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Spinel Castables for Steel Ladle Lining:In-Situ Versus Preformed

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China's Refractories 2012年第3期21卷 7-15页

作者： Andreas BUHR Marion SCHNABEL LONG Bin Reinhard EXENBERGER Christian RAMPITSCH jerry DUTTON Almatis GmbH Frankfurt Germany Qingdao Almatis Co. Ltd. Qingdao 266071 China Voestalpine Stahl GmbH Linz Austria Stourbridge United Kingdom

The paper discusses the difference in the formulation concepts of alumina - spinel （spinel containing ） and alumina - magnesia （ spin, el forming） castables and the influence on their physical properties. The individual property profile is discussed with respect to the requirements of refactory lining materials for the different zones of a steel ladle.

关键词： in-situ spinel preformed spinel steel ladle lining

Basophile:Accurate Fragment Charge State Prediction Improves Peptide Identification Rates

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Genomics, Proteomics & Bioinformatics 2013年第2期11卷 86-95页

作者： Dong wang Surendra Dasari Matthew C.Chambers jerry D.Holman Kan Chen Daniel C.Liebler Daniel j.Orton Samuel O.Purvine Matthew E.Monroe Chang Y.Chung Kristie L.Rose David L.Tabb Department of Biomedical Informatics Vanderbilt University Medical Center Division of Biomedical Statistics and Informatics Mayo Clinic Department of Biochemistry Vanderbilt University Medical Center Biological Sciences Division and Environmental Molecular Sciences Laboratory Pacific Northwest National Laboratory Department of Pharmacology Vanderbilt University Medical Center Vanderbilt-Ingram Cancer Center Vanderbilt University School of Medicine

In shotgun proteomics, database search algorithms rely on fragmentation models to pre- dict fragment ions that should be observed for a given peptide sequence. The most widely used strat- egy （Naive model） is oversimplified, cleaving all peptide bonds with equal probability to produce fragments of all charges below that of the precursor ion. More accurate models, based on fragmen- tation simulation, are too computationally intensive for on-the-fly use in database search algorithms. We have created an ordinal-regression-based model called Basophile that takes fragment size and basic residue distribution into account when determining the charge retention during CID/higher- energy collision induced dissociation （HCD） of charged peptides. This model improves the accuracy of predictions by reducing the number of unnecessary fragments that are routinely predicted for highly-charged precursors. Basophile increased the identification rates by 26% （on average） over the Naive model, when analyzing triply-charged precursors from ion trap data. Basophile achieves simplicity and speed by solving the prediction problem with an ordinal regression equation, which can be incorporated into any database search software for shotgun proteomic identification.

关键词： Fragmentation Basicity Fragment size Ordinal regression

犬尾田鼠在斑块生境中更喜好内部区域(英文)

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兽类学报 2008年第1期28卷 1-6页

作者： WOLFF jerry O BOND Monica L Department of Biological Sciences St. Cloud State University St. Cloud MN. 56301 USA PO Box 151172 San Rafael CA 94915 USA

我们在斑块化的景观中实验测定了犬尾田鼠(Microtus canicaudus)的生境喜好,验证下列假说:在一斑块生境中,与边缘区域相比,雌性田鼠喜好内部区域。在低密度和高密度时成年雌性的巢区在生境内部区域分别占100%和76%。高密度时在边缘区域... 详细信息

我们在斑块化的景观中实验测定了犬尾田鼠(Microtus canicaudus)的生境喜好,验证下列假说:在一斑块生境中,与边缘区域相比,雌性田鼠喜好内部区域。在低密度和高密度时成年雌性的巢区在生境内部区域分别占100%和76%。高密度时在边缘区域雌性的捕获率较低,这种差异在低密度时更突出。在高密度时通过选择性去除生境内部和边缘区域的一些雌体,边缘区域13只雌体中8只(占62%)的巢区发生从边缘到内部区域的转移,内部区域20只雌体中只有3只(占15%)的巢区向边缘区域转移。动物的繁殖率、生存和体重在两个区域之间没有差异。但是,边缘区域个体的巢区比内部区域的要小。这些结果支持一些关于其他啮齿动物的研究观察结果(如鼠平类和田鼠类),但与草原田鼠不同。因此在一斑块生境中,与边缘区域相比,长尾田鼠更喜好内部区域,边缘区域与内部区域的比率可潜在影响动物的生境选择,也可能会影响斑块化生境中的种群统计学特征。

关键词：边缘效应犬尾田鼠生境斑块巢区景观生态学

Introduction to and Comments on the Aarhus Convention

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The journal of Human Rights 2004年第1期3卷 32-37页

作者： jerry Z.LI UNDP China

Although regional inscope, the significance of theAarhus Convention is global.It is by far the most impres-sive elaboration of principle10 of the Rio Declaration,which stresses the need forcitizen's participation in envi-ronmental issues and foraccess to information on theenvironment held by publicauthorities. As such it is themost ambitious venture in thearea of 'environmentaldemocracy' so far undertak-en under the auspices of theUnited Nations.

