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Spontaneous splenic rupture associated with scrub typhus: a case report

Infectious Diseases of Poverty 2024年第1期13卷 97-97页

作者： Hong Pil hwang Kyoung Min Kim Hyojin Han jeong-hwan hwang Department of Surgery Jeonbuk National University Hospital Jeonbuk National University Medical School Jeonju Republic of Korea Research Institute of Clinical Medicine of Jeonbuk National University Jeonju Korea Biomedical Research Institute of Jeonbuk National University Hospital Jeonju Korea Department of Pathology Jeonbuk National University Hospital Jeonbuk National University Medical School Jeonju Republic of Korea Department of Internal Medicine Jeonbuk National University Hospital Jeonbuk National University Medical School Jeonju-Si Republic of Korea

Background Scrub typhus,an acute febrile disease with mild to severe,life-threatening manifestations,potentially presents with a variety of complications,including pneumonia,acute respiratory distress syndrome,cardiac arrhyth-mias(such as atrial fibrillation),myocarditis,shock,peptic ulcer,gastrointestinal bleeding,meningitis,encephalitis,and renal *** the various complications associated with scrub typhus,splenic rupture has rarely been reported,and its mechanisms are *** study reports a case of scrub typhus-related spontaneous splenic rupture and identifies possible mechanisms through the gross and histopathologic *** presentation A 78-year-old man presented to our emergency room with a 5-day history of fever and skin *** physical examination,eschar was observed on the left upper abdominal *** abdomen was not ten-der,and there was no history of *** Orientia tsutsugamushi antibody titer using the indirect immunofluo-rescent antibody test was 1:*** Day 6 of hospitalization,he complained of sudden-onset left upper abdominal quadrant pain and showed mental *** vital signs were a blood pressure of 70/40 mmHg,a heart rate pf 140 beats per min,and a respiratory rate of 20 breaths per min,with a temperature of 36.8℃.There were no signs of gastrointestinal bleeding,such as hematemesis,melena,or *** Turner's sign was suspected during an abdominal *** ultrasonography showed retroperitoneal bleeding,so an emergency exploratory laparotomy was performed,leading to a diagnosis of hemoperitoneum due to splenic rupture and a *** patient had been taking oral doxycycline(1o0 mg twice daily)for 6 days;after surgery,this was dis-continued,and intravenous azithromycin(500 mg daily)was *** arrhythmia associated with azithro-mycin was ***,renal failure with hemodialysis,persistent hyperbilirubinemia,and multiorgan failure *** patient did not recover and d

关键词： Scrub typhus Complication Splenic rupture

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Hemophagocytic lymphohistiocytosis triggered by relapsing polychondritis:A case report

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World Journal of Orthopedics 2024年第8期15卷 813-819页

作者： Mi-Ran Han jeong-hwan hwang Seungah Cha So-Yeon Jeon Kyu Yun Jang Namsu Kim Chang-Hoon Lee Department of Internal Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Pathology Jeonbuk National University Medical SchoolJeonju 54907South Korea Department of Laboratory Medicine Jeonbuk National University Medical SchoolJeonju 54907South Korea

BACKGROUND Hemophagocytic lymphohistiocytosis(HLH)is a rare,life-threatening disorder caused by abnormal histiocytes and T cell *** adults,it is predominantly associated with infections,cancers,and autoimmune *** polychondritis(RP),another rare disease,is diagnosed based on symptoms without specific tests,featuring cartilage inflammation characterized by swelling,redness,and pain,rarely inducing *** SUMMARY A 74-year-old woman visited the emergency room with a fever of 38.6℃.Blood tests,cultures,and imaging were performed to evaluate *** showed increased fluorescent antinuclear antibody levels and mild cytopenia,with no other specific *** revealed lymph node enlargement was observed;however,biopsy results were *** re-evaluation of the physical exam,inflammatory signs suggestive of RP were observed in the ears and nose,prompting a tissue biopsy for ***,persistent fever accompanied by cytopenia prompted a bone marrow examination,revealing hemophagocytic *** finding no significant results in blood culture,viral markers,and tissue examination of enlarged lymph nodes,HLH was diagnosed by *** involved methylprednisolone followed by *** two months,bone marrow examination confirmed resolution of hemophagocytosis,with normalization of hyperferritinemia and *** Thorough physical examination enabled diagnosis and treatment of HLH trig gered by RP in patients presenting with fever of unknown origin.

关键词： Hemophagocytic lymphohistiocytosis Relapsing polychondritis Autoimmune disease Fever of unknown origin Steroid Case report

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Aligned Ion Conduction Pathway of Polyrotaxane‑Based Electrolyte with Dispersed Hydrophobic Chains for Solid‑State Lithium–Oxygen Batteries

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Nano-Micro Letters 2025年第2期17卷 169-186页

作者： Bitgaram Kim Myeong‑Chang Sung Gwang‑Hee Lee Byoungjoon hwang Sojung Seo Ji‑Hun Seo Dong‑Wan Kim Department of Materials Science and Engineering Korea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea School of Civil Environmental and Architectural EngineeringKorea University145 Anam‑RoSeongbuk‑GuSeoul 02841Republic of Korea Materials Science and Chemical Engineering Center Institute for Advanced Engineering(IAE)Yongin 17180Republic of Korea

A critical challenge hindering the practical application of lithium–oxygen batteries(LOBs)is the inevitable problems associated with liquid electrolytes,such as evaporation and safety *** study addresses these problems by proposing a modified polyrotaxane(mPR)-based solid polymer electrolyte(SPE)design that simultaneously mitigates solvent-related problems and improves ***-SPE exhibits high ion conductivity(2.8×10^(−3)S cm^(−1)at 25℃)through aligned ion conduction pathways and provides electrode protection ability through hydrophobic chain *** this mPR-SPE into solid-state LOBs resulted in stable potentials over 300 *** situ Raman spectroscopy reveals the presence of an LiO_(2)intermediate alongside Li_(2)O_(2)during oxygen *** situ X-ray diffraction confirm the ability of the SPE to hinder the permeation of oxygen and moisture,as demonstrated by the air permeability *** present study suggests that maintaining a low residual solvent while achieving high ionic conductivity is crucial for restricting the sub-reactions of solid-state LOBs.

关键词： Solid polymer electrolyte Lithium-oxygen batteries Polyrotaxane ion conductivity Hydrophobic chain

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Apolipoprotein A-I binding protein-mediated neuroprotection in glaucomatous neuroinflammation and neurodegeneration

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Neural Regeneration Research 2025年第5期20卷 1414-1415页

作者： Sinwoo hwang Seunghwan Choi Soo-Ho Choi Keun-Young Kim Yury I.Miller Won-Kyu Ju Hamilton Glaucoma Center and Shiley Eye Institute The Viterbi Family Department of OphthalmologyUniversity of California San DiegoLa JollaCAUSA Department of Medicine University of California San DiegoLa JollaCAUSA National Center for Microscopy and Imaging Research Department of NeurosciencesUniversity of California San DiegoLa JollaCAUSA

Glaucoma is a multifactorial eye disorder that can cause vision loss and irreversible blindness,affecting individ uals aged 40 to 80 yea rs *** to the aging population,it is expected that the number of people affected by glaucoma will surpass 111 million by 2040 as the disease becomes more *** primarily contributes to optic nerve axon loss and the progressive degeneration of retinal ganglion cells (RGCs),subsequently leading to vision impairment.

关键词： irreversible pass primarily

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Saccharomyces boulardii as a single trigger of food protein-induced enterocolitis syndrome: Seven case reports

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World Journal of Clinical Cases 2025年第6期13卷 35-40页

作者： Jin-Bok hwang Hyo-jeong Jang Department of Pediatrics Keimyung University School of MedicineDongsan Medical CenterDaegu 42601South Korea

BACKGROUND Food protein-induced enterocolitis syndrome(FPIES)is the most serious type of non-immunoglobulin E(IgE)-mediated food allergic reaction manifesting as sepsis-like symptom,which can lead to *** boulardii(***),a probiotic prescribed frequently in clinical settings,has been reported to trigger FPIES in an infant with soy-triggered *** this report,we describe a new clinical FPIES in which *** was the sole triggering factor of acute FPIES adverse reaction in seven healthy *** SUMMARY Seven FPIES cases triggered by only *** were gathered from 2011 to the *** of the patients had previously experienced any allergic reaction to cow’s milk,soy,or complementary *** age of the patients was 4-10-months old,and the symptoms of FPIES developed after ingestion of ***,which is mostly prescribed for the treatment of gastroenteritis or antibiotic-associated *** patients experienced severe repetitive vomiting 1-3 hours after *** *** lethargy,marked pallor,and cyanosis were also *** IgE-mediated hypersensitivity developed in any *** was followed by initial intense vomiting in approximately 5-10 hours after *** ingestion,and only one case showed bloody,purulent,and foul-smelling *** patients stabilized quickly,mostly within 6 *** got all improved within 24 hours after discontinuation of *** *** can be the sole trigger of acute FPIES and be prescribed cautiously even in healthy children without FPIES.

关键词： Food protein-induced enterocolitis syndrome Food hypersensitivity Saccharomyces boulardii Probiotics Child Case report

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RIGHT MEAN FOR THEα-z BURES-WASSERSTEIN QUANTUM DIVERGENCE

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Acta Mathematica Scientia 2023年第5期43卷 2320-2332页

作者： Miran jeong Jinmi hwang Sejong KIM Department of Mathematics Chungbuk National UniversityCheongju 28644Korea Department of Mathematics Sungkyunkwan UniversitySuwon 16419Korea

The optimization problem to minimize the weighted sum ofα-z Bures-Wasserstein quantum divergences to given positive definite Hermitian matrices has been *** call the unique minimizer theα-z weighted right mean,which provides a new non-commutative version of generalized mean(H?lder mean).We investigate its fundamental properties,and give many interesting operator inequalities with the matrix power mean including the Cartan ***,we verify the trace inequality with the Wasserstein mean and provide bounds for the Hadamard product of two right means.

关键词： Rényi relative entropy Bures-Wasserstein quantum divergence right mean power mean Cartan mean Wasserstein mean

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Data Augmentation Using Contour Image for Convolutional Neural Network

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Computers, Materials & Continua 2023年第6期75卷 4669-4680页

作者： Seung-Yeon hwang jeong-Joon Kim Department of Computer Engineering Anyang UniversityAnyang-si14058Korea Department of ICT Convergence Engineering Anyang UniversityAnyang-si14058Korea

With the development of artificial intelligence-related technologies such as deep learning,various organizations,including the government,are making various efforts to generate and manage big data for use in artificial ***,it is difficult to acquire big data due to various social problems and restrictions such as personal information *** are many problems in introducing technology in fields that do not have enough training data necessary to apply deep learning ***,this study proposes a mixed contour data augmentation technique,which is a data augmentation technique using contour images,to solve a problem caused by a lack of ***,a famous convolutional neural network(CNN)architecture,and CIFAR-10,a benchmark data set,are used for experimental performance evaluation to prove the superiority of the proposed *** to prove that high performance improvement can be achieved even with a small training dataset,the ratio of the training dataset was divided into 70%,50%,and 30%for comparative *** a result of applying the mixed contour data augmentation technique,it was possible to achieve a classification accuracy improvement of up to 4.64%and high accuracy even with a small amount of data *** addition,it is expected that the mixed contour data augmentation technique can be applied in various fields by proving the excellence of the proposed data augmentation technique using benchmark datasets.

关键词： Data augmentation image classification deep learning convolutional neural network mixed contour image benchmark dataset

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A Deep Learning Hierarchical Ensemble for Remote Sensing Image Classification

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Computers, Materials & Continua 2022年第8期72卷 2649-2663页

作者： Seung-Yeon hwang jeong-Joon Kim Department of Computer Engineering Anyang UniversityAnyang-si14028Korea Department of ICT Convergence Engineering Anyang UniversityAnyang-si14028Korea

Artificial intelligence,which has recently emerged with the rapid development of information technology,is drawing attention as a tool for solving various problems demanded by society and *** particular,convolutional neural networks(CNNs),a type of deep learning technology,are highlighted in computer vision fields,such as image classification and recognition and object *** these CNN models requires a large amount of data,and a lack of data can lead to performance degradation problems due to *** CNN architecture development and optimization studies become active,ensemble techniques have emerged to perform image classification by combining features extracted from multiple CNN *** this study,data augmentation and contour image extraction were performed to overcome the data shortage *** addition,we propose a hierarchical ensemble technique to achieve high image classification accuracy,even if trained from a small amount of ***,we trained the UCMerced land use dataset and the contour images for each image on pretrained VGGNet,GoogLeNet,ResNet,DenseNet,and *** then apply a hierarchical ensemble technique to the number of cases in which each model can be *** experiments were performed in cases where the proportion of training datasets was 30%,50%,and 70%,resulting in a performance improvement of up to 4.68%compared to the average accuracy of the entire model.

关键词： Image classification deep learning CNNs hierarchical ensemble UC-Merced land use dataset contour image

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A Universal Activation Function for Deep Learning

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Computers, Materials & Continua 2023年第5期75卷 3553-3569页

作者： Seung-Yeon hwang jeong-Joon Kim Department of Computer Engineering Anyang UniversityAnyang-si14028Korea Department of ICT Convergence Engineering Anyang UniversityAnyang-si14028Korea

Recently,deep learning has achieved remarkable results in fields that require human cognitive ability,learning ability,and reasoning *** functions are very important because they provide the ability of artificial neural networks to learn complex patterns through *** activation functions are being studied to solve problems such as vanishing gradients and dying nodes that may occur in the deep learning ***,it takes a lot of time and effort for researchers to use the existing activation function in their ***,in this paper,we propose a universal activation function(UA)so that researchers can easily create and apply various activation functions and improve the performance of neural *** can generate new types of activation functions as well as functions like traditional activation functions by properly adjusting three *** famous Convolutional Neural Network(CNN)and benchmark datasetwere used to evaluate the experimental performance of the UA proposed in this *** compared the performance of the artificial neural network to which the traditional activation function is applied and the artificial neural network to which theUA is *** addition,we evaluated the performance of the new activation function generated by adjusting the hyperparameters of *** experimental performance evaluation results showed that the classification performance of CNNs improved by up to 5%through the UA,although most of them showed similar performance to the traditional activation function.

关键词： Deep learning activation function convolutional neural network benchmark datasets universal activation function

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Improving acoustical characteristics of a Gothic cathedral using simple public address system： A case study of Nlyeong-dong Cathedral in Seoul, Korea

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Frontiers of Architectural Research 2017年第1期6卷 17-28页

作者： In hwan hwang Won Gab Choi RPG Korea Diffusor Systems Inc. Seoul 05706 Korea

In the present study, improving acoustical characteristics of a Gothic cathedral （Myeong-dong Cathedral, which is the first built Western Gothic-style architecture in Korea） using simple public address system were investigated. Acoustical measurements were conducted at 11 selected points inside the cathedral and seven acoustical parameters were calculated： sound pressure level （SPL）： 64.6 dBA （the measurement value with regard to the omni-directional speaker sound source）; 74.5 dBA （the measurement value with regard to the public address speaker sound source）, early decay time （EDT）： 4.04 s; 3.76 s, reverberation time （RT6o）： 3.58 s; 3.89 s, clarity （Cso）： -6.2 dB; -2.8 dB, definition （D50）： 18%; 29%, initial time delay gap （ITDG）： 47 ms; 23 ms, and rapid speech transmission index （RASTI）： 32%; 42%. Parameters showed that the acoustical characteristics of a typical Gothic cathedral include rich reverberation and diffusive sound fields. Meanwhile, there was improved speech intelligibility when using simple public address system. Based on subjective evaluation, there was overall satisfaction with voice and music recognition and the highest satisfaction with clarity with respect to voice recognition and with reverberation with respect to music recognition. This is a good solution of optimized acoustic environment through harmony between natural reverberation and reinforced clarity using simple public address system.

关键词： Gothic cathedral Acoustical character-istics Pubtic address system Ctarity Reverberation

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