower conveying energy consumption than the dual U-shaped valves,while the N-shaped valve excels in control characteristics over the U-shaped ***,the inverted m-shaped valve and the N-shaped valve demonstrate optimal overflow port heights,and the ash storage bin exhibits an optimum height-to-diameter ratio.

关键词： Solid particle Thermal storage System structure Transport regulation

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Effect of Air Distribution on the Transport Characteristics of Solid Particles in the Thermal Storage and Release System of Circulating Fluidized Bed

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Journal of Thermal Science 2024年第4期33卷 1554-1563页

作者： ji Zengcai song Guoliang TANG Zihua SUN Liwei State Key Laboratory of Coal Conversion Institute of Engineering ThermophysicsChinese Academy of SciencesBeijing100190China University of Chinese Academy of Sciences Beijing100049China Dalian National Laboratory for Clean Energy Dalian116023China

Solid particle heat storage technology offers a potential solution to the challenges posed by the significant growth of renewable energy sources,particularly in terms of grid security and ***,it has the capability to optimize the energy utilization efficiency of the power *** order to investigate the transport regulation characteristics of solid particles in the thermal storage and release system of a circulating fluidized bed(CFB),a test rig with a capacity of 0.1 MW(th)was *** rig was utilized to systematically study the transport regulation characteristics of solid particles under the double U-type valve feed structure and U-type valve discharge *** experimental findings indicate that the system's design enables efficient and rapid storage and release of solid particles in the *** air distribution mode,specifically the double U-type valve feed structure and the U-type valve discharge structure,significantly influence the feed and discharge characteristics of the ash storage *** was observed that the impact of loose air on these characteristics is more substantial than that of the return air,irrespective of the feed structure or the return *** adjusting the feed and discharge rate,it is recommended to adopt a scheme that involves coarse adjustment through loose air and fine adjustment through return air.

关键词： solid particle thermal storage air distribution mode transport regulation

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World Journal of Gastroenterology 2008年第27期14卷 4359-4364页

作者： Young Hye Byun Jun Haeng Lee Moon Kyung Park ji hyun song Byung-Hoon Min Dong Kyung Chang Young- Ho Kim Hee Jung Son Poong-Lyul Rhee Jae J Kim Jong Chul Rhee ji Hye Hwang Dong Il Park Sang Goon Shim In Kyung Sung Department of Medicine Sungkyunkwan University School of Medicine Samsung Medical Center Department of Physical Medicine and Rehabilitation Sungkyunkwan University School of Medicine Samsung Medical Center Department of Medicine Sungkyunkwan University School of Medicine Kangbuk Samsung Hospital Department of Medicine Sungkyunkwan University School of Medicine Masan Samsung Hospital Department of Internal Medicine Konkuk University College of Medicine

AIM: To determine the prevalence and risk factors of work-related musculoskeletal disorders in gastrointestinal endoscopists in Korea. METHODS: A survey of musculoskeletal symptoms, using a self-administered questionnaire, was conducted on 55 endoscopists practicing in general hospitals or health promotion centers. RESULTS: Forty-nine (89.1%) endoscopists reported musculoskeletal pain on at least one anatomic location and 37 (67.3%) endoscopists complained of pain at rest. Twenty-six (47.3%) endoscopists had severe musculoskeletal pain defined as a visual analogue score greater than 5.5. Factors related to the development of severe pain were (1) standing position during upper endoscopy, (2) specific posture/ habit during endoscopic procedures, and (3) multiple symptomatic areas. Finger pain was more common in beginners, whereas shoulder pain was more common in experienced endoscopists. Sixteen percent of symptomatic endoscopists have modified their practice or reduced the number of endoscopic examinations. Only a few symptomatic endoscopists had sought professional consultation with related specialists. CONCLUSION: The prevalence of musculoskeletal pain in endoscopists is very high. The location of pain was different between beginners and experienced endoscopists. Measures for the prevention and adequate management of endoscopy-related musculoskeletal symptoms are necessary.

关键词： Endoscopy Endoscopist Musculoskeletal symptom

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ChMYB1-ChbHLH42-ChTTG1 module regulates abscisic acidinduced anthocyanin biosynthesis in Cerasus humilis

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Horticultural Plant Journal 2024年第1期10卷 51-65页

作者： Xiaolong ji Zhe Li Mingyu Zhang Shaoyu Lang Xingshun song State Key Laboratory of Tree Genetics and Breeding Northeast Forestry UniversityHarbinHeilongjiang 150040China Department of Genetics College of Life ScienceNortheast Forestry UniversityHarbinHeilongjiang 150040China

Cerasus humilis is a kind of economic fruit tree peculiar to China,which is widely used in the food,landscape,and pharmaceutical *** are a phenolic metabolite that plays an essential role in fruit ***,the regulatory network of *** in anthocyanin biosynthesis is still *** this study,the R2R3-MYB transcription factor ChMYB1 was isolated from the full genome of the *** one-hybrid,dual-luciferase assays,and GUS staining showed that ChMYB1 significantly increased anthocyanin contents in *** fruit by promoting the expression of ChCHS and ChUFGT by binding MBS(MYB-binding elements).ChMYB1 interacted with ChbHLH42and ChTTG1 to form the MBW complex and further enhanced the expression of *** addition,abscisic acid(ABA)treatment promoted the expression of ChMYB1 and anthocyanin accumulation in *** ***,ABA treatment enhanced the interaction between ChMYB1 and ***,ChABI5 inhibited the interaction between ChMYB1 and *** data elucidated the primary molecular mechanism of anthocyanin biosynthesis in *** fruit,deepening the understanding of the regulatory network affecting anthocyanin metabolism in edible fruit crops.

