检索结果-南通市图书馆

Decreased levels of phosphorylated synuclein in plasma are correlated with poststroke cognitive impairment

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2025年第9期20卷 2598-2610页

作者： Yi Wang Yuning Li Yakun Gu wei Ma Yuying Guan Mengyuan Guo Qianqian Shao Xunming ji jia Liu Department of Clinical Laboratory Beijing Bo’ai HospitalChina Rehabilitation Research CenterCapital Medical UniversityBeijingChina Beijing Institute of Brain Disorders Laboratory of Brain DisordersMinistry of Science and TechnologyCollaborative Innovation Center for Brain DisordersBeijing Advanced Innovation Center for Big Data-based Precision MedicineCapital Medical UniversityBeijingChina Department of Neurosurgery Xuanwu HospitalCapital Medical UniversityBeijingChina

Poststro ke cognitive impairment is a major secondary effect of ischemic stroke in many patients;however,few options are available for the early diagnosis and treatment of this *** aims of this study were to(1)determine the specific relationship between hypoxic andα-synuclein during the occur of poststroke cognitive impairment and(2)assess whether the serum phosphorylatedα-synuclein level can be used as a biomarker for poststro ke cognitive *** found that the phosphorylatedα-synuclein level was significantly increased and showed pathological aggregation around the cerebral infa rct area in a mouse model of ischemic *** addition,neuronalα-synuclein phosphorylation and aggregation were observed in the brain tissue of mice subjected to chronic hypoxia,suggesting that hypoxia is the underlying cause ofα-synuclein-mediated pathology in the brains of mice with ischemic *** phosphorylatedα-synuclein levels in patients with ischemic stroke were significantly lower than those in healt hy subjects,and were positively correlated with cognition levels in patients with ischemic ***,a decrease in serum high-density lipoprotein levels in stroke patie nts was significantly correlated with a decrease in phosphorylatedα-synuclein *** ischemic stroke mice did not show significant cognitive impairment or disrupted lipid metabolism 14 days after injury,some of them exhibited decreased cognitive function and reduced phosphorylatedα-synuclein *** together,our results suggest that serum phosphorylatedα-synuclein is a potential biomarker for poststroke cognitive impairment.

关键词： biomarker high-density lipoprotein ischemic stroke phosphorylatedα-synuclein poststroke cognitive impairment

Efficacy comparison of different therapy selection on hepatocellular carcinoma complicated with cancer thrombi in bile duct

在线全文

学校读者我要写书评

暂无评论

Efficacy comparison of different therapy selection on hepato...

中国抗癌协会胆道肿瘤专业委员会成立大会暨第一届全国胆道肿瘤学术会议

作者： Luo Xiang-ji,tan wei-feng,Yi Bin,Liu Chen,jiang Xiao-qing,Zhang Bai-he,Shen Feng,Wu Meng-chao Department of Biliary SurgeryⅠ,Eastern Hepatobiliary Surgery Hospital,Second Military Medical University

Purpose This study retrospectively compared different resection methods and other interventions in patients with hepatocellular carcinoma(HCC) complicated by bile duct thrombi(BDT). Methods A total of 184 patients with BDT were selected from a pool of 12,114 patients with HCC and their cases were reviewed in this *** The mean survival time in patients who underwent hepatic resection and BDT removal(group A),palliative hepatectomy and BDT removal(group B),palliative hepatectomy and BDT removal plus unilateral liver artery ligation or postoperative transcatheter arterial chemoembolization (TACE)(group C),TACE(group D),drainage to relieve the jaundice by ERCP or PTCD(group E), and conservative treatment(group F) was 37,6,16,11,3.0,3.0 months *** survival rate of patients in group group A was significantly greater than in other groups(P<0.0001);the rate in groups C and D was significantly higher than that in groups B,E,and F(P<0.001).Conclusions Hepatic resection and removal of BDT,combined with TACE,is the best approach for treating HCC patients with BDT.

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

脊柱骨转移瘤的MR去脂序列表现

实用放射学杂志 2006年第1期22卷 73-75页

作者：张祥林何翠菊马贺骥谭威赵为锦州医学院附属一院放射科锦州医学院附属一院放射科辽宁锦州121001

目的探讨脊柱骨转移瘤的MR去脂序列的影像学特征。方法对70例脊柱转移瘤患者MR图像进行回顾性分析。结果脊柱骨转移瘤的信号改变明显,所有病灶椎体信号均有改变,其中去脂T2W I序列中病灶表现为中等高信号为100%,均高于周围正常椎体信号... 详细信息

