检索结果-南通市图书馆

Factors Prognosis of ebola Virus Disease at the Wonkifong ebola Treatment Center, Coyah, Guinea

在线全文

学校读者我要写书评

暂无评论

Advances in Infectious Diseases 2018年第3期8卷 139-150页

作者： Mamadou Saliou Sow Alioune Camara Boushab Mohamed Boushab Mamadou Oury Safiatou Diallo Kadio Jean-jacques Olivier Kadio Ismael Camara Alseny Modet Camara Mandy Kader Kondé Moussa Seydi Infectious and Tropical Diseases Department University Hospital Center of Conakry Conakry Guinea Department of Public Health Faculty of Medicine University of Conakry Conakry Guinea Internal Medecine and Infectious Diseases Department Centre Hospitalier of Kiffa Kiffa Mauritania Infectious and Tropical Diseases Department Fann Teaching University Hospital Dakar Senegal

Background: The ebola Virus epidemic epidemic in Guinea was marked by its rapid spread in the capital, forcing the authorities to build several ebola treatment centers including Wonkifong (Coyah), Conakry. Objective: To evaluate the case fatality rate of ebola Virus Disease in this center and to identify associated factors. Patients and Method: There is a prospective study at wonkifong ebola treatment center from January 1st, 2014 to April 30th, 2015. All patients diagnosed with an ebola Virus Disease from January 1st, 2014 to April 30th, 2015 were enrolled in this study. Kaplan-Meier curves and multivariate regression model were used to analyze factors associated with death. Results: 216 patients were included, the mean age was 30.52 ± 17 years and 53.2% were female. The average time between admission to the ebola treatment center and the onset of signs was 5.13 ± 3.8 days. The average period of stay in the ebola Treatment Center was 12.64 ± 11.31 days and duration median of death after admission in Wonkifong eTC was 11 days. According to the source, more than half of the patients were from Forécariah, i.e. 60.2% (n = 134). The case fatality rate was 64.4%. This rate was 72.0% in Dubréka, 65.1% in Coyah and 64.6% in Forécariah. The factors independently associated with ebola Virus Disease death were signs of diarrhea [OR = 2.22 (1.17 - 4.20)], anorexia [OR= 0.40 (0.19 - 0.81)] and period of patients stay in eTC [OR = 0.96 (0.93 - 0.99)]. Conclusion: These results show that the fatality rate linked to the ebola virus disease remains high. The factors independently associated with death were Diarrhea, anorexia and period between beginning of illness and date of latest news. Biological monitoring and resuscitation seem interesting for the reduction of this mortality.

关键词： ebola Disease Lethality Wonkifong Guinea

Study of Copper Thin Films Resistivity by Using Van der Pauw Method at Low Frequencies

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Applied Sciences 2022年第11期12卷 1944-1953页

作者： Désiré Allassem B. Mahamout Mahamat Adoum Kriga Yaya Dagal Dari Mahamat Hassan Béchir Mahamat Ahmat Taha Yacoub Nassian Nimir Jean Pierre Chatelon Jean-jacques Rousseau Research Laboratory in electrical engineering Electronics and Energy (LR3E) Higher National Institute of Sciences and Techniques of Abeche (INSTA) Abeche Chad Hubert Curien Laboratory (LabHC) Jean Monnet University Saint-Etienne France University of Ndjamena Ndjamena Chad

The objective of this work research is the use of four-point measurements and so-called Van Der Pauw methods in measuring the resistivity of copper thin films widely used in the manufacture of planar components such as inductor and others. Aligned configuration and square configuration are commonly used to measure thin films resistivity before use. But differences in values between the two configurations according to frequency and thickness were observed according to the authors. Measurements with both configurations on the same thin films must make it possible to know measurements evolution as a function of frequency and thickness. The observation of measuring frequency ranges of each configuration and the minimum thicknesses to have solid copper resistivity are the main contributions of the paper. This electrical characterization is carried out on copper thin films deposited on alumina substrates (50 mm × 20 mm × 635 μm) using RF sputtering technique. Copper thin films with various thicknesses (3.3 μm, 3.6 μm and 5.2 μm) were characterized. Low-frequency electrical characterization of these thin films was performed by four-point measurement method and using an HP 4284A type LCRmeter over the frequency range of 20 Hz to 1 MHz. Van der Pauw’s method was used to calculate resistivity. These studies allowed us to know influence of measurement configurations and influence of parameters such as frequency and thickness of the copper thin films on resistivity.

关键词： Thin Film Characterization Van der Pauw Resistivity Thickness LCRmeter

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

加拿大与美国都市圈内政府治理差异分析

城市观察 2009年第1期1卷 51-62页

作者：让·皮埃尔·科林[加] 雅克·勒韦勒[加] 克莱尔·波特哈[加] （加拿大）世界区域城市与城市间研究科技部不详

本文探讨地方公共机构尤其是地方行政机构如何改变其结构和手段,以应对新的地区化和都市化的挑战。通过分析35个美国和加拿大的城市群,评估政府机构在多大程度上采用了怎样的方法去规划、实施和监督都市化政策,并重点研究都市圈机构和... 详细信息

本文探讨地方公共机构尤其是地方行政机构如何改变其结构和手段,以应对新的地区化和都市化的挑战。通过分析35个美国和加拿大的城市群,评估政府机构在多大程度上采用了怎样的方法去规划、实施和监督都市化政策,并重点研究都市圈机构和都市圈的财税政策。

关键词：北美都市圈地方政府机构改革地方财政政策

Frequency of Antibiotic Resistance of escherichia coliand Klebsiella pneumoniaeby Production of TOHO-Type β-Lactamases at Saint Camille Hospital, Ouagadougou (Burkina Faso)

在线全文

学校读者我要写书评

暂无评论

Advances in Microbiology 2021年第12期11卷 713-722页

作者： Serge Sougué Amana Mètuor-Dabiré Djénéba Ouermi Yasmine Rahimatou Wend-Kouni Tiemtoré Bénao Stéphanie Lynseh Carine Sita Théodora Mahoukèdè Zohoncon Yasmine Aminata Bangré elie Kabré jacques Simporé Department of Biochemistry and Microbiology Faculty of Applied Science and Technology Biomolecular Research Centre (CERBA/LABIOGENE) UFR-SVT Joseph KI-ZERBO University Ouagadougou Burkina Faso National Public Health Laboratory of Ouagadougou Ouagadougou Burkina Faso University of Dedougou Dedougou Burkina Faso Saint Thomas Aquinas University (USTA) Saint Camille Hospital of Ouagadougou Ouagadougou Burkina Faso

extended-spectrum β-lactamase (eSBL) appeared some years after the introduction in hospital environment of unhydrolysable or extended-spectrum cephalosporins. Several studies have been reported on the blaTeM, blaCTX-M and blaSHV genes in eSBL producing enterobacteria, however, very few studies reported in the literature were related to blaCTX-M subgroup blaTOHO. TOHO enzymes were responsible for healthcare-associated infections in hospitals and in the community. In Burkina Faso, data related to these types of enzymes were scarce. The purpose of this study was to detect TOHO enzymes in escherichia coli and Klebsiella pneumoniae in order to know the prevalence of infections related to bacterial resistance due to TOHO enzymes at Saint Camille Hospital of Ouagadougou (Burkina Faso). The study was conducted firstly by microbiological identification of eSBLs-producing by escherichia coli and Klebsiella pneumoniae using API 20 e gallery;secondly the antibiogram was performed by the diffusion method and finally the molecular characterization was made by conventional PCR to search for the blaTOHO gene. The visualization of the specific bands was made using the ultraviolet lamp (Gene Flash) for the photography of the gels. Data were entered and analyzed using excel 2013 and ePI Info version 6.0 software. A p-value ered as significant. We obtained at all 39 strains constituted by 21 (53.8%) escherichia coli and 18 (46.2%) Klebsiella pneumoniae. Molecular characterization showed the presence of the blaTOHO gene in 25 bacterial strains (64.1%). It was therefore established in this study the existence of blaTOHO gene at Saint Camille Hospital in Ouagadougou in Burkina Faso. Our study made it possible to know the distribution of the blaTOHO gene in escherichia coli and Klebsiella pneumoniae.

关键词： Antibiotic Resistance Bacteria eSBL Genes TOHO

Pregnancies Outcome after Assisted Reproductive Technology: A Multicenter Case Control Study in a Low Income Setting Douala, Cameroon

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Open Journal of Obstetrics and Gynecology 2021年第6期11卷 720-731页

作者： Tchente Nguefack Charlotte Bourdanne Tekouake Didier T. Nana Njamen Nda Mefo’o Jean Pierre ekono Michel Roger essome Henri Tsingaing Kamgaing jacques Gwet Bell ernestine Sandjon Guy Halle ekane edie Gregory Faculty of Medicine and Pharmaceutical Science University of Douala Douala Cameroon Department of Gynecology and Obstetrics Douala General Hospital Douala Cameroon Faculty of Health Sciences University of Buea Buea Cameroon Department of Biology Douala General Hospital Douala Cameroon Bel Air Plus Clinic Douala Douala Cameroon Odyssée Medical Clinic Douala Douala Cameroon Clinique de l’Aéroport Douala Douala Cameroon

The objective was to assess the outcome of pregnancies after assisted reproductive technology (ART). It was a case-control study carried out in four health facilities in Douala-Cameroon, over a period of five years. The cases were pregnant women who conceived through ART and the controls were those who conceived naturally. Cases and controls were matched for maternal age and parity (one case for two controls). A logistic regression analysis was used to compute Odds ratios. Statistical significance was set at 0.05. A total of 174 women who conceived through ART and 348 who conceived naturally were enrolled. Some independent factors associated with ART were: age over 45 years [aOR: 7.55; 95% CI (1.55 - 36.76);p: 0.01], twin pregnancies [aOR: 16.55; e="font-family:Verdana;">e

关键词： Pregnancy Outcome Assisted Reproductive Technology Douala

一种兼具高强度、高应变硬化率和高塑性的新型钛合金

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界有色金属 2015年第3期40卷 31-34页

作者：逯冉 F.Sun J.Y.Zhang M.Marteleur C.Brozek e.F.Rauch M.Veron P.Vermaut P.J.jacques F.Prim 北京中色鑫桥商贸中心 Institut de Recherche de Chimie Paris CNRS UMR 8247–Chimie Paris Tech 11 rue Pierre et Marie Curie75005 Paris France Universite'Catholique de Louvain Institute of MechanicsMaterials and Civil Engineering IMAP Place Sainte Barbe 2B-1348 Louvain-la-Neuve Belgium Univ.Grenoble Alpes SIMAP F-38000 Grenoble France CNRS SIMAP F-38000 Grenoble France Universite' Catholique de Louvain Institute of MechanicsMaterials and Civil Engineering IMAP Place Sainte Barbe 2B-1348 Louvain-la-Neuve Belgium

本研究设计了一种三元亚稳β钛合金Ti-9Mo-6W(质量百分数)。由于该合金变形时会联合出现相变诱发塑性效应和孪晶诱发塑性效应,使该合金的加工硬化速率可以接近2 100MPa,均匀变形能力高于35%。为了深入了解Ti-9Mo-6W合金的变形过程,对其... 详细信息

本研究设计了一种三元亚稳β钛合金Ti-9Mo-6W(质量百分数)。由于该合金变形时会联合出现相变诱发塑性效应和孪晶诱发塑性效应,使该合金的加工硬化速率可以接近2 100MPa,均匀变形能力高于35%。为了深入了解Ti-9Mo-6W合金的变形过程,对其变形过程中的显微组织进行了详细分析。结果表明,Ti-9Mo-6W合金变形过程中存在{332}机械孪晶、应力诱发ω相、应力诱发α"马氏体等不同的变形机制,综合作用使合金内部最终形成了具有高度协合性的复杂网络变形组织。

关键词：钛合金孪晶马氏体相变转变组织

Detection of ARV-Resistant Mutants in HIV-1-Infected Individuals in a Context of Systematic Switching to an Association Based on Dolutegravir in Abidjan, Côte d’Ivoire

在线全文

学校读者我要写书评

暂无评论

American Journal of Molecular Biology 2024年第3期14卷 138-151页

作者： Odegue Kpadraux Danielle Kakou-Ngazoa Solange Dechi Jean-jacques Renaud Diallo Zelica Sina Kouamé Mireille Sylla Aboubacar Tossea Koui Stéphane Kouakou Venance Adagba Marius Apia N’Chouo Kouamé Basile Touré Offianan André Dosso Mireille Molecular Biology Platform Institut Pasteur Abidjan Cte dIvoire Laboratory of the Regional Blood Transfusion Center Yamoussoukro Cte dIvoire Department of Infectious and Tropical Diseases University Hospital Treichville Abidjan Cte dIvoire Laboratory of the Regional Blood Transfusion Center San-Pdro Cte dIvoire Department of epidemic Virus Institut Pasteur Abidjan Cte dIvoire Department of Parasitology Mycology Institut Pasteur Abidjan Cte dIvoire Department of Bacteriology-Virology Institut Pasteur Abidjan Cte dIvoire

The emergence of antiretroviral resistance mutations represents a major threat to the achievement of national and global goals for the elimination of HIV-1 infection. The global strategy in 2019 in Cte d'Ivoire is a new national policy for the management of people living with HIV with the administration of dolutegravir (DTG)-based fixed-dose combination. The aim of our study was to evaluate HIV-1 resistance to antiretrovirals (ARVs) in infected adult subjects in Cte d’Ivoire in the context of a systematic switch to a DTG-based combination. Between February 2022 and October 2023, a cross-sectional survey with random sampling was conducted in 06 services caring for people living with HIV. A total of 139 participants were included in the study. Adults with a viral load ≥ 1000 copies/mL were tested for HIV-1 ARV resistance mutations. Molecular analyses were performed using protocol of ANRS-MIe (National Agency for Research on AIDS and emerging infectious diseases). The interpretation is performed by HIVGRAD (https://***/cms/grade/). The frequencies of HIV-1 resistance to non-nucleotide reverse transcriptase inhibitors (NNRTIs), nucleotide reverse transcriptase inhibitors (NRTIs), integrase inhibitors (IINTs) and protease inhibitors (PIs) were 82%, 73%, 19% and 11% respectively. The main mutations observed in the different classes were K103N (45%), M184V (64%), e157Q (19%) and L10V/M46I/A71V/I54V (6%) respectively. This study reveals the emergence of resistance to DTG-based fixed-dose combinations, favored by high rates of resistance to NRTIs and NNRTIs. This finding underlines the need for enhanced viral load monitoring and HIV-1 genotyping tests to guide the choice of NRTIs for combination therapy. In addition, monitoring for mutations to second-generation NRTIs is essential, given the scale-up of DTG-based regimens currently underway in Cte d’Ivoire.

关键词： Resistant Mutants Dolutegravir HIV-1 Antiretrovirals Côte d’Ivoire

1999年8月17日伊兹米特地震之后马尔马拉海地区的地震危险性

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

世界地震译丛 2001年第3期32卷 17-23页

作者： A. Hubert-Ferrari A. Barka e. jacques S. S. Nalbant B. Meyer R. Armijo P. Tapponnier G. C. P. King 万永革中国地震局防灾技术高等专科学校

1999年8月17日,在北安纳托利亚断层上伊斯坦布尔以东100 km的伊兹米特市附近发生了7.4级的破坏性大地震。这个1600 km长的板块边界(Barka,1992,1999)以平均为2～3cm/a的速率滑动(Reilinger,et al,1997;Hubert,1998;hrmijo,et al,1999),历史上为多次破坏性地震的发生地点(Ambraseys,1970;Ambraseys and Finkel,1991)。仅20世纪沿此断层就破裂了900 km的长度(Ambraseys,1970)。利用地震产生的应力变化的模型(King,et al,1994),结合活动断层分布图分析,预测的1999年伊兹米特地震的震中区确实是大地震发生的可能位置(Nalbant,et al,1998;stein,et al,1997)。本文展示证据说明,1999年的地震本身显著改变了先前地震断层相互作用产生的应力分布(Nalbant,et al,1998;stein,et al,1997)。我们的新应力模型考虑了此地区自1700年后发生的震级大于6的所有地震(Ambraseys,et al,1991),以及由GPS数据约束的地震之间的长期应力变化(straub,et al,1997)。这些模型提供了北安纳托利亚断层长期时空行为的一致图象,并指出在今后数十年内,伊斯坦布尔以南的马尔马拉海之下将可能发生震级等于或大于伊兹米特地震的两个地震。

关键词：北安纳托利亚断层马尔马拉海分支地震危险性伊兹米特地震

Antimicrobial activity of calcium hydroxide and chlorhexidine on intratubular Candida albicans

在线全文

学校读者我要写书评

暂无评论

International Journal of Oral Science 2013年第1期5卷 32-36页

作者： Ronan jacques Rezende Delgado Thaís Helena Gasparoto Carla Renata Sipert Claudia Ramos Pinheiro Ivaldo Gomes de Moraes Roberto Brandao Garcia Marco Antnio Hungaro Duarte Clóvis Monteiro Bramante Srgio Aparecido Torres Gustavo Pompermaier Garlet Ana Paula Campanelli Norberti Bernardineli Department of Biological Sciences Bauru School of DentistryUniversity of Sao Paulo Department of Operative Dentistry Endodontics and Dental MaterialsBauru School of DentistryUniversity of Sao Paulo

This study investigated the efficacy of calcium hydroxide and chlorhexidine gel for the elimination of intratubular Candida albicans (***).Human single-rooted teeth contaminated with *** were treated with calcium hydroxide,2%chlorhexidine gel, calcium hydroxide plus 2%chlorhexidine gel,or saline(0.9%sodium chloride) as a positive *** samples obtained at depths of 0-100 and 100-200μm from the root canal system were analyzed for *** load by counting the number of colony forming units and for the percentage of viable *** using fluorescence ***,the antimicrobial activity of calcium hydroxide and the 2%chlorhexidine gel was evaluated by counting the number of colony forming *** 14 days of intracanal medication,there was a significant decrease in the number of *** colony forming units at a depth of 0-100μm with chlorhexidine treatment either with or without calcium hydroxide compared with the calcium hydroxide only ***,there were no differences in the number of colony forming units at the 100-200μm depth for any of the medications *** viability was also evaluated by vital staining techniques and fluorescence microscopy *** activity against *** significantly increased at both depths in the chlorhexidine groups with and without calcium hydroxide compared with the groups treated with calcium hydroxide *** with only chlorhexidine or chlorhexidine in combination with calcium hydroxide were effective for elimination of ***.

关键词： calcium hydroxide Candida albicans chlorhexidine endodontics