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Journal of Materials Science & Technology 2023年第9期140卷 187-200页

作者： SeungHyeok Chung ji Ho shin Ho jin Ryu Department of Nuclear and Quantum Engineering Korea Advanced Institute of Science and Technology(KAIST)Daejeon 34141Republic of Korea Central Research Institute Korea Hydro and Nuclear Power Co.Ltd.(KHNP)Daejeon 34101Republic of Korea

Dispersoid formation and microstructural evolution in an oxide dispersion-strengthened CoCrFeMnNi high-entropy alloy(HEA)using a newly designed multistep sintering process are *** proposed multistep sintering consists of a dispersoid preforming heat treatment of as-milled 0.1 wt%Y_(2)O_(3)-CoCrFeMnNi high-entropy alloy powders at 800℃,followed by sintering at 800–1000℃ under uniaxial *** the conventional single-step sintered bulk,the coarsened BCC Y_(2)O_(3)dispersoids mainly form with an incoherent interface with the HEA *** contrast,finer FCC Y_(2)O_(3)dispersoids,an atypical form of Y_(2)O_(3),are formed in the matrix region after multistep *** of FCC Y_(2)O_(3)disper-soids is initiated on the favorable facet,the{111}plane of the austenitic matrix,with the formation of a semi-coherent interface with the matrix during the dispersoid preforming heat treatment and it maintains its refined size even after *** is found that dispersoid preforming prior to sintering appears promising to control the finer dispersoid formation and refined grain structure.

关键词： Oxide dispersion strengthening High-Entropy alloy Multistep sintering Dispersoid preforming Microstructure evolution Interfacial structure

Korean Morphological Analysis for Korean-Vietnamese Statistical Machine Translation

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Journal of Electronic Science and Technology 2017年第4期15卷 413-419页

作者： Quang-Phuoc Nguyen Joon-Choul shin cheol-Young Ock Department of IT Convergence University of Ulsan Ulsan 44610 Republic of Korea

This paper describes the experiments with Korean-to-Vietnamese statistical machine translation(SMT). The fact that Korean is a morphologically complex language that does not have clear optimal word boundaries causes a major problem of translating into or from Korean. To solve this problem, we present a method to conduct a Korean morphological analysis by using a pre-analyzed partial word-phrase dictionary(PWD).Besides, we build a Korean-Vietnamese parallel corpus for training SMT models by collecting text from multilingual magazines. Then, we apply such a morphology analysis to Korean sentences that are included in the collected parallel corpus as a preprocessing step. The experiment results demonstrate a remarkable improvement of Korean-to-Vietnamese translation quality in term of bi-lingual evaluation understudy(BLEU).

关键词： Factored translation models Korean-Vietnamese parallel corpus morphological analysis statistical machine translation(SMT)

Effect of pre-deformation on precipitation behavior of AZ80 alloy:Comparison of slip-and twinning-dominant deformation

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Journal of Magnesium and Alloys 2024年第9期12卷 3616-3630页

作者： Hyun ji Kim Sang cheol jin Sumi Jo Sung Hyuk Park Department of Materials Science and Metallurgical Engineering Kyungpook National UniversityDaegu 41566Republic of Korea Graduate School of Materials Science and Engineering Kyungpook National UniversityDaegu 41566Republic of Korea

This study investigates the effect of the deformation mode on the precipitation behavior of an extruded Mg-8.0Al-0.5Zn-0.2Mn(AZ80)*** alloy samples are compared after the application of 3.5%tension and 3.5%compression along the extrusion direction to induce slip-dominant and twinning-dominant deformation modes,*** pre-compressed(PC)sample,which contained numerous{10-12}tension twins,has a reduced grain size and a higher internal strain than the pre-tensioned(PT)sample,which is attributed to the inherent internal strain that occurs during the formation and growth of the *** a result,the precipitation behavior of the PC sample is accelerated,leading to its short peak aging time of 32 h,which is lower than those of the PT and as-extruded samples(48 and 100 h,respectively).Furthermore,fine continuous precipitates(CPs)rapidly form within the{10-12}twins,contributing to the enhanced *** precipitates(DPs),which have a hardness comparable to the CP-containing twinned regions,in the PC sample experience less coarsening during aging than those in the PT sample due to growth inhibition by the{10-12}***,the{10-12}twins generated under the twinning-dominant deformation condition lead to enhanced precipitation behaviors,including the preferential formation and refinement of CPs and the suppressed coarsening of ***,pre-deformation that occurs{10-12}twinning exhibits more pronounced effects on precipitation acceleration and microstructural modification than slip-inducing pre-deformation.

