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Syn.hesis an. application. of lan.han.id complexes of pen.aden.ate an. hexaden.ate n.(5) an. n.(6) macrocycles:A review

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Journ.l of Rare Earths 2024年第1期42卷 1-15,I0001页

作者： Julio Corredoira-Vázquez Cristin. Gon.ález-Barreira Paula Oreiro-Martín.z An. M.García-Deibe jesús San.artín.Matalobos Matilde Fon.o Departamen.o de Química In.rgan.0} Facultade de QuímicaUniversidade de Santiago de CompostelaCampus Vida15782Santiago de CompostelaSpain Phan.om-g CICECO-Aveiro Institute of MaterialsDepartment of PhysicsUniversity of Aveiro3810-193AveiroPortugal In.titute of Materials(iMATUS) Universidade de Santiago de Compostela15782Santiago de CompostelaSpain

In.this paper,the lan.han.id complexes of n.(5) an. n.(6) macrocycle ligan.s,without pen.an. arms or addition.l heteroatoms,are *** review covers the period from 2015 to the curren. date,sin.e in.2014 Schiff base macrocyclic ligan.s in.orporatin. the pyridin. moiety,an. their complexes,were revised,an. in.2015 the chemistry of pen.aaza macrocycle ligan.s with rare earth metals was also *** an. phthalocyan.n. ligan.s are n.t in.luded in.this review,which primarily focuses on.complexes with Schiff bases an. amin.s without pen.an. arms or an. addition.l don.r other than.*** syn.hetic methods,structural characterization.based on.sin.le X-ray crystal data,an. properties of the lan.han.id complexes,with special atten.ion.to magn.to-structural correlation.,are presen.ed herein.

关键词： Lan.han.id n.(5),n.(6)macrocycle Coordin.tion.chemistry Chirality Biological activity Molecule magn.t

Morphometry an. Min.ral Con.en. in.the Seeds an. Soil of Two Species of Argemon. L.(Papaveraceae)in.the Cen.ral Part of the Chihuahuan.Desert

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Phyton.In.ern.tion.l Journ.l of Experimen.al Botan. 2024年第2期93卷 371-386页

作者： Perla Patricia Ochoa-García Jaime Sán.hez-Salas Ricardo Trejo-Calzada jesús JosafathQuezada-Rivera Fabián.García-Gon.ález Un.dad Region.l Un.versitaria de Zon.sÁridas BermejilloUniversidad Autónoma ChapingoDurango35230México Facultad de Cien.ias Biológicas Universidad Juárez del Estado de DurangoGómez PalacioDurango35010México

The gen.s Argemon. L.(Papaveraceae)is foun. widely distributed in.Mexico’s Chihuahuan.Desert(CD).Some species of this gen.s are of phytochemical or ethn.botan.0}l *** are in.dible plan.s con.idered as *** date they have n.t been.broadly studied;thus,their ecology is,to our kn.wledge,*** presen. work was cen.ered aroun. carryin. out a morphometric an.lysis an. the determin.tion.of min.rals in.the soil an. seeds of the wild population. of Argemon. at sites belon.in. to two ecoregion. of the CD in.*** April 2021 an. April 2022,seeds of Argemon. spp.,an. soil samples were collected at 10 sites of the *** seeds were selected un.er a ran.omized design.an. weight,len.th,diameter,thickn.ss,buoyan.y,an. min.ral con.en. were *** soil samples were obtain.d un.er the Mexican.regulation.n.M-021-RECn.T-2000,an. determin.tion. of min.ral con.en.,electrical con.uctivity,apparen. den.ity,an. soluble an.on. were *** in.ormation.obtain.d was grouped by variable,species,an. place of *** statistical tests con.isted of an.An.VA,Tukey mean. tests con.iderin. p≤0.05,an. a Prin.ipal Compon.n.s *** pleiacan.ha exhibited differen.es in.terms of weight(F=54.79,p=0.001),len.th(F=90.83,p=0.001),thickn.ss(F=104.89,p=0.001),an. diameter(F=155.82,p=0.001),an. the differen.es in.Argemon. mexican. were in.weight(F=46.71,p=0.001),thickn.ss(F=187.49,p=0.001),len.th(F=191.56,p=0.001),an. diameter(F=215.83,p=0.001).The evaluated seeds reached their maximal imbibition.velocity at 24 h of *** con.en. of the micro-an. macro-n.trien.s an.lyzed in.the seeds an. soil suggest a tight relation.with the morphometric characteristics of the seeds.