目的探讨脊柱骨转移瘤的MR去脂序列的影像学特征。方法对70例脊柱转移瘤患者MR图像进行回顾性分析。结果脊柱骨转移瘤的信号改变明显,所有病灶椎体信号均有改变,其中去脂T2W I序列中病灶表现为中等高信号为100%,均高于周围正常椎体信号;脊柱骨转移瘤累及附件、椎旁软组织肿块的形成和邻近椎间盘的无受累对与其他疾病的鉴别诊断具有重要意义。结论MR去脂序列应作为怀疑脊柱骨转移瘤的常规检查手段。

关键词：脊柱转移瘤磁共振成像

Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Traditional Medicine Research 2025年第1期10卷 73-81页

作者： Xiao-Long Zhou wei-jin jiang ji Yu Mao-Jun Yao Yun-Tong Li Hunan Provincial Key Laboratory of Research Resource Mining and High-valued Utilization on Edible&Medicinal PlantCollege of Chemistry and Chemical EngineeringJishou UniversityJishou 416000China Hunan Gaoge Dairy Co. Ltd.Changsha 410000China

Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in *** vine tea processing,a large amount of broken tea is produced,which has low commercial ***:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea ***:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid *** chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted ***,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE *** vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant ***:The findings suggest that extraction methods signi

关键词： vine tea dihydromyricetin ultrasonic-assisted extraction volatile aroma components

Synthesis of structurally diversified BINOLs and NOBINs via palladium-catalyzed C-H arylation with diazoquinones

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Chemistry 2021年第9期64卷 1515-1521页

作者： ji-wei Zhang Fei jiang Ye-Hui Chen Shao-Hua Xiang Bin tan School of Chemistry and Chemical Engineering Harbin Institute of TechnologyHarbin150001China Shenzhen Grubbs Institute and Department of Chemistry Southern University of Science and TechnologyShenzhen518055China Academy for Advanced Interdisciplinary Studies Southern University of Science and TechnologyShenzhen518055China

Privileged biaryl frameworks,BINOL and NOBIN,were efficiently constructed with sole 1-DNQs as arylation reagents under one set of reaction *** judicious selection of palladium-catalytic system plays a pivotal role in the excellent *** transformation accommodated fairly broad substrate generality for both 2-naphthol and N-Boc-2-naphthylamine and afforded the structurally diversified BINOLs and NOBIN derivatives in high ***,the bromosubstituents which cannot survive in conventional palladium-catalyzed reactions were well-compatible with this set of conditions,providing an effective handle for further enriching the library of BINOLs and *** attempts on the asymmetric variant of this reaction were also performed with up to 80:20 er for BINOLs synthesis.

关键词： BINOLs NOBINs high selectivity C-H arylation palladium-catalysis

汽柴油加氢精制装置职业危害控制效果评价及评价体系存在的问题

在线全文

学校读者我要写书评

暂无评论

新疆医科大学学报 2006年第1期29卷 18-20页

作者：王英霁刘继文谭卫国杨晓燕新疆医科大学公共卫生学院劳动卫生与环境卫生学教研室新疆乌鲁木齐830054

目的:评价汽柴油加氢精制装置职业性危害及建设项目职业病危害控制效果评价实施中存在的问题。方法:根据建设项目职业病危害评价规范中规定的方法对克拉玛依市石化公司45×104t／a汽柴油加氢精制装置进行控制效果评价。结果:我国现阶段... 详细信息

目的:评价汽柴油加氢精制装置职业性危害及建设项目职业病危害控制效果评价实施中存在的问题。方法:根据建设项目职业病危害评价规范中规定的方法对克拉玛依市石化公司45×104t／a汽柴油加氢精制装置进行控制效果评价。结果:我国现阶段在进行建设项目职业病危害控制效果评价时现场采样标准和卫生评价标准脱节;评价中遇到了规范不太明确的问题,尤其是噪声等物理因素的评价计算问题;多数建设项目不向职业卫生服务机构申请建设项目职业病危害评价;有的建设项目在厂区和作业岗位未设置职业病危害的公告栏和警示说明,有关职业病防治的规章制度也不完善。结论:此控制效果评价项目职业卫生达到标准要求,基本符合国家有关职业卫生标准规范。职业病危害控制效果评价技术水平有待提高。职业病危害控制效果评价忽视了不良工作因素对健康的影响、工作相关疾病的评价及对管理、保健措施的评价。

关键词：石油化工建设项目职业危害评价

Distinct effect of preparation methods on reaction efficiency of Mn-Ce/Al_(2)O_(3) catalysts in low-temperature NH_(3)-SCR

