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Multi-sensing paradigm based urban air quality monitoring and hazardous gas source analyzing:a review

Journal of Safety Science and Resilience 2021年第3期2卷 131-145页

作者： Zhengqiu Zhu Bin Chen yong Zhao Yatai ji College of Systems Engineering National University of Defense Technology(NUDT)410073109 Deya RoadKaifu DistrictChangsha CityHunan provinceChina Research Group of Multi-scale Networked Systems Informatics InstituteUniversity of Amsterdam(UvA)Science Park 904P.O.Box 943231096 XH AmsterdamNetherlands

Effectively monitoring urban air quality,and analyzing the source terms of the main atmospheric pollutants is important for public authorities to take air quality management *** works,such as long-term obser-vations by monitoring stations,cannot provide customized data services and in-time emergency response under urgent situations(gas leakage incidents).Therefore,we first review the up-to-date approaches(often machine learning and optimization methods)with respect to urban air quality monitoring and hazardous gas source *** bridge the gap between present solutions and practical requirements,we design a conceptual framework,namely MAsmed(Multi-Agents for sensing,monitoring,estimating and determining),to provide fine-grained concentration maps,customized data services,and on-demand emergency *** this framework,we leverage the hybrid design of wireless sensor networks(WSNs)and mobile crowdsensing(MCS)to sense urban air quality and relevant data(*** data,meteorological data,etc.);Using the sensed data,we can create a fine-grained air quality map for the authorities and relevant stakeholders,and provide on-demand source term estimation and source searching methods to estimate,seek,and determine the sources,thereby aiding decision-makers in emergency response(*** evacuation).In this paper,we also identify several potential opportunities for future research.

关键词： Urban air quality monitoring and source analyzing system MAsmed framework Wireless sensor networks Mobile crowdsensing Air quality management

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Exploring the obscure profiles of pharmacological binding sites on voltage-gated sodium channels by BmK neurotoxins

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Protein & Cell 2011年第6期2卷 437-444页

作者： Zhi-Rui Liu Pin Ye yong-Hua ji Laboratory of Neuropharmacology and Neurotoxicology Shanghai UniversityShanghai 200444China

Diverse subtypes of voltage-gated sodium channels(VGSCs)have been found throughout tissues of the brain,muscles and the *** extracted from the venom of the Asian scorpion Buthus martensi Karsch(BmK)act as sodium channel-specific modulators and have therefore been widely used to study VGSCs.α-type neurotoxins,named BmK I,BmKαIV and BmK abT,bind to receptor site-3 on VGSCs and can strongly prolong the inactivation phase of *** contrast,β-type neurotoxins,named BmK AS,BmK AS-1,BmK IT and BmK IT2,occupy receptor site-4 on VGSCs and can suppress peak currents and hyperpolarize the activation kinetics of sodium *** evidence from binding assays of scorpion neurotoxins on VGSCs,however,indicate that pharmacological sensitivity of VGSC subtypes to different modulators is much more complex than that suggested by the simpleα-type and β-type neurotoxin *** the mechanisms of possible dynamic interactions between site 3-/4-specific modulators and region-and/or speciesspecific subtypes of VGSCs would therefore greatly expand our understanding of the physiological and pharmacological properties of diverse *** this review,we discuss the pharmacological and structural diversity of VGSCs as revealed by studies exploring the binding properties and cross-competitive binding of site 3-or site 4-specific modulators in VGSC subtypes in synaptosomes from distinct tissues of diverse species.