关键词： Micron.trien.s agricultural area semiarid zon. ecoregion buoyan.y

Myelin.histology:a key tool in.n.rvous system research

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n.ural Regen.ration.Research 2024年第2期19卷 277-281页

作者： Óscar Darío García-García Víctor Carriel jesús Chato-Astrain Departmen. of Histology Tissue Engineering GroupUniversity of Granada&Instituto de Investigación Biosanitaria ibs.GRANADAGranadaSpain

The myelin.sheath is a lipoprotein.rich,multilayered structure capable of in.reasin. con.uction.velocity in.cen.ral an. peripheral myelin.ted n.rve *** to the complex structure an. composition.of myelin.various histological techn.ques have been.developed over the cen.uries to evaluate myelin.un.er n.rmal,pathological or experimen.al ***,methods to assess myelin.in.egrity or con.en. are key tools in.both clin.0}l diagn.sis an. n.uroscien.e *** this review,we provide an.updated summary of the composition.an. structure of the myelin.sheath an. discuss some histological procedures,from tissue fixation.an. processin. techn.ques to the most used an. practical myelin.histological stain.n. *** the lipoprotein.n.ture of myelin.the main.features an. techn.0}l details of the differen. available methods that can.be used to evaluate the lipid or protein.compon.n.s of myelin.are described,as well as the precise ultrastructural techn.ques.

关键词： fluorescen.e microscopy histology light microscopy lipid histochemistry metallographic techn.ques myelin.histochemistry myelin.immun.histochemistry myelin.structure&composition myelin.ultrastructural evaluation tissue fixation.processin.

Twen.y years of population.dyn.mics in.European.beech-oak forest at their rear ran.e margin.an.icipate chan.es in.its structure an. composition

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Forest Ecosystems 2024年第3期11卷 358-370页

作者： álvaro Rubio-Cuadrado Iciar Alberdi Isabel Can.llas Fern.n.o Mon.es jesús Rodríguez-Calcerrada Rosan. López Guillermo G.Gordaliza María Valbuen.-Caraban. n.kos n.n.s Ramón.Perea Luis Gil Departamen.o de din.mica y gestion.forestal Instituto de Ciencias Forestales(ICIFOR-INIA)CSICCtra.La Coruna km 7.528040MadridSpain Departamen.o de Sistemas y Recursos n.turales Escuela Tecnica Superior de Ingeniería de MontesForestal y del Medio NaturalUniversidad Politecnica de Madrid.Ciudad Universitaria s/n28040MadridSpain School of Forestry an. n.tural En.iron.en. Aristotle University of ThessalonikiUniversity Campus54124ThessalonikiGreece

There is an.in.reasin. in.erest in.restorin. degraded forests,which occupy half of the forest *** the forms of restoration.passive restoration.which in.olves the elimin.tion.of degradin. factors an. the free evolution.of n.tural dyn.mics by applyin. min.mal or n. man.gemen.,is gain.n. *** dyn.mics is difficult to predict due to the in.luen.e of multiple in.eractin. factors such as climatic an. edaphic con.ition.,composition.an. abun.an.e of species,an. the succession.l character of these ***,we study the n.tural dyn.mics of a mixed forest located in.cen.ral Spain.which main.ain.d an.open.forest structure,due to in.en.ive use,un.il grazin. an. cuttin. were ban.ed in.the *** most frequen. woody species in.this forest are Fagus sylvatica,Quercus petraea,Quercus pyren.ica,Ilex aquifolium,Sorbus aucuparia,Sorbus aria an. Prun.s avium,with con.rastin. shade an. drought *** species are common.in.temperate European.deciduous forest an. are foun. here n.ar their southern.distribution.limit,except for *** order to an.lyze forest dyn.mics an. composition.three in.en.ories were carried out in.1994,2005 an. *** results show that,despite the Mediterran.an.in.luen.e,the n.tural dyn.mics of this forest has been.main.y determin.d by differen. levels of shade *** the aban.on.en. of grazin. an. cuttin.,*** expan.ed rapidly due to its lower shade toleran.e,whereas after can.py closure an. forest den.ification.shade-toleran. species gain.d groun.,particularly ***,despite its lower drought an. late-frost *** the curren. dyn.mics con.in.e,*** will overtake the rest of the species,which will be relegated to sites with shallow soils an. steep ***,all the multi-cen.en.ial beech trees,which are un.ergoin. a rapid mortality an. declin. process,will disappear.

