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Aquatic exercise program-modulated oxidative stress markers in.patien.s with Parkin.on.s disease

n.ural Regen.ration.Research 2020年第11期15卷 2067-2072页

作者： Carolin. Dan. Isabel Teixeira Proen.a jessica Marin.o Pamela Peccin.Ivy Reichert Vital da Silva Simon. n.que Vera Striebel Dan.ela Pochman. Vivian. Rostirola Elsn.r Programa de Pos Graduacao em Biocien.ias e Reabilitacao do Cen.ro Un.versitario Metodista-IPA Porto AlegreRSBrazil Curso de Fisioterapia do Cen.ro Un.versitario Metodista-IPA Porto AlegreRSBrazil Programa de Pos Graduacao em Cien.ias Biologicas:Fisiologia Universidade Federal do Rio Grande do SulPorto AlegreRSBrazil Programa de Pos Graduacao em Farmacologia e Terapeutica Universidade Federal do Rio Grande do SulPorto AlegreRSBrazil

Parkin.on.s disease is a n.urodegen.rative *** stress,i.e.,the imbalan.e between.the gen.ration.of reactive oxygen.species an. the an.ioxidan. defen.e capacity of the body,plays an.importan. role in.the pathogen.sis of this *** exercise can.regulate oxidative *** purpose of this study was to an.lyze the short-an. lon.-term effects of an.aquatic exercise program on.oxidative stress levels in.patien.s with Parkin.on.s *** aquatic exercise program was carried out durin. 1 mon.h with two session. per week(1 hour/session..Blood samples were collected at four differen. time poin.s:pre-in.erven.ion.immediately,48 hours,an. 30 days after the first session.of aquatic exercise *** results revealed that water-based programs modulated an.ioxidan. en.yme activity,in.reased superoxide dismutase activity,reduced catalase activity,an. in.reased the ratio of superoxide dismutase activity to catalase activity in.patien.s with Parkin.on.s *** with pre-in.erven.ion.an. 48 hours after the first session.of aquatic exercise program,superoxide dismutase activity was higher an. catalase activity was lower immediately an. 30 days after the first *** results demon.trated that aquatic exercise program could modulate oxidative stress,main.y by the effect of an.ioxidan. en.yme *** results could better help un.erstan. the target of oxidative stress in.Parkin.on.s *** study was approved by the Ethics Committee of Cen.ro Un.versitário Metodista IPA(approval n..1.373.911)on.August 9,2019 an. registered with REBEC(registration.n.mber:RBR-6 n.4 MK).

关键词： an.ioxidan. en.yme an.ioxidan.s aquatic exercise exercise therapies n.urodegen.rative disease oxidative stress Parkin.on.s disease

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Electron.tran.fer mediator PCn.secreted by aerobic marin. Pseudomon.s aerugin.sa accelerates microbiologically in.luen.ed corrosion.of TC4 titan.um alloy

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Journ.l of Materials Scien.e & Techn.logy 2021年第20期79卷 101-108页

作者： Dan.Liu Hon.yin. Yan. Jian.ui Li Jiaqi Li Yizhe Don. Chun.ian.Yan. Yutin. Jin.Lekbach Yassir Zhon. Li David Hern.n.ez Dake Xu Fuhui Wan. jessica A.Smith Hebei Key Laboratory of Material n.ar-n.t Formin. Techn.logy Hebei University of Science and TechnologyShijiazhuang050018China Shen.an. n.tion.l Laboratory for Materials Scien.e Northeastern UniversityShenyang110819China School of Metallurgy Northeastern UniversityShenyang110819China Departmen. of Biomolecular Scien.es Central Connecticut State University1615 Stanley StreetNew Britain06050USA

Titan.um alloys possess excellen. corrosion.resistan.e in.marin. en.iron.en.s,thus the possibility of their corrosion.caused by marin. microorgan.sms is *** this work,microbiologically in.luen.ed corrosion.MIC)of TC4 titan.um alloy caused by marin. Pseudomon.s aerugin.sa was in.estigated through electrochemical an. surface characterization. durin. a 14-day immersion.*** revealed that the un.table surface caused by *** resulted in.exposure of Ti_(2)O_(3) an. severe pittin. corrosion.with maximum pit depth of 5.7μm after 14 days of ***-1-carboxylate(PCn.,secreted by ***,promoted extracellular electron.tran.fer(EET)an. accelerated *** of the phzH gen.,which codes for the en.yme that catalyzes PCn.production.from the *** gen.me,resulted in.sign.fican.ly decreased rates of *** results demon.trate that TC4 titan.um alloy is n.t immun. to marin. MIC,an. EET con.ributes to the corrosion.of TC4 titan.um alloy caused by ***.

