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Frontiers of Materials Science 2019年第4期13卷 389-398页

作者： Kaushik DAS C.A.KUMAR Leonardo MIRANDOLA Maurizio CHIRIVAJNTERNATI jharna chaudhuri Department of Mechanical Engineering Texas Tech UniversityLubbockTX 79409USA Department of Physics and Astronomy University of Texas at San AntonioSan AntonioTX 78249USA Department of Atomic and Molecular Physics Manipal UniversityManipal 576104KarnatakaIndia Department of Natural and Physical Sciences Northwest Vista College3535 N Ellison DrSan AntonioTX 78251USA Kiromic BioPharma 7707 Fannin St.Suite 140Houston.TX 77054USA Department of Gastroenterology Hepatology and NutritionUniversity of Texas MD Anderson Cancer CenterHoustonTX 77030USA Department of Mechanical and Materials Engineering PO Box 751Portland State UniversityPortlandOR 97207-0751USA

Upconversion nanoparticles(UC NPs)in combination with plasmonic materials have great potential for cancer photothermal ***,sodium holmium fluoride(NaHoF4)is being investigated for luminescence and magnetic resonance imaging(MRI)contrast ***,we present successful synthesis of excellent quality doped NaHoF4 NPs for possible UC luminescence application and coated for possible photothermal therapy *** NaHoF4 nanocrystals were doped with Yb/Er and coated with gold,gold/silica,silver and polypyrrole(PPy).XRD,XPS and TEM were used to determine structure and morphology of the *** UC photoluminescence(PL)emission spectra were obtained from the NPs when excited by near-infrared(NIR)light at 980 *** viability and toxicity of the NPs were characterized using pancreatic and ovarian cancer cells with results showing that gold/silica coating produced least toxicity followed by gold coating.

关键词： photothermal therapy upconversion photoluminescence nanoparticle sodium holmium fluoride

Erratum to: Synthesis and characterization of lanthanide-doped sodium holmium fluoride nanoparticles for potential application in photothermal therapy

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Frontiers of Materials Science 2020年第3期14卷 351-352页

作者： Kaushik Das GAKumar Leonardo Mirandola Maurizio Chiriva-Internati jharna chaudhuri Department of Mechanical Engineering Texas Tech UniversityLubbockTX79409USA Department of Physics and Astronomy University of Texas at San AntonioSan AntonioTX78249USA Department of Atomic and Molecular Physics Manipal UniversityManipal576104KarnatakaIndia Department of Natural and Physical Sciences Northwest Vista College3535 N Ellison DrSan AntonioTX78251USA Kiromic BioPharma 7707 Fannin St.Suite 140HoustonTX77054USA Department of Gastroenterology Hepatology and NutritionUniversity of Texas MD Anderson Cancer CenterHoustonTX77030USA Department of Mechanical and Materials Engineering Portland State UniversityPO Box 751PortlandOR97207-0751USA

The authors did not realize that the presentations of some TEM images were *** versions of such figures and thecorresponding text should be changed as follows.

关键词： lanthanide fluoride characterization

Magnetic and optical properties of NaGdF4：Nd^3＋, Yb^3＋, Tm^3＋ nanocrystals with upconversion/downconversion luminescence from visible to the near-infrared second window

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Nano Research 2015年第2期8卷 636-648页

作者： Xianwen Zhang Zhi Zhao Xin Zhang David B. Cordes Brandon Weeks Bensheng Qiu Kailasnath Madanan Dhiraj Sardar jharna chaudhuri Department of Mechanical Engineering Texas Tech University Lubbock Texas 79409 USA Hefei National Laboratory for Physical Sciences at the Microscale Hefei Anhui 230026 China Department of Chemical Engineering Texas Tech University Lubbock Texas 79409 USA Department of Chemistry & Biochemistry Texas Tech University Lubbock Texas 79409 USA EaStCHEM School of Chemistry University of St. Andrews St. Andrews KY16 9ST UK School of Information Science and Technology University of Science and Technology of China Hefei Anhui 230026 China Department of Physics and Astronomy University of Texas at San Antonio San Antonio Texas 78249 USA International School of Photonics Cochin University of Science and Technology Kochi 682022 India

