检索结果-南通市图书馆

The Periaqueductal Gray and Its Extended Participation in Drug Addiction Phenomena

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Neuroscience Bulletin 2021年第10期37卷 1493-1509页

作者： Priscila Vazquez-Leon Abraham Miranda-Paez jesus chavez-reyes Gonzalo Allende Paulino Barragan-Iglesias Bruno A.Marichal-Cancino Departamento de Fisiologia y Farmacologia Centro de Ciencias BasicasUniversidad Autonoma de AguascalientesCiudad Universitaria20131 AguascalientesAgs.Mexico Departamento de Fisiologia Escuela Nacional de Ciencias BiologicasInstituto Politecnico NacionalWilfrido Massieu esq.Manuel Stampa s/n Col.Nueva Industrial Vallejo07738 Gustavo A.MaderoMexico CityMexico

The periaqueductal gray(PAG)is a complex mesencephalic structure involved in the integration and execution of active and passive self-protective behaviors against imminent threats,such as immobility or flight from a predator.PAG activity is also associated with the integration of responses against physical discomfort(e.g.,anxiety,fear,pain,and disgust)which occurs prior an imminent attack,but also during withdrawal from drugs such as morphine and cocaine.The PAG sends and receives projections to and from other well-documented nuclei linked to the phenomenon of drug addiction including:(i)the ventral tegmental area;(ii)extended amygdala;(iii)medial prefrontal cortex;(iv)pontine nucleus;(v)bed nucleus of the stria terminalis;and(vi)hypothalamus.Preclinical models have suggested that the PAG contributes to the modulation of anxiety,fear,and nociception(all of which may produce physical discomfort)linked with chronic exposure to drugs of abuse.Withdrawal produced by the major pharmacological classes of drugs of abuse is mediated through actions that include participation of the PAG.In support of this,there is evidence of functional,pharmacological,molecular.And/or genetic alterations in the PAG during the impulsive/compulsive intake or withdrawal from a drug.Due to its small size,it is difficult to assess the anatomical participation of the PAG when using classical neuroimaging techniques,so its phys-iopathology in drug addiction has been underestimated and poorly documented.In this theoretical review,we discuss the involvement of the PAG in drug addiction mainly via its role as an integrator of responses to the physical discomfort associated with drug withdrawal.

关键词： Periaqueductal gray Reward circuit Antireward circuit Alcohol Caffeine Cannabis Opioids Stimulants

Context-dependent insect predation pressure on an avian ectoparasite

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Insect Science 2023年第6期30卷 1784-1797页

作者： Angela Salido Jesús Veiga Joaquín Luis reyes-López Francisco Valera Department of Botany Ecology and Plant PhysiologyUniversity of CórdobaCórdobaSpain Departamento de Ecología Funcional y Evolutiva Estación Experimental de ZonasÁridas(EEZA-CSIC)AlmeríaSpain Department of Parasitology University of GranadaGranadaSpain MEMEG Department of BiologyLund UniversityLundSweden

Context dependence arises when ecological relationships vary with the conditions under which they are observed. Context dependence of interactions involving parasites is poorly known, even if it is key to understanding host–parasite relationships and food web dynamics. This paper investigates to which extent predation pressure on an avian ectoparasite (Carnus hemapterus) is context-dependent. Based on a predator-exclusion experiment, predation pressure on C. hemapterus pupae in the host's nest for 3 years, and its variation between habitat types are quantified. Variation in precipitation and normalized difference vegetation index (NDVI) is also explored as a likely cause of context dependency. We hypothesize that predation pressure should fluctuate with such surrogates of food availability, so that inter-annual and intra-annual differences may emerge. The number of nests with significant reduction of pupae varied widely among years ranging from 24% to 75%. However, average pupae reduction in nests where a significant reduction occurred did not vary between years. No differences in predation rates between habitat types were detected. Precipitation and NDVI varied widely between years and NDVI was consistently lower around nests on cliffs than around nests on trees and farmhouses. Parallels were found between variation in predation pressure and precipitation/NDVI at a wide scale (highest predation the driest year, and much lower the 2 rainier ones), but not at the nest scale. This paper shows clear context-dependent insect predation pressure on an ectoparasite under natural conditions, and that such interaction changes in signs rather than magnitude between years. The causes for these variations require longer-term studies and/or well-designed, large-scale experiments.