关键词： Cerasus humilis Anthocyanin ChMYB1 Fruit ABA

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Experimental and numerical investigation of the impacts of rotor tip-rake on excitation forces of pump-jet propulsors

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Journal of Hydrodynamics 2024年第1期36卷 142-157页

作者： Xue-qin ji Xiao-song Zhang Chen-jun Yang Xiao-qian Dong State Key Laboratory of Ocean Engineering Marine Numerical Experiment CentreSchool of Naval ArchitectureOcean and Civil EngineeringShanghai Jiao Tong UniversityShanghai200240China CSSC Shanghai Marine Energy Saving Technology Co. Ltd.Shanghai200011China China Ship Scientific Research Center Shanghai Branch Shanghai200011China

The tip-clearance flow in a pump-jet propulsor exerts great impacts on the fluctuating pressures and resultant unsteady forces,which are important sources of structural vibrations and radiated noise *** blade geometry close to the tip is an important factor determining the vortex strength in the tip-clearance *** the open-water condition,the effects of raking the rotor tips on the duct-surface fluctuating pressures and the resultant unsteady forces acting on different components of the propulsor are investigated via physical model experiments and the numerical solution of Reynolds-averaged Navier-Stokes(RANS)equations coupled with the SST k-ωturbulence *** measured and simulated results of hydrodynamic pressures are consistent to each other,and the simulated flows help better understand why the fluctuating pressures change with the tip *** strong fluctuations of duct-surface pressures are caused by intensive tip separation *** duct-surface pressure fluctuations are effectively reduced by using the rake distribution near the tip towards blade back side and,for the combination of the five-bladed rotor and the seven-bladed stator,the resultant unsteady horizontal(and vertical)forces acting on the duct and stator are also reduced;while increasing rake leads to negative effect on pressure fluctuations and unsteady horizontal(and vertical)forces acting on all the components of the propulsor.

关键词： Pump-jet tip-clearance tip-rake fluctuating pressures excitation forces

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Meta Shack–Hartmannwavefront sensor with large sampling density and large angular field of view:phase imaging of complex objects

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Light(Science & Applications) 2024年第9期13卷 1908-1918页

作者： Gi-hyun Go Dong-gu Lee Jaeyeon Oh Gookho song Doeon Lee Mooseok Jang Department of Bio and Brain Engineering Korea Advanced Institute of Science and Technology(KAIST)DaejeonRepublic of Korea

Shack–Hartmann wavefront sensors measure the local slopes of an incoming wavefront based on the displacement of focal spots created by a lenslet array,serving as key components for adaptive optics for astronomical and biomedical ***,the challenges in increasing the density and the curvature of the lenslet have limited the use of such wavefront sensors in characterizing slowly varying wavefront ***,we develop a metasurfaceenhanced Shack–Hartmann wavefront sensor(meta SHWFS)to break this limit,considering the interplay between the lenslet parameters and the performance of *** experimentally validate the meta SHWFS with a sampling density of 5963 permm2 and a maximum acceptance angle of 8°which outperforms the traditional SFWFS by an order of ***,to the best of our knowledge,we demonstrate the first use of a wavefront sensing scheme in single-shot phase imaging of highly complex patterns,including biological tissue *** proposed approach opens up new opportunities in incorporating exceptional light manipulation capabilities of the metasurface platform in complex wavefront characterization.

关键词： angular curvature exceptional

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Anticipating the lifespan: Predicting the durability of an anode-supported solid oxide fuel cell short stack over 50,000 h

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Progress in Natural Science:Materials International 2024年第3期34卷 606-613页

作者： Muhammad Zubair Khan Amjad Hussain Seung-Bok Lee Tak-Hyoung Lim Rak-hyun song Department of Materials Science & Engineering Pak-Austria Fachhochschule: Institute of Applied Sciences and Technology Hydrogen Energy Research Division Korea Institute of Energy Research Department of Advanced Energy and System Engineering Korea University of Science and Technology (UST)

In the present study, the operational lifetime of a solid oxide fuel(SOFC) short stack is predicted by investigating the performance degradation of both the short stack and its cells throughout 1000 h at 800°C. The short stack and integral cell voltages are continuously measured during the long-term test, with electrochemical impedance spectroscopy(EIS) conducted every 200 h. The short stack voltage decreased rapidly for the initial 200–300 h and afterwards, it decreased at a slow rate due to the increase in the Ohmic and polarization resistances in the same manner. Scanning electron microscopy results show that there is no delamination or cracking among constituent layers of the short-stack cells. The single degradation effects of the Ni coarsening in the anode, cation migration and surface segregation in cathode and oxide scale growth in metallic interconnect mesh are successfully integrated into a comprehensive lifetime prediction model. The experimentally measured voltage degradation data of the short stack fits well with the developed mathematical model and allows the successful prediction of the lifetime up to 50,000 h.