We have designed and synthesized NaGdF4：Nd^3＋, Yb^3＋, Tm^3＋. magnetic nano- phosphors with combined dual-mode downconversion （DC） and upconversion （UC） photoluminescence upon 800 run excitation. Hexagonal-phase NaGdF4：Nd^3＋, Yb^3＋, Tm^3＋ nanocrystals （NCs） with an average size of 21 nm were synthesized using a solvothermal approach. Nd^3＋, Yb^3＋, Tm^3＋ triple-doped NaGdF4 NCs exhibit a broad range of photoluminescence peaks covering a near infrared first/second window （860-900, 1,000, and 1,060 nm）, and visible emission including blue （475 nm）, green （520 and 542 nm） and yellow （587 nm） after excitation at 800 nm. A mechanism involving circulation of energy over Gd^3＋ sublattices as bridge ions and final trapping by the initial activator ions （Nd^3＋） has been proposed. Penetration depth studies indicate that NIR emission is easily detected even at a large tissue thickness of 10 mm. These paramagnetic nanophosphors demonstrate a large magnetization value of 1.88 emu/g at 20 kOe and longitudinal relaxivity value of 1.2537 mM-1.S-1 as a Tl-weighted magnetic resonance imaging contrast agent. These NaGdF4：Nd^3＋, Yb^3＋ Tm^3＋ NCs are promising for applications in biological and magnetic resonance imaging.

关键词： near-infrared second window photoluminescence energy transfer nanocrystals

Nanofluids:Critical issues,economics and sustainability perspectives

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Particuology 2024年第4期87卷 147-172页

作者： Sayantan Mukherjee Sylwia Wcislik Purna Chandra Mishra Paritosh chaudhuri Instiute for Plasma Research Gandhinagar GujaratIndia Department of Building Physics and Renewable Energy Faculy of Environmental EngineeringGeodesy and Renewable EnergyKielce University of TechnologyAleja Tysiaclecia Panstwa Polskiego 7.25-314 KielcePoland Thermal Research Laboratory(TRL) School of Mechanical Engineering.KIT Deemed to be UniversityBhubaneswarOdishaIndia Homi Bhabha National Instirute(HBNI) AnushaktinagarMumbai 400094India

According to the Scopus database,every year several hundreds of new research papers are published in the field of *** area is attracting growing attention because of the significant improvement in the heat transfer and energy efficiency of the systems working with ***,as results from numerous scientific studies conducted by independent laboratories,there are several fundamental problems related to the unambiguous determination of their physical properties,their production,and economic *** most studies often focus on one issue or cover one kind of research or math-ematical correlation,this review paper provides insights into many problems during nanofluids research by proposing solving possibilities,which is the strength of our *** paper discusses the case of nanofluids quality,and morphology,thermal conductivity enhancement and the discrepancies in mathematical modelling,errors in dimensional and similarity analysis,nanofluid erosion,safety guide-lines,and toxicology ***,the sustainability and economics of nanofluids usage are also being discussed.

关键词： Nanofluids Thermal conductivity Stability Erosion Economics Sustainability

Glucagon-like peptide-1 receptor agonists as a possible intervention to delay the onset of type 1 diabetes:A new horizon

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World Journal of Diabetes 2024年第2期15卷 133-136页

作者： Mahmoud Nassar Ajay chaudhuri Husam Ghanim Paresh Dandona Department of Internal Medicine Division of EndocrinologyDiabetes and MetabolismJacobs School of Medicine and Biomedical SciencesUniversity of BuffaloBuffaloNY 14221United States