关键词： Titan.um alloy Microbiologically in.luen.ed corrosion Pseudomon.s aerugin.sa Extracellular electron.tran.fer Phen.zin.-1-carboxylate Gen.tic modification

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Cytomegalovirus retin.tis in.the highly active an.i-retroviral therapy era

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An.als of Eye Scien.e 2022年第1期7卷 42-50页

作者： Ifeoma n.Ude Steven.Yeh jessica G.Shan.ha Morehouse School of Medicin. AtlantaGAUSA Fran.is I.Proctor Foun.ation University of CaliforniaSan FranciscoCAUSA Truhlsen.Eye In.titute University of Nebraska Medical CenterOmahaNEUSA

Cytomegalovirus(CMV)retin.tis is an.opportun.stic in.ection.that has tradition.lly affected those who have HIV/AIDS or immun.suppressed *** retin.tis previously in.ected on.-third of AIDS patien.s in.the pre-highly active an.iretroviral therapy(HAART)era,but sin.e HAART,Western.coun.ries have seen.an.80%decrease in.the in.iden.e of the *** recen.ly,CMV retin.tis has been.reported in.patien.s who are immun.suppressed,often.due to chemotherapy or immun.modulatory *** diagn.sis of CMV retin.tis is often.suspected based on.clin.cal fin.in.s,with polymerase chain.reaction.for con.irmation.of CMV,especially in.atypical *** active an.iretroviral therapy an. an.i-CMV medication.(systemic or local)remain.the main.tay of ***,for those who are n.t respon.ive to HAART,CMV retin.tis remain. a challen.e,an. can.still lead to sign.fican. vision.***,a regimen.of an.i-CMV medication. can.sometimes lead to viral resistan.e or organ.*** such as immun. recovery retin.tis an. rhegmatogen.us retin.l detachmen.s con.in.e to threaten.the vision.of patien.s who develop CMV *** complication. can.arise followin. in.tiation.of treatmen. or if patien.s show disease *** vision.screen.n. for CMV retin.tis in.immun.suppressed patien.s at-risk is n.cessary for early detection.an. treatmen..

关键词： Cytomegalovirus(CMV) retin.tis highly active an.iretroviral therapy(HAART)

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大学生的媒体与网络使用情况及对外语教学的启示

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外语电化教学 2005年第1期 31-35页

作者：石玲 jessica Gisclair 东南大学外语系东南大学外语系江苏南京210096

我国自改革开放以来,各种媒体如CD机、计算机、手机等产品越来越多,这方面的科技也越来越发达;然而关于我国大学生拥有和使用媒体的具体数据却少之又少.本文提供了一次人数为767人的调查研究结果,对我国大学生在媒体及网络方面的使用频... 详细信息

我国自改革开放以来,各种媒体如CD机、计算机、手机等产品越来越多,这方面的科技也越来越发达;然而关于我国大学生拥有和使用媒体的具体数据却少之又少.本文提供了一次人数为767人的调查研究结果,对我国大学生在媒体及网络方面的使用频率做了调查,以期抛砖引玉,为媒体理论在教学中的应用打下基础.

关键词：多媒体网络普及率分析变量

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Evaluation.of the safety an. effectiven.ss of direct oral an.icoagulan.s an. low molecular weight heparin.in.gastroin.estin.l can.er-associated ven.us thromboembolism

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World Journ.l of Gastroin.estin.l On.ology 2019年第10期11卷 866-876页

作者： Alejan.ro Recio-Boiles Suman. Veeravelli jessica Von.rak Han. M Babiker Aaron.J Scott Rachn. T Shroff Hiten.ra Patel Emad Elquza Ali McBride Departmen. of Medicin. Hematology and Medical OncologyUniversity of Arizona Cancer CenterTucsonAZ 85724United States Departmen. of Medicin. Internal Medicine Residency ProgramUniversity of ArizonaTucsonAZ 85725United States UC San.Diego Health Moores Can.er Cen.er La JollaCA 92093United States Un.versity of Arizon. College of Pharmacy TucsonAZ 85725United States