关键词： AZ80 alloy Slip Twinning Precipitation Hardness

Observational Study Evaluation of clinical application of Korean medicine standard clinical pathway in a public hospital

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World Journal of Clinical Cases 2025年第17期13卷 16-26页

作者： Seung-Jae shin jin-Won Kim ji-Cheon Jeong Department of Korean Medicine The Graduate SchoolDongguk UniversityGyeonggi-do 10326South Korea Department of Internal Medicine of Korean Medicine National Medical CenterSeoul 04564South Korea Department of Internal Medicine College of Korean MedicineDongguk UniversityGyeonggi-do 10326South Korea

BACKGROUND Clinical pathways(CPs)are structured guidelines introduced to improve healthcare quality and *** South Korea,CPs for Korean medicine have been developed since 2016 under the 3rd Comprehensive Plan for Korean Medicine Promotion,with limited studies on their clinical *** and shoulder pain are common conditions frequently treated at Korean medicine clinics,often by patients dissatisfied with conventional *** demand for Korean medicine treatments for neck and shoulder pain is on the *** To evaluate the clinical applicability and effectiveness of Korean medicine CPs for neck pain and shoulder pain in public healthcare institutions in South *** We collected and analyzed data from patients aged 19 years and older who visited the outpatient clinic of the Department of Korean Medicine at the National Medical Center in Korea from March 1,2023 to August 31,*** completion rates,along with patient satisfaction,clinical outcomes,and economic outcomes between the CP-implemented and non-CP groups were *** The CP completion rates were 93.3%for neck pain and 96.8%for shoulder *** satisfaction scores showed an improvement of 17.7%for neck pain and 18.0%for shoulder pain in the CP-implemented group compared to the non-CP *** neck pain,significant improvements were observed in the numerical rating scale(NRS)and the neck disability index,while for shoulder pain,only the University of California-Los Angeles shoulder rating scale showed notable progress,with no substantial change in NRS *** This study partially confirms the clinical applicability and effectiveness of the Korean medicine CPs for neck pain and shoulder *** research is required to enhance and validate these findings.

关键词： Clinical pathways Korean medicine Public healthcare Neck pain Shoulder pain

Moxifloxacin-containing triple therapy after non-bismuth quadruple therapy failure for Helicobacter pylori infection

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World Journal of Gastroenterology 2015年第46期21卷 13124-13131页

作者： ji Hyun Lim Dong Ho Lee Seong Tae Lee Nayoung Kim Young Soo Park cheol Min shin In Sung Song Department of Internal Medicine Seoul National University Bundang Hospital

AIM: To assess the efficacy of moxifloxacin-containing triple therapy after non-bismuth quadruple therapy failure for Helicobacter pylori(H. pylori) ***: Between January 2010 and December 2012,we screened individuals who were prescribed non-bismuth quadruple therapy for H. pylori eradication. Among them,a total of 98 patients who failed non-bismuth quadruple therapy received 1-wk or 2-wk moxifloxacin-containing triple therapy(400 mg moxifloxacin once daily,and 20 mg of rabeprazole and 1 g of amoxicillin twice daily). H. pylori status was evaluated using the 13C-urea breath test 4 wk later,after treatment completion. The eradication rates were determined by intention-to-treat and per-protocol ***: In total,60 and 38 patients received 1-wk and 2-wk moxifloxacin-containing triple therapy,respectively. The intention-to-treat and per-protocol eradication rates were 56.7%(95%CI: 45.0-70.0) and 59.6%(95%CI: 46.6-71.7) in the 1-wk group and 76.3%(95%CI: 63.2-89.5) and 80.6%(95%CI: 66.7-91.9) in the 2-wk group(P = 0.048 and 0.036,respectively). All groups had good compliance(95% vs 94.9%). Neither group showed serious adverse events,and the proportions of patients experiencing mild side effects were not significantly different(21.1% vs 13.9%). Clinical factors such as age,sex,alcohol and smoking habits,comorbidities,and presence of gastric or duodenal ulcer did not influence the eradication therapy efficacy. The efficacy of second-line eradication therapy did not differ significantly according to the firstline ***: Two-week moxifloxacin-containing triple therapy showed better efficacy than a 1-wk regimen after non-bismuth quadruple therapy *** words: Helicobacter pylori; Moxifloxacin-based triple; Non-bismuth quadruple; Second-line;

关键词： Helicobacter pylori Moxifloxacin-based triple Non-

Breakthrough scalable synthesis of anti-coking Cs-Ni/CeO_(x)-Al_(2)O_(3) nanocatalysts for optimal dry reforming performance