关键词： voltage-gated sodium channel receptor sites scorpion neurotoxins

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Osmotic Regulation of Betaine Content in Leymus chinensis Under Saline-alkali Stress and Cloning and Expression of Betaine Aldehyde Dehydrogenase(BADH) Gene

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Chemical Research in Chinese Universities 2008年第2期24卷 204-209页

作者： CUI Xi-yan WANG yong GUO ji-xun Key Laboratory for Vegetation Ecology of Ministry of Education Institute of Grassland Science Northeast Normal University Changchun 130024 P. R. China School of Life Sciences Jilin Agricultural University Changchun 130118 P. R. China

The potted Leymus chinensis seedlings were treated with saline-alkali solution of six different（from Ⅰ to Ⅵ） concentrations. The results demonstrate that the betaine content and Betaine-aldehyde dehydrogenase（BADH： EC 1.***.1.8） activities have a direct relation with increased stressing time in the same treatment; both exhibit a single peak with increasing the concentration of saline-alkali solution, and number V shows the highest value. The BADH gene of Leyrnus chinensis was cloned by RT-PCR and RACE technology and was designated as LcBADH. The cDNA sequence of LcBADH was 1774bp including the open reading frame（ORF） of 1521bp（coding 506 amino acids）. The vector of prokaryotic expression was constructed by inserting the LcBADH gene fragmcnt into pET30a（＋） and transformed into E. coli BL21（DE3）. The result of SDS-PAGE shows that the idio-protein with a molecular mass of 56.78 kDa was effectively expressed in the recombinant bacteria induced by isopropyl fl-D-thiogalactoside（IPTG）.

关键词： Leymus chinensis Saline-alkali stress BADH RACE Cloning and expression

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Design for Isothermal Forging of Ti-46.5Al-2.5V-1.0Cr-0.3Ni Alloy

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Journal of Iron and Steel Research International 2010年第8期17卷 67-73页

作者： SI jia-yong haN Peng-biao ZhaNG ji Institute of Processing Technologies of Materials Central South University of Forestry and TechnologyChangsha 410004HunanChina High Temperature Material Research Division Central Iron andSteel Research InstituteBeijing 100081China

The three-dimensional finite element method was utilized to investigate the isothermal forging of Ti-46.5Al-2.5V-1.0Cr-0.3Ni（atomic percent,%）*** partition of height reduction,effective strain,and damage of the alloy during the forging were *** simulation results were verified by *** results show that large plastic deformation can improve the homogeneity of the deformed microstructure and the higher accumulative height reduction can be achieved through two-step *** the isothermal forging of two-step reduction of 60%＋62.5%（total height reduction of 85%）,the entire forged pancake can acquire refined microstructure and expand the uniform flow zone to almost the entire volume.

关键词： titanium aluminide isothermal forging multistep forging FEM simulation

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Investigation into Hydrogen Diffusion and Susceptibility of Hydrogen Embrittlement of High Strength 0Cr16Ni5Mo Steel

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Journal of Iron and Steel Research International 2015年第10期22卷 961-968页

作者： yong-wei SUN ji-zhi CHEN Jun LIU College of Materials Science and Chemical Engineering Harbin Engineering University Luoyang Ship Material Research Institute

High strength bolt steel 0Crl6Ni5Mo was charged with hydrogen by means of electrochemical technique to evaluate the hydrogen diffusion behavior. The bolt steels were investigated by a combination of electrochemical hydrogen permeation, thermal desorption spectroscopy （TDS）, slow strain rate test （SSRT） and microstructure observation. The hydrogen concentration of both 10.9 grade （Rm=950-1 150 MPa） and 12.9 grade （Rm=1 150-1 250 MPa） bolt steels increases with increasing the hydrogen charging current densities and charging time. The 12.9 grade bolt steel has higher apparent diffusion coefficient than 10.9 grade steel, corresponding to the value of 4.7×10 7 mm^2/s. By means of TDS tests, the activation energies of the two experimental steels are 17.74 kJ/mol and 18.92 kJ/mol, respectively. The hydrogen traps of both grade bolt steels are dislocations and crystal lattice. The notch tensile strength of the steels is reduced with the hydrogen concentration carried out by SSRT. The fracture morphologies of the steels after hydrogen charging present ductile dimple and quasi-cleavage characteristic.