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中文版Windows 98系统管理员宝典 G

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Loss of GSNOR1 Function Leads to Compromised Auxin Signaling and Polar Auxin Transport

丛书名：美国IDG“宝典”丛书

1998年

作者：（美）（j.霍尼克特）jerry Honeycutt 卢凌云等译

来源：畅想之星图书光盘版（南... 评论

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Molecular Plant 2015年第9期8卷 1350-1365页

作者： Ya-Fei Shi Da-Li wang Chao wang Angela Hendrickson Culler Molly A. Kreiser jayanti Suresh jerry D. Cohen jianwei Pan Barbara Baker jian-Zhong Liu College of Chemistry and Life Sciences Zhejiang Normal University Jinhua Zhejiang 321004 China Department of Plant and Microbial Biology University of California Berkeley Berkeley CA 94720 USA Department of Horticultural Science Microbial and Plant Genomics Institute University of Minnesota Saint Paul MN 55108 USA These authors contributed equally to this article.

Cross talk between phytohormones, nitric oxide （NO）, and auxin has been implicated in the control of plant growth and development. Two recent reports indicate that NO promoted auxin signaling but inhibited auxin transport probably through S-nitrosylation. However, genetic evidence for the effect of S-nitrosylation on auxin physiology has been lacking. In this study, we used a genetic approach to understand the broader role of S-nitrosylation in auxin physiology in Arabidopsis. We compared auxin signaling and transport in Col-0 and gsnorl-3, a loss-of-function GSNOR1 mutant defective in protein de-nitrosylation. Our results showed that auxin signaling was impaired in the gsnorl-3 mutant as revealed by significantly reduced DR5-GUS/ DR5-GFP accumulation and compromised degradation of AXR3NT-GUS, a useful reporter in interrogating auxin-mediated degradation of Aux/IAA by auxin receptors. In addition, polar auxin transport was compro- mised in gsnorl-3, which was correlated with universally reduced levels of PIN or GFP-PIN proteins in the roots of the mutant in a manner independent of transcription and 26S proteasome degradation. Our results suggest that S-nitrosylation and GSNORl-mediated de-nitrosylation contribute to auxin physiology, and impaired auxin signaling and compromised auxin transport are responsible for the auxin-related morpho- logical phenotypes displayed by the gsnorl-3 mutant.

关键词： phytohormone cross talk S-nitrosoglutathione reductase (GSNOR) S-nitrosylation auxin signaling,auxin transport Arabidopsis

Mathematical modeling of malaria transmission dynamics in humans with mobility and control states

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Infectious Disease Modelling 2023年第4期8卷 1015-1031页

作者： Gbenga Adegbite Sunday Edeki Itunuoluwa Isewon jerry Emmanuel Titilope Dokunmu Solomon Rotimi jelili Oyelade Ezekiel Adebiyi Covenant University Bioinformatics Research Covenant UniversityOtaNigeria Department of Computer and Information Sciences Covenant UniversityOtaNigeria Department of Mathematics Covenant UniversityOtaNigeria Department of Biochemistry Covenant UniversityOtaNigeria Covenant Applied Informatics and Communications-African Centre of Excellence Covenant UniversityOtaOgun StateNigeria Division of Applied Bioinformatics German Cancer Research Center(DKFZ)HeidelbergGermany

Malaria importation is one of the hypothetical drivers of malaria transmission dynamics across the *** studies on malaria importation focused on the effect of the use of conventional malaria control strategies as approved by the World Health Organization(WHO)on malaria transmission dynamics but did not capture the effect of the use of traditional malaria control strategies by vigilant *** order to handle the aforementioned situation,a novel system of Ordinary Differential Equations(ODEs)was developed comprising the human and the malaria vector *** of the system was carried out to assess its quantitative *** novel computational algorithm used to solve the developed system of ODEs was implemented and benchmarked with the existing Runge-Kutta numerical solution ***,simulations of different vigilant conditions useful to control malaria were carried *** novel system of malaria models was well-posed and epidemiologically meaningful based on its quantitative *** novel algorithm performed relatively better in terms of model simulation accuracy than *** the best model-fit condition of 98%vigilance to the use of conventional and traditional malaria control strategies,this study revealed that malaria importation has a persistent impact on malaria transmission *** lieu of this,this study opined that total vigilance to the use of the WHO-approved and traditional malaria management tools would be the most effective control strategy against malaria importation.