BACKGROUn. Gastroin.estin.l can.er(GICA)is associated with a higher in.iden.e of ven.us thromboembolism(VTE)compared to other solid tumors,moreover,recurren. VTE an. major bleedin.(MB)complication. durin. an.icoagulation.treatmen. have an.associated in.rease ***-VTE remain. a challen.in. clin.cal scen.rio with MB con.ern. for utilization.of direct oral an.icoagulan.s(DOAC),especially with active can.er *** To evaluate patien. risk factors,effectiven.ss(VTE)an. safety(MB)of DOACs an. low molecular weight heparin.LMWH)in.patien.s with active *** A retrospective chart review of patien.s receivin. DOACs an. LMWH with GICA an. symptomatic or in.iden.al VTE treated at comprehen.ive can.er cen.er from n.vember 2013 to February 2017 was *** criteria in.luded active GI can.er diagn.sed at an. stage or treatmen.+/-6 mo of VTE diagn.sis,whom were prescribed 6 mo or more of DOACs or *** Chi-squared test was used for overall an. the Fisher exact test for pairwise comparison. of the proportion. of patien.s experien.in. recurren. VTE an. MB *** ratios were used to compare the relative odds of the occurren.e of the outcome given.exposure to the risk *** A total of 144 patien.s were prescribed an.icoagulation.in.which 106 fulfilled in.lusion.criteria apixaban.27.3%),rivaroxaban.34.9%)an. en.xaparin.37.7%),an. 38 were *** median.age was 66.5 years at GICA diagn.sis an. 67 years at CAVTE even.,with 62%males,80%Caucasian.70%stage IV,pan.reatic can.er(40.5%),30%Khoran. Score(≥3 poin.s),an. 43.5%on.active ***-four percen. of patien.s completed an.icoagulation.therapy(ran.e 1 to 43 mo).Recurren. VTE at 6 mo was n.ted in.7.5%(n.3),6.8%(n.2)an. 2.7%(n.1)of patien.s on.en.xaparin.apixaban.an. rivaroxaban.respectively(all P=n.).MB at 6 mo were 5%(n.2)for en.xaparin.6.8%(n.2)for apixaban.an. 21.6%(n.8)for rivaroxaban.overall P=0.048;vs LMWH P=0.0423;all other P=n.).Sign.fican. predictors of a prim

关键词： Direct oral an.icoagulan.s Low molecular weight heparin Gastroin.estin.l can.er Ven.us thromboembolism Can.er associated thrombosis Clin.cal risk

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Exertion.l heat illn.ss risk factors an. physiological respon.es of youth football players

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Journ.l of Sport an. Health Scien.e 2021年第1期10卷 91-98页

作者： Susan.W.Yeargin.John.J.Dickin.on.Dawn.M.Emerson.jessica Koller Ton. M.Torres-McGehee Zachary Y.Kerr Departmen. of Exercise Scien.e University of South CarolinaColumbiaSC 29208USA Palmetto Health/USC Orthopedic Cen.er Keenan High SchoolColumbiaSC 29203USA Departmen. of Health Sportand Exercise SciencesUniversity of KansasLawrenceKS 66045USA Surgi-Care In.. BostonMA 02115USA Departmen. of Exercise an. Sport Scien.e University of North CarolinaChapel HillNC 27599-8700USA

Objective:To determin. which in.rin.ic an. extrin.ic exertion.l heat illn.ss(EHI)risk factors exist in.youth American.football players an. observe perceptual an. physiological respon.es of players durin. even.s(games an. practices).Methods:Cross-section.l cohort study observin. 63 youth football players,varyin. in.*** variables were league(weightrestricted(WR,n.27)an. age-restricted(AR,n.36))an. even. *** variables were an.hropometrics,work-to-rest ratio,an. wet bulb globe *** variables in.luded preparticipation.examin.tion.an. un.form con.iguration.A subset of 16 players participated in.physiological variables(heart rate an. gastroin.estin.l temperature).Data collection.occurred on.7 AR an. 8 WR n.n.on.ecutive practices an. the first 3 games of the ***:Mean.values for an.hropometric variables were higher(pn.the AR league than.the WR *** time(χ^2(1,111)=4.232;p=0.039)an. rest time(χ^2(1,111)=43.41;pn.fican.ly greater for games,but ratios were sign.fican.ly higher for practices(χ^2(1,111)=40.62;pn.s(77%)observed were in.black an. red flag wet bulb globe temperature risk categories.A total of 57%of the players had a preparticipation.examin.tion.an. up to 82%of even.s observed were in.full *** gastroin.estin.l temperature an. heart rate respon.es ran.ed widely an. n. players reached critical ***:Extrin.ic(disproportion.te work ratios,en.iron.en.al con.ition.)an. in.rin.ic(higher body mass in.ex)EHI risk factors exist in.youth *** risk factors may be in.luen.ed by even. an. league *** youth football organ.zation. n.ed to create thorough guidelin.s that address EHI risk factors for local leagues to adopt.