关键词： Degradation Impedance Lifetime SOFC Stack

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Crystallization of RE_(2)(OH)_(2)CO_(3)SO_(4)·nH_(2)O as a new family of layered hydroxides(RE=Gd-Lu lanthanides and Y),derivation of RE_(2)O_(2)SO_(4),photoluminescence and optical thermometry

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Journal of Rare Earths 2024年第8期42卷 1496-1506,I0003页

作者： Fan Li Zhenqi song Zhiyuan Pan Sihan Feng Qi Zhu ji-Guang Li Key Laboratory for Anisotropy and Texture of Materials(Ministry of Education) School of Materials Science and EngineeringNortheastern UniversityShenyang110819China Research Center for Functional Materials National Institute for Materials ScienceTSsukuboaIbaraki3050044Japan

Layered rare-earth hydroxides(LREHs) draw wide research interest because of their peculiar crystal structure,rich interlayer chemistry and abundant functionality of the RE element,but are limited to the two categories of RE_(2)(OH)_(5)A·nH_(2)O(A:typical of Cl^(-)or NO_(3)^(-)) and RE_(2)(OH)_(4)SO_(4)·nH_(2)*** the other hand,rare-earth oxysulfates(RE_(2)O_(2)SO_(4)) have attracted attention due to their properties of large-capacity oxygen storage,low-temperature magnetism and luminescence,but their preparation procedure mostly involves toxic SO_(x) gases and/or complicated *** this work,RE_(2)(OH)_(2)CO_(3)SO_(4)·nH_(2)O as a new family of LREHs(RE=Gd-Lu lanthanides and Y) were produced via hydrothermal reaction,from which phase-pure RE_(2)O_(2)SO_(4) was derived via subsequent annealing at 800℃ in air without the involvement of SO_(x),The compounds were thoroughly characterized to reveal the intrinsic influence of lanthanide contraction(RE^(3+) radius) on crystal structure,thermal behavior(dehydroxylation/decarbonation/desulfurization),vibrational property and crystallite *** analyzing the photoluminescence of Eu^(3+) and Sm^(3+)in the Gd_(2)O_(2)SO_(4) typical host it is found that the 617 nm(Eu^(3+),λ_(ex)=275 nm) and 608 nm(Sm^(3+),λ_(ex)=407 nm) main emissions can retain as high as ^(7)9.6% and 85.5%of their room-temperature intensities at 423 K,with activation energies of ~0.19 and 0.21 eV for thermal quenching,*** also indicates that both the phosphors have the potential for optical temperature sensing via the fluorescence intensity ratio(FIR) technology,whose maximum relative sensitivity reaches -2.70%/K for Eu^(3+)and 1.73%/K for Sm^(3+) at 298 K.

关键词： Layered hydroxide RE_(2)O_(2)SO_(4) Luminescence Optical temperature sensing Rare earths

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Unknown system dynamics estimator-based impedance control for lower limb exoskeleton with enhanced performance

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Control Theory and Technology 2024年第1期22卷 56-68页

作者： Wenhao Zhang Peng song Mingying Wu Qiang Li Xinmin Mo Pingxin ji Northwest Institute of Mechanical and Electrical Engineering Xianyang712099ShaanxiChina Xi’an Exo-Smart Dynamics Technology Ltd. Xi’an712046ShaanxiChina Department of Mechanical and Engineering Beijing Institute of TechnologyBeijing100081China

In this article, an unknown system dynamics estimator-based impedance control method is proposed for the lower limb exoskeleton to stimulate the tracking flexibility with the terminal target position when suffering parametric inaccuracies and unexpected disturbances. To reinforce the robust performance, via constructing the filtering operation-based dynamic relation, i.e., invariant manifold, the unknown system dynamics estimators are employed to maintain the accurate perturbation identification in both the hip and knee subsystem. Besides, a funnel control technique is designed to govern the convergence process within a minor overshoot and a higher steady-state precision. Meanwhile, an interactive complaint result can be obtained with the aid of the impedance control, where the prescribed terminal trajectory can be adjusted into the interaction variable-based target position by the force–position mapping, revealing the dynamic influence between the impedance coefficient (stiffness and damping) and the adjusted position magnitude. A sufficient stability analysis verifies the ultimately uniformly bounded results of all the error signals, and even the angle errors can be regulated within the predefined funnel boundary in the whole convergence. Finally, some simulations are provided to demonstrate the validity and superiority including the enhanced interaction flexibility and robustness.

关键词： Trajectory tracking Invariant manifold Funnel control Impedance control Lower limb exoskeleton

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