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Nano Research 2025年第2期18卷 913-929页

作者： Kyung Hee Oh shin Wook Kang jin Gyu Lee Jung-Il Yang Byung-Hyun Kim Chang Seop Hong ji Chan Park Clean Fuel Research Laboratory Korea Institute of Energy ResearchDaejeon 34129Republic of Korea Department of Chemistry Korea UniversitySeoul 02841Republic of Korea Department of Chemical and Molecular Engineering Hanyang University ERICAAnsan 15588Republic of Korea Energy Engineering University of Science and TechnologyDaejeon 34113Republic of Korea

The dry reforming(DR)reaction is an eco-friendly process for producing synthesis gas(CO,H_(2))from greenhouse gases(CH_(4),CO_(2)).Despite advancements in various nickel(Ni)supported catalysts for this reaction,achieving high catalyst stability against carbon deposition and improving conversion rates remain significant *** this paper,we introduce a novel approach for synthesizing uniform Ni nanocatalysts with cesium(Cs)and cerium oxide(CeO_(x)).This synthesis is achieved using an automated device based on a co-melt infiltration *** method addresses the limitations of conventional catalyst synthesis,such as complex procedures,low reproducibility,and difficulties in scaling *** resulting catalysts contain uniformly small Ni particles,approximately 5 nm in size,with Cs and CeO_(x) evenly distributed throughout the alumina(Al_(2)O_(3))*** developed Ni/CeO_(x)-Al_(2)O_(3) and Cs Ni/CeOx-Al_(2)O_(3) nanocatalysts demonstrate improved conversion performance and stability under various DR *** improvement is attributed to the synergistic effect of Cs and CeO_(x),which creates a pathway to inhibit and remove carbon ***,these nanocatalysts exhibited superior resistance to carbon deposition compared to conventional Ni/Al_(2)O_(3) and commercial Ni catalysts under identical reaction conditions.

关键词： co-melt infitration nanocatalyst promoter dry reforming reaction coke resistance

Influence of undissolved second-phase particles on dynamic recrystallization behavior of Mg–7Sn–1Al–1Zn alloy during low-and high-temperature extrusions

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Journal of Materials Science & Technology 2021年第12期71卷 87-97页

作者： Hyun ji Kim Sang-cheol jin Jae-Gil Jung Sung Hyuk Park School of Materials Science and Engineering Kyungpook National UniversityDaegu41566Republic of Korea Implementation Research Division Korea Institute of Materials ScienceChangwon51508Republic of Korea

This study investigates the effects of fine and coarse undissolved particles in a billet of the Mg–7 Sn–1 Al–1 Zn(TAZ711)alloy on the dynamic recrystallization(DRX)behavior during hot extrusion at low and high temperatures and the resultant microstructure and mechanical properties of the *** this end,partially homogenized(PH)and fully homogenized(FH)billets are extruded at temperatures of250 and 450°*** PH billet contains fine and coarse undissolved Mg_(2) Sn particles in the interdendritic region and along the grain boundaries,*** fine particles(<1μm in size)retard DRX during extrusion at 250°C via the Zener pinning effect,and this retardation causes a decrease in the area fraction of dynamically recrystallized(DRXed)grains of the extruded *** addition,the inhomogeneous distribution of fine particles in the PH billet leads to the formation of a bimodal DRXed grain structure with excessively grown grains in particle-scarce *** contrast,in the FH billet,numerous nanosized Mg_(2) Sn precipitates are formed throughout the material during extrusion at 250°C,which,in turn,leads to the formation of small,uniform DRXed grains by the grain-boundary pinning effect of the *** the PH billet is extruded at the high temperature of 450°C,the retardation effect of the fine particles on DRX is weakened by their dissolution in theα-Mg matrix and the increased extent of thermally activated grain-boundary *** contrast,the coarse Mg_(2) Sn particles in the billet promote DRX during extrusion through the particle-stimulated nucleation phenomenon,which results in an increase in the area fraction of DRXed *** both low and high extrusion temperatures,the extruded material fabricated using the PH billet,which contains both fine and coarse undissolved particles,has a lower tensile strength than that fabricated using the FH billet,which is virtually devoid of second-phase *** lower strength of the former is attributed mai

关键词： Mg–Sn alloy Second-phase particle Extrusion Homogenization Dynamic recrystallization

Quantitative volumetric analysis of the optic radiation in the normal human brain using diffusion tensor magnetic resonance imaging-based tractography

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Neural Regeneration Research 2014年第3期9卷 280-284页