Type 1 diabetes(T1D)is a chronic autoimmune condition that destroys insulinproducing beta cells in the pancreas,leading to insulin deficiency and *** management of T1D primarily focuses on exogenous insulin replacement to control blood glucose ***,this approach does not address the underlying autoimmune process or prevent the progressive loss of beta *** research has explored the potential of glucagon-like peptide-1 receptor agonists(GLP-1RAs)as a novel intervention to modify the disease course and delay the onset of ***-1RAs are medications initially developed for treating type 2 *** exert their effects by enhancing glucose-dependent insulin secretion,suppressing glucagon secretion,and slowing gastric *** evidence suggests that GLP-1RAs may also benefit the treatment of newly diagnosed patients with *** article aims to highlight the potential of GLP-1RAs as an intervention to delay the onset of T1D,possibly through their potential immunomodulatory and anti-inflammatory effects and preservation of *** article aims to explore the potential of shifting the paradigm of T1D management from reactive insulin replacement to proactive disease modification,which should open new avenues for preventing and treating T1D,improving the quality of life and long-term outcomes for individuals at risk of T1D.

关键词： Type 1 diabetes Semaglutide Glucagon-like peptide-1 receptor agonists Insulin therapy Autoimmune response Blood glucose monitoring Β-cell preservation Early screening Teplizumab Randomized controlled trials

Dynamic analysis of buried pipeline with and without barrier system subjected to underground detonation

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Defence Technology（防务技术） 2023年第11期29卷 95-105页

作者： Chaidul Haque chaudhuri Deepankar Choudhury Department of Civil Engineering Indian Institute of Technology BombayMumbai400076India

Failure of pipe networks due to blast loads resulting from terrorist attacks or construction facilities, may cause economic loss, environmental pollution, source of firing or even it may lead to a disaster. The present work develops a closed-form solution of buried pipe with barrier system subjected to subsurface detonation. The solution is derived based on the concept of double-beam system. Euler Bernoulli's beams are used to simulate the buried pipe and the barrier system. Soil is idealized as viscoelastic foundation along with shear interaction between discrete Winkler springs(advanced soil model). The finite SineFourier transform is employed to solve the coupled partial differential equations. The solution is validated with past studies. A parametric study is conducted to investigate the influence of TNT charge weight, pipe material, damping ratio and TNT offset on the response of buried pipe with and without barrier system. Further a statistical analysis is carried out to get the significant soil and pipe input parameters. It is perceived that peak pipe displacements for both the cases(with and without barrier) are increases with increasing the weight of TNT charge and decreases with increasing the damping ratio and TNT offset. The deformation of pipe also varies with pipe material. Pipe safety against blast loads can be ensured by providing suitable barrier layer. The present study can be utilized in preliminary design stage as an alternative to expensive numerical analysis or field study.

关键词： Buried pipeline Subsurface detonation Analytical solution Viscoelastic foundation Protective barrier

Design optimization of first wall and breeder unit module size for the Indian HCCB blanket module

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Plasma Science and Technology 2018年第6期20卷 200-210页

作者： Deepak SHARMA Paritosh chaudhuri Institute for Plasma Research Bhat Gandhinagar Gujarat-382428 India

The Indian test blanket module（TBM） program in ITER is one of the major steps in the Indian fusion reactor program for carrying out the R＆D activities in the critical areas like design of tritium breeding blankets relevant to future Indian fusion devices（ITER relevant and DEMO）.The Indian Lead–Lithium Cooled Ceramic Breeder（LLCB） blanket concept is one of the Indian DEMO relevant TBM,to be tested in ITER as a part of the TBM ***-Cooled Ceramic Breeder（HCCB） is an alternative blanket concept that consists of lithium titanate（Li_2TiO_3） as ceramic breeder（CB） material in the form of packed pebble beds and beryllium as the neutron ***,attentions are given to the optimization of first wall coolant channel design and size of breeder unit module considering coolant pressure and thermal loads for the proposed Indian HCCB blanket based on ITER relevant TBM and loading *** analyses will help proceeding further in designing blankets for loads relevant to the future fusion device.