在线全文

学校读者我要写书评

暂无评论

Journal of Rare Earths 2024年第10期42卷 1865-1872页

作者： Shijie Hao Yandi Cai wei wei Yanan Lv jiawei ji wei tan jingfang Sun Liwei jia Changjin tang Lin Dong State Key Laboratory of Pollution Control and Resource Reuse School of EnvironmentJiangsu Key Laboratory of Vehicle Emissions ControlCenter of Modern AnalysisKey Laboratory of Mesoscopic Chemistry of MOESchool of Chemistry and Chemical EngineeringNanjing UniversityNanjing210023China Wuxi weifu Environmental Catalysts Co. LtdWuxi214028China School of Environment Nanjing Normal UniversityNanjing210023China

In this study,a series of Mn-Ce/Al_(2)O_(3) catalysts was prepared by different methods of depositionprecipitation(MnCeAl-DP),impregnation(MnCeAl-IM) and citric acid(MnCeAl-CA),and the distinct effect of preparation methods on NO_(x) removal performance at low temperature was *** show that MnCeAl-DP exhibits not only the best activity but also the highest resistance against SO_(2)/H_(2)*** the assistance of comprehensive characterizations from scanning electron microscopy(SEM),Brunauer-Emmett-Teller(BET),X-ray diffraction(XRD),H_(2)-temperature programmed reduction(H_(2)-TPR),NH_(3)-te mperature programmed deso rption(NH_(3)-TPD),and X-ray photoelectron spectroscopy(XPS),it is revealed that the MnCeAl-DP sample owns admired features of large surface area and pore volume,enriched Mn^(4+) and chemisorbed oxygen species originating from enhanced interaction between MnO_x and CeO_(2),as well as improved adsorption capacity to NH_(3) and *** these factors contribute to activity *** in-situ DRIFTS studies reveal that the improvement of NH_(3)-SCR performance over MnCeAI-DP is related to the formation of abundant nitrate species,which is beneficial to the "NH_(4)NO_(3)" reaction pathway and thus enhances low-temperature activity.

关键词： Mn-Ce/Al_(2)O_(3)catalysts NH_(3)-SCR Low temperature NH_(4)NO_(3) Fast SCR Rare earths

Direct Construction of NOBINs via Domino Arylation and Sigmatropic Rearrangement Reactions

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Chemistry 2020年第12期38卷 1503-1514页

作者： ji-wei Zhang Liang-Wen Qi Shaoyu Li Shao-Hua Xiang Bin tan School of Chemistry and Chemical Engineering Harbin Institute of TechnologyHarbinHeilongjiang 150001China Shenzhen Grubbs Institute and Department of Chemistry Southern University of Science and TechnologyShenzhenGuangdong 518055China Academy for Advanced Interdisciplinary Studies Southern University of Science and TechnologyShenzhenGuangdong 518055China

of main observation and conclusion Privileged 2-amino-2,-hydroxy-l/l,-binaphthyl(NOBIN)frameworks were constructed through a novel domino arylation of naphthylhydroxylamines with diarylhalonium salts and sigmatropic rearrangement in a transition metal-free *** protocol bears broad substrate generality and proceeds under mild reaction conditions,affording diversified NOBINs in high efficiency with absolute regiocontrol during the rearrangement *** active product was accessible by chiral A/-heterocyclic carbene-catalyzed kinetic resolution in one pot or diastereoselective[3,3]-rearrangement guided by a removable chiral ***,diarylchloronium and diarylbrominium salts have been employed as arylation reagents for the first time in assembling such representative biaryl frameworks.

关键词： process. rearrangement salts

The effects of ultrasound frequency and power on the activation energy in Si-KOH reaction system

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2014年第4期25卷 617-620页

作者： Qing-Bin jiao Bayanheshig Xin tan ji-wei Zhu jian-Xiang Gao Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of Sciences University of Chinese Academy of Sciences ChAngchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of Sciences

The activation energy is the minimum amount of energy required to initiate a reaction. It is one of the important indexes for appraising a reaction. The chemical reaction rate is closely related to the value of activation energy, and reducing activation energy is propitious to promoting a chemical reaction. In the present paper, the relationship between the activation energy in Si-KOH reaction system and the ultrasound frequency and power has been discussed for the first time. The range of ultrasound frequency and power is 40-100kHz （interval by 20kHz） and 10-50W （interval by 10W）, respectively. The experimental clata indicate that the activation energy decreases with the increasing ultrasound power. Comparing with the activation energy without ultrasound irradiation, the results in our paper indicate that ultrasound irradiation could reduce the activation energy in Si-KOH reaction system and increase the reaction rate.

关键词： Si-KOH Etching rate Ultrasonic irradiation Activation energy