关键词： ants arid areas Carnus hemapterus consumer-resource interaction ecosys-tem productivity predator-parasite rainfall

Surgical treatment of acute cholecystitis in patients with confirmed COVID-19:Ten case reports and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Clinical Cases 2022年第4期10卷 1296-1310页

作者： Katya Bozada-Gutierrez Mario Trejo-Avila Fatima chavez-Hernandez Sara Parraguirre-Martinez Carlos Valenzuela-Salazar jesus Herrera-Esquivel Mucio Moreno-Portillo Department of General and Endoscopic Surgery Hospital General Dr.Manuel Gea GonzalezMexico City 14090Mexico Department of Pathology Hospital General Dr.Manuel Gea GonzalezMexico City 14090Mexico

BACKGROUND Research concerning postoperative outcomes of confirmed coronavirus disease 2019(COVID-19)patients revealed unfavorable postoperative results with increased morbidity,pulmonary complications and mortality.Case reports have suggested that COVID-19 is associated with more aggressive presentation of acute cholecystitis.The aim of the present study is to describe the perioperative assessment and postoperative outcomes of ten patients with confirmed severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection with concomitant acute cholecystitis who underwent cholecystectomy.CASE SUMMARY We report a total of 10 SARS-CoV-2 positive patients with concomitant acute cholecystitis that underwent cholecystectomy.Six patients were males,the mean age was 47.1 years.Nine patients had moderate acute cholecystitis,and one patient had severe acute cholecystitis.All patients were treated with urgent/early laparoscopic cholecystectomy.Regarding the Parkland grading scale,two patients received a Parkland grade of 3,two patients received a Parkland grade of 4,and six patients received a Parkland grade of 5.Eight patients required a bail-out procedure.Four patients developed biliary leakage and required endoscopic retrograde cholangiopancreatography with biliary sphincterotomy.After surgery,five patients developed acute respiratory distress syndrome(ARDS)and required intensive care unit(ICU)admission.One patient died after cholecystectomy due to ARDS complications.The mean total length of stay(LOS)was 18.2 d.The histopathology demonstrated transmural necrosis(n=5),vessel obliteration with ischemia(n=3),perforation(n=3),and acute peritonitis(n=10).CONCLUSION COVID-19 patients with acute cholecystitis had difficult cholecystectomies,high rates of ICU admission,and a prolonged LOS.

关键词： COVID-19 SARS-CoV-2 Cholecystectomy in COVID-19 Acute cholecystitis in COVID-19 Case report

Higher cardiovascular risk scores and liver fibrosis risk estimated by biomarkers in patients with metabolic-dysfunction-associated fatty liver disease

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Hepatology 2022年第8期14卷 1633-1642页

作者： Giovanni Alejandro Salgado Alvarez Samanta Mayanin Pinto Galvez Uriel Garcia Mora Ana Delfina Cano Contreras Cristina Durán Rosas Bryan Adrián Priego-Parra Arturo Triana Romero Mercedes Amieva Balmori Federico Roesch Dietlen Sophia Eugenia Martinez Vazquez Ines Osvely Mendez Guerrero Luis Alberto Chi-Cervera Raúl Bernal reyes Leonardo Alberto Martinez Roriguez Maria Eugenia Icaza chavez Jose Maria Remes Troche Instituto de Investigaciones Médico-biologicas Universidad VeracruzanaVeracruz 91700VeracruzMexico Department of Gastroenterología Instituto Nacional de Ciencias Médicas y Nutrición Salvador ZubiránMéxico 14080MéxicoMexico Clínica de Especialidades Gastrointestinales y Hepáticas Hospital Star MedicaMerida 97133YucatanMexico Department of Gastroenterologia Sociedad Española de BeneficenciaPachuca 42000HidalgoMexico Department of Gastroenterologia Clínica de Rehabilitación Metabólica Digestiva y HepáticaMexico 14080MexicoMexico Department of Gastroenterologia Hospital Star Médica de MéridaMerida 97133YucatanMexico

BACKGROUND The definition of metabolic-dysfunction-associated fatty liver disease(MAFLD)allows identification of metabolically complicated patients.Fibrosis risk scores are related to cardiovascular risk(CVR)scores and could be useful for the identification of patients at risk of systemic complications.AIM To evaluate the relationship between MAFLD and CVR using the Framingham risk score in a group of Mexican patients.METHODS Cross-sectional,observational and descriptive study carried out in a cohort of 585 volunteers in the state of Veracruz with MAFLD criteria.The risk of liver fibrosis was calculated with aspartate aminotransferase-to-platelet ratio index,nonalcoholic fatty liver disease score and fibrosis-4,as well as with transient hepatic elastography with Fibroscan~?.The CVR was determined by the Framingham system.RESULTS One hundred and twenty-five participants(21.4%)with MAFLD criteria were evaluated,average age 54.4 years,63.2%were women,body mass index 32.3 kg/m~2.The Framingham CVR was high in 43 patients(33.9%).Transient elastography was performed in 55.2%of volunteers;39.1%with high CVR and predominance in advanced fibrosis(F3–F4).The logistic regression analysis showed that liver fibrosis,diabetes and hypertension independently increased CVR.CONCLUSION One of every three patients with MAFLD had a high CVR,and in those with high fibrosis risk,the CVR risk was even greater.