关键词： Adolescen.s An.hropometrics Core temperature Heat exchan.e Pediatric Wet bulb globe temperature

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Spore Types an. Spore Production.of Ramularia areola for Screen.n. Cotton.Germplasm for Resistan.e

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American.Journ.l of Plan. Scien.es 2014年第15期5卷 2413-2417页

作者： jessica Volpon. Jan.in. n.Matos Larissa Girotto Marian. S.Maran.on. Rafael Galbieri Yeshwan. R.Mehta In.tituto Agron.mico do Paran.(IAPAR) LondrinaBrazil In.tituto Mato-Grossen.e do Algodao(IMA) Primavera do LesteBrazil

Spore production.ofRamularia areolahas always been.a difficult task. Brazilian.isolates ofR. areolaproduce spores of variable size an. shape. The typical spores are 3 septate, rarely 4 an. 5 septate, together with abun.an. sin.le celled oblon. to roun. bodies—a phen.men.n.n.t reported earlier forR. areola. Buddin. of spores is a con.in.ous process as observed in.our isolates. By repeated culturin. the pathogen.either ceases to produce typical spores or loses its pathogen.c character. To solve this problem, a techn.que was developed to produce large quan.ity of typical spores un.er laboratory con.ition.. Sporulatin. cultures produced on.Petri plates con.ain.n. V8 juice-agar were kept on.the laboratory ben.h till they became dry an. then.stored at 5°C for reisolation.an./or for production.of fresh in.culum. In.such dried cultures spores remain.viable for a period of over 12 mon.hs, an. hen.e isolates ofR. areolaorigin.tedfrom differen. geographic region. can.be main.ain.d in.sporulatin. form. Results of the presen. in.estigation.would aid cotton.breeders an. pathologists in.screen.n. germplasm resistan. toRamulariaan. in.other gen.tical studies un.er glasshouse con.ition..

关键词： Gossypium hirsutum Ramularia Leaf Blight Techn.ques Fruitin. Bodies

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Efficacy of On.oxin.Viusid on.the Reduction.of Adverse Reaction. to Chemotherapy an. Radiotherapy in.Patien.s Diagn.sed with Cervical Can.er an. En.ometrial Aden.carcin.ma

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Journ.l of Can.er Therapy 2020年第5期11卷 276-295页

作者： Raiza Ruiz Loren.e Daysi Hern.n.ez Durán.jessica García Viamon.es Juan.Len.e An.a Rosa Ortiz Reyes Eduardo San. n.vares Hospital “Ramón.Gon.ález Coro” Havana Cuba n.tion.l In.titute of On.ology an. Radiobiology of Cuba Havana Cuba Laboratorios Catalysis S.L. Madrid Spain

In.roduction. On.oxin.Viusid (OV) has shown.an.ioxidan., immun.modulatory an. an.i-tumour capabilities in.experimen.al studies on.human. an. an.mal subjects. Acute toxicity of Radiation.Therapy (RT) an. Chemotherapy (CT) in.patien.s with cervical can.er an. en.ometrial aden.carcin.ma impact quality of life an., therefore, outcomes of these therapies. Objective: To iden.ify On.oxin.Viusid’s efficacy in.reducin. acute toxicity produced by on.o-specific treatmen.s in.patien.s with cervical can.er an. en.ometrial aden.carcin.ma. Materials an. Methods: A con.rolled, ran.omised double-blin. phase II clin.cal trial was performed with a sample size of 63 patien.s distributed in.o 2 groups: on. receivin. the stan.ard treatmen. plus the On.oxin.Viusid n.trition.l supplemen. (OV group) an. an.ther receivin. the stan.ard treatmen. an. placebo (P group). The primary efficacy variable is the proportion.of secon.ary disruption. to acute adverse reaction. produced by RT an. CT. Results: The n.mber of patien.s sufferin. adverse even.s from chemotherapy was 20.6% less in.the OV group (70.0%) than.in.the placebo group (90.6%) (p = 0.04). We recorded con.isten.ly n.rmal values of haemoglobin.(-6.2 OV group vs -8.3 P group, p = 0.009), platelet coun. (-17.4 OV group vs -27.6 P group, p = 0.009) an. leukocytes (-31.8 OV group vs -41.4 P group, p = 0.025) in.the OV group, toleratin. 4 more cytostatic doses on.average than.the placebo group. Sign.fican. in.rease in.quality of life (QLQ-30) was registered in.the OV group with a large effect size on.such issues as emotion.l an. social fun.tion.(Cohen.s d = 0.9), as well as in.the reduction.of symptoms like dyspn.a 60%, in.omn.a 15% an. an.rexia 30% (item CX-2), (Cohen.s d = 0.98), which were higher than.the placebo group. Con.lusion.: OV admin.stration.reduces on.o-specific adverse even.s an. improves quality of life in.patien.s diagn.sed with cervical can.er an. en.ometrial aden.carcin.ma un.ergoin. radiation.therapy an. chemotherapy.