关键词： Malaria importation Traditional malaria control Ordinary differential equation Quantitative properties Novel algorithm Runge-Kutta

Dietary copper supplementation modulates performance and lipid metabolism in meat goat kids

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journal of Integrative Agriculture 2023年第1期22卷 214-221页

作者： ZHANG Yan-mei AO De LEI Kai-wen Lin XI jerry W.SPEARS SHI Hai-tao HUANG Yan-ling YANG Fa-long Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Exploitation of Ministry of Education/Key Laboratory of Animal Science of State Ethnic Affairs Commission College of Animal and Veterinary SciencesSouthwest Minzu UniversityChengdu 610041P.R.China Department of Animal Science North Carolina State UniversityRaleigh 27695USA

Forty-eight male Lezhi black goat kids with similar body weight((12.09±1.70)kg)and age((60±5)d)were used to determine the effect of dietary copper(Cu),in the form of reagent grade Cu sulfate(CuSO4∙5H2O),on performance,serum lipid profile,and the relative mRNA abundance of genes involved in lipid *** kids were stratified by body weight and randomly assigned to one of 4 treatment *** treatment consisted of 12 replicate pens with each pen containing one goat *** groups received the basal diet with no supplemental Cu(control),basal diet plus 10 mg of Cu kg^(-1)of dry matter(DM),basal diet plus 20 mg of Cu kg^(-1)of DM,or basal diet plus 30 mg of Cu kg^(-1)of *** were housed individually in pens and fed a high-concentrate pelleted diet for 60 *** daily gain,average daily feed intake and feed:gain of goats were not affected by dietary Cu supplementation(P>0.10).No differences were detected in serum total cholesterol,triglyceride,and high density lipoprotein cholesterol concentrations of goat kids fed with different Cu concentrations(P>0.05).However,serum low density lipoprotein cholesterol concentrations decreased linearly(P=0.01)as the concentration of dietary Cu *** fat content of longissimus muscle increased(P=0.002)quadratically and liver Cu concentrations increased(P<0.001)linearly as dietary Cu concentration *** with the control,dietary supplementation of 20 mg Cu kg^(-1)DM decreased the relative mRNA abundance of fatty acid-binding protein 4(P=0.01)and lipoprotein lipase(P=0.05),and tended to decrease the relative mRNA abundance of carnitine palmitoyltransferase I(P=0.06)in longissimus muscle of *** relative mRNA abundance of peroxisome proliferator-activated receptor alpha(P<0.001),carnitine acetyltransferase(P=0.001),and carnitine palmitoyltransferase Ⅰ(P=0.001)were also decreased in liver by Cu *** results indicate that dietary supplementation of Cu modified lipid

关键词： copper gene expression goats lipid metabolism growth performance

Glycolysis regulates gene expression by promoting the crosstalk between H3K4 trimethylation and H3K14 acetylation in Saccharomyces cerevisiae

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journal of Genetics and Genomics 2019年第12期46卷 561-574页

作者： Yinsheng Wu Shihao Zhang Xuanyunjing Gong Qi Yu Yuan Zhang Mingdan Luo Xianhua Zhang jerry L.Workman Xilan Yu Shanshan Li State Key Laboratory of Biocatalysis and Enzyme Engineering College of Life SciencesHubei UniversityWuhanHubei430062China Stowers Institute for Medical Research 1000 E.50th StreetKansas CityMO64110USA

Cells need to coordinate gene expression with their metabolic states to maintain cell homeostasis and ***,how cells transduce nutrient availability to appropriate gene expression response via histone modifications remains largely ***,we report that glucose specifically induces histone H3K4 trimethylation(H3K4me3),an evolutionarily conserved histone covalent modification associated with active gene transcription,and that glycolytic enzymes and metabolites are required for this in?*** glycolysis supplies S-adenosylmethionine for histone methyltransferase Setl to catalyze H3K4me3,glucose induces H3K4me3 primarily by inhibiting histone demethylase jhd2-catalyzed H3K4 *** provides acetyl-CoA to stimulate histone acetyltransferase Gcn5 to acetylate H3K14,which then inhibits the binding of jhd2 to chromatin to increase *** repressing jhd2-mediated H3K4 demethylation,glycolytic enzymes regulate gene expression and cell survival during chronological ***,our results elucidate how cells reprogram their gene expression programs in response to glucose availability via histone modifications.

关键词： Gene transcription Glycolysis Histone modifications Yeast H3K4me3 H3K14ac