关键词： Fatty liver Cardiovascular risk Hepatic steatosis Fibrosis Liver disease

Perinuclear anti-neutrophil cytoplasmic antibodies (p-anca) in chronic ulcerative colitis: Experience in a Mexican institution

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第21期12卷 3406-3409页

作者： jesus K Yamamoto-Furusho Takeshi Takahashi-Monroy Omar Vergara-Fernandez Edgardo reyes Luis Uscanga Departments of Gastroenterology. Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Mexico City Mexico Departments of Surgery. Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Mexico City Mexico Departments of Pathology. Institute Nacional de Ciencias Medicas y Nutricion Salvador Zubiran Mexico City Mexico

瞄准：在墨西哥 ulcerative (UC ) 的一件样品估计流行和 p-ANCA 的临床的价值病人。方法：在一个未来的、同意 IRB 的协议， p-ANCA 与 UC 在 80 个病人被决定(吝啬的年龄， 32 +/- 12.9 年) 。疾病的严厉和延期被临床的方法决定，寻找... 详细信息

瞄准：在墨西哥 ulcerative (UC ) 的一件样品估计流行和 p-ANCA 的临床的价值病人。方法：在一个未来的、同意 IRB 的协议， p-ANCA 与 UC 在 80 个病人被决定(吝啬的年龄， 32 +/- 12.9 年) 。疾病的严厉和延期被临床的方法决定，寻找有 p-ANCA 地位的一个统计协会。结果：p-ANCA 在 41 被检测(51%) 病人。疾病的严厉是统计上与他们的存在联系的唯一的临床的变量(P < 0.0001；或 = 9；CI 95%= 3.2-24.7 ) 。结论：p-ANCA 的流行类似于在另外的国家报导了那。他们的存在被联系到 UC 严厉，但是比提供了没有更多的信息由临床的方法获得了。

关键词：细胞周期抗中性细胞抗体大肠溃疡墨西哥

A Sustainable Agriculture Production Model of Pampanga State Agricultural University in Central Luzon, Philippines

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Agricultural Science and Technology(A) 2015年第8期5卷 671-677页

作者： Norman De jesus Honorio Soriano Jr Rafael Rafael Emmanuel Pangilinan Cesar Orpiada Estrella Zabala Regina Loria Ernesto Supan Filomena reyes Celso reyes Angelina De jesus College of Agriculture Systems and Technology (CAST) Pampanga State Agricultural University (PSA U) Magalang Pampanga2011 Philippines College of Arts and Sciences (CAS) Pampanga State Agricultural University Magalang Pampanga 2011 Philippines Alternative Low-Input Agriculture Systems (ALIAS) Center Pampanga State Agricultural University Magalang Pampanga 2011Philippines College of Home Economics and Food Sciences (CHEFS) Pampanga State Agricultural University Magalang Pampanga 2011Philippines College of Education (COEd) Pampanga State Agricultural University Magalang Pampanga 2011 Philippines

Insulin sensitizers in treatment of nonalcoholic fatty liver disease:Systematic review

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第48期12卷 7826-7831页

作者： Norberto C chavez-Tapia Tonatiuh Barrientos-Gutierrez Felix I Tellez-ávila Francisco Sánchez-ávila Maria Antonieta Montao-reyes Misael Uribe Department of Gastroenterology Instituto Nacional de Ciencias Médicas y Nutrición Zalvador Zubirán Mexico City Mexico The University of Texas School of Public Health Houston United States Instituto de Educación Media Superior Mexico City Mexico