关键词： Cervical Can.er En.ometrial Aden.carcin.ma On.oxin.Viusid Radiotherapy Chemotherapy Adverse Effects

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Methodology of the data processin. with ICT solution. for the evaluation.of the en.rgy an. water savin.s

Methodology of the data processing with ICT solutions for th...

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The 2n. In.ern.tion.l Con.eren.e on.Green.Buildin. Techn.logies an. Materials(GBTM2012)

作者： Samuel Domín.uez jessica Fern.n.ez-Agüera Rocío Escan.n.Eugen.o Domín.uez In.titute of Architecture an. Buildin. Scien.e University of Seville2 Reina Mercedes Avenue41012 SevilleSpain

En.rgyTIC(Techn.logy,In.ormation.an. Commun.cation.services for en.agin. social housin. residen.s in.en.rgy an. water efficien.y) has put in.ormation.an. commun.cation.techn.logy(ICT) solution. in.place to provide en.-users with methods to mon.tor an. adapt their en.rgy an. water *** main.objective of this paper is to establish a methodology to an.lyze,process,an. organ.ze the user in.ormation.an. the en.rgy an. water con.umption.in.ormation.from the Span.sh pilot *** will work with three differen. layers of in.ormation. (1) data provided to the user,(2) data man.ged for the an.lysis,an.(3) data en.ered in.o the software "eeMeassure" to quan.ify the savin.s accordin. to the un.fied criteria of the European.Commission..

关键词： ICT solution. En.rgy Efficien.y En.rgy an. water savin.s En.rgy user’s feedback

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Allogen.ic an. autologous stem cell tran.plan.ation.with busulfan. cyclophosphamide, an. etoposide con.ition.n. therapy for relapsed/refractory n.n.Hodgkin.lymphoma

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Modern.Chemotherapy 2013年第4期2卷 57-65页

作者： n.elima Vidula An.rew M. Even. Iren. B. Helen.wski Borko Jovan.vic Jan. n. Win.er Jayesh Mehta Seema Sin.hal Stephan.e F. Williams Olga Fran.furt jessica K. Altman.Joan.e Mon.eal Leo I. Gordon Departmen. of Preven.ive Medicin. Northwestern University Chicago USA Division.of Hematology-On.ology Northwestern University Chicago USA Division.of Hematology-On.ology Northwestern University Chicago USA Division.of Hematology-On.ology The University of Massachusetts Medical School Worcester USA Division.of Hematology-On.ology University of California San Francisco USA

The optimal stem cell tran.plan.ation.(SCT) con.ition.n. therapy for relapsed/refractory n.n.Hodgkin.lymphoma (n.L) is n.t clearly defin.d. In.a retrospective an.lysis, we examin.d 25 patien.s with “high risk” relapsed/refractory n.L who received busulfan. cyclophosphamide, an. etoposide (Bu/Cy/VP16) con.ition.n. with autologous or allogen.ic SCT. The majority of patien.s had aggressive histology an. 52% had primary refractory n.L. Furthermore, 48% of patien.s had chemotherapy-resistan. disease at the time of SCT. Fifty-six percen. of patien.s un.erwen. allogen.ic SCT, while 44% had autologous SCT. The median.en.raftmen. time for n.utrophils an. platelets was 13.5 an. 14 days, respectively. The 100-day treatmen.-related mortality (TRM) was 16%, while the 2-year n.n.relapse mortality (n.M) rate was also 16%. At a median.follow-up of 15 mon.hs, the estimated 2-year disease-free survival (DFS) rate was 64% (95% con.iden.e in.erval (CI): 36%-82%) an. the estimated 2-year overall survival (OS) was 69% (95% CI: 40%-86%). Furthermore, the 2-year disease-specific survival (DSS) rate was 73% (95% CI: 40%-90%). Usin. Cox proportion.l hazard modelin., the In.ern.tion.l Progn.stic In.ex at time of relapse predicted DFS an. OS. Altogether, Bu/Cy/VP16 was associated with early TRM;however, late toxicities (in.ludin. n.M) were un.ommon.resultin. in.relatively good survival rates in.a high-risk relapsed/refractory n.L population.

关键词： Stem Cell Tran.plan.ation Busulfan Cyclophosphamide Etoposide n.n.Hodgkin Lymphoma

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