关键词： first wall blanket breeder unit thermal hydraulics structural analysis HCCB(helium-cooled ceramic breeder)

Empirical approaches in prediction of reservoir sediment distribution——An experience of 57 reservoirs in the USA and India

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International Journal of Sediment Research 2017年第2期32卷 260-276页

作者： Dipankar chaudhuri DVC

An accurate prediction of sediment distribution may minimize economic losses through proper and timely planning of the functional activities of a *** study assesses different temporal and spatial factors that affect for sediment deposition in a reservoir and its *** study also focuses on evaluation of two popular distribution prediction methodologies,Area Increment and Empirical Area Reduction,based on experience with sediment distribution in 57 reservoirs in the USA and India.A non-iterative processed empirical distribution model(NPEDM) and a linear regression trend model(LRTM) are proposed to predict sediment *** contributing area and inflow entering a reservoir are found to be the most significant factors affecting in reservoir sediment *** to the Empirical Area Reduction method,the Area Increment method provided better *** reservoir classification approach and empirical design distribution type curves given by Borland and Miller(1960) are found to be *** factor values for different periods indicate that reservoir shape(type) changes with ***,long term prediction is not desirable in Type-Ⅱ & Ⅲ reservoirs using the Empirical Area Reduction *** developed the NPEDM shows reasonably good prediction of sediment *** NPEDM is very easy to apply and can be used in any reservoir of any *** of the trend of sediment distribution obtained from the LRTM indicates an accurate short term prediction in a few reservoirs as causes of temporal and spatial variations of sediment distribution including the factors of uncertainties of sediment deposition are implicit within the methodology.

关键词： Deposition factors Temporal and spatial variations Trend projection Model performance Type curve Relative depth

Comparative studies for two different orientations of pebble bed in an HCCB blanket

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Plasma Science and Technology 2017年第12期19卷 146-153页

作者： Paritosh chaudhuri Chandan DANANI E RAJENDRAKUMAR Institute for Plasma Research BhatGandhinagar-382 428India

The Indian Test Blanket Module（TBM） program in ITER is one of the major steps in its fusion reactor program towards DEMO and the future fusion power reactor vision. Research and development（RD） is focused on two types of breeding blanket concepts： lead–lithium ceramic breeder（LLCB） and helium-cooled ceramic breeder（HCCB） blanket systems for the DEMO reactor. As part of the ITER-TBM program, the LLCB concept will be tested in one-half of ITER port no. 2, whose materials and technologies will be tested during ITER operation. The HCCB concept is a variant of the solid breeder blanket, which is presently part of our domestic RD program for DEMO relevant technology development. In the HCCB concept Li_2TiO_3 and beryllium are used as the tritium breeder and neutron multiplier, respectively, in the form of a packed bed having edge-on configuration with reduced activation ferritic martensitic steel as the structural material. In this paper two design schemes, mainly two different orientations of pebble beds, are discussed. In the current concept（case-1）, the ceramic breeder beds are kept horizontal in the toroidal–radial direction. Due to gravity, the pebbles may settle down at the bottom and create a finite gap between the pebbles and the top cooling plate, which will affect the heat transfer between them. In the alternate design concept（case-2）, the pebble bed is vertically（poloidal–radial） orientated where the side plates act as cooling plates instead of top and bottom plates. These two design variants are analyzed analytically and 2 D thermal-hydraulic simulation studies are carried out with ANSYS, using the heat loads obtained from neutronic *** on the analysis the performance is compared and details of the thermal and radiative heat transfer studies are also discussed in this paper.

关键词： fusion reactor test blanket module HCCB thermal radiation heat transfer

DEM modeling of high shear wet granulation of a simple system

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Asian Journal of Pharmaceutical Sciences 2018年第3期13卷 220-228页

作者： Saurabh Sarkar Bodhisattwa chaudhuri Department of Pharmaceutical Sciences University of Connecticut Institute of Material Sciences University of Connecticut

High shear wet granulation(HSWG) is one of the most poorly understood processes with known difficulties in optimization and scale up. The purpose of the current study is to develop a DEM model which can be applied under dynamic process conditions with high predictive capacity to improve process insight. The DEM model is used to predict agglomeration as a function of impeller speed and liquid addition rate in a high shear wet granulator. The DEM model tracks dynamic formation and breakage of liquid bridges between particles as liquid binder in the system is added, and corrects for the change in material properties as a function of the binder content.

关键词： High shear wet granulation Discrete element method Capillary bridge model