关键词： 0Cr16Ni5Mo steel hydrogen diffusion hydrogen permeation thermal desorption spectroscopy slow strain rate test

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Variable selection via generalized SELO-penalized linear regression models

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Applied Mathematics(A Journal of Chinese Universities) 2018年第2期33卷 145-162页

作者： SHI Yue-yong CAO yong-xiu YU ji-chang jiAO Yu-ling School of Econoraics and Management China University of GeosciencesWuhan 430074China School of Statistics and Mathematics Zhongnan University of Economics and LawWuhan 430073China Center for Resources and Environmental Economic Research China University of GeosciencesWuhan 430074China

The seamless-L0 （SELO） penalty is a smooth function on [0, ∞） that very closely resembles the L0 penalty, which has been demonstrated theoretically and practically to be effective in nonconvex penalization for variable selection. In this paper, we first generalize SELO to a class of penalties retaining good features of SELO, and then propose variable selection and estimation in linear models using the proposed generalized SELO （GSELO） penalized least squares （PLS） approach. We show that the GSELO-PLS procedure possesses the oracle property and consistently selects the true model under some regularity conditions in the presence of a diverging number of variables. The entire path of GSELO-PLS estimates can be efficiently computed through a smoothing quasi-Newton （SQN） method. A modified BIC coupled with a continuation strategy is developed to select the optimal tuning parameter. Simulation studies and analysis of a clinical data are carried out to evaluate the finite sample performance of the proposed method. In addition, numerical experiments involving simulation studies and analysis of a microarray data are also conducted for GSELO-PLS in the high-dimensional settings.

关键词： continuation coordinate descent BIC LLA oracle property SELO smoothing quasi-Newton

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Mechanical and electrical properties of In-Bi solder at Bi_(2212) superconductor interface with annealed Ag spray layers and Ag precoating layers

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中国有色金属学会会刊：英文版 2009年第4期19卷 961-964页

作者： Seung-yong SHIN ji-Hyun LEE hai-Woong PARK Department of Materials Engineering Korea University of Technology and Education(KUT)

The electrical properties of solder contact layers between Cu-Ni shunt metal and tube type Bi2212 superconductor that is applied in superconducting fault current limiter were *** contact properties of the solders are improved not only by Ag precoating layers,but also by the pre-sprayed Ag layer and subsequent Ag precoating *** annealed Ag sprayed layers onto Bi2212 superconductor prior to Ag electroplating work as protecting layers for the superconductor from plating *** contact angle of the electroplated Ag layer is 42.91° and decreases to 15.25° and 5.88° with Ag sprayed layer and additional Ag electroplated *** Ag sprayed layer with suitable annealing prior to Ag electroplating improves contact strength of the Ag electroplated layer by about 12% due to denser microstructure of the Ag electroplated layers.

关键词：超导故障限流器 Bi2212 电镀银电气性能喷涂层预涂层退火焊料

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Electroless deposition of Ni on template of halloysite and its magnetic property

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中国有色金属学会会刊：英文版 2004年第Z1期14卷 152-156页

作者： FU Yu-bin ZhaNG Li-de ZHENG ji-yong Institute of Solid State Physics Chinese Academy of Sciences Hefei 230031 China Luoyang Ship Material Research Institute Luoyang 471039 China Institute of Solid State Physics Chinese Academy of Sciences Hefei 230031 China Luoyang Ship Material Research Institute Luoyang 471039 China

halloysite template, a ceramic substrate, is of a hollow cylindric structure, on which the fine Pd nanoparticles are uniformly formed by the reduction of palldate chloride to initiate electroless deposition. The electroless deposition of Ni is catalyzed by the Pd particles, which results in a uniform layer of Ni-P alloy on halloysite. The alloy is of a nanocrystalline structure, of which the average diameter is about 6 nm. After being heat-treated at 400 ℃, it contains both Ni and Ni12P5 crystal, meanwhile, the Ni crystal gets larger with an average size of 51.9 *** content of phosphorous in the Ni layer has a great influence on crystal structure. The metallized halloysite has a higher inherent coercive force, and a much lower saturation magnetization in its as-plated state, while after heattreatment, the inherent coercive force decreases drastically. These magnetic properties have great relationship with the superparamagnetism of Ni nanocrystalline and the stress anisotropy in Ni layer.