作者： Dong-Hoon Lee ji-Won Park cheol-Pyo Hong Center for Medical Metrology Division of Convergence Technology Korea Research Institute of Standards and Science (KRISS) Department of Radiological Science College of Health Science Yonsei University Department of Physical Therapy College of Medical Science Catholic University of Daegu

To attain the volumetric information of the optic radiation in normal human brains, we per- formed diffusion tensor imaging examination in 13 healthy volunteers. Simultaneously, we used a brain normalization method to reduce individual brain variation and increase the accuracy of volumetric information analysis. In addition, tractography-based group mapping method was also used to investigate the probability and distribution of the optic radiation pathways. Our results showed that the measured optic radiation fiber tract volume was a range of about 0.16% and that the fractional anisotropy value was about 0.53. Moreover, the optic radiation probability fiber pathway that was determined with diffusion tensor tractography-based group mapping was able to detect the location relatively accurately. We believe that our methods and results are help- ful in the study of optic radiation fiber tract information.

关键词： nerve regeneration optic radiation diffusion tensor imaging diffusion tensor tractogra-phy magnetic resonance imaging volumetric analysis probability map group mapping visualiza-tion individual variation neural regeneration

Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides

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Acta Pharmaceutica Sinica B 2016年第4期6卷 352-358页

作者： Tingting Lin Ergang Liu Huining He Meong cheol shin cheol Moon Victor C.Yang Yongzhuo Huang Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnosis School of Pharmacy Tianjin Medical University Shanghai Institute of Materia Medica Chinese Academy of Sciences College of Pharmacy The University of Michigan College of Pharmacy and Research Institute of Pharmaceutical Sciences Gyeongsang National University College of Pharmacy Sunchon National University

Brain delivery of macromolecular therapeutics (e.g., proteins) remains an unsolved problem because of the formidable blood brain bather (BBB). Although a direct pathway of nose-to-brain transfer provides an answer to circumventing the BBB and has already been intensively investigated for brain delivery of small drugs, new challenges arise for intranasal delivery of proteins because of their larger size and hydrophilicity. h order to overcome the bathers and take advantage of available pathways (e.g., epithelial tight junctions, uptake by olfactory neurons, transport into brain tissues, and intra-brain diffusion), a low molecular weight protamine (LMWP) cell-penetrating peptide was utilized to facilitate nose-to-brain transport. Cell-penetrating peptides (CPP) have been widely used to mediate macromolecular delivery through many kinds of biobarriers. Our results show that conjugates of LMWP proteinsare able to effectively penetrate into the brain after intranasal administration. The CPP-based intranasal method highlights a promising solution for protein therapy of brain diseases. (C) 2016 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

关键词： Intranasal protein delivery Brain targeting Cell-penetrating peptide Low molecular weigh protamine Blood brain barrier

The diluted atropine for inhibition of myopia progression in Korean children

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International Journal of Ophthalmology(English edition) 2018年第10期11卷 1657-1662页

作者： ji-Sun Moon Sun Young shin Department of Ophthalmology National Medical Center Department of Ophthalmology and Visual Science Seoul St.Mary's Hospital College of Medicine the Catholic University of Korea

AIM：To evaluate the efficacy and safety of three different concentrations of diluted atropine for the control of myopia in Korean children,and to assess the risk factors associated with rapid myopia ***：A total of 285 children,with refractive errors within the range of-6 diopters（D）between 5 and 14 years of age were *** using 0.01%,or 0.025%,or 0.05% atropine,for about 1y,changes in refraction,axial lengths and frequency of adverse events were *** regression analyses were performed to evaluate the risk factors associated with rapid myopia ***：The changes in the mean spherical equivalent values were -0.134 D/mo in the before atropine group,-0.070 D/mo in the 0.01% atropine group,-0.047 D/mo in the 0.025% atropine group,and -0.019 D/mo in the 0.05% atropine group,with significant differences between the groups（P〈0.001）.The axial elongation was 0.046 mm/mo,0.037 mm/mo,0.025 mm/mo,and 0.019 mm/mo respectively,with significant differences between the groups（P=0.003）.The incidence of photophobia and near vision difficulty was not different among the three atropine groups（P=0.425and P=0.356,respectively）.Multivariate logistic regression analyses showed that only highly myopic parents were a significant predictive factor of rapid myopia progression in Korean children（odds ratio,8.155;95% confidence interval,3.626-18.342;P〈0.001）.CONCLUSION：Treatment with 0.01%,0.025% and 0.05% atropine solution inhibits myopia progression in Korean children in a dose-dependent *** with highly myopic parents preferentially shows a rapid myopia progression rate.

关键词： atropine Korean children myopia progression