AIM: To summarize the evidence available for the clinical effectiveness of insulin sensitizers in the treatment of nonalcoholic fatty liver disease (NAFLD) systematically. METHODS: Relevant articles were located using computer-assisted searches of Medline (1966-March 2006), EMBASE (1988-March 2006), CINAHL (1982-March 2003), Educational Resource Information Center (1966-March 2006), Library, Information Science & Technology Abstracts (1967-March 2006), Cochrane Database of Systematic Reviews, Database of Abstracts of Reviews of Effects (1994-2006), dissertations in ProQuest and FirstSearch databases. Manual searches were made in the abstracts from meetings of the American Gastroenterological Association (1999-2006), and the American Association for the Study of Liver Diseases (2003-2005). Studies were retrieved using the following selection criteria: (1) clinical trials using insulin sensitizers in subjects with NAFLD, (2) adult patients, (3) published as full manuscripts or abstracts, and (4) English, Spanish, German, and French languages only. Data were abstracted independently by two reviewers following standardized procedures. A face-to- face comparison of data was conducted to ensure the completeness and reliability of the abstraction process. RESULTS: Nine studies were included, six using metformin and three using thiazolidinediones. Only two studies were placebo-controlled trials. The mediansample size for all studies was 18 subjects. In the placebo-controlled trials, metformin improved insulin resistance markers and liver function tests, but not histological scores. In the single-arm trials, metformin and thiazolidinediones improved insulin resistance markers and liver function tests, and beneficial histological changes were reported. There is limited high-quality information available from which to draw categorical conclusions about the clinical use of insulin sensitizers in NAFLD.CONCLUSION: Current information indicates that the use of insulin sensitizers in NAFLD improves insulin resistance and liver

关键词：敏化剂治疗非酒精性脂肪肝病理

Synthesis of ZnS:Tm<sup>3+</sup>Nanoparticles by the Polyol Method

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Applied Sciences 2019年第7期9卷 613-619页

作者： Francisco jesus Rodriguez Joan reyes Dulce Y. Medina Miguel Angel Barron Catalina Haro-Perez Ciencias Básicas e Ingeniería Universidad Autónoma Metropolitana Mexico City México

In this work, the synthesis of undoped and Tm-doped ZnS nanoparticles is successfully carried out by the polyol method. From XRD analyses, it was confirmed that both types of particles possess the cubic zinc blend structure of the ZnS, and that the structure is not altered by doping. The crystallite size computed by the Scherrer equation is about 9 ± 1 nm. From photoluminescence analyses, the results show that the excitation spectrum has two excitation peaks at 304 nm and 356 nm;by exciting at 304 nm, a strong blue emission is observed at 420 nm, while exciting at 356 nm the characteristic Tm transition 1G4 → 3H6 is observed at 417 nm. By doping with Tm ions, the emission color changes from pure blue to sky according to the change in CIE coordinates from x = 0.15, y = 0.015 to x = 0.18, y = 0.17, respectively.

关键词： Luminescence Zinc Sulfide Blue Emission

Synthesis of Tenoltrifluoroacetone Composite Doped with Terbium, Dysprosium and Europium Encapsulated in Silica Oxide Matrix

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Surface Engineered Materials and Advanced Technology 2020年第4期10卷 63-74页

作者： Yazmin Francisco Dulce Medina Miguel Barron Joan reyes Pedro Adrian Martinez Angel de jesus Morales Elizabeth Garfias Universidad Autónoma Metropolitana Departamento de Materiales Ciencias Básicas e Ingeniería Reynosa Tamaulipas México Instituto Politécnico Nacional ESIQIE UPALM S/N Mexico City México

The synthesis of the thenoyltrifluoroacetone compound doped with terbium, dysprosium and europium encapsulated in a silica matrix (TTA:Tb:Dy:Eu@SiO2) were performed by the sol-gel method. The precursors to obtain the vitreous phase (SiO2) were: Tetraethylorthosilicate (TEOS, C8H2O4Si, 98%, Aldrich), and ethyl alcohol (CH3CH2OH, 99.5%, Meyer), distilled water and 0.05 ml of hydrochloric acid (HCl, Meyer). The sample with molar ratio 20:80 TTA:Tb:Dy:Eu@SiO2 has the best emission intensity. Thermogravimetric analysis (TGA) shown that silica encapsulated samples decompose at lower temperatures than pure TTA:Tb:Dy:Eu luminescent material. Fourier Transform Infrared (IR-TF) shown the characteristic Si-O-Si bands that are presented at a wavelength of 1049, 853 and 440 cmǃ confirming that the luminescent material is encapsulated in a silica matrix, finally X-ray diffraction (XRD) shown that TTA:Tb:Dy:Eu@SiO2 composite is amorphous.

关键词： Synthesis Luminescence Composite Sol-Gel Terbium Dysprosium and Europium