关键词： halloysite template electroless deposition Ni nanocrystalline inherent coercive force

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Emerging role of Toll-like receptors in the control of pain and itch

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Neuroscience Bulletin 2012年第2期28卷 131-144页

作者： Tong Liu yong-jing Gao Ru-Rong ji Sensory Plasticity Laboratory Pain Research CenterDepartment of AnesthesiologyPerioperative and Pain MedicineBrigham and Women's Hospital and Harvard Medical SchoolBostonMassachusetts 02115USA Institute of Nautical Medicine Nantong UniversityNantong 226001China

Toll-like receptors （TLRs） are germline-encoded pattern-recognition receptors that initiate innate immune re- sponses by recognizing molecular structures shared by a wide range of pathogens, known as pathogen-associated molecular patterns （PAMPs）. After tissue injury or cellular stress, TLRs also detect endogenous ligands known as danger-associated molecular patterns （DAMPs）. TLRs are expressed in both non-neuronal and neuronal cell types in the central nervous system （CNS） and contribute to both infectious and non-infectious disorders in the CNS. Following tissue insult and nerve injury, TLRs （such as TLR2, TLR3, and TLR4） induce the activation of microglia and astrocytes and the production of the proinflammatory cytokines in the spinal cord, leading to the development and maintenance of inflammatory pain and neu- ropathic pain. In particular, primary sensory neurons, such as nociceptors, express TLRs （e.g., TLR4 and TLR7） to sense exogenous PAMPs and endogenous DAMPs released after tissue injury and cellular stress. These neuronal TLRs are new players in the processing of pain and itch by increasing the excitability of primary sensory neurons. Given the prevalence of chronic pain and itch and the suffering of affected people, insights into TLR signaling in the nervous system will open a new avenue for the management of clinical pain and itch.

关键词： astrocytes microglia Toll-like receptor pain itch danger-associated molecular patterns pathogen-associatedmolecular patterns

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Ethanolic extract of dandelion(Taraxacum mongolicum) induces estrogenic activity in MCF-7 cells and immature rats

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Chinese Journal of Natural Medicines 2015年第11期13卷 808-814页

作者： Seung Min Oh ha Ryong Kim yong Joo Park yong Hwa Lee Kyu Hyuck Chung Fusion Technology Laboratory Hoseo University School of Pharmacy Sungkyunkwan University

Plants of the genus Taraxacum, commonly known as dandelions, are used to treat breast cancer in traditional folk medicine. However, their use has mainly been based on empirical findings without sufficient scientific evidence. Therefore, we hypothesized that dandelions would behave as a Selective estrogen receptor modulator （SERM） and be effective as hormone replacement therapy （HRT） in the postmenopausal women. In the present study, in vitro assay systems, including cell proliferation assay, reporter gene assay, and RT-PCR to evaluate the mRNA expression of estrogen-related genes （pS2 and progesterone receptor, PR）, were performed in human breast cancer cells. Dandelion ethanol extract （DEE） significantly increased cell proliferation and estrogen response element （ERE）-driven luciferase activity. DEE significantly induced the expression of estrogen related genes such as pS2 and PR, which was inhibited by tamoxifen at 1 gmol L-1. These results indicated that DEE could induce estrogenic activities mediated by a classical estrogen receptor pathway. In addition, immature rat uterotrophic assay was carried out to identify estrogenic activity of DEE in vivo. The lowest concentration of DEE slightly increased the uterine wet weight, but there was no significant effect with the highest concentration of DEE. The results demonstrate the potential estrogenic activities of DEE, providing scientific evidence supporting their use in traditional medicine.

关键词： Dandelion extract Estrogenic activity MCF-7 cells Immature rat uterotrophic assay

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