关键词： Forest succession Secon.ary forest Woodlan. Mixed forest Competition Recruitmen.

Predictin. the clothin. in.ulation.through machin. learn.n. algorithms:A comparative an.lysis an. a practical approach

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Buildin. Simulation 2024年第5期17卷 839-855页

作者： Pablo Aparicio-Ruiz Elen. Barbadilla-Martin.Jose Guadix jesus Mun.zuri Grupo de In.en.eria de Organ.zacion Escuela Tecnica Superior de IngenieriaUniversidad de SevillaCamino de los Descubrimientos S/N41092SevilleSpain

Sin.e in.oor clothin. in.ulation.is a key elemen. in.thermal comfort models,the aim of the presen. study is proposin. an.approach for predictin. it,which could assist the occupan.s of a buildin. in.terms of recommen.ation. regardin. their *** that,a systematic an.lysis of in.ut variables is exposed,an. 13 regression.an. 12 classification.machin. learn.n. algorithms were developed an. *** results are based on.data from 3352 question.aires an. 21 in.ut variables from a field study in.mixed-mode office buildin.s in.*** temperature at 6 a.m.,in.oor air temperature,in.oor relative humidity,comfort temperature an. gen.er were the most relevan. features for predictin. clothin. *** comparin. machin. learn.n. algorithms,decision.tree-based algorithms with Boostin. techn.ques achieved the best *** proposed model provides an.efficien. method for forecastin. the clothin. in.ulation.level an. its application.would en.ail optimisin. thermal comfort an. en.rgy efficien.y.

关键词： clothin. in.ulation.simulation adaptive thermal comfort behavioural adaptive action. machin. learn.n.

Risk scores for allograft failure: Are they still useful in.liver recipien.s from don.tion.after circulatory death?

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World Journ.l of Tran.plan.ation 2024年第4期14卷 95-100页

作者： Mohamed H Mohamed Chairi Món.0} Mogollón.Gon.ález Jen.ifer Triguero Cabrera In.aculada Segura Jimén.z Maria T Villegas Herrera jesús M Villar del Moral Tran.plan. Surgery Division Department of SurgeryVirgen de las Nieves University HospitalGranada 18013AndalusiaSpain

BACKGROUn. Liver grafts from don.tion.after circulatory death(DCD)are associated with a higher risk of early graft dysfun.tion.determin.d by the warm ischemia an. cold ischemia *** is essen.ial to have precise criteria to iden.ify this complication.in.order to guide therapeutic *** To validate differen. graft an. recipien. survival scores in.patien.s un.ergoin. liver tran.plan.ation.LT)with DCD *** A retrospective an. observation.l un.cen.ric study was con.ucted on.65 LT patien.s with grafts obtain.d from con.rolled DCD don.rs from n.vember 2013 to n.vember *** Un.ted Kin.dom(UK)risk score,early allograft dysfun.tion.EAD)Olthoff score,an. model for early allograft fun.tion.MEAF)score were used to evaluate the risk of graft an. recipien. survival *** survival an.lysis purposes,we used the Kaplan.Meier method,an. the differen.es between.subgroups were compared usin. the log-ran.(Man.el-Cox)*** Sixty-five patien.s were in.luded in.the *** UK risk score did n.t demon.trate predictive capacity for recipien. or graft ***,in.don.rs aged over 70 years old(18.4%),it sign.fican.ly predicted graft survival(Pn. to Kaplan.Meier survival curves,graft survival rates at 6 mon.hs,2 years,an. 5 years in.the futility group dramatically decreased to 50%compared to the other groups(log-ran. 8.806,Pn. MEAF scores did n.t demon.trate predictive capacity for recipien. or graft *** on.Kaplan.Meier survival curves,patien.s with a MEAF score≥7 had a lower graft survival rate at 6 mon.hs,2 years,an. 5 years compared to patien.s with a lower MEAF score(log-ran. 4.667,Pn.LUSIOn.In.our series,both UK DCD risk score an. MEAF score showed predictive capability for graft survival.

关键词： Liver tran.plan.ation Don.tion.after circulatory death Early allograft dysfun.tion Risk scores Graft surviva

n.vel in.ights in.o D-Pin.tol based therapies:a lin. between.tau hyperphosphorylation.an. in.ulin.resistan.e

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n.ural Regen.ration.Research 2024年第2期19卷 289-295页

作者： Din. Medin.-Vera An.on.o jesús López-Gambero Juan.An.on.o n.varro Carlos San.uan.Elen. Baixeras Juan.Decara Fern.n.o Rodríguez de Fon.eca In.tituto de In.estigación.Biomédica de Málaga y Plataforma en.n.n.medicin.-IBIMA Plataforma BIOn.n. UGC Salud MentalMálagaSpain Facultad de Cien.ias Universidad de MálagaMálagaSpain CIBER En.ermedades Cardiovasculares(CIBERCV) Hospital Universitario Virgen de la VictoriaUGC del CorazónMálagaSpain Un.versity of Bordeaux INSERMNeurocentre MagendieBordeauxFrance Euron.tra S.L.Calle Johan.es Kepler MálagaSpain Departamen.o de Bioquímica y Biología Molecular Facultad de MedicinaUniversidad de MálagaMálagaSpain

Alzheimer’s disease is a n.urodegen.rative disorder characterized by the amyloid accumulation.in.the brain. of patien.s with Alzheimer’s *** pathogen.sis of Alzheimer’s disease is main.y mediated by the phosphorylation.an. aggregation.of tau *** the multiple causes of tau hyperphosphorylation.brain.in.ulin.resistan.e has gen.rated much atten.ion.an. in.sitols as in.ulin.sen.itizers,are curren.ly con.idered can.idates for drug *** presen. n.rrative review revises the in.eraction. between.these three elemen.s:Alzheimer’s disease-tau-in.sitols,which can.even.ually iden.ify targets for n.w disease modifiers capable of brin.in. hope to the million. of people affected by this devastatin. disease.

关键词： Alzheimer’s disease cyclin.depen.en. kin.se 5 diabetes D-Pin.tol in.sitols in.ulin.resistan.e kin.ses phosphorylation PI3K/Akt tau

Effect of Ultraviolet Radiation.on.Hsp70 Protein.Expression.in.HaCaT Cells

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World Journ.l of n.clear Scien.e an. Techn.logy 2024年第1期14卷 59-71页

作者： Sergio Hugo Sán.hez Rodríguez jesús Rodríguez Vergil Man.el Ven.n.io Muñoz Juárez Kevin.Said Ramírez Dávila Luis Martín.García Ortiz Germán.Flores Cortés Luz Elen. Vidales Rodríguez jesús Adrián.López David Alejan.ro García López Laboratorio de Biología Celular y n.urobiología Unidad Académica de Ciencias Biológicas Universidad Autónoma de Zacatecas Zacatecas México Laboatorio de Bacterias y Hon.os Filamen.osos Unidad Académica de Ciencias Biológicas Universidad Autónoma de Zacatecas Zacatecas México Laboratorio de MicroRn.s Unidad Académica de Ciencias Biológicas Universidad Autónoma de Zacatecas Zacatecas México

Ultraviolet radiation.by its wavelen.th is divided in.o: UVA, UVB an. UVC. On.y UVA an. UVB man.ge to pen.trate the ozon. layer, but due to an.hropological activities, all of them are capable of in.eractin. with human. to a greater or lesser exten., an. can.gen.rate adverse effects such as cellular stress when.in.eractin. with in.ra-an. extracellular biomolecules. The skin.is the first organ.in.con.act with UV radiation. an. the stress it gen.rates can.be an.lyzed by the expression.of a bioin.icator of cellular damage such as Hsp70. Therefore, the objective of the project was: to determin. the effect of UVA, UVB an. UVC radiation.on.HaCaT epithelial cells, by an.lyzin. the expression.of Hsp70. Materials an. methods: HaCaT cells were cultured in.vitro, which were irradiated with UVA, UVB an. UVC light at differen. doses, to subsequen.ly determin. the degree of Hsp70 expression.by Immun.detection.by PAGE-SDS an. Western.Blot. Results: Basal expression.of Hsp70 was observed in.n. irradiated HaCaT cells. When.HaCaT cells were irradiated with UVA, UVB, UVC, an.in.rease in.this Hsp70 protein.was observed. With UVA, a higher degree of expression.was observed at a time of 30 min.tes of irradiation. With UVB the highest expression.shifted to a time of 20 min.tes. With UVC, overexpression.was observed after 10 min.tes. Con.lusion. UV radiation.gen.rates cellular stress on.HaCaT cells, evaluated by the stress bioin.icator Hsp70. Accordin. to the wavelen.th of UV radiation. those that have a shorter wavelen.th have a greater poten.ial for cellular damage, such as UVC.

关键词： Ultraviolet A Light (UVA) Ultraviolet B Light (UVB) Ultraviolet C Light (UVC) Heat Shock Protein.70 (Hsp70) HaCaT

Targetin. harmful effects of n.n.excitatory amin. acids as an.altern.tive therapeutic strategy to reduce ischemic damage

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n.ural Regen.ration.Research 2025年第9期20卷 2454-2463页

作者： Victoria Jimén.z Carretero IrisÁlvarez-Merz Jorge Hern.n.ez-Campan. Sergei A.Kirov jesús M.Hern.n.ez-Guijo Departmen. of Pharmacology an. Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón.y Cajal In.titute for Health Research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain In.titute of n.urobiology Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Departmen. of n.uroscien.e an. Regen.rative Medicin.&Departmen. of n.urosurgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The in.olvemen. of the excitatory amin. acids glutamate an. aspartate in.ce rebral ischemia an. excitotoxicity is ***,the role of n.n.excitatory amin. acids in.brain.damage followin. a stroke or brain.trauma remain. largely *** release of amin. acids by n.crotic cells in.the ischemic core may con.ribute to the expan.ion.of the *** fin.in.s in.icated that the reversible loss of field excitato ry postsyn.ptic poten.ials caused by tran.ien. hypoxia became irreversible when.exposed to a mixture of just four n.n.excitatory amin. acids(L-alan.n.,glycin.,L-glutamin.,an. L-serin.)at their plasma *** amin. acids in.uce swellin. in.the somas of n.uron. an. astrocytes durin. hypoxia,alon. with perman.n. den.ritic damage mediated by n.methyl-D-aspartate *** n.methyl-D-aspartate receptors preven.ed n.uron.l damage in.the presen.e of these amin. acids durin. *** is likely that astroglial swellin. caused by the accumulation.of these amin. acids via the alan.n.-serin.-cystein. tran.porter 2 exchan.er an. system n.tran.porters activates volume-regulated an.on.chan.els,leadin. to the release of excitotoxin. an. subsequen. n.uron.l damage through n.methyl-D-aspartate receptor ***,previously un.ecogn.zed mechan.sms in.olvin. n.n.excitatory amin. acids may con.ribute to the progression.an. expan.ion.of brain.in.ury in.n.urological emergen.ies such as stroke an. traumatic brain.*** these pathways co uld highlight n.w therapeutic targets to mitigate brain.in.ury.

关键词： cell swellin. n.methyl-D-aspartate receptor n.n.excitatory amin. acids stroke syn.